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The map label for this gene is guaA [H]

Identifier: 158334179

GI number: 158334179

Start: 967836

End: 968582

Strand: Direct

Name: guaA [H]

Synonym: AM1_0995

Alternate gene names: 158334179

Gene position: 967836-968582 (Clockwise)

Preceding gene: 158334175

Following gene: 158334180

Centisome position: 14.88

GC content: 46.59

Gene sequence:

>747_bases
ATGATTAAAGACCGCTCAAAACTCCATATCCTCTACATGCAAATTCGTGACGATCAAGTAACACGAATCGAAGAGCTACA
GGAATTTGCGCGTCATAGCCAACTGAATGAAAGCCAGTTCACCCCTCTCAACGTCTTTGATCAACCCGTCTTTTCCCCGG
ACTATGCCAATCGGTTTGACGCCGTATTTGTGGGGGGGTCAAGCGATGCTTCAGTCCTCAAGCCGGATCAATATCCTTTT
GTGGAGCCTGCCAAGCAATTACTCAAACATTGTGTCGATCACACTATTCCGGTGTTTGCTTCCTGCTTTGGTTTTCAGTT
AGGGGTAGAAGCCTTAGGTGGGAAAGTCATCCATGATGCCCAAAATATGGAAATGGGGATTTACCCAATGCAGCTCACTT
CAGCCGCTTGGGACGATCAATTGTTCGCTGATACCCCTGAACGATTTTTAGTCGTTTCGGGCCATAAAGAGCGGGCCTTT
AAACTGCCGCCTCATACTCAATTACTAGCATTTACAGAACGTTGTCCCTACCATGCCTTTAAAGTAATGGATAAACCGTT
CTACGGCTTTCAGTTTCATCCTGAGGTGGATCACCATGATTTAGCTGCCCGCATTACTCGCTATCAAGATCGGTATCTGG
AGACGGATGGGGCCTTACAAGCCATCCTTGATAACCTCCACCCCACACCAGAGTCAAATCGACTCATTCTCAAATTCGTT
GATCGGATTCTGCTGCAAAAAAGGTAA

Upstream 100 bases:

>100_bases
CTCTCTCTTGGACGTGAGCTAGAGACCAGTGGTGACTTAACTTCAGAAATTTATCGGATAACGAAATAATTTTTCCTTCA
ATGACCCATAACGACTTCTT

Downstream 100 bases:

>100_bases
AATCGGCACTTGCCCGATGCCTTAACTCTTAGCCCTTTTATCCCCAGTTAGGTAATTTCATGTCCACCCCTCTTACTGCC
GATCAAGTTAATCGAATTGT

Product: glutamine amidotransferase, class I

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MIKDRSKLHILYMQIRDDQVTRIEELQEFARHSQLNESQFTPLNVFDQPVFSPDYANRFDAVFVGGSSDASVLKPDQYPF
VEPAKQLLKHCVDHTIPVFASCFGFQLGVEALGGKVIHDAQNMEMGIYPMQLTSAAWDDQLFADTPERFLVVSGHKERAF
KLPPHTQLLAFTERCPYHAFKVMDKPFYGFQFHPEVDHHDLAARITRYQDRYLETDGALQAILDNLHPTPESNRLILKFV
DRILLQKR

Sequences:

>Translated_248_residues
MIKDRSKLHILYMQIRDDQVTRIEELQEFARHSQLNESQFTPLNVFDQPVFSPDYANRFDAVFVGGSSDASVLKPDQYPF
VEPAKQLLKHCVDHTIPVFASCFGFQLGVEALGGKVIHDAQNMEMGIYPMQLTSAAWDDQLFADTPERFLVVSGHKERAF
KLPPHTQLLAFTERCPYHAFKVMDKPFYGFQFHPEVDHHDLAARITRYQDRYLETDGALQAILDNLHPTPESNRLILKFV
DRILLQKR
>Mature_248_residues
MIKDRSKLHILYMQIRDDQVTRIEELQEFARHSQLNESQFTPLNVFDQPVFSPDYANRFDAVFVGGSSDASVLKPDQYPF
VEPAKQLLKHCVDHTIPVFASCFGFQLGVEALGGKVIHDAQNMEMGIYPMQLTSAAWDDQLFADTPERFLVVSGHKERAF
KLPPHTQLLAFTERCPYHAFKVMDKPFYGFQFHPEVDHHDLAARITRYQDRYLETDGALQAILDNLHPTPESNRLILKFV
DRILLQKR

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GMP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR004739
- InterPro:   IPR022955
- InterPro:   IPR022310
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00117 GATase; PF00958 GMP_synt_C; PF02540 NAD_synthase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 28649; Mature: 28649

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDRSKLHILYMQIRDDQVTRIEELQEFARHSQLNESQFTPLNVFDQPVFSPDYANRFD
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
AVFVGGSSDASVLKPDQYPFVEPAKQLLKHCVDHTIPVFASCFGFQLGVEALGGKVIHDA
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECC
QNMEMGIYPMQLTSAAWDDQLFADTPERFLVVSGHKERAFKLPPHTQLLAFTERCPYHAF
CCCCCCCEEHHHCCCCCCCCHHCCCCCEEEEEECCCCCEEECCCCHHHHHHHHHCCHHHH
KVMDKPFYGFQFHPEVDHHDLAARITRYQDRYLETDGALQAILDNLHPTPESNRLILKFV
HHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHH
DRILLQKR
HHHHHCCC
>Mature Secondary Structure
MIKDRSKLHILYMQIRDDQVTRIEELQEFARHSQLNESQFTPLNVFDQPVFSPDYANRFD
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
AVFVGGSSDASVLKPDQYPFVEPAKQLLKHCVDHTIPVFASCFGFQLGVEALGGKVIHDA
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECC
QNMEMGIYPMQLTSAAWDDQLFADTPERFLVVSGHKERAFKLPPHTQLLAFTERCPYHAF
CCCCCCCEEHHHCCCCCCCCHHCCCCCEEEEEECCCCCEEECCCCHHHHHHHHHCCHHHH
KVMDKPFYGFQFHPEVDHHDLAARITRYQDRYLETDGALQAILDNLHPTPESNRLILKFV
HHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHH
DRILLQKR
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]