Click here to switch to the map view.

The map label for this gene is muT4 [H]

Identifier: 158319039

GI number: 158319039

Start: 8952153

End: 8952578

Strand: Direct

Name: muT4 [H]

Synonym: Franean1_7322

Alternate gene names: 158319039

Gene position: 8952153-8952578 (Clockwise)

Preceding gene: 158319037

Following gene: 158319040

Centisome position: 99.67

GC content: 71.83

Gene sequence:

>426_bases
GTGGAGGAGACCTCGGCCGGGGGCCTCGTGCTCGACACCGCGTCCGCCGCCGCGAACGCGGCGCTGATCGCCCGCAGGGA
CAAGCGTGGCCGGCTGTTGTGGTCGCTGCCGAAGGGTCATGTCGAGTGCGATGAGACCACGGAGGAGGCCGCCGTCCGAG
AGGTCGCCGAGGAGACCGGTGTGACCGGAGCGGTTCTGGGCCCGCTGGGCACGATCGACTTCTGGTTCGTCGCCGGCGAG
GCTCGCGTGCACAAGACCGTCCACCACTTCCTCCTGCTCCGGACGTCGGGCGACCTCTCCGACGACGACGTCGAGGTCGC
GGAGGTCGCGTGGGTCCCGCTGCCCGAGGTGGCGCGACGGCTCGCGTACGCCGACGAACGACGGCTGCTCGACGGGGTGC
CGACGATCCTCGCCGACGCCTCGTGA

Upstream 100 bases:

>100_bases
GAACGAGCGGGACACACAACGGGGCTGTTTCGGCTGGTGCTCGTACGATCAGTCCATGCCCTCCCCGCCCAGGACGCCCG
GCCGCAGGCCGTTGCGCAGG

Downstream 100 bases:

>100_bases
CCGGCCGTAACCCGTTCCGCCGGCACCGGCTGGCGGCCGCGGCGCTGCTCGGGACCGTCGCGTTGGTCTGGCCCGGGGCC
GATGTGGGCCTGGCGGCGGC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MEETSAGGLVLDTASAAANAALIARRDKRGRLLWSLPKGHVECDETTEEAAVREVAEETGVTGAVLGPLGTIDFWFVAGE
ARVHKTVHHFLLLRTSGDLSDDDVEVAEVAWVPLPEVARRLAYADERRLLDGVPTILADAS

Sequences:

>Translated_141_residues
MEETSAGGLVLDTASAAANAALIARRDKRGRLLWSLPKGHVECDETTEEAAVREVAEETGVTGAVLGPLGTIDFWFVAGE
ARVHKTVHHFLLLRTSGDLSDDDVEVAEVAWVPLPEVARRLAYADERRLLDGVPTILADAS
>Mature_141_residues
MEETSAGGLVLDTASAAANAALIARRDKRGRLLWSLPKGHVECDETTEEAAVREVAEETGVTGAVLGPLGTIDFWFVAGE
ARVHKTVHHFLLLRTSGDLSDDDVEVAEVAWVPLPEVARRLAYADERRLLDGVPTILADAS

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. In vitro has dATPase rather than 8-oxo-dGTPase activity [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.-.- [C]

Molecular weight: Translated: 15144; Mature: 15144

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEETSAGGLVLDTASAAANAALIARRDKRGRLLWSLPKGHVECDETTEEAAVREVAEETG
CCCCCCCCEEEECCHHHHCCCEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHC
VTGAVLGPLGTIDFWFVAGEARVHKTVHHFLLLRTSGDLSDDDVEVAEVAWVPLPEVARR
CCEEEECCCCCEEEEEEECCHHHHHHHHHHEEEECCCCCCCCCCEEEHEECCCCHHHHHH
LAYADERRLLDGVPTILADAS
HHHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure
MEETSAGGLVLDTASAAANAALIARRDKRGRLLWSLPKGHVECDETTEEAAVREVAEETG
CCCCCCCCEEEECCHHHHCCCEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHC
VTGAVLGPLGTIDFWFVAGEARVHKTVHHFLLLRTSGDLSDDDVEVAEVAWVPLPEVARR
CCEEEECCCCCEEEEEEECCHHHHHHHHHHEEEECCCCCCCCCCEEEHEECCCCHHHHHH
LAYADERRLLDGVPTILADAS
HHHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]