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The map label for this gene is pdhB [H]

Identifier: 158318985

GI number: 158318985

Start: 8872097

End: 8873263

Strand: Direct

Name: pdhB [H]

Synonym: Franean1_7268

Alternate gene names: 158318985

Gene position: 8872097-8873263 (Clockwise)

Preceding gene: 158318984

Following gene: 158318986

Centisome position: 98.78

GC content: 70.87

Gene sequence:

>1167_bases
TTGACGACCAGCGATACGGCCACGGGGGCGGCAACCGGCCCGATCGGCTCTATCGACGCCATCGACCCGGGTCCGGTCGA
TCCGGTCTCCATCGGTCCGGACTCGATCGCTCCGGACTCTGTCGGTTCCGTGGGCCCGGCGACGGACGGGGAGCCGCCGG
CGAGCCCCCGCCAGACCCTGACCCTGGCGAAGGCGCTGAACACGGGCCTGCTCTCGGCCATGGCCGCCGACCCGAAGGTC
GTGATCATGGGCGAAGACGTCGGCAAGCTCGGCGGCGTCTTCCGTATCACCGACGGCCTGCAGGCCCGGTTCGGCGAGGA
CCGCGTCATCGACACCCCGCTCGCCGAGTCGGCCATCGTCGGCACCGCCATCGGCCTGGCCATGCGCGGGTTCCGCCCGG
TCTGCGAGATCCAGTTCGACGGCTTCGTCTACCCGGCGTTCGACCAGATCGTCAGCCAGCTCGCCAAGCTGCACTACCGC
TCGGCCGGACGGATCCGGCTGCCGGTCACGATCCGCATCCCCTACGGCGGCGGGATCGGAGCGGTCGAGCACCACAGCGA
GTCACCCGAGGCGTACTTCTGCCACACCGCCGGGCTGCGGGTCGTCACCTGCTCCAACCCTGCCGACGCGCACCTCATGA
TCCAGCAGGCGGTGGCCTCGGACGATCCAGTGATCTTCCTGGAGCCCAAGCGCCGTTACTGGGAGAAGGGCGAGGTCGAC
ACCACCCCACTCGCCAGCATGCCGGTGCAGGAGCAGCTCGCGCTGCACACCGCGCGGGTGGTGCGGCCCGGGGCCGACGC
CACCCTGGTCGCCTACGGCCCGATGGTCCGCACCTGCCTGGACGCCGCCCAGGTGGCCGCCGAGGACGACGGCAGCTCGC
TCGAGGTGATCGACCTGCGCTCGCTCTCGCCGCTCGACCTCGACCCGGTCGTCGAGTCGGTGCGCCGCACGGGACGTCTC
GTGGTGGTGCACGAGGCTCCGTCGAACGTCTCGCTGTCCTCGGAGATCGCGGCCCGGGTCACCGAGCAGGCGTTCTACCA
CCTGGAGTCGCCGGTGCTGCGGGTCACCGGGTTCGACACCCCGTACCCCCCGGCCCGGCTGGAAGACCACTACCTCCCCG
ACGTCGACCGGATCCTCGACGCCGTCGACCGATCGTTCGGCTACTGA

Upstream 100 bases:

>100_bases
ACCCGCCCGAGGCCGCACTGTTCGACCACGTCCAGGTGACGGAGAACAATCTGGTTGCCGCCGAGCGCGCCGCGTTCACG
GAACTACGGGGAGCATTGCT

Downstream 100 bases:

>100_bases
GGAGATCTCCGGTGACCCATCGACAGTTCCGCCTCCCCGATCTCGGCGAGGGGCTGACCGAGGCGGAGATCGTCCGGTGG
CTGGTGGAGGTCGGCGAGAC

Product: transketolase central region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTTSDTATGAATGPIGSIDAIDPGPVDPVSIGPDSIAPDSVGSVGPATDGEPPASPRQTLTLAKALNTGLLSAMAADPKV
VIMGEDVGKLGGVFRITDGLQARFGEDRVIDTPLAESAIVGTAIGLAMRGFRPVCEIQFDGFVYPAFDQIVSQLAKLHYR
SAGRIRLPVTIRIPYGGGIGAVEHHSESPEAYFCHTAGLRVVTCSNPADAHLMIQQAVASDDPVIFLEPKRRYWEKGEVD
TTPLASMPVQEQLALHTARVVRPGADATLVAYGPMVRTCLDAAQVAAEDDGSSLEVIDLRSLSPLDLDPVVESVRRTGRL
VVVHEAPSNVSLSSEIAARVTEQAFYHLESPVLRVTGFDTPYPPARLEDHYLPDVDRILDAVDRSFGY

Sequences:

>Translated_388_residues
MTTSDTATGAATGPIGSIDAIDPGPVDPVSIGPDSIAPDSVGSVGPATDGEPPASPRQTLTLAKALNTGLLSAMAADPKV
VIMGEDVGKLGGVFRITDGLQARFGEDRVIDTPLAESAIVGTAIGLAMRGFRPVCEIQFDGFVYPAFDQIVSQLAKLHYR
SAGRIRLPVTIRIPYGGGIGAVEHHSESPEAYFCHTAGLRVVTCSNPADAHLMIQQAVASDDPVIFLEPKRRYWEKGEVD
TTPLASMPVQEQLALHTARVVRPGADATLVAYGPMVRTCLDAAQVAAEDDGSSLEVIDLRSLSPLDLDPVVESVRRTGRL
VVVHEAPSNVSLSSEIAARVTEQAFYHLESPVLRVTGFDTPYPPARLEDHYLPDVDRILDAVDRSFGY
>Mature_387_residues
TTSDTATGAATGPIGSIDAIDPGPVDPVSIGPDSIAPDSVGSVGPATDGEPPASPRQTLTLAKALNTGLLSAMAADPKVV
IMGEDVGKLGGVFRITDGLQARFGEDRVIDTPLAESAIVGTAIGLAMRGFRPVCEIQFDGFVYPAFDQIVSQLAKLHYRS
AGRIRLPVTIRIPYGGGIGAVEHHSESPEAYFCHTAGLRVVTCSNPADAHLMIQQAVASDDPVIFLEPKRRYWEKGEVDT
TPLASMPVQEQLALHTARVVRPGADATLVAYGPMVRTCLDAAQVAAEDDGSSLEVIDLRSLSPLDLDPVVESVRRTGRLV
VVHEAPSNVSLSSEIAARVTEQAFYHLESPVLRVTGFDTPYPPARLEDHYLPDVDRILDAVDRSFGY

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557353, Length=346, Percent_Identity=41.0404624277457, Blast_Score=255, Evalue=4e-68,
Organism=Homo sapiens, GI34101272, Length=346, Percent_Identity=41.0404624277457, Blast_Score=255, Evalue=4e-68,
Organism=Homo sapiens, GI156564403, Length=330, Percent_Identity=33.9393939393939, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI291084858, Length=330, Percent_Identity=32.4242424242424, Blast_Score=185, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17506935, Length=334, Percent_Identity=42.814371257485, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17538422, Length=331, Percent_Identity=36.8580060422961, Blast_Score=207, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6319698, Length=333, Percent_Identity=33.9339339339339, Blast_Score=207, Evalue=3e-54,
Organism=Drosophila melanogaster, GI160714832, Length=328, Percent_Identity=39.6341463414634, Blast_Score=234, Evalue=6e-62,
Organism=Drosophila melanogaster, GI160714828, Length=328, Percent_Identity=39.6341463414634, Blast_Score=234, Evalue=9e-62,
Organism=Drosophila melanogaster, GI21358145, Length=339, Percent_Identity=37.1681415929204, Blast_Score=217, Evalue=9e-57,
Organism=Drosophila melanogaster, GI24650940, Length=339, Percent_Identity=37.1681415929204, Blast_Score=217, Evalue=9e-57,
Organism=Drosophila melanogaster, GI24650943, Length=91, Percent_Identity=40.6593406593407, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24650945, Length=91, Percent_Identity=40.6593406593407, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 41227; Mature: 41096

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSDTATGAATGPIGSIDAIDPGPVDPVSIGPDSIAPDSVGSVGPATDGEPPASPRQTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
TLAKALNTGLLSAMAADPKVVIMGEDVGKLGGVFRITDGLQARFGEDRVIDTPLAESAIV
HHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCEEEECCCHHHHCCCCCEECCCCHHHHHH
GTAIGLAMRGFRPVCEIQFDGFVYPAFDQIVSQLAKLHYRSAGRIRLPVTIRIPYGGGIG
HHHHHHHHHCCCCEEEEEECCEEEHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCC
AVEHHSESPEAYFCHTAGLRVVTCSNPADAHLMIQQAVASDDPVIFLEPKRRYWEKGEVD
CCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCHHCCCCCCCC
TTPLASMPVQEQLALHTARVVRPGADATLVAYGPMVRTCLDAAQVAAEDDGSSLEVIDLR
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCEEEEEEEC
SLSPLDLDPVVESVRRTGRLVVVHEAPSNVSLSSEIAARVTEQAFYHLESPVLRVTGFDT
CCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCC
PYPPARLEDHYLPDVDRILDAVDRSFGY
CCCCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTSDTATGAATGPIGSIDAIDPGPVDPVSIGPDSIAPDSVGSVGPATDGEPPASPRQTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
TLAKALNTGLLSAMAADPKVVIMGEDVGKLGGVFRITDGLQARFGEDRVIDTPLAESAIV
HHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCEEEECCCHHHHCCCCCEECCCCHHHHHH
GTAIGLAMRGFRPVCEIQFDGFVYPAFDQIVSQLAKLHYRSAGRIRLPVTIRIPYGGGIG
HHHHHHHHHCCCCEEEEEECCEEEHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCC
AVEHHSESPEAYFCHTAGLRVVTCSNPADAHLMIQQAVASDDPVIFLEPKRRYWEKGEVD
CCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCHHCCCCCCCC
TTPLASMPVQEQLALHTARVVRPGADATLVAYGPMVRTCLDAAQVAAEDDGSSLEVIDLR
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCEEEEEEEC
SLSPLDLDPVVESVRRTGRLVVVHEAPSNVSLSSEIAARVTEQAFYHLESPVLRVTGFDT
CCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCC
PYPPARLEDHYLPDVDRILDAVDRSFGY
CCCCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA