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The map label for this gene is crp [H]

Identifier: 158333439

GI number: 158333439

Start: 208739

End: 209440

Strand: Direct

Name: crp [H]

Synonym: AM1_0211

Alternate gene names: 158333439

Gene position: 208739-209440 (Clockwise)

Preceding gene: 158333436

Following gene: 158333440

Centisome position: 3.21

GC content: 48.01

Gene sequence:

>702_bases
ATGAAAGCCACTGTTGAACAACTTGCAGGACTCTCTCTTTTTGCAGAACTGCGTCCCCAAGATTTAGAAACGCTGCAACC
CCATACTCAGATTCGAACCTACCGAAAAGAAGAGATTCTTATTCATGAGGGAGATCTGATTCCTGAAAAACTGCATGTGT
TGTTCAAAGGGGTACTGCAAGTCGTTAAAAGTTCAGCAACGGGGAAGGAGACGATTTTGCGGCGGCTGAGGGCAGGTGAT
ATCTTTGCTGCTCCAGCTCTGTTTGGAGACGCATTAGCTCCAGCAACGGTCTTGGCAATTGAGGATTGCCAGGTATTAAC
CATTGATAGAGCAGACCTTTTGAGGGCGATTCAAGAAGCTCCAGAACTGGCGCTGAGCATCTTGGTGGTCTTTAACCAGC
GGCTCCAGCAGTTGCATAAGATGGTGCATGGGTTGGTTTCAGAGCGAGCAGTGGTGCGTTTGGCTCAGCTCATCCAATAT
TCAGCTCTACAGCATGGAACTAAGGTGACGGAGGCAGGTGAGCAGCTTCAGATCAAGTTGCCCTACTACCAAATGGCACG
GAGCATCGGGATTACTTATGAAGAATGTGCTCGCTTAATGAAAGGACTCCATGCAGTAGTGGCCTATCAAAGGGGTGGCA
AAATTGTCATTCTTGATCCGGAGGAATTGACAGCCATCGCTGAAGGGCAAAAAGAAATTTAG

Upstream 100 bases:

>100_bases
CCTACTGTTTTCTTGAAGTCTTTTGCTGTTCCGTACATACTCAATATGCTGAATCTTCATCTACATGTCTTTGAGGTAGC
TCAAAGAGCAGCCCTTTTAT

Downstream 100 bases:

>100_bases
CTTGTATGAGGTAGCTCATAGTTGTTCGTAGGCAATCTTGGCAGACTTAAACCTGTTCAAGTTACCGAGACGAAAATGAA
CTATGGCGCTACAAACAGAA

Product: cyclic nucleotide-binding domain-containing protein

Products: NA

Alternate protein names: cAMP receptor protein; cAMP regulatory protein [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKATVEQLAGLSLFAELRPQDLETLQPHTQIRTYRKEEILIHEGDLIPEKLHVLFKGVLQVVKSSATGKETILRRLRAGD
IFAAPALFGDALAPATVLAIEDCQVLTIDRADLLRAIQEAPELALSILVVFNQRLQQLHKMVHGLVSERAVVRLAQLIQY
SALQHGTKVTEAGEQLQIKLPYYQMARSIGITYEECARLMKGLHAVVAYQRGGKIVILDPEELTAIAEGQKEI

Sequences:

>Translated_233_residues
MKATVEQLAGLSLFAELRPQDLETLQPHTQIRTYRKEEILIHEGDLIPEKLHVLFKGVLQVVKSSATGKETILRRLRAGD
IFAAPALFGDALAPATVLAIEDCQVLTIDRADLLRAIQEAPELALSILVVFNQRLQQLHKMVHGLVSERAVVRLAQLIQY
SALQHGTKVTEAGEQLQIKLPYYQMARSIGITYEECARLMKGLHAVVAYQRGGKIVILDPEELTAIAEGQKEI
>Mature_233_residues
MKATVEQLAGLSLFAELRPQDLETLQPHTQIRTYRKEEILIHEGDLIPEKLHVLFKGVLQVVKSSATGKETILRRLRAGD
IFAAPALFGDALAPATVLAIEDCQVLTIDRADLLRAIQEAPELALSILVVFNQRLQQLHKMVHGLVSERAVVRLAQLIQY
SALQHGTKVTEAGEQLQIKLPYYQMARSIGITYEECARLMKGLHAVVAYQRGGKIVILDPEELTAIAEGQKEI

Specific function: This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR018488
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25889; Mature: 25889

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKATVEQLAGLSLFAELRPQDLETLQPHTQIRTYRKEEILIHEGDLIPEKLHVLFKGVLQ
CCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
VVKSSATGKETILRRLRAGDIFAAPALFGDALAPATVLAIEDCQVLTIDRADLLRAIQEA
HHHCCCCCHHHHHHHHHCCCCEEHHHHHHHHHCCHHEEEECCCEEEEECHHHHHHHHHHH
PELALSILVVFNQRLQQLHKMVHGLVSERAVVRLAQLIQYSALQHGTKVTEAGEQLQIKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEC
PYYQMARSIGITYEECARLMKGLHAVVAYQRGGKIVILDPEELTAIAEGQKEI
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCC
>Mature Secondary Structure
MKATVEQLAGLSLFAELRPQDLETLQPHTQIRTYRKEEILIHEGDLIPEKLHVLFKGVLQ
CCCHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
VVKSSATGKETILRRLRAGDIFAAPALFGDALAPATVLAIEDCQVLTIDRADLLRAIQEA
HHHCCCCCHHHHHHHHHCCCCEEHHHHHHHHHCCHHEEEECCCEEEEECHHHHHHHHHHH
PELALSILVVFNQRLQQLHKMVHGLVSERAVVRLAQLIQYSALQHGTKVTEAGEQLQIKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEC
PYYQMARSIGITYEECARLMKGLHAVVAYQRGGKIVILDPEELTAIAEGQKEI
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]