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The map label for this gene is lss [H]

Identifier: 158333755

GI number: 158333755

Start: 550667

End: 551383

Strand: Reverse

Name: lss [H]

Synonym: AM1_0562

Alternate gene names: 158333755

Gene position: 551383-550667 (Counterclockwise)

Preceding gene: 158333756

Following gene: 158333750

Centisome position: 8.48

GC content: 50.35

Gene sequence:

>717_bases
ATGACTTCAGGGTTGGGACTCATATTAGTGCTATTAGCGATTTTCCATCCCTATAGCCCTTTTAAAACTCACTTGACCGG
CACAATGGGAGGTGCAGATATTGCTAAGGATGATCCCCCTATTGCCCAGCCTCCACAGGAAATTAAGCCGACAGCCAATC
TGAGGTTATTGACCTTGGCTCTCCATGAGCAGCCGACCGTTGACTCGCCTTTGGAAGGTTTTTGCCATCCGCTCTGGGGG
CAAGGATGGTTAAGTCAAGGGATACGAGGGGTCACCCACAATGGTCGGATGGAATATGCCTATGATTATGCAGCTGGGAT
TGGTACGCCAGTCTATGCGATGCGATCAGGGCGAGTCATCAGTATCCAAGATAAATACCCTGATCGTGGGGGCGGCAAAG
AACAAATTCATCGATTTAATCACGTCTGGTTGGAACATGATGGTGGGTACCGTTCTGCTTATGTTCACCTGCAACAAGGA
TTTCGCCACCGGGTGAACCTTAAAGTTGGGGATCAAGTTAAGGCCGGACAGATTATTGGCTATAGCGGTAACTCTGGCTG
GAGTAGTGGCCCACATCTCCATGTAGAGGTCCATCGTGCCGAAGAACCTTTTCAGTTCACCCAAACCGTCCCCTTTGCCA
TTGCTAGCTCCTGTAGTCTGGGGCGTCAGGCTACAGAACTCGCAACTAAATCGCCGACAGTTGTGGACTCGCCGTAA

Upstream 100 bases:

>100_bases
TCCTCAGCAACGTCCCCCTTCAATTTCACAACGTAATTTCGGTAACCAGAGGCCCCTGGTCTCTTTTCTCACCAGGATCC
ACCAGTCCCCCTATCTATGG

Downstream 100 bases:

>100_bases
CCACTGGGGTTTGGCTTTGGCTAATGGTGAGTATCTCTTGTCTTGCCCACTGATCAGCAGCCAGGATGTCTTCTAGGCTA
GGTTGCAAGGTGTTTTGGGA

Product: peptidase M23B

Products: NA

Alternate protein names: Glycyl-glycine endopeptidase [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTSGLGLILVLLAIFHPYSPFKTHLTGTMGGADIAKDDPPIAQPPQEIKPTANLRLLTLALHEQPTVDSPLEGFCHPLWG
QGWLSQGIRGVTHNGRMEYAYDYAAGIGTPVYAMRSGRVISIQDKYPDRGGGKEQIHRFNHVWLEHDGGYRSAYVHLQQG
FRHRVNLKVGDQVKAGQIIGYSGNSGWSSGPHLHVEVHRAEEPFQFTQTVPFAIASSCSLGRQATELATKSPTVVDSP

Sequences:

>Translated_238_residues
MTSGLGLILVLLAIFHPYSPFKTHLTGTMGGADIAKDDPPIAQPPQEIKPTANLRLLTLALHEQPTVDSPLEGFCHPLWG
QGWLSQGIRGVTHNGRMEYAYDYAAGIGTPVYAMRSGRVISIQDKYPDRGGGKEQIHRFNHVWLEHDGGYRSAYVHLQQG
FRHRVNLKVGDQVKAGQIIGYSGNSGWSSGPHLHVEVHRAEEPFQFTQTVPFAIASSCSLGRQATELATKSPTVVDSP
>Mature_237_residues
TSGLGLILVLLAIFHPYSPFKTHLTGTMGGADIAKDDPPIAQPPQEIKPTANLRLLTLALHEQPTVDSPLEGFCHPLWGQ
GWLSQGIRGVTHNGRMEYAYDYAAGIGTPVYAMRSGRVISIQDKYPDRGGGKEQIHRFNHVWLEHDGGYRSAYVHLQQGF
RHRVNLKVGDQVKAGQIIGYSGNSGWSSGPHLHVEVHRAEEPFQFTQTVPFAIASSCSLGRQATELATKSPTVVDSP

Specific function: Lyses staphylococcal cells by hydrolyzing the polyglycine interpeptide bridges of the peptidoglycan [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047
- InterPro:   IPR002886
- InterPro:   IPR003646
- InterPro:   IPR013667 [H]

Pfam domain/function: PF01551 Peptidase_M23; PF08460 SH3_5 [H]

EC number: =3.4.24.75 [H]

Molecular weight: Translated: 26059; Mature: 25928

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGLGLILVLLAIFHPYSPFKTHLTGTMGGADIAKDDPPIAQPPQEIKPTANLRLLTLA
CCCCHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCCCCCCCCCCHHCCCCCCEEEEEEE
LHEQPTVDSPLEGFCHPLWGQGWLSQGIRGVTHNGRMEYAYDYAAGIGTPVYAMRSGRVI
ECCCCCCCCCHHHHHCCCCCCHHHHHCCCCCCCCCCEEEEEEHHHCCCCCEEEECCCCEE
SIQDKYPDRGGGKEQIHRFNHVWLEHDGGYRSAYVHLQQGFRHRVNLKVGDQVKAGQIIG
EEECCCCCCCCCHHHHHHHHEEEEEECCCCCHHHHEEHHCCCEEECEEECCCCCCCEEEE
YSGNSGWSSGPHLHVEVHRAEEPFQFTQTVPFAIASSCSLGRQATELATKSPTVVDSP
ECCCCCCCCCCEEEEEEECCCCCCHHHHCCHHHHHHCCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TSGLGLILVLLAIFHPYSPFKTHLTGTMGGADIAKDDPPIAQPPQEIKPTANLRLLTLA
CCCHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCCCCCCCCCCHHCCCCCCEEEEEEE
LHEQPTVDSPLEGFCHPLWGQGWLSQGIRGVTHNGRMEYAYDYAAGIGTPVYAMRSGRVI
ECCCCCCCCCHHHHHCCCCCCHHHHHCCCCCCCCCCEEEEEEHHHCCCCCEEEECCCCEE
SIQDKYPDRGGGKEQIHRFNHVWLEHDGGYRSAYVHLQQGFRHRVNLKVGDQVKAGQIIG
EEECCCCCCCCCHHHHHHHHEEEEEECCCCCHHHHEEHHCCCEEECEEECCCCCCCEEEE
YSGNSGWSSGPHLHVEVHRAEEPFQFTQTVPFAIASSCSLGRQATELATKSPTVVDSP
ECCCCCCCCCCEEEEEEECCCCCCHHHHCCHHHHHHCCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3547405; 9106216 [H]