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The map label for this gene is pgi [H]

Identifier: 158319003

GI number: 158319003

Start: 8898114

End: 8899826

Strand: Reverse

Name: pgi [H]

Synonym: Franean1_7286

Alternate gene names: 158319003

Gene position: 8899826-8898114 (Counterclockwise)

Preceding gene: 158319007

Following gene: 158319002

Centisome position: 99.08

GC content: 69.53

Gene sequence:

>1713_bases
GTGGGCGCGCGGACGGCGCGGCACACGACAGCACTCCTCCGAGGAAGGGCCTCCAACGCCATGGCGAACACCGAGTCCAC
CGCCCTCGCCGCTGGAACGGTCGTCGACCGGACCCCGGAATGGGCCGCGCTGGCCGCGCACCACGCGGAGATCTCCGGGG
TGACCCTGCGGAAGCTCTTCGCCGATGATCCGGGCCGCGCCGATTCGTTCACCGTCGAGGCGGACGGCCTTCGGCTCGAC
TACTCCAAGAACATCGTCACGGCCCGGACGGTCGAACTGCTGCTCGCGCTGGCGCGTCGCGCCGGCCTCGGCGCGCGCAT
CGAGGCGATGTTCGGCGGCGAGCGCATCAACGTCACCGAGAACCGGCCGGTGCTGCACGTGGCGCTGCGCACGCCGCTCG
GAACCAGCATCCACGTGGACGGCGTCGACGTGGTGCCGGAGGTGCACGCCGTGCTCGACCGGATGTCGGCGTTCTGCGAC
CGGGTCCGCTCCGGGGTGTGGACGGGGGCGACCGGCGAGCACATCACGACCGTCGTCAACATCGGCATCGGCGGCTCCGA
CCTGGGGCCCGCGATGGCCTACCAGGCGCTGCGGGACTACTCCGACCGCTCGATCGCCGTCCGGTTCGTCTCGAACGTCG
ACCCGACGGACATCTGGGAAGCCACCCACGACCTCGATCCGGCCAGGACGCTCTTCATCGTCGCGTCGAAGACGTTCACC
ACGCTGGAGACGCTCGCGAACGCCCGCGCCGCGCGGGCCTGGCTCACCGCCGCGCTCGGCCAGGACGCCGTCGCGCACCA
TTTCGTTGCCGTGTCAACGAATGCGGAGAAGGTGGCCGAGTTCGGCATCGACACGGCCAACATGTTCGAGTTCTGGGACT
GGGTGGGCGGCCGGTACTCGATGGACTCCGCCATCGGTCTCGCTCTGATGGTCGCGATCGGCCCGCACCACTTCCGGGAG
ATGCTGGCCGGATTCCACGCGATGGATGTTCATTTCCGGAACACCCCGTTCGAGCGGAACCTGCCGGTTCTGCTCGGCGT
GCTCGGGCTGTGGTACCGGGACTTCTTCGGCGCCCAGAGCCACGCCGTGCTCCCCTACAGCCAGTACCTGGACCGCTTCC
CGGCGTACCTGCAGCAGCTGGACATGGAGAGTAACGGCAAGTCAGTTGATCTGGCCGGCCGGCCCGTACCGGTGCCGACC
GGCCCGGTGGTGTGGGGCACCCCGGGAACCAACGGTCAGCACGCCTACTTCCAGCTCCTGCACCAGGGGACGACGGTCGT
CCCGGCCGACTTCATCGGCTTCCTCGCGCCCAACCACCCAGGTGTCGGCGACGTCGACCAGCACGTCCTGCTGATGGCCA
ACTTCTTCGCTCAGACGGAGGCCCTCGCCTTCGGCAGGACGGCGGAGGAGGTCGCGGCCGAGGGGGTGGACGCCGCCCTC
GTCCCGCACCGGACGTTCGCCGGAAACCGTCCGACGAACACCCTGCTGGCGCCGAAGCTGACGCCCTTCGCCCTGGGCCA
GCTGGTCGCCCTCTACGAGCACAAGGTGTTCACGCAGGGCGTCGTGTGGGGGGTGAACAGCTACGACCAGTGGGGCGTGG
AGCTGGGCAAGGTGCTGGCCGGACGGATCATCCCCGAGCTGGCCGACCCGTCGGCGCCCCCGCGGCACGACAGCTCCACC
AACGCGCTGATCAACCTGTTCCGGTCGGTCTGA

Upstream 100 bases:

>100_bases
ACGGCCTGTTCCCCCACATTCCGCCCCTCGCAGGGACCCGACGGGCGCGTCAGATGCGCGACTGCACCATGCTGGTCGTC
GTCGACAGGTGTTCGGCCGT

Downstream 100 bases:

>100_bases
GCCGCGACCGCCCGGTCCAGTCCGGTTACGGGCTGGGCTGGGCTGGGCGTCGTCAATTAGTCATCGAGGTTTAACGATTC
CTTGATCTATGTTACTCTCT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MGARTARHTTALLRGRASNAMANTESTALAAGTVVDRTPEWAALAAHHAEISGVTLRKLFADDPGRADSFTVEADGLRLD
YSKNIVTARTVELLLALARRAGLGARIEAMFGGERINVTENRPVLHVALRTPLGTSIHVDGVDVVPEVHAVLDRMSAFCD
RVRSGVWTGATGEHITTVVNIGIGGSDLGPAMAYQALRDYSDRSIAVRFVSNVDPTDIWEATHDLDPARTLFIVASKTFT
TLETLANARAARAWLTAALGQDAVAHHFVAVSTNAEKVAEFGIDTANMFEFWDWVGGRYSMDSAIGLALMVAIGPHHFRE
MLAGFHAMDVHFRNTPFERNLPVLLGVLGLWYRDFFGAQSHAVLPYSQYLDRFPAYLQQLDMESNGKSVDLAGRPVPVPT
GPVVWGTPGTNGQHAYFQLLHQGTTVVPADFIGFLAPNHPGVGDVDQHVLLMANFFAQTEALAFGRTAEEVAAEGVDAAL
VPHRTFAGNRPTNTLLAPKLTPFALGQLVALYEHKVFTQGVVWGVNSYDQWGVELGKVLAGRIIPELADPSAPPRHDSST
NALINLFRSV

Sequences:

>Translated_570_residues
MGARTARHTTALLRGRASNAMANTESTALAAGTVVDRTPEWAALAAHHAEISGVTLRKLFADDPGRADSFTVEADGLRLD
YSKNIVTARTVELLLALARRAGLGARIEAMFGGERINVTENRPVLHVALRTPLGTSIHVDGVDVVPEVHAVLDRMSAFCD
RVRSGVWTGATGEHITTVVNIGIGGSDLGPAMAYQALRDYSDRSIAVRFVSNVDPTDIWEATHDLDPARTLFIVASKTFT
TLETLANARAARAWLTAALGQDAVAHHFVAVSTNAEKVAEFGIDTANMFEFWDWVGGRYSMDSAIGLALMVAIGPHHFRE
MLAGFHAMDVHFRNTPFERNLPVLLGVLGLWYRDFFGAQSHAVLPYSQYLDRFPAYLQQLDMESNGKSVDLAGRPVPVPT
GPVVWGTPGTNGQHAYFQLLHQGTTVVPADFIGFLAPNHPGVGDVDQHVLLMANFFAQTEALAFGRTAEEVAAEGVDAAL
VPHRTFAGNRPTNTLLAPKLTPFALGQLVALYEHKVFTQGVVWGVNSYDQWGVELGKVLAGRIIPELADPSAPPRHDSST
NALINLFRSV
>Mature_569_residues
GARTARHTTALLRGRASNAMANTESTALAAGTVVDRTPEWAALAAHHAEISGVTLRKLFADDPGRADSFTVEADGLRLDY
SKNIVTARTVELLLALARRAGLGARIEAMFGGERINVTENRPVLHVALRTPLGTSIHVDGVDVVPEVHAVLDRMSAFCDR
VRSGVWTGATGEHITTVVNIGIGGSDLGPAMAYQALRDYSDRSIAVRFVSNVDPTDIWEATHDLDPARTLFIVASKTFTT
LETLANARAARAWLTAALGQDAVAHHFVAVSTNAEKVAEFGIDTANMFEFWDWVGGRYSMDSAIGLALMVAIGPHHFREM
LAGFHAMDVHFRNTPFERNLPVLLGVLGLWYRDFFGAQSHAVLPYSQYLDRFPAYLQQLDMESNGKSVDLAGRPVPVPTG
PVVWGTPGTNGQHAYFQLLHQGTTVVPADFIGFLAPNHPGVGDVDQHVLLMANFFAQTEALAFGRTAEEVAAEGVDAALV
PHRTFAGNRPTNTLLAPKLTPFALGQLVALYEHKVFTQGVVWGVNSYDQWGVELGKVLAGRIIPELADPSAPPRHDSSTN
ALINLFRSV

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=547, Percent_Identity=52.8336380255942, Blast_Score=574, Evalue=1e-164,
Organism=Homo sapiens, GI296080693, Length=559, Percent_Identity=48.8372093023256, Blast_Score=518, Evalue=1e-147,
Organism=Escherichia coli, GI1790457, Length=543, Percent_Identity=55.4327808471455, Blast_Score=595, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI71996703, Length=527, Percent_Identity=52.1821631878558, Blast_Score=542, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI71996708, Length=527, Percent_Identity=52.1821631878558, Blast_Score=542, Evalue=1e-154,
Organism=Saccharomyces cerevisiae, GI6319673, Length=556, Percent_Identity=48.9208633093525, Blast_Score=531, Evalue=1e-152,
Organism=Drosophila melanogaster, GI24651916, Length=530, Percent_Identity=51.8867924528302, Blast_Score=551, Evalue=1e-157,
Organism=Drosophila melanogaster, GI24651914, Length=530, Percent_Identity=51.8867924528302, Blast_Score=551, Evalue=1e-157,
Organism=Drosophila melanogaster, GI17737445, Length=530, Percent_Identity=51.8867924528302, Blast_Score=551, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 61619; Mature: 61487

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGARTARHTTALLRGRASNAMANTESTALAAGTVVDRTPEWAALAAHHAEISGVTLRKLF
CCCCHHHHHHHHHHCCCCCCCCCCCCHHEEECCHHCCCCCHHHHHHHHHHCCCHHHHHHH
ADDPGRADSFTVEADGLRLDYSKNIVTARTVELLLALARRAGLGARIEAMFGGERINVTE
CCCCCCCCCEEEEECCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEC
NRPVLHVALRTPLGTSIHVDGVDVVPEVHAVLDRMSAFCDRVRSGVWTGATGEHITTVVN
CCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
IGIGGSDLGPAMAYQALRDYSDRSIAVRFVSNVDPTDIWEATHDLDPARTLFIVASKTFT
ECCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEEEECCHHH
TLETLANARAARAWLTAALGQDAVAHHFVAVSTNAEKVAEFGIDTANMFEFWDWVGGRYS
HHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEECCHHHHHHHCCCHHHHHHHHHHCCCCCC
MDSAIGLALMVAIGPHHFREMLAGFHAMDVHFRNTPFERNLPVLLGVLGLWYRDFFGAQS
CHHHHHHHHHHHHCHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC
HAVLPYSQYLDRFPAYLQQLDMESNGKSVDLAGRPVPVPTGPVVWGTPGTNGQHAYFQLL
CEECCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCHHHHHHH
HQGTTVVPADFIGFLAPNHPGVGDVDQHVLLMANFFAQTEALAFGRTAEEVAAEGVDAAL
HCCCEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEE
VPHRTFAGNRPTNTLLAPKLTPFALGQLVALYEHKVFTQGVVWGVNSYDQWGVELGKVLA
CCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHH
GRIIPELADPSAPPRHDSSTNALINLFRSV
HHHHHHHCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
GARTARHTTALLRGRASNAMANTESTALAAGTVVDRTPEWAALAAHHAEISGVTLRKLF
CCCHHHHHHHHHHCCCCCCCCCCCCHHEEECCHHCCCCCHHHHHHHHHHCCCHHHHHHH
ADDPGRADSFTVEADGLRLDYSKNIVTARTVELLLALARRAGLGARIEAMFGGERINVTE
CCCCCCCCCEEEEECCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEC
NRPVLHVALRTPLGTSIHVDGVDVVPEVHAVLDRMSAFCDRVRSGVWTGATGEHITTVVN
CCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
IGIGGSDLGPAMAYQALRDYSDRSIAVRFVSNVDPTDIWEATHDLDPARTLFIVASKTFT
ECCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEEEECCHHH
TLETLANARAARAWLTAALGQDAVAHHFVAVSTNAEKVAEFGIDTANMFEFWDWVGGRYS
HHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEECCHHHHHHHCCCHHHHHHHHHHCCCCCC
MDSAIGLALMVAIGPHHFREMLAGFHAMDVHFRNTPFERNLPVLLGVLGLWYRDFFGAQS
CHHHHHHHHHHHHCHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC
HAVLPYSQYLDRFPAYLQQLDMESNGKSVDLAGRPVPVPTGPVVWGTPGTNGQHAYFQLL
CEECCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCHHHHHHH
HQGTTVVPADFIGFLAPNHPGVGDVDQHVLLMANFFAQTEALAFGRTAEEVAAEGVDAAL
HCCCEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEE
VPHRTFAGNRPTNTLLAPKLTPFALGQLVALYEHKVFTQGVVWGVNSYDQWGVELGKVLA
CCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHH
GRIIPELADPSAPPRHDSSTNALINLFRSV
HHHHHHHCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA