Click here to switch to the map view.

The map label for this gene is ppnK [H]

Identifier: 158334294

GI number: 158334294

Start: 1091573

End: 1092490

Strand: Direct

Name: ppnK [H]

Synonym: AM1_1113

Alternate gene names: 158334294

Gene position: 1091573-1092490 (Clockwise)

Preceding gene: 158334293

Following gene: 158334301

Centisome position: 16.78

GC content: 51.63

Gene sequence:

>918_bases
GTGCCGAAAGCTGGCATTATCTATAACGAACTCAAGCCGTTCGCTTGCCGAATTGCGACTGAACTCAAAGACAAGCTCCA
TGCTTGTGGTTGGCAAGTCTGCTTGGCGACAGGGGTTGGCGGCATCCTTGGATATTCACGCCCTGAACATCCCGTTTGCT
TCACGACGATTGATGAGTTGGTCCCTACTGGCTTTGATCAGGATGTCAAATTTGCCATCATTTTAGGTGGAGATGGCACT
GTTCTGTCTGCTTGCCGACAGCTAGCTCCATGTAATGTGCCAATGTTGACGGTAAACACGGGGCATATGGGGTTCCTAAC
GGAAACCTATGTCAATCAATTAGACGAAGTTCTGGATCTGTTGCTGCAAGATCAATTTTCCGTCGAAGAGCGAGCGACTC
TGACGGTACAGGTGATCACAGATGGAAAAGTGCTCTGGGAAGCCTTATCTCTCAATGAGATGTTGCTCCATAAAGAACCC
CTAGCCGGGATGTGCCACTTTGAAATAGCCGTCGGCGAGCATGCAGTGGTTGATATTGCTTCAGATGGCCTGCTGGTGTC
TACCCCCACAGGCTCTACGGCCTATGCTTTGGCTGCTGGAGGTCCAGTGATTGCCCCCGGCGTTCCGGTAATGCAGCTAA
TCCCGATTTGCCCCCACTCCCTGGCATCCAGAGCGCTGGTATTTGCTGATACCGAGCCTCTAGAGGTGGTTCCAGCCAAC
CAACAGCAGCTTGTCCTGGAAGTAGACGGAAACGCCGGATGCTATATTGCACCCGGCGATCGCGTACGTGTAATTAAGTC
ACCCTATTCAGCTCGCTTTATTCGGCTTGGATCCCCAGAGTTCTTTAAAATCCTGCGGGAGAAACTGGGTTGGGGATTAC
CCCACATCGCTAAGCCAACATCAGTAGAGCTGCCTTAG

Upstream 100 bases:

>100_bases
AGAAACTGAAGCAGCTCGAATACGAGAAGAACCAGAAACAATCTCGCAAACGGAGCCCCTTCAAAACTCCCAGTTCCTAA
CGATAGGTTGAACCTTGAGC

Downstream 100 bases:

>100_bases
GCTTTGTTAGGATGAGCAGCTACTGAGTTGATGCATATAAAGTCCAGGTGCATAGGCTTCAACAACTTCACCTGTCTTGG
CATCAGTGATCATTAAATAA

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 1 [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MPKAGIIYNELKPFACRIATELKDKLHACGWQVCLATGVGGILGYSRPEHPVCFTTIDELVPTGFDQDVKFAIILGGDGT
VLSACRQLAPCNVPMLTVNTGHMGFLTETYVNQLDEVLDLLLQDQFSVEERATLTVQVITDGKVLWEALSLNEMLLHKEP
LAGMCHFEIAVGEHAVVDIASDGLLVSTPTGSTAYALAAGGPVIAPGVPVMQLIPICPHSLASRALVFADTEPLEVVPAN
QQQLVLEVDGNAGCYIAPGDRVRVIKSPYSARFIRLGSPEFFKILREKLGWGLPHIAKPTSVELP

Sequences:

>Translated_305_residues
MPKAGIIYNELKPFACRIATELKDKLHACGWQVCLATGVGGILGYSRPEHPVCFTTIDELVPTGFDQDVKFAIILGGDGT
VLSACRQLAPCNVPMLTVNTGHMGFLTETYVNQLDEVLDLLLQDQFSVEERATLTVQVITDGKVLWEALSLNEMLLHKEP
LAGMCHFEIAVGEHAVVDIASDGLLVSTPTGSTAYALAAGGPVIAPGVPVMQLIPICPHSLASRALVFADTEPLEVVPAN
QQQLVLEVDGNAGCYIAPGDRVRVIKSPYSARFIRLGSPEFFKILREKLGWGLPHIAKPTSVELP
>Mature_304_residues
PKAGIIYNELKPFACRIATELKDKLHACGWQVCLATGVGGILGYSRPEHPVCFTTIDELVPTGFDQDVKFAIILGGDGTV
LSACRQLAPCNVPMLTVNTGHMGFLTETYVNQLDEVLDLLLQDQFSVEERATLTVQVITDGKVLWEALSLNEMLLHKEPL
AGMCHFEIAVGEHAVVDIASDGLLVSTPTGSTAYALAAGGPVIAPGVPVMQLIPICPHSLASRALVFADTEPLEVVPANQ
QQLVLEVDGNAGCYIAPGDRVRVIKSPYSARFIRLGSPEFFKILREKLGWGLPHIAKPTSVELP

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=257, Percent_Identity=28.0155642023346, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788968, Length=227, Percent_Identity=32.15859030837, Blast_Score=134, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6320794, Length=244, Percent_Identity=31.5573770491803, Blast_Score=119, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6322509, Length=253, Percent_Identity=29.2490118577075, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325068, Length=217, Percent_Identity=28.110599078341, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573828, Length=252, Percent_Identity=30.5555555555556, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573832, Length=221, Percent_Identity=32.1266968325792, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573830, Length=221, Percent_Identity=32.1266968325792, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI161077047, Length=221, Percent_Identity=32.1266968325792, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573826, Length=221, Percent_Identity=32.1266968325792, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129957, Length=277, Percent_Identity=27.0758122743682, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24653422, Length=277, Percent_Identity=27.0758122743682, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281363321, Length=277, Percent_Identity=27.0758122743682, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281363323, Length=277, Percent_Identity=27.0758122743682, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24653424, Length=277, Percent_Identity=27.0758122743682, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 32822; Mature: 32690

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKAGIIYNELKPFACRIATELKDKLHACGWQVCLATGVGGILGYSRPEHPVCFTTIDEL
CCCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEHHHH
VPTGFDQDVKFAIILGGDGTVLSACRQLAPCNVPMLTVNTGHMGFLTETYVNQLDEVLDL
CCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
LLQDQFSVEERATLTVQVITDGKVLWEALSLNEMLLHKEPLAGMCHFEIAVGEHAVVDIA
HHHCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEEEEEE
SDGLLVSTPTGSTAYALAAGGPVIAPGVPVMQLIPICPHSLASRALVFADTEPLEVVPAN
CCCEEEECCCCCCEEEEECCCCEECCCCCHHHHHCCCCHHHHCCEEEEECCCCCEEECCC
QQQLVLEVDGNAGCYIAPGDRVRVIKSPYSARFIRLGSPEFFKILREKLGWGLPHIAKPT
CCEEEEEECCCCCEEECCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCC
SVELP
CCCCC
>Mature Secondary Structure 
PKAGIIYNELKPFACRIATELKDKLHACGWQVCLATGVGGILGYSRPEHPVCFTTIDEL
CCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEHHHH
VPTGFDQDVKFAIILGGDGTVLSACRQLAPCNVPMLTVNTGHMGFLTETYVNQLDEVLDL
CCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
LLQDQFSVEERATLTVQVITDGKVLWEALSLNEMLLHKEPLAGMCHFEIAVGEHAVVDIA
HHHCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEEEEEE
SDGLLVSTPTGSTAYALAAGGPVIAPGVPVMQLIPICPHSLASRALVFADTEPLEVVPAN
CCCEEEECCCCCCEEEEECCCCEECCCCCHHHHHCCCCHHHHCCEEEEECCCCCEEECCC
QQQLVLEVDGNAGCYIAPGDRVRVIKSPYSARFIRLGSPEFFKILREKLGWGLPHIAKPT
CCEEEEEECCCCCEEECCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCC
SVELP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA