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The map label for this gene is divL [H]

Identifier: 158333496

GI number: 158333496

Start: 267124

End: 268284

Strand: Reverse

Name: divL [H]

Synonym: AM1_0268

Alternate gene names: 158333496

Gene position: 268284-267124 (Counterclockwise)

Preceding gene: 158333497

Following gene: 158333495

Centisome position: 4.13

GC content: 46.6

Gene sequence:

>1161_bases
ATGCAGGTTGATCAACCCATAACTCTAAGCAATGGGTCTTTTGGTCTGGAAAAGCTTCCAGACCGTCGCCAATCCTTCTC
AACCATCGATTTAAATCAGCATTGCCAGGATTTTTTAGATTTAATTATTGATTATTTATCCCTCCCCATCGCTTGGATTT
TACGGCGGGGGTTGGGGCATCAGCTAAAGATTGGGATGGAGGTAGATGGTTGTGTACCGCAGGATATACTCACGGCTGCT
CACAACCGCACTTCTCTCAAGGATCTCCTAGCATCCCCGAATCTATTTTCTCAATTTGCTCTTGTATCTACTCAACCCGG
TTTACAACACTGGGTTTATCAAGACTGGCAAGTCTACAGTAGCTGCCTTTGTCAGCATCAGGGGCAGTACCTTTTATTTG
TCTCCCAGTCTCCGTTAACGACGTCGGAACGGCAATGGATAGAACGACAAATTCTGTTAATGAGTGACTATTTTGATCTG
CATTTGGCCTTTAATCAACAGCGAGCCGCGCTCTTAGCTAAACAACAGCATCTTCACCAGACCACTCATCAATTGGGGAC
GCCATTGTCACTCATCACCCTTTATGCTGACATGTTGCAAGTTAAAACAACCCCCCAAAACGGTCAGAACTATCTAGTAC
CGTTGCAACAGGCCGTTAAACAACTCCATCATCATCTCCAGGATTTGGTGGATGACGAAGAGGAGGACTCCCCCCTTGTT
GAACCATGTAATTTACATGATTTGGTGGCGGAGAATATCCGCGCTCTTCAACCCCACCTGCAAAGTCAGGGCATGGAGAT
TTGCTATCCACAAACGTCTGAGGTCGTTTGGATAGATCGTTGGCAAATGCTGCAAGTTTTCGACAATCTACTGAGTAATG
CTCTGCATTTTAGCCCCCAAGGAGGTCAGATTACGCTCACTTGGCAGCGATTCCAAACCGAAATCTTGATCGAGGTCAGG
GATCAAGGACCGGGATTATCATCGGAAGATTTGTGCTGCATGTTTTCCCCTTATTACTCACGACGGCAAGGAGGGCGAGG
TTTAGGATTAGCGATCGCACAGCAAATCGTTTGTCGTCATCGGGGTCGGCTGTGGGCATCTAATTTGCCAGAAGGCGGTG
CTCAATTTTCAATTAGTTTGCCACAAGAGTCCAACAATTAG

Upstream 100 bases:

>100_bases
CACTCCAGCCTTGCTTCAATTGTGAAATTTTCAATCATAAAACAAGCGCTCACTCGTTTTATTATTTTTTATAATTACTG
GATGGGGATGGGGGGCGGCT

Downstream 100 bases:

>100_bases
AATTATCGGGGGATTTGACCATGAGAAGTACTCAGCCGCTATCCGTCGTTTTAGCGGATGATCAGCCCACCTTTCGCCAG
GGATTGCGAACATTACTGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MQVDQPITLSNGSFGLEKLPDRRQSFSTIDLNQHCQDFLDLIIDYLSLPIAWILRRGLGHQLKIGMEVDGCVPQDILTAA
HNRTSLKDLLASPNLFSQFALVSTQPGLQHWVYQDWQVYSSCLCQHQGQYLLFVSQSPLTTSERQWIERQILLMSDYFDL
HLAFNQQRAALLAKQQHLHQTTHQLGTPLSLITLYADMLQVKTTPQNGQNYLVPLQQAVKQLHHHLQDLVDDEEEDSPLV
EPCNLHDLVAENIRALQPHLQSQGMEICYPQTSEVVWIDRWQMLQVFDNLLSNALHFSPQGGQITLTWQRFQTEILIEVR
DQGPGLSSEDLCCMFSPYYSRRQGGRGLGLAIAQQIVCRHRGRLWASNLPEGGAQFSISLPQESNN

Sequences:

>Translated_386_residues
MQVDQPITLSNGSFGLEKLPDRRQSFSTIDLNQHCQDFLDLIIDYLSLPIAWILRRGLGHQLKIGMEVDGCVPQDILTAA
HNRTSLKDLLASPNLFSQFALVSTQPGLQHWVYQDWQVYSSCLCQHQGQYLLFVSQSPLTTSERQWIERQILLMSDYFDL
HLAFNQQRAALLAKQQHLHQTTHQLGTPLSLITLYADMLQVKTTPQNGQNYLVPLQQAVKQLHHHLQDLVDDEEEDSPLV
EPCNLHDLVAENIRALQPHLQSQGMEICYPQTSEVVWIDRWQMLQVFDNLLSNALHFSPQGGQITLTWQRFQTEILIEVR
DQGPGLSSEDLCCMFSPYYSRRQGGRGLGLAIAQQIVCRHRGRLWASNLPEGGAQFSISLPQESNN
>Mature_386_residues
MQVDQPITLSNGSFGLEKLPDRRQSFSTIDLNQHCQDFLDLIIDYLSLPIAWILRRGLGHQLKIGMEVDGCVPQDILTAA
HNRTSLKDLLASPNLFSQFALVSTQPGLQHWVYQDWQVYSSCLCQHQGQYLLFVSQSPLTTSERQWIERQILLMSDYFDL
HLAFNQQRAALLAKQQHLHQTTHQLGTPLSLITLYADMLQVKTTPQNGQNYLVPLQQAVKQLHHHLQDLVDDEEEDSPLV
EPCNLHDLVAENIRALQPHLQSQGMEICYPQTSEVVWIDRWQMLQVFDNLLSNALHFSPQGGQITLTWQRFQTEILIEVR
DQGPGLSSEDLCCMFSPYYSRRQGGRGLGLAIAQQIVCRHRGRLWASNLPEGGAQFSISLPQESNN

Specific function: Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=240, Percent_Identity=28.75, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788549, Length=204, Percent_Identity=26.9607843137255, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=24.7899159663866, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI145693157, Length=222, Percent_Identity=25.6756756756757, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=26.1603375527426, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=25.8333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=114, Percent_Identity=35.9649122807018, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790436, Length=205, Percent_Identity=22.9268292682927, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=25.9574468085106, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=241, Percent_Identity=28.2157676348548, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786912, Length=262, Percent_Identity=24.0458015267176, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=242, Percent_Identity=26.4462809917355, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87081816, Length=220, Percent_Identity=26.8181818181818, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI48994928, Length=226, Percent_Identity=25.2212389380531, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44014; Mature: 44014

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVDQPITLSNGSFGLEKLPDRRQSFSTIDLNQHCQDFLDLIIDYLSLPIAWILRRGLGH
CCCCCCEEECCCCCCHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QLKIGMEVDGCVPQDILTAAHNRTSLKDLLASPNLFSQFALVSTQPGLQHWVYQDWQVYS
EEEECCEECCCCCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
SCLCQHQGQYLLFVSQSPLTTSERQWIERQILLMSDYFDLHLAFNQQRAALLAKQQHLHQ
HHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHH
TTHQLGTPLSLITLYADMLQVKTTPQNGQNYLVPLQQAVKQLHHHLQDLVDDEEEDSPLV
HHHHHCCCHHHHHHHHHHHHEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
EPCNLHDLVAENIRALQPHLQSQGMEICYPQTSEVVWIDRWQMLQVFDNLLSNALHFSPQ
CCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHEEECCC
GGQITLTWQRFQTEILIEVRDQGPGLSSEDLCCMFSPYYSRRQGGRGLGLAIAQQIVCRH
CCEEEEEHHHCCEEEEEEEECCCCCCCCCCEEEEECCHHHHCCCCCCHHHHHHHHHHHHH
RGRLWASNLPEGGAQFSISLPQESNN
CCCCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MQVDQPITLSNGSFGLEKLPDRRQSFSTIDLNQHCQDFLDLIIDYLSLPIAWILRRGLGH
CCCCCCEEECCCCCCHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QLKIGMEVDGCVPQDILTAAHNRTSLKDLLASPNLFSQFALVSTQPGLQHWVYQDWQVYS
EEEECCEECCCCCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
SCLCQHQGQYLLFVSQSPLTTSERQWIERQILLMSDYFDLHLAFNQQRAALLAKQQHLHQ
HHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHH
TTHQLGTPLSLITLYADMLQVKTTPQNGQNYLVPLQQAVKQLHHHLQDLVDDEEEDSPLV
HHHHHCCCHHHHHHHHHHHHEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
EPCNLHDLVAENIRALQPHLQSQGMEICYPQTSEVVWIDRWQMLQVFDNLLSNALHFSPQ
CCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHEEECCC
GGQITLTWQRFQTEILIEVRDQGPGLSSEDLCCMFSPYYSRRQGGRGLGLAIAQQIVCRH
CCEEEEEHHHCCEEEEEEEECCCCCCCCCCEEEEECCHHHHCCCCCCHHHHHHHHHHHHH
RGRLWASNLPEGGAQFSISLPQESNN
CCCCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10557274; 11259647 [H]