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The map label for this gene is fur [H]

Identifier: 158318980

GI number: 158318980

Start: 8866064

End: 8866591

Strand: Direct

Name: fur [H]

Synonym: Franean1_7263

Alternate gene names: 158318980

Gene position: 8866064-8866591 (Clockwise)

Preceding gene: 158318977

Following gene: 158318984

Centisome position: 98.71

GC content: 74.24

Gene sequence:

>528_bases
ATGTCAGCGGCCTCCGACCGGGCGGCAGGCGGCGCCGGCGCTGGCTCTGGTGACCGCCCGAACGGGGCGGTGTCCCGCCC
GGGTCGCGGCCGCGGCACCTCCGTCCGGGCCACCCGGCAGGGCGACGCGGTCTCCTCCGCGCTCGCGGCGACGAACGCCT
TCACCAGCGCGCAGGACCTGCACGCCCGCCTACGCCAGGAGGGCCAGTCCGTCGGCCTGACAACCGTCTACCGTCACCTG
CAGGTGCTGGCCGACCGCGGCGAGGTGGACGTCCTGCGCCGGGATGACGGCGAGACCGTGTACCGGCGGTGCACCACGGA
CGGTCACCACCACCATCTCGTGTGCCGCCACTGCGGCCACACGGTGGAGATCGCCGGCCCCGAGATCGAGGCCTGGACGT
CCTCCGTGGCCAGCGCGGAGGGCTTCACCGACGTCGTACACACCGTCGAGATCTACGGAACGTGCGCACGGTGCGCCGCC
TCACGCAACAGCGACAACAGCCCCGGCCGCCCTCGCGGCGGCGGCTGA

Upstream 100 bases:

>100_bases
AGAACTGAGGAGATCGCGCGCCCTCCAGACGGGCCGGGTAGATGAGAGAGTGGATGTCGTGGCGAGTGTGGAAGGCGAGC
GGGTGAGCTCCCCGCGCGGC

Downstream 100 bases:

>100_bases
GCGAAACACGCGGAGACGAACGAGCGAACGCGCGAACGCGCGAAAACGGCTGAACGAACGCCCGCGAAAGCGGTTGGAGA
AATGTAAAACGGCCGGGACA

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSAASDRAAGGAGAGSGDRPNGAVSRPGRGRGTSVRATRQGDAVSSALAATNAFTSAQDLHARLRQEGQSVGLTTVYRHL
QVLADRGEVDVLRRDDGETVYRRCTTDGHHHHLVCRHCGHTVEIAGPEIEAWTSSVASAEGFTDVVHTVEIYGTCARCAA
SRNSDNSPGRPRGGG

Sequences:

>Translated_175_residues
MSAASDRAAGGAGAGSGDRPNGAVSRPGRGRGTSVRATRQGDAVSSALAATNAFTSAQDLHARLRQEGQSVGLTTVYRHL
QVLADRGEVDVLRRDDGETVYRRCTTDGHHHHLVCRHCGHTVEIAGPEIEAWTSSVASAEGFTDVVHTVEIYGTCARCAA
SRNSDNSPGRPRGGG
>Mature_174_residues
SAASDRAAGGAGAGSGDRPNGAVSRPGRGRGTSVRATRQGDAVSSALAATNAFTSAQDLHARLRQEGQSVGLTTVYRHLQ
VLADRGEVDVLRRDDGETVYRRCTTDGHHHHLVCRHCGHTVEIAGPEIEAWTSSVASAEGFTDVVHTVEIYGTCARCAAS
RNSDNSPGRPRGGG

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of the fbp protein [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=106, Percent_Identity=36.7924528301887, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18275; Mature: 18144

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAASDRAAGGAGAGSGDRPNGAVSRPGRGRGTSVRATRQGDAVSSALAATNAFTSAQDL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCHHHH
HARLRQEGQSVGLTTVYRHLQVLADRGEVDVLRRDDGETVYRRCTTDGHHHHLVCRHCGH
HHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCHHHHHCCC
TVEIAGPEIEAWTSSVASAEGFTDVVHTVEIYGTCARCAASRNSDNSPGRPRGGG
EEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAASDRAAGGAGAGSGDRPNGAVSRPGRGRGTSVRATRQGDAVSSALAATNAFTSAQDL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCHHHH
HARLRQEGQSVGLTTVYRHLQVLADRGEVDVLRRDDGETVYRRCTTDGHHHHLVCRHCGH
HHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCHHHHHCCC
TVEIAGPEIEAWTSSVASAEGFTDVVHTVEIYGTCARCAASRNSDNSPGRPRGGG
EEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8406856 [H]