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The map label for this gene is cph2 [H]

Identifier: 158333756

GI number: 158333756

Start: 551988

End: 553100

Strand: Reverse

Name: cph2 [H]

Synonym: AM1_0564

Alternate gene names: 158333756

Gene position: 553100-551988 (Counterclockwise)

Preceding gene: 158333757

Following gene: 158333755

Centisome position: 8.5

GC content: 45.28

Gene sequence:

>1113_bases
ATGCAAGCTGCTCATCTCAGTATTCTAATGATCGATGATGACGAGCAGGATGTAGAAATTGTTCGGGAATTGCTGAGTAT
CAGCCATGATTTCCCTGTAGATCTTTTACACTGTTCCGATCTAGCGAGTGGGTTTGAGTTATTAGAGTCTGAGATTGAGA
TTGATCTTGTTCTATTGGATTTGTGTATTGCAGGAACTGTAGGGCTTGATTTATTCCACCAAGTCAATCGAGCGTTTCCT
TTAACTCCCGTAATTATATTGAGTGGCAATTCAGATGAAGCAGTCGCTCTGAAGGCAATGCAAGAAGGTGCCCAAGACTA
TTTAGTGAAAGGACGATTTACAAGTAGTCATTTACGTCGCTCTATTCAGTATGCCGTTGAACGCCAAAGCTTATTACTGG
AACTGGATGCAAAAAATCGAACCTTACAATCCCTGTCTGAACAGCTTGAACTTGCCAATCAGCAGTTGGAAGAACTGGTA
ACGATAGATAGCTTAACTCAAGTCAACAATCGTCGTTGCTTTGATGAGACCTTTTTATCGGAATGGAATAGATTGTGTCG
AGAGAATCATCCCTTATCCTTGATTATGTGCGATGTCGATCATTTCAAGGCGTTTAACGATACTTATGGTCACCAGGCTG
GAGATGTTTGTCTGCGGCAAGTCGCCCAAGCCATTGCTAAAGTAGCCAAACGACCTGCCGATTGTGTTGCTCGCTATGGG
GGGGAAGAGTTTGCCATTATCTTACCGAATACCGATTTAGATGGGGCAATCCAAGTTGCTGAGGCAATCCGCAGTACGAT
TCAGGAGCTTGCGATTCCTCACCAACACTCTTCGACAGGAAATAACGTTACTGCAAGCTTAGGGGTTGCCAGTCAGGTCC
CTGATGAGAATGTGGCCCCCTCAATTTTGATTGAAGCGGCCGATCGAGCTTTGTATGTGGCTAAGCAACAGGGGCGCGAT
CGCGTCCAGACTCATCAAAAAGATTGTGCTTCTTTGGAGTCTCGGCGAACATTGGAATTAGTCGGACGTTTACAGCAAGC
CCTCCATCAGCAAAAAGCAAAGCGGCGGGGTAAGCTACGTTTGAGACCTGGAGCACTGTTTACATCCCAATAG

Upstream 100 bases:

>100_bases
AGAGATAACGAAGGACTTATCTTCTCCGTATTAGTTCGGAAGGATAGTGATTTTTTGCCCAGAAGAACGTCTATTTTTTT
GACAAGGGGGCCCCTAAAAA

Downstream 100 bases:

>100_bases
CTCCAGCTCTAGTGGAAGACATTGCTTGTTCGAGAACGTTCCAAACCAATAGGTAAAGACTTATTTTCCACCTTCAGGGT
GGGAGTGTTTTCTCTGAACC

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MQAAHLSILMIDDDEQDVEIVRELLSISHDFPVDLLHCSDLASGFELLESEIEIDLVLLDLCIAGTVGLDLFHQVNRAFP
LTPVIILSGNSDEAVALKAMQEGAQDYLVKGRFTSSHLRRSIQYAVERQSLLLELDAKNRTLQSLSEQLELANQQLEELV
TIDSLTQVNNRRCFDETFLSEWNRLCRENHPLSLIMCDVDHFKAFNDTYGHQAGDVCLRQVAQAIAKVAKRPADCVARYG
GEEFAIILPNTDLDGAIQVAEAIRSTIQELAIPHQHSSTGNNVTASLGVASQVPDENVAPSILIEAADRALYVAKQQGRD
RVQTHQKDCASLESRRTLELVGRLQQALHQQKAKRRGKLRLRPGALFTSQ

Sequences:

>Translated_370_residues
MQAAHLSILMIDDDEQDVEIVRELLSISHDFPVDLLHCSDLASGFELLESEIEIDLVLLDLCIAGTVGLDLFHQVNRAFP
LTPVIILSGNSDEAVALKAMQEGAQDYLVKGRFTSSHLRRSIQYAVERQSLLLELDAKNRTLQSLSEQLELANQQLEELV
TIDSLTQVNNRRCFDETFLSEWNRLCRENHPLSLIMCDVDHFKAFNDTYGHQAGDVCLRQVAQAIAKVAKRPADCVARYG
GEEFAIILPNTDLDGAIQVAEAIRSTIQELAIPHQHSSTGNNVTASLGVASQVPDENVAPSILIEAADRALYVAKQQGRD
RVQTHQKDCASLESRRTLELVGRLQQALHQQKAKRRGKLRLRPGALFTSQ
>Mature_370_residues
MQAAHLSILMIDDDEQDVEIVRELLSISHDFPVDLLHCSDLASGFELLESEIEIDLVLLDLCIAGTVGLDLFHQVNRAFP
LTPVIILSGNSDEAVALKAMQEGAQDYLVKGRFTSSHLRRSIQYAVERQSLLLELDAKNRTLQSLSEQLELANQQLEELV
TIDSLTQVNNRRCFDETFLSEWNRLCRENHPLSLIMCDVDHFKAFNDTYGHQAGDVCLRQVAQAIAKVAKRPADCVARYG
GEEFAIILPNTDLDGAIQVAEAIRSTIQELAIPHQHSSTGNNVTASLGVASQVPDENVAPSILIEAADRALYVAKQQGRD
RVQTHQKDCASLESRRTLELVGRLQQALHQQKAKRRGKLRLRPGALFTSQ

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=185, Percent_Identity=35.6756756756757, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI87082007, Length=229, Percent_Identity=35.3711790393013, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=38.0368098159509, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=36.0248447204969, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87081881, Length=181, Percent_Identity=35.9116022099448, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786584, Length=170, Percent_Identity=32.3529411764706, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788381, Length=183, Percent_Identity=30.6010928961749, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787802, Length=169, Percent_Identity=33.7278106508876, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081974, Length=159, Percent_Identity=31.4465408805031, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081977, Length=206, Percent_Identity=30.5825242718447, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787541, Length=219, Percent_Identity=29.2237442922374, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787056, Length=167, Percent_Identity=32.9341317365269, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788085, Length=208, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788956, Length=201, Percent_Identity=28.3582089552239, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 41163; Mature: 41163

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAAHLSILMIDDDEQDVEIVRELLSISHDFPVDLLHCSDLASGFELLESEIEIDLVLLD
CCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCIAGTVGLDLFHQVNRAFPLTPVIILSGNSDEAVALKAMQEGAQDYLVKGRFTSSHLRR
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCHHHHHHCCCCCHHHHHH
SIQYAVERQSLLLELDAKNRTLQSLSEQLELANQQLEELVTIDSLTQVNNRRCFDETFLS
HHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EWNRLCRENHPLSLIMCDVDHFKAFNDTYGHQAGDVCLRQVAQAIAKVAKRPADCVARYG
HHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCC
GEEFAIILPNTDLDGAIQVAEAIRSTIQELAIPHQHSSTGNNVTASLGVASQVPDENVAP
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHCCCCCCCCH
SILIEAADRALYVAKQQGRDRVQTHQKDCASLESRRTLELVGRLQQALHQQKAKRRGKLR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LRPGALFTSQ
ECCCCCCCCC
>Mature Secondary Structure
MQAAHLSILMIDDDEQDVEIVRELLSISHDFPVDLLHCSDLASGFELLESEIEIDLVLLD
CCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCIAGTVGLDLFHQVNRAFPLTPVIILSGNSDEAVALKAMQEGAQDYLVKGRFTSSHLRR
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCHHHHHHCCCCCHHHHHH
SIQYAVERQSLLLELDAKNRTLQSLSEQLELANQQLEELVTIDSLTQVNNRRCFDETFLS
HHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EWNRLCRENHPLSLIMCDVDHFKAFNDTYGHQAGDVCLRQVAQAIAKVAKRPADCVARYG
HHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCC
GEEFAIILPNTDLDGAIQVAEAIRSTIQELAIPHQHSSTGNNVTASLGVASQVPDENVAP
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHCCCCCCCCH
SILIEAADRALYVAKQQGRDRVQTHQKDCASLESRRTLELVGRLQQALHQQKAKRRGKLR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LRPGALFTSQ
ECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]