Click here to switch to the map view.

The map label for this gene is hmp [H]

Identifier: 158333440

GI number: 158333440

Start: 209523

End: 209969

Strand: Direct

Name: hmp [H]

Synonym: AM1_0212

Alternate gene names: 158333440

Gene position: 209523-209969 (Clockwise)

Preceding gene: 158333439

Following gene: 158333441

Centisome position: 3.22

GC content: 46.53

Gene sequence:

>447_bases
ATGGCGCTACAAACAGAACTTCTGACAAATAGCTTTGACCTGCTTCGAGAGAATGAAGCAGAATTCACCCAAGTGTTTTA
CGGCACATTATTTACGGACTACCCACAGGTGAAACCGCTGTTCTCCAACACTCATATGGATGAACAGGCCAAGAAATTAT
TTGCTTCTCTACTATTAGTGGTAAACAACCTGACAAAGCCCGATGCGCTTTCCTCAGCTCTGAAAGGTTTAGGCACTCGA
CATGTGAAGTATGGCGTTCTACCCGAACATTACCCCCTGGTTGGTAGCACCCTCCTCAAATCAATGGCAGCGACTCTCAA
AGATCAGTGGACTCCAGATATTGAGGCAGCCTGGACTGATGCCTATGGGGCGATCACTGAAATCATGCTGGAGGGGACGG
ATTACCCCGAAGAAGTATTGATCTCTGAAAGTATGTCAGCAACTTAA

Upstream 100 bases:

>100_bases
GGGCAAAAAGAAATTTAGCTTGTATGAGGTAGCTCATAGTTGTTCGTAGGCAATCTTGGCAGACTTAAACCTGTTCAAGT
TACCGAGACGAAAATGAACT

Downstream 100 bases:

>100_bases
AAGAACTATGAATCAGCGCTTTCAATCGCAACCCTATAAGAGTCTTTGCTTAGCAACAATTGCCTTTGCGATCTCATTTG
CCAGTTGGGGGGTGATCGCT

Product: globin domain-containing protein

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MALQTELLTNSFDLLRENEAEFTQVFYGTLFTDYPQVKPLFSNTHMDEQAKKLFASLLLVVNNLTKPDALSSALKGLGTR
HVKYGVLPEHYPLVGSTLLKSMAATLKDQWTPDIEAAWTDAYGAITEIMLEGTDYPEEVLISESMSAT

Sequences:

>Translated_148_residues
MALQTELLTNSFDLLRENEAEFTQVFYGTLFTDYPQVKPLFSNTHMDEQAKKLFASLLLVVNNLTKPDALSSALKGLGTR
HVKYGVLPEHYPLVGSTLLKSMAATLKDQWTPDIEAAWTDAYGAITEIMLEGTDYPEEVLISESMSAT
>Mature_147_residues
ALQTELLTNSFDLLRENEAEFTQVFYGTLFTDYPQVKPLFSNTHMDEQAKKLFASLLLVVNNLTKPDALSSALKGLGTRH
VKYGVLPEHYPLVGSTLLKSMAATLKDQWTPDIEAAWTDAYGAITEIMLEGTDYPEEVLISESMSAT

Specific function: Possesses Dihydropteridine Reductase Activity. Also Has Nitric Oxide Dioxygenase Activity. Seems To Reduces The Complexed Fe(3+) Iron Of Siderophores To Fe(2+), Thus Releasing It From The Chelator. [C]

COG id: COG1017

COG function: function code C; Hemoglobin-like flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=121, Percent_Identity=31.404958677686, Blast_Score=62, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321673, Length=126, Percent_Identity=29.3650793650794, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 16465; Mature: 16334

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQTELLTNSFDLLRENEAEFTQVFYGTLFTDYPQVKPLFSNTHMDEQAKKLFASLLLV
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHHH
VNNLTKPDALSSALKGLGTRHVKYGVLPEHYPLVGSTLLKSMAATLKDQWTPDIEAAWTD
HHCCCCCHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AYGAITEIMLEGTDYPEEVLISESMSAT
HHHHHHHHHHCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
ALQTELLTNSFDLLRENEAEFTQVFYGTLFTDYPQVKPLFSNTHMDEQAKKLFASLLLV
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHHH
VNNLTKPDALSSALKGLGTRHVKYGVLPEHYPLVGSTLLKSMAATLKDQWTPDIEAAWTD
HHCCCCCHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AYGAITEIMLEGTDYPEEVLISESMSAT
HHHHHHHHHHCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]