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The map label for this gene is nagJ [H]

Identifier: 158333535

GI number: 158333535

Start: 305599

End: 306675

Strand: Direct

Name: nagJ [H]

Synonym: AM1_0334

Alternate gene names: 158333535

Gene position: 305599-306675 (Clockwise)

Preceding gene: 158333534

Following gene: 158333539

Centisome position: 4.7

GC content: 46.15

Gene sequence:

>1077_bases
ATGGACATCCAGCAATCATGGGGATATGGCGTTATTGAAGGCTTCTTTGGTAAGCCTTGGCCTTGGCAAGCCCGATTAGA
TTACGCCAGTTTTCTCAAACAAAATGGATATCAGTTCTATATCTATGCCCCTAAAGCCGATCCCTATTTACGGATTCGAT
GGCAGGACGTTTGGCCAGAGACCACCTATGCAGAACTGAAACAGCTCGGGGAACGGTATCGCCAAGCGGGTATCGCCTGG
GGAATTGGCATCAATTTGTATGAAATCTTCTTTAATTACGATCAGCAAACGATTGAGCAGCTAAATACCAAAATTCGATA
TCTCAATCAGCTTCAGCCGGATATTTTGGCGATTTTGTTTGATGATATGCGAGGAGATTGCGATCGCATTGCCCAGATTC
AAGCTGAAATTACCCACCGAATTACTGAACTGAGTACAGCCAAGACCTTTATTATGTGTCCGACCTACTACAGCAGCAGT
CGAATTCTGGATCAATTATTTGGAGAACGCCCCGACGACTACTTAGAAACCTTGGGGCAGTTAATCGATCCACAGTTGCA
TATTTTTTGGACAGGGCCAGAGATTTGCTCAAACAGCTATCCCCTGGAACACCTGCAAGAGGTCAGCCAAAAGCTGGGGC
GAAAACCCTTTATCTGGGATAACTACCCGGTCAATGATAGTGCCAACATGTGTAACCATCTGCATCTCAGGGCTTTTGAA
AATCGGCCCTTTCAAATGGCCGACTGGATTTCAGGACATGCAGTTAATCCTATGAATCAAGCCTACCTTTCTCAAATTCC
GTTGCGAACTCTGCACTTAAGCTATCAACAACAAAACGATTATGATCCACCGCAAGCCATGCAGGAAGCCGCTACGTCCC
TCTGTGGCCCTACACTGGCCAAGAGTCTGATAGATCATCTCAGTCTATTGCAAGACCAGGGTTTAGAGCAGATGGGGCCA
ACCCAAAAAGCAGAGTTAATGACCCAATACCAACCCATGGGCACTAAATTCTCACAAGAAATTGTGGGGTGGTTACAAGG
AGACTATCCCTTCTCCACAGACTGTCTCACGATGTGA

Upstream 100 bases:

>100_bases
TAGAAATTCTGAGTGCAATAGTGTAATCTCTTTTTCTGAACGCTTTGAACTCTCTTCATCAAGAACCCAAGTTAACGTTG
CGATGGGCTCGGCAATCACT

Downstream 100 bases:

>100_bases
TCATCAAACCTGAAGGTTTCCTCAATCGAAGTCTATCGGTAATCGCTTTTTGCCCAAAGAATATAGACTACGCTCGTGAA
AGTAGAGATTCTAGACCGCA

Product: hyaluronidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; Beta-hexosaminidase; GH84; Hexosaminidase B; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MDIQQSWGYGVIEGFFGKPWPWQARLDYASFLKQNGYQFYIYAPKADPYLRIRWQDVWPETTYAELKQLGERYRQAGIAW
GIGINLYEIFFNYDQQTIEQLNTKIRYLNQLQPDILAILFDDMRGDCDRIAQIQAEITHRITELSTAKTFIMCPTYYSSS
RILDQLFGERPDDYLETLGQLIDPQLHIFWTGPEICSNSYPLEHLQEVSQKLGRKPFIWDNYPVNDSANMCNHLHLRAFE
NRPFQMADWISGHAVNPMNQAYLSQIPLRTLHLSYQQQNDYDPPQAMQEAATSLCGPTLAKSLIDHLSLLQDQGLEQMGP
TQKAELMTQYQPMGTKFSQEIVGWLQGDYPFSTDCLTM

Sequences:

>Translated_358_residues
MDIQQSWGYGVIEGFFGKPWPWQARLDYASFLKQNGYQFYIYAPKADPYLRIRWQDVWPETTYAELKQLGERYRQAGIAW
GIGINLYEIFFNYDQQTIEQLNTKIRYLNQLQPDILAILFDDMRGDCDRIAQIQAEITHRITELSTAKTFIMCPTYYSSS
RILDQLFGERPDDYLETLGQLIDPQLHIFWTGPEICSNSYPLEHLQEVSQKLGRKPFIWDNYPVNDSANMCNHLHLRAFE
NRPFQMADWISGHAVNPMNQAYLSQIPLRTLHLSYQQQNDYDPPQAMQEAATSLCGPTLAKSLIDHLSLLQDQGLEQMGP
TQKAELMTQYQPMGTKFSQEIVGWLQGDYPFSTDCLTM
>Mature_358_residues
MDIQQSWGYGVIEGFFGKPWPWQARLDYASFLKQNGYQFYIYAPKADPYLRIRWQDVWPETTYAELKQLGERYRQAGIAW
GIGINLYEIFFNYDQQTIEQLNTKIRYLNQLQPDILAILFDDMRGDCDRIAQIQAEITHRITELSTAKTFIMCPTYYSSS
RILDQLFGERPDDYLETLGQLIDPQLHIFWTGPEICSNSYPLEHLQEVSQKLGRKPFIWDNYPVNDSANMCNHLHLRAFE
NRPFQMADWISGHAVNPMNQAYLSQIPLRTLHLSYQQQNDYDPPQAMQEAATSLCGPTLAKSLIDHLSLLQDQGLEQMGP
TQKAELMTQYQPMGTKFSQEIVGWLQGDYPFSTDCLTM

Specific function: Biological function unknown. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 fibronectin type-III domain [H]

Homologues:

Organism=Homo sapiens, GI11024698, Length=277, Percent_Identity=28.5198555956679, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI215490056, Length=277, Percent_Identity=28.5198555956679, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193211002, Length=271, Percent_Identity=29.8892988929889, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193211004, Length=271, Percent_Identity=29.8892988929889, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24648670, Length=281, Percent_Identity=27.0462633451957, Blast_Score=112, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR011496
- InterPro:   IPR008965
- InterPro:   IPR000421
- InterPro:   IPR018452
- InterPro:   IPR008957
- InterPro:   IPR003961
- InterPro:   IPR008979
- InterPro:   IPR017853
- InterPro:   IPR013783 [H]

Pfam domain/function: PF00754 F5_F8_type_C; PF00041 fn3; PF02838 Glyco_hydro_20b; PF07555 NAGidase [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 41648; Mature: 41648

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIQQSWGYGVIEGFFGKPWPWQARLDYASFLKQNGYQFYIYAPKADPYLRIRWQDVWPE
CCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCC
TTYAELKQLGERYRQAGIAWGIGINLYEIFFNYDQQTIEQLNTKIRYLNQLQPDILAILF
CHHHHHHHHHHHHHHCCCCEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
DDMRGDCDRIAQIQAEITHRITELSTAKTFIMCPTYYSSSRILDQLFGERPDDYLETLGQ
HHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHH
LIDPQLHIFWTGPEICSNSYPLEHLQEVSQKLGRKPFIWDNYPVNDSANMCNHLHLRAFE
HHCCCEEEEECCHHHHCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHC
NRPFQMADWISGHAVNPMNQAYLSQIPLRTLHLSYQQQNDYDPPQAMQEAATSLCGPTLA
CCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHEEHHHHCCCCCCHHHHHHHHHHHCCHHHH
KSLIDHLSLLQDQGLEQMGPTQKAELMTQYQPMGTKFSQEIVGWLQGDYPFSTDCLTM
HHHHHHHHHHHHCCHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDIQQSWGYGVIEGFFGKPWPWQARLDYASFLKQNGYQFYIYAPKADPYLRIRWQDVWPE
CCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCC
TTYAELKQLGERYRQAGIAWGIGINLYEIFFNYDQQTIEQLNTKIRYLNQLQPDILAILF
CHHHHHHHHHHHHHHCCCCEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
DDMRGDCDRIAQIQAEITHRITELSTAKTFIMCPTYYSSSRILDQLFGERPDDYLETLGQ
HHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHH
LIDPQLHIFWTGPEICSNSYPLEHLQEVSQKLGRKPFIWDNYPVNDSANMCNHLHLRAFE
HHCCCEEEEECCHHHHCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHC
NRPFQMADWISGHAVNPMNQAYLSQIPLRTLHLSYQQQNDYDPPQAMQEAATSLCGPTLA
CCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHEEHHHHCCCCCCHHHHHHHHHHHCCHHHH
KSLIDHLSLLQDQGLEQMGPTQKAELMTQYQPMGTKFSQEIVGWLQGDYPFSTDCLTM
HHHHHHHHHHHHCCHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA