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The map label for this gene is grxC [C]

Identifier: 158334008

GI number: 158334008

Start: 802742

End: 803059

Strand: Reverse

Name: grxC [C]

Synonym: AM1_0822

Alternate gene names: 158334008

Gene position: 803059-802742 (Counterclockwise)

Preceding gene: 158334009

Following gene: 158334006

Centisome position: 12.35

GC content: 45.91

Gene sequence:

>318_bases
ATGCCAAATTTCTTAAACAACCTTTTGGGACGCCATCCTGAGCGAGTCAAGGCCAACACCGAAATCTATACTTGGCAAAC
TTGTCCGTTTTGTATTCGAGCCAAATTATTGTTGTCTTGGAAAGGGGTGAAATACACCGAATACAAGATTGATGGAGATG
AGGCTGCACGGGCCAAAATGGCTGAACGGGCCAATAACCGCAGATCCGTTCCTCAAATCTTTATCAATAATCAGCATATT
GGTGGCTGTGATGACTTGTATCAGATGGACACGATGGGCCAGCTAGACGACCTACTCTCTCAACCTGCTGCGAGTTAG

Upstream 100 bases:

>100_bases
AGATGCCAATCGAGATTGTGCTTCAATCACTCTCGCAGATCAATCGGTTACGTCACAATAAAATAGTAAGTTCTTACCTG
TTGCCAATTAGGAATTTCCC

Downstream 100 bases:

>100_bases
AGTCTGGATCTATCTGGACCTATAGAAGAACTCCCAGAGCCGGCTCTGGGAGTTCGAAAAGCTTCTTTTGAAACTGCTAC
TTCCTCACATACTGAAGGGA

Product: glutaredoxin 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 104

Protein sequence:

>105_residues
MPNFLNNLLGRHPERVKANTEIYTWQTCPFCIRAKLLLSWKGVKYTEYKIDGDEAARAKMAERANNRRSVPQIFINNQHI
GGCDDLYQMDTMGQLDDLLSQPAAS

Sequences:

>Translated_105_residues
MPNFLNNLLGRHPERVKANTEIYTWQTCPFCIRAKLLLSWKGVKYTEYKIDGDEAARAKMAERANNRRSVPQIFINNQHI
GGCDDLYQMDTMGQLDDLLSQPAAS
>Mature_104_residues
PNFLNNLLGRHPERVKANTEIYTWQTCPFCIRAKLLLSWKGVKYTEYKIDGDEAARAKMAERANNRRSVPQIFINNQHIG
GCDDLYQMDTMGQLDDLLSQPAAS

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:
GO:0009055: Glutaredoxin 3
GO:0015035: Glutaredoxin 3
GO:0045454: Glutaredoxin 3

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=82, Percent_Identity=60.9756097560976, Blast_Score=104, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 12018; Mature: 11887

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNFLNNLLGRHPERVKANTEIYTWQTCPFCIRAKLLLSWKGVKYTEYKIDGDEAARAKM
CCHHHHHHHCCCCCCEECCCEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
AERANNRRSVPQIFINNQHIGGCDDLYQMDTMGQLDDLLSQPAAS
HHHHCCCCCCCEEEECCCCCCCCHHHHHHHCCHHHHHHHCCCCCC
>Mature Secondary Structure 
PNFLNNLLGRHPERVKANTEIYTWQTCPFCIRAKLLLSWKGVKYTEYKIDGDEAARAKM
CHHHHHHHCCCCCCEECCCEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
AERANNRRSVPQIFINNQHIGGCDDLYQMDTMGQLDDLLSQPAAS
HHHHCCCCCCCEEEECCCCCCCCHHHHHHHCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]