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The map label for this gene is argD [H]

Identifier: 158334631

GI number: 158334631

Start: 1450607

End: 1451869

Strand: Direct

Name: argD [H]

Synonym: AM1_1461

Alternate gene names: 158334631

Gene position: 1450607-1451869 (Clockwise)

Preceding gene: 158334630

Following gene: 158334638

Centisome position: 22.3

GC content: 51.78

Gene sequence:

>1263_bases
GTGAGCCCTACTGAACTTGCTCAAGATCCGTCTGCGGTATCCGCTCAATCCTTTAGTGCCACCAACTTTGATCAGGATGT
AATGACCACTTACGGTCGTTTCCCCATCGCCCTAGAGCGAGGACAAGGTTGTCGCGTCTGGGACACAGATGGGCAAGAGT
ATCTAGATTTTGTCGCCGGGATTGCCACCTGCACCTTGGGCCATGCTCATCCTGCCCTAGTGGCAGCAGTTACGGCCCAA
ATTCAAACCCTCCACCATGTCTCTAATCTGTATTACATCCCCCCACAGGGTGATCTCGCCCATTGGCTGACCCAGCACTC
CTGTGCCGATCGCGCCTTTTTCTGTAATTCAGGGGCGGAGGCCAACGAAGGGGCAATCAAACTAGCCCGGAAGTATGCCC
ATACAGTTTTGAATATTGAGCAGCCGATCATCTTGACGGCGGATGCTAGCTTTCATGGCCGGACCCTAGCCACTATTACC
GCTACCGCACAGCCGAAGTATCAAAAGAATTTTGATCCGCTGGTGCCTGGATTTGTGTATGTGCCGTTTAACGATTTGGC
CGCCCTCAAGGATAAAATCGCCACCTTAGATCACGACCAACGACGAGTTGCAGCTATCCTCCTAGAACCTTTGCAGGGAG
AAGGAGGGGTGCGCCCCGGACAACTGGAATACTTCCAAGGCGTACGCCAGATTTGCGATCAGACTGGAATCTTGCTGATT
CTGGATGAGGTTCAGGTCGGCATTGGCCGAACCGGAAAACTCTGGGGGTATCAGAATCTAGGTATTGAACCCGATGTGTT
TACCCTAGCGAAAGGGTTGGCGGGGGGCATCCCAATTGGGGCCATGCTCAGCAAAGAATTTTGCAGTGTTTTACAACCGG
GAGACCATGCCAGCACCTTTGGGGGAAATCCCTTTGTCTGTGCTGCGGCCCTAGCCGTCCTCGATACGCTGGAAACTGAA
AATTTACTAGACAATTCCGCCCAGCGAGGAGAACAGTTACGGGCAGGACTGCATACGATTCAATCCCAATATCCAAACCT
AATTGCTGAAGTTCGAGGATGGGGGCTGATTAATGGCTTGGTTTTGAAGGATGAGATTGAACTTACTTCGATTGAAGTGA
TTAAAGCAGCGATGGAAGCAGGTTTACTACTCGTTCCAGCTGGCCCCAAGGTTGTTCGCTTCGTGCCTCCCTTAGTCGTT
AGTGAGGGAGAGGTGGATAAAGCTCTGCAAACCGTCCGAAAAGTGTTGGCTGAACTGGGTTAA

Upstream 100 bases:

>100_bases
AATTAGCCTGTATTAATTGGGTCAAAGCTGGATTGGATCGCAACTTACAAAAATCTGCCTCTACAATGTAAGTCAACCTT
TCGTCCGTGCAGGAGTGCTT

Downstream 100 bases:

>100_bases
AGCGGTCAGGGATATTGCACTATCCCTCTGTGCCTGGTTTGCTTTGGCAGAGGAAATGTTGGCGATCTAGCCATTCCCAA
AGAGAAGCGAATATCACCTT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSPTELAQDPSAVSAQSFSATNFDQDVMTTYGRFPIALERGQGCRVWDTDGQEYLDFVAGIATCTLGHAHPALVAAVTAQ
IQTLHHVSNLYYIPPQGDLAHWLTQHSCADRAFFCNSGAEANEGAIKLARKYAHTVLNIEQPIILTADASFHGRTLATIT
ATAQPKYQKNFDPLVPGFVYVPFNDLAALKDKIATLDHDQRRVAAILLEPLQGEGGVRPGQLEYFQGVRQICDQTGILLI
LDEVQVGIGRTGKLWGYQNLGIEPDVFTLAKGLAGGIPIGAMLSKEFCSVLQPGDHASTFGGNPFVCAAALAVLDTLETE
NLLDNSAQRGEQLRAGLHTIQSQYPNLIAEVRGWGLINGLVLKDEIELTSIEVIKAAMEAGLLLVPAGPKVVRFVPPLVV
SEGEVDKALQTVRKVLAELG

Sequences:

>Translated_420_residues
MSPTELAQDPSAVSAQSFSATNFDQDVMTTYGRFPIALERGQGCRVWDTDGQEYLDFVAGIATCTLGHAHPALVAAVTAQ
IQTLHHVSNLYYIPPQGDLAHWLTQHSCADRAFFCNSGAEANEGAIKLARKYAHTVLNIEQPIILTADASFHGRTLATIT
ATAQPKYQKNFDPLVPGFVYVPFNDLAALKDKIATLDHDQRRVAAILLEPLQGEGGVRPGQLEYFQGVRQICDQTGILLI
LDEVQVGIGRTGKLWGYQNLGIEPDVFTLAKGLAGGIPIGAMLSKEFCSVLQPGDHASTFGGNPFVCAAALAVLDTLETE
NLLDNSAQRGEQLRAGLHTIQSQYPNLIAEVRGWGLINGLVLKDEIELTSIEVIKAAMEAGLLLVPAGPKVVRFVPPLVV
SEGEVDKALQTVRKVLAELG
>Mature_419_residues
SPTELAQDPSAVSAQSFSATNFDQDVMTTYGRFPIALERGQGCRVWDTDGQEYLDFVAGIATCTLGHAHPALVAAVTAQI
QTLHHVSNLYYIPPQGDLAHWLTQHSCADRAFFCNSGAEANEGAIKLARKYAHTVLNIEQPIILTADASFHGRTLATITA
TAQPKYQKNFDPLVPGFVYVPFNDLAALKDKIATLDHDQRRVAAILLEPLQGEGGVRPGQLEYFQGVRQICDQTGILLIL
DEVQVGIGRTGKLWGYQNLGIEPDVFTLAKGLAGGIPIGAMLSKEFCSVLQPGDHASTFGGNPFVCAAALAVLDTLETEN
LLDNSAQRGEQLRAGLHTIQSQYPNLIAEVRGWGLINGLVLKDEIELTSIEVIKAAMEAGLLLVPAGPKVVRFVPPLVVS
EGEVDKALQTVRKVLAELG

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=391, Percent_Identity=35.8056265984655, Blast_Score=264, Evalue=1e-70,
Organism=Homo sapiens, GI284507298, Length=305, Percent_Identity=37.3770491803279, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI13994255, Length=441, Percent_Identity=27.6643990929705, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI37574042, Length=422, Percent_Identity=29.1469194312796, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI226442705, Length=422, Percent_Identity=28.1990521327014, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI24119277, Length=420, Percent_Identity=29.0476190476191, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226442709, Length=391, Percent_Identity=28.9002557544757, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI188536080, Length=435, Percent_Identity=26.6666666666667, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI38679950, Length=435, Percent_Identity=26.6666666666667, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI38679946, Length=435, Percent_Identity=26.6666666666667, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1789759, Length=409, Percent_Identity=40.3422982885086, Blast_Score=318, Evalue=5e-88,
Organism=Escherichia coli, GI1788044, Length=396, Percent_Identity=42.1717171717172, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI145693181, Length=383, Percent_Identity=37.0757180156658, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1789016, Length=408, Percent_Identity=34.3137254901961, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1787560, Length=405, Percent_Identity=35.0617283950617, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1786991, Length=407, Percent_Identity=27.2727272727273, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786349, Length=326, Percent_Identity=28.5276073619632, Blast_Score=109, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=394, Percent_Identity=35.5329949238579, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI25144274, Length=286, Percent_Identity=34.965034965035, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI32564660, Length=439, Percent_Identity=29.8405466970387, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=27.7389277389277, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17541228, Length=455, Percent_Identity=27.032967032967, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=37.1069182389937, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6324432, Length=402, Percent_Identity=37.5621890547264, Blast_Score=274, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6323470, Length=429, Percent_Identity=34.032634032634, Blast_Score=235, Evalue=8e-63,
Organism=Saccharomyces cerevisiae, GI6321456, Length=441, Percent_Identity=25.8503401360544, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324386, Length=450, Percent_Identity=22.8888888888889, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357415, Length=394, Percent_Identity=34.5177664974619, Blast_Score=255, Evalue=4e-68,
Organism=Drosophila melanogaster, GI161085790, Length=428, Percent_Identity=28.5046728971963, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI28574759, Length=430, Percent_Identity=27.906976744186, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI21356575, Length=422, Percent_Identity=28.6729857819905, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281366494, Length=441, Percent_Identity=26.3038548752834, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24667139, Length=441, Percent_Identity=26.3038548752834, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24667143, Length=441, Percent_Identity=26.3038548752834, Blast_Score=118, Evalue=9e-27,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 45215; Mature: 45084

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPTELAQDPSAVSAQSFSATNFDQDVMTTYGRFPIALERGQGCRVWDTDGQEYLDFVAG
CCCHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCCEEECCCCHHHHHHHHH
IATCTLGHAHPALVAAVTAQIQTLHHVSNLYYIPPQGDLAHWLTQHSCADRAFFCNSGAE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHCCCEEEECCCCC
ANEGAIKLARKYAHTVLNIEQPIILTADASFHGRTLATITATAQPKYQKNFDPLVPGFVY
CCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCHHCCCCCCCCCEEE
VPFNDLAALKDKIATLDHDQRRVAAILLEPLQGEGGVRPGQLEYFQGVRQICDQTGILLI
ECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
LDEVQVGIGRTGKLWGYQNLGIEPDVFTLAKGLAGGIPIGAMLSKEFCSVLQPGDHASTF
EECHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCC
GGNPFVCAAALAVLDTLETENLLDNSAQRGEQLRAGLHTIQSQYPNLIAEVRGWGLINGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCE
VLKDEIELTSIEVIKAAMEAGLLLVPAGPKVVRFVPPLVVSEGEVDKALQTVRKVLAELG
EEECCCCHHHHHHHHHHHHCCEEEECCCCCEEEECCCEEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPTELAQDPSAVSAQSFSATNFDQDVMTTYGRFPIALERGQGCRVWDTDGQEYLDFVAG
CCHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCCEEECCCCHHHHHHHHH
IATCTLGHAHPALVAAVTAQIQTLHHVSNLYYIPPQGDLAHWLTQHSCADRAFFCNSGAE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHCCCEEEECCCCC
ANEGAIKLARKYAHTVLNIEQPIILTADASFHGRTLATITATAQPKYQKNFDPLVPGFVY
CCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCHHCCCCCCCCCEEE
VPFNDLAALKDKIATLDHDQRRVAAILLEPLQGEGGVRPGQLEYFQGVRQICDQTGILLI
ECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
LDEVQVGIGRTGKLWGYQNLGIEPDVFTLAKGLAGGIPIGAMLSKEFCSVLQPGDHASTF
EECHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCC
GGNPFVCAAALAVLDTLETENLLDNSAQRGEQLRAGLHTIQSQYPNLIAEVRGWGLINGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCE
VLKDEIELTSIEVIKAAMEAGLLLVPAGPKVVRFVPPLVVSEGEVDKALQTVRKVLAELG
EEECCCCHHHHHHHHHHHHCCEEEECCCCCEEEECCCEEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7929012; 11759840 [H]