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The map label for this gene is gcp

Identifier: 158334611

GI number: 158334611

Start: 1431659

End: 1432741

Strand: Direct

Name: gcp

Synonym: AM1_1441

Alternate gene names: 158334611

Gene position: 1431659-1432741 (Clockwise)

Preceding gene: 158334607

Following gene: 158334612

Centisome position: 22.01

GC content: 50.78

Gene sequence:

>1083_bases
ATGGCAACAGTTTTAGCAATTGAAACGAGTTGTGATGAAACTGCCGCTGCAGTTGTAAAAAAACGTCACATTTTAAGTAA
TATTGTTGCATCCCAAATCGACATTCACCGTCCCTATGGAGGGGTGGTGCCAGAGGTTGCCTCTCGCCACCATGTGGAGT
CCATCAATGATGTCGTTAGCGAAGCCTTATCCCAAGCCCAGATAGATTGGCCAGATATTGATGGGATCGCTGTCACTTGT
GCCCCGGGGCTGGTGGGCGCTCTGCTGGTTGGATTAACTGCAGCCAAGACCTTAGTCATGCTGCACAATAAACCTCTCAT
TGGGGTCCATCACTTAGAAGGGCATATCCATGCCTCCTATCTTCAGAATCCTGATTTAGCCTCCCCTTTTCTTTGTTTAT
TGGTGTCCGGTGGCCATACCAGTTTGATTAAAGCTGAAGACTGTGGTCTATACCGCACCCTGGGTCAAACCCGAGATGAT
GCAGCGGGAGAAGCTTTTGACAAAGTGGCCCGTTTGCTAGATCTGGGATACCCTGGCGGCCCTGCCATTGATCGCATTGC
CAAGTTAGGCAATCCTAAAGCGTTTGCCCTCCCTGAGGGGAAAATTTCTCTACCAGAAGGTGGCTTTCATCCCTATGACA
CCAGCTTCAGTGGCTTGAAAACAGCCGTTCTCCGCTTAGTGGAATCTTTCCGACTGCGAGGGGAAGACGTGCCTGTCGCG
GATATTGCAGCCAGCTTCCAACAAACGGTGGCTCAAGCCTTGACTCGACGAGCCATCAAATGTGCCTTGGACTACGGCTT
ATCCACTATTGCTGTTGGCGGTGGCGTTGCCGCCAATAGTGCCTTACGCCAACAACTATTAACCGCCGCTGAAGACAAAA
AACTACAGGTCTTGTTTCCACCCTTATCTCTTTGTACGGACAATGCCGCGATGATCGCCTGTGCAGGCGCAGAACACTTG
GATCGAGGCCATACTTCAGCGCTGACCCTGGCAGCATTATCCCGCATGCCCATTTCTAAAGTGATGGAATTATACCCAGG
GTCATCCCCAATGCACCCTCCTTTGGAGCTTGACGCTGAATGA

Upstream 100 bases:

>100_bases
ACGCATAGACTTAAGAAGCAATCATACTCTTTGAGTGGGGTCTTGGTAAAGAATTGAGGCCCCTAAATACACGCATACAC
CATCAAAAAGTTACCAGTTT

Downstream 100 bases:

>100_bases
ATCTGATCGTAGTGGGGTCAATCGCTAGCCTAATCGCTGGGTTGGCAACAGGCATCGGTGCATTACCCGTATTATTCGTC
AAAACCCTGACGGATCGTTT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MATVLAIETSCDETAAAVVKKRHILSNIVASQIDIHRPYGGVVPEVASRHHVESINDVVSEALSQAQIDWPDIDGIAVTC
APGLVGALLVGLTAAKTLVMLHNKPLIGVHHLEGHIHASYLQNPDLASPFLCLLVSGGHTSLIKAEDCGLYRTLGQTRDD
AAGEAFDKVARLLDLGYPGGPAIDRIAKLGNPKAFALPEGKISLPEGGFHPYDTSFSGLKTAVLRLVESFRLRGEDVPVA
DIAASFQQTVAQALTRRAIKCALDYGLSTIAVGGGVAANSALRQQLLTAAEDKKLQVLFPPLSLCTDNAAMIACAGAEHL
DRGHTSALTLAALSRMPISKVMELYPGSSPMHPPLELDAE

Sequences:

>Translated_360_residues
MATVLAIETSCDETAAAVVKKRHILSNIVASQIDIHRPYGGVVPEVASRHHVESINDVVSEALSQAQIDWPDIDGIAVTC
APGLVGALLVGLTAAKTLVMLHNKPLIGVHHLEGHIHASYLQNPDLASPFLCLLVSGGHTSLIKAEDCGLYRTLGQTRDD
AAGEAFDKVARLLDLGYPGGPAIDRIAKLGNPKAFALPEGKISLPEGGFHPYDTSFSGLKTAVLRLVESFRLRGEDVPVA
DIAASFQQTVAQALTRRAIKCALDYGLSTIAVGGGVAANSALRQQLLTAAEDKKLQVLFPPLSLCTDNAAMIACAGAEHL
DRGHTSALTLAALSRMPISKVMELYPGSSPMHPPLELDAE
>Mature_359_residues
ATVLAIETSCDETAAAVVKKRHILSNIVASQIDIHRPYGGVVPEVASRHHVESINDVVSEALSQAQIDWPDIDGIAVTCA
PGLVGALLVGLTAAKTLVMLHNKPLIGVHHLEGHIHASYLQNPDLASPFLCLLVSGGHTSLIKAEDCGLYRTLGQTRDDA
AGEAFDKVARLLDLGYPGGPAIDRIAKLGNPKAFALPEGKISLPEGGFHPYDTSFSGLKTAVLRLVESFRLRGEDVPVAD
IAASFQQTVAQALTRRAIKCALDYGLSTIAVGGGVAANSALRQQLLTAAEDKKLQVLFPPLSLCTDNAAMIACAGAEHLD
RGHTSALTLAALSRMPISKVMELYPGSSPMHPPLELDAE

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=342, Percent_Identity=36.8421052631579, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI8923380, Length=337, Percent_Identity=31.1572700296736, Blast_Score=134, Evalue=9e-32,
Organism=Escherichia coli, GI1789445, Length=343, Percent_Identity=42.5655976676385, Blast_Score=244, Evalue=8e-66,
Organism=Caenorhabditis elegans, GI17557464, Length=338, Percent_Identity=36.3905325443787, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71995670, Length=334, Percent_Identity=31.1377245508982, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320099, Length=376, Percent_Identity=29.7872340425532, Blast_Score=123, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6322891, Length=318, Percent_Identity=29.559748427673, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20129063, Length=348, Percent_Identity=34.7701149425287, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI21357207, Length=356, Percent_Identity=30.0561797752809, Blast_Score=136, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_ACAM1 (B0C7S8)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001515783.1
- ProteinModelPortal:   B0C7S8
- SMR:   B0C7S8
- MEROPS:   M22.001
- GeneID:   5680261
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_1441
- HOGENOM:   HBG304663
- OMA:   PLYGVNH
- ProtClustDB:   PRK09604
- BioCyc:   AMAR329726:AM1_1441-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 37972; Mature: 37841

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVLAIETSCDETAAAVVKKRHILSNIVASQIDIHRPYGGVVPEVASRHHVESINDVVS
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
EALSQAQIDWPDIDGIAVTCAPGLVGALLVGLTAAKTLVMLHNKPLIGVHHLEGHIHASY
HHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCEEHHH
LQNPDLASPFLCLLVSGGHTSLIKAEDCGLYRTLGQTRDDAAGEAFDKVARLLDLGYPGG
CCCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
PAIDRIAKLGNPKAFALPEGKISLPEGGFHPYDTSFSGLKTAVLRLVESFRLRGEDVPVA
HHHHHHHHCCCCCEEECCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHH
DIAASFQQTVAQALTRRAIKCALDYGLSTIAVGGGVAANSALRQQLLTAAEDKKLQVLFP
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHHCCCCEEEEEC
PLSLCTDNAAMIACAGAEHLDRGHTSALTLAALSRMPISKVMELYPGSSPMHPPLELDAE
CHHHHCCCCEEEEECCHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATVLAIETSCDETAAAVVKKRHILSNIVASQIDIHRPYGGVVPEVASRHHVESINDVVS
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
EALSQAQIDWPDIDGIAVTCAPGLVGALLVGLTAAKTLVMLHNKPLIGVHHLEGHIHASY
HHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCEEHHH
LQNPDLASPFLCLLVSGGHTSLIKAEDCGLYRTLGQTRDDAAGEAFDKVARLLDLGYPGG
CCCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
PAIDRIAKLGNPKAFALPEGKISLPEGGFHPYDTSFSGLKTAVLRLVESFRLRGEDVPVA
HHHHHHHHCCCCCEEECCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHH
DIAASFQQTVAQALTRRAIKCALDYGLSTIAVGGGVAANSALRQQLLTAAEDKKLQVLFP
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHHCCCCEEEEEC
PLSLCTDNAAMIACAGAEHLDRGHTSALTLAALSRMPISKVMELYPGSSPMHPPLELDAE
CHHHHCCCCEEEEECCHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA