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The map label for this gene is degU [H]

Identifier: 158333495

GI number: 158333495

Start: 266426

End: 267103

Strand: Reverse

Name: degU [H]

Synonym: AM1_0267

Alternate gene names: 158333495

Gene position: 267103-266426 (Counterclockwise)

Preceding gene: 158333496

Following gene: 158333494

Centisome position: 4.11

GC content: 50.29

Gene sequence:

>678_bases
ATGAGAAGTACTCAGCCGCTATCCGTCGTTTTAGCGGATGATCAGCCCACCTTTCGCCAGGGATTGCGAACATTACTGGG
GTTTTACCAAGCCCAAGAATCGTTCCAGTTTCATATTGTGGGTGAGGCAGCCTCAGCCGATCAGGCGATTAGTTTGGCGT
TGGAACAACATCCAACCTTGCTGTTTCTAGACTTGGAACTGCCGAAAGATGACGGGGTCGCCGCTCTACAACATCTCAGA
CAGCAGAACTACACCGGCAAGATTCTCGTGATTTCAGCCCATCAGGAAGATGAATGGGTGTTTCGGGCCATGCGAGCGGG
GGCTGATGGTTATGTGTTTAAGTCTCAGTTAGCTATGAATTTGCATCAAGCCATTCAAACAGTGCTGAAGAATGAGGTGT
TTTTGCCACCGGATGCGGCAACTGGATTTTTCCGATCTTTTCATTTCTATGAAGGTCGGGCTGTTCAATCGGAGCAGACC
CTCCATCTGACGGCGCGGGAAAAGCAGGTGCTCCATTGGCTGGTTCAGGGGGCATCAAATCAAGCGATCGCAAATCACTT
ACACATTACGATCGCAACGGTGAAAGCCCACCTAACCGCCGTGTTTGAAAAGCTTGAGGTTAAAAGTCGCTCCCAGGCGA
TTGTCAAAGCCCTGAAGCTGGGTTTGGTTACCCCCTAA

Upstream 100 bases:

>100_bases
GGGGTCGGCTGTGGGCATCTAATTTGCCAGAAGGCGGTGCTCAATTTTCAATTAGTTTGCCACAAGAGTCCAACAATTAG
AATTATCGGGGGATTTGACC

Downstream 100 bases:

>100_bases
GGTTAGGTGAATGAGTAACTTTCTTGCGATCGCAACCGTAACTGCGGTCCTCCAACGGACCTTGCAAGCGGCCATTCAAG
AGGATGTAGAAGGAGCCAGG

Product: two-component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRSTQPLSVVLADDQPTFRQGLRTLLGFYQAQESFQFHIVGEAASADQAISLALEQHPTLLFLDLELPKDDGVAALQHLR
QQNYTGKILVISAHQEDEWVFRAMRAGADGYVFKSQLAMNLHQAIQTVLKNEVFLPPDAATGFFRSFHFYEGRAVQSEQT
LHLTAREKQVLHWLVQGASNQAIANHLHITIATVKAHLTAVFEKLEVKSRSQAIVKALKLGLVTP

Sequences:

>Translated_225_residues
MRSTQPLSVVLADDQPTFRQGLRTLLGFYQAQESFQFHIVGEAASADQAISLALEQHPTLLFLDLELPKDDGVAALQHLR
QQNYTGKILVISAHQEDEWVFRAMRAGADGYVFKSQLAMNLHQAIQTVLKNEVFLPPDAATGFFRSFHFYEGRAVQSEQT
LHLTAREKQVLHWLVQGASNQAIANHLHITIATVKAHLTAVFEKLEVKSRSQAIVKALKLGLVTP
>Mature_225_residues
MRSTQPLSVVLADDQPTFRQGLRTLLGFYQAQESFQFHIVGEAASADQAISLALEQHPTLLFLDLELPKDDGVAALQHLR
QQNYTGKILVISAHQEDEWVFRAMRAGADGYVFKSQLAMNLHQAIQTVLKNEVFLPPDAATGFFRSFHFYEGRAVQSEQT
LHLTAREKQVLHWLVQGASNQAIANHLHITIATVKAHLTAVFEKLEVKSRSQAIVKALKLGLVTP

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787473, Length=215, Percent_Identity=33.0232558139535, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788521, Length=216, Percent_Identity=32.4074074074074, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=28.780487804878, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1788712, Length=204, Percent_Identity=25, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788222, Length=205, Percent_Identity=23.4146341463415, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790102, Length=203, Percent_Identity=28.0788177339901, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25120; Mature: 25120

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTQPLSVVLADDQPTFRQGLRTLLGFYQAQESFQFHIVGEAASADQAISLALEQHPTL
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCEE
LFLDLELPKDDGVAALQHLRQQNYTGKILVISAHQEDEWVFRAMRAGADGYVFKSQLAMN
EEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHH
LHQAIQTVLKNEVFLPPDAATGFFRSFHFYEGRAVQSEQTLHLTAREKQVLHWLVQGASN
HHHHHHHHHHCCEECCCCCHHHHHHHHHHCCCCEECCCCEEEEEHHHHHHHHHHHHCCCC
QAIANHLHITIATVKAHLTAVFEKLEVKSRSQAIVKALKLGLVTP
CHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRSTQPLSVVLADDQPTFRQGLRTLLGFYQAQESFQFHIVGEAASADQAISLALEQHPTL
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCEE
LFLDLELPKDDGVAALQHLRQQNYTGKILVISAHQEDEWVFRAMRAGADGYVFKSQLAMN
EEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHH
LHQAIQTVLKNEVFLPPDAATGFFRSFHFYEGRAVQSEQTLHLTAREKQVLHWLVQGASN
HHHHHHHHHHCCEECCCCCHHHHHHHHHHCCCCEECCCCEEEEEHHHHHHHHHHHHCCCC
QAIANHLHITIATVKAHLTAVFEKLEVKSRSQAIVKALKLGLVTP
CHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]