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The map label for this gene is gufA [H]

Identifier: 158334612

GI number: 158334612

Start: 1432738

End: 1433511

Strand: Direct

Name: gufA [H]

Synonym: AM1_1442

Alternate gene names: 158334612

Gene position: 1432738-1433511 (Clockwise)

Preceding gene: 158334611

Following gene: 158334617

Centisome position: 22.03

GC content: 52.2

Gene sequence:

>774_bases
ATGAATCTGATCGTAGTGGGGTCAATCGCTAGCCTAATCGCTGGGTTGGCAACAGGCATCGGTGCATTACCCGTATTATT
CGTCAAAACCCTGACGGATCGTTTGCAAGGTATTTTTTTGGGCTTTGGCGGTGGGGTTATGTTGGCCGCCACTGCCTTTT
CCCTGATTGCGCCGGGAACAGACCTGGCTATGGGTCAAGGTAATACTGAAACCCAAGCAGCTTTAATTATGGTGCTGGGT
ATTTTGCTGGGAGGTGGGTTCCTCTGGCTAGCCCACAACAACTTTCCCCACGAACACTTCTTCAAAGGTCAAGAAGGCCC
GTCAACCCCTAACTTGGCTCGCATCTGGCTATTTGTGGTCGCCATCACCCTGCACAATTTCCCGGAGGGGATGGCGGTGG
GGGTAGGTTTTAGTGGCGGCTCTTTATCCAGCGGCATTGCTCTTGCCATTGGCATCGGCTTGCAAAATATGCCCGAAGGA
CTGGTGGTAGCCATCGCTCTGCGGTCCCTTAACTATTCATCCCTCTATGCCCTAGGCGTTGCCTGTCTCACCGGCTTAGT
CGAGCCCATAGGTGGTGTTGTGGGGGCTAGCATTATTAGCCTGGCTCAACCCCTTTTGCCCTGGGCAATGGCTTTTGCAG
CAGGCGCAATGCTGTTCGTTATCAGTGACGAAATTATCCCCGAAACTAGCCGTAAAGGCATTCAACAGGAAGGTACCCTC
GGAATCATGCTGGGATTTGTGGTGATGATGTACTTAGATGTTGCTCTAGGGTAA

Upstream 100 bases:

>100_bases
CGCTGACCCTGGCAGCATTATCCCGCATGCCCATTTCTAAAGTGATGGAATTATACCCAGGGTCATCCCCAATGCACCCT
CCTTTGGAGCTTGACGCTGA

Downstream 100 bases:

>100_bases
TCGGTTGAGAACAAGAGCCTAGGGTTTACCTTCTGGCTAAAGCCGTTATGCAACGAGGGGAAAGGCAGCAGCCAAAGACC
AGCCAAAAAATAATGCACTG

Product: ZIP Zinc transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNLIVVGSIASLIAGLATGIGALPVLFVKTLTDRLQGIFLGFGGGVMLAATAFSLIAPGTDLAMGQGNTETQAALIMVLG
ILLGGGFLWLAHNNFPHEHFFKGQEGPSTPNLARIWLFVVAITLHNFPEGMAVGVGFSGGSLSSGIALAIGIGLQNMPEG
LVVAIALRSLNYSSLYALGVACLTGLVEPIGGVVGASIISLAQPLLPWAMAFAAGAMLFVISDEIIPETSRKGIQQEGTL
GIMLGFVVMMYLDVALG

Sequences:

>Translated_257_residues
MNLIVVGSIASLIAGLATGIGALPVLFVKTLTDRLQGIFLGFGGGVMLAATAFSLIAPGTDLAMGQGNTETQAALIMVLG
ILLGGGFLWLAHNNFPHEHFFKGQEGPSTPNLARIWLFVVAITLHNFPEGMAVGVGFSGGSLSSGIALAIGIGLQNMPEG
LVVAIALRSLNYSSLYALGVACLTGLVEPIGGVVGASIISLAQPLLPWAMAFAAGAMLFVISDEIIPETSRKGIQQEGTL
GIMLGFVVMMYLDVALG
>Mature_257_residues
MNLIVVGSIASLIAGLATGIGALPVLFVKTLTDRLQGIFLGFGGGVMLAATAFSLIAPGTDLAMGQGNTETQAALIMVLG
ILLGGGFLWLAHNNFPHEHFFKGQEGPSTPNLARIWLFVVAITLHNFPEGMAVGVGFSGGSLSSGIALAIGIGLQNMPEG
LVVAIALRSLNYSSLYALGVACLTGLVEPIGGVVGASIISLAQPLLPWAMAFAAGAMLFVISDEIIPETSRKGIQQEGTL
GIMLGFVVMMYLDVALG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577422, Length=172, Percent_Identity=48.2558139534884, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI229577418, Length=172, Percent_Identity=48.2558139534884, Blast_Score=141, Evalue=4e-34,
Organism=Escherichia coli, GI1789419, Length=252, Percent_Identity=29.3650793650794, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507805, Length=302, Percent_Identity=34.4370860927152, Blast_Score=158, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24652846, Length=149, Percent_Identity=48.3221476510067, Blast_Score=130, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 26381; Mature: 26381

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIVVGSIASLIAGLATGIGALPVLFVKTLTDRLQGIFLGFGGGVMLAATAFSLIAPGT
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHCCCC
DLAMGQGNTETQAALIMVLGILLGGGFLWLAHNNFPHEHFFKGQEGPSTPNLARIWLFVV
CEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHH
AITLHNFPEGMAVGVGFSGGSLSSGIALAIGIGLQNMPEGLVVAIALRSLNYSSLYALGV
HHHHHCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHH
ACLTGLVEPIGGVVGASIISLAQPLLPWAMAFAAGAMLFVISDEIIPETSRKGIQQEGTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHCCCHHHCCCCCCCCH
GIMLGFVVMMYLDVALG
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLIVVGSIASLIAGLATGIGALPVLFVKTLTDRLQGIFLGFGGGVMLAATAFSLIAPGT
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHCCCC
DLAMGQGNTETQAALIMVLGILLGGGFLWLAHNNFPHEHFFKGQEGPSTPNLARIWLFVV
CEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHH
AITLHNFPEGMAVGVGFSGGSLSSGIALAIGIGLQNMPEGLVVAIALRSLNYSSLYALGV
HHHHHCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHH
ACLTGLVEPIGGVVGASIISLAQPLLPWAMAFAAGAMLFVISDEIIPETSRKGIQQEGTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHCCCHHHCCCCCCCCH
GIMLGFVVMMYLDVALG
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]