Click here to switch to the map view.

The map label for this gene is yfbQ [H]

Identifier: 158318976

GI number: 158318976

Start: 8860895

End: 8862109

Strand: Direct

Name: yfbQ [H]

Synonym: Franean1_7259

Alternate gene names: 158318976

Gene position: 8860895-8862109 (Clockwise)

Preceding gene: 158318973

Following gene: 158318977

Centisome position: 98.65

GC content: 69.14

Gene sequence:

>1215_bases
ATGGAGTTCGCCCAGTCCGACAAGCTCGCCGACGTCTGCTACGACGTCCGAGGTCCCATCCTCGACGAGGCGACCCGGCT
GGAGGCCGCAGGCCAGCGCATCCTGAAGCTGAACATCGGCAACCCCGCCCCGTTCGGCTTCTCCGCGCCGCCTTCGGTGC
TCGCCGCCGTGGTCGAGAACCTCGCGGCAGCACAGGGCTACAGCGACTCCAAGGGCCTGCTCCCCGCCCGTGAGGCCGTC
GTGCGCTACGCGGCCGGCAAGGGAATGACCAGCGTCACGCCCGACGACGTCTACCTCGGCAACGGCGTCTCCGAGCTGAT
CATGATGTCGCTGCAGGCGCTGCTGAACAACGGCGACGAGGTACTCCTCCCCGCTCCCGACTACCCGCTGTGGACGGCGG
TGGTCAGCCTCACCGGCGGGCGGCCCGTGCACTACCTGTGCGACGAGTCCGCGGGCTGGAATCCCGACCTCGACGACATC
ATCCGCAAGATCACCCCACGTACCCGCGCCATCGTGATCATCAACCCGAACAACCCGACCGGGGCCGTCTACGACCGGCC
GGTGCTCGAGGAGCTCATCGAGGTCGCCCGCCGGCACCACCTGATGCTGTTCTCCGACGAGATCTACGACCGCATCCTCT
ACGACGGCGCGGAGCACCACTCGCCCGCGGCGCTCGCCCCCGACCTGTTCTGCGTGACGTTCAACGGGCTGTCGAAGGCC
TACCGGTTGGCGGGCTTCCGCTCCGGGTGGATGACCCTCTCCGGGCCCCGCCAGCACGCGTCGAGCTACATCGAGGGCCT
GAACATCCTGGCGAACATGCGCCTGTGCGCGAACGTGCCCGGCCAGTTCGCGCTCCAGGCCGCGCTCGCCGAGGGCAGCG
GTGCCGGCGATCTCGTCCTGCCCGGCGGCCGGCTGCTCGAGCAGCGCGACACGGTGGTGAAGCTGCTCAACGACATCCCC
GGGGTGTCGTGTGTGCCCCCGCGCGGCGCGCTGTACGCGTTCCCCCGCATCGATCCCGAGGTCTACCCGATCGACGACGA
CGAGAGCTTCGTGCTCGACCTGCTGCAGGCCGAGCGGATCCTGCTGGTGCAGGGCACCGGGTTCAACTGGCCGCGGCCCG
ACCATGTCCGGCTTGTGACCTTGCCGTGCGTCGACGACCTGACCGACGCAGTCGGTCGGATCGACCGGTTCCTGACCACC
TACGCTCGGACCTGA

Upstream 100 bases:

>100_bases
ACCATGATCCAAGTATGCCAGCGCCGCACACCTACCAGGGCTACGGTCCATACCCGATTCCCCTGACGGCTGAAGGCGCC
AATCCCCTCGGGAGCGCCTG

Downstream 100 bases:

>100_bases
GCGCCTCGTCCGGATTTGCCGGGCGGCGCCGCACAGGCGATGTCCACAAGGGACGGGTGCTCTGTGGACAGAACCTGTGG
ACAACCGGGTGGAGGACACG

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MEFAQSDKLADVCYDVRGPILDEATRLEAAGQRILKLNIGNPAPFGFSAPPSVLAAVVENLAAAQGYSDSKGLLPAREAV
VRYAAGKGMTSVTPDDVYLGNGVSELIMMSLQALLNNGDEVLLPAPDYPLWTAVVSLTGGRPVHYLCDESAGWNPDLDDI
IRKITPRTRAIVIINPNNPTGAVYDRPVLEELIEVARRHHLMLFSDEIYDRILYDGAEHHSPAALAPDLFCVTFNGLSKA
YRLAGFRSGWMTLSGPRQHASSYIEGLNILANMRLCANVPGQFALQAALAEGSGAGDLVLPGGRLLEQRDTVVKLLNDIP
GVSCVPPRGALYAFPRIDPEVYPIDDDESFVLDLLQAERILLVQGTGFNWPRPDHVRLVTLPCVDDLTDAVGRIDRFLTT
YART

Sequences:

>Translated_404_residues
MEFAQSDKLADVCYDVRGPILDEATRLEAAGQRILKLNIGNPAPFGFSAPPSVLAAVVENLAAAQGYSDSKGLLPAREAV
VRYAAGKGMTSVTPDDVYLGNGVSELIMMSLQALLNNGDEVLLPAPDYPLWTAVVSLTGGRPVHYLCDESAGWNPDLDDI
IRKITPRTRAIVIINPNNPTGAVYDRPVLEELIEVARRHHLMLFSDEIYDRILYDGAEHHSPAALAPDLFCVTFNGLSKA
YRLAGFRSGWMTLSGPRQHASSYIEGLNILANMRLCANVPGQFALQAALAEGSGAGDLVLPGGRLLEQRDTVVKLLNDIP
GVSCVPPRGALYAFPRIDPEVYPIDDDESFVLDLLQAERILLVQGTGFNWPRPDHVRLVTLPCVDDLTDAVGRIDRFLTT
YART
>Mature_404_residues
MEFAQSDKLADVCYDVRGPILDEATRLEAAGQRILKLNIGNPAPFGFSAPPSVLAAVVENLAAAQGYSDSKGLLPAREAV
VRYAAGKGMTSVTPDDVYLGNGVSELIMMSLQALLNNGDEVLLPAPDYPLWTAVVSLTGGRPVHYLCDESAGWNPDLDDI
IRKITPRTRAIVIINPNNPTGAVYDRPVLEELIEVARRHHLMLFSDEIYDRILYDGAEHHSPAALAPDLFCVTFNGLSKA
YRLAGFRSGWMTLSGPRQHASSYIEGLNILANMRLCANVPGQFALQAALAEGSGAGDLVLPGGRLLEQRDTVVKLLNDIP
GVSCVPPRGALYAFPRIDPEVYPIDDDESFVLDLLQAERILLVQGTGFNWPRPDHVRLVTLPCVDDLTDAVGRIDRFLTT
YART

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=481, Percent_Identity=28.2744282744283, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI215599424, Length=386, Percent_Identity=29.7927461139896, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI4885351, Length=436, Percent_Identity=28.4403669724771, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI4507369, Length=391, Percent_Identity=27.3657289002558, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI95147551, Length=247, Percent_Identity=26.7206477732794, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI169881279, Length=247, Percent_Identity=26.7206477732794, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI56713254, Length=261, Percent_Identity=25.6704980842912, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI56713256, Length=261, Percent_Identity=25.6704980842912, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI169881281, Length=233, Percent_Identity=25.7510729613734, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1788627, Length=399, Percent_Identity=62.9072681704261, Blast_Score=548, Evalue=1e-157,
Organism=Escherichia coli, GI1788722, Length=395, Percent_Identity=25.3164556962025, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786816, Length=338, Percent_Identity=24.2603550295858, Blast_Score=85, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17567663, Length=381, Percent_Identity=30.1837270341207, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI71981209, Length=472, Percent_Identity=28.1779661016949, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71981215, Length=295, Percent_Identity=27.7966101694915, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=314, Percent_Identity=26.4331210191083, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=314, Percent_Identity=26.4331210191083, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=217, Percent_Identity=27.1889400921659, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323118, Length=365, Percent_Identity=27.1232876712329, Blast_Score=122, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6320317, Length=354, Percent_Identity=27.683615819209, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322401, Length=221, Percent_Identity=25.3393665158371, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI18859735, Length=380, Percent_Identity=27.1052631578947, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI45551451, Length=464, Percent_Identity=27.3706896551724, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24641770, Length=464, Percent_Identity=27.3706896551724, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24641760, Length=464, Percent_Identity=27.3706896551724, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24641768, Length=464, Percent_Identity=27.3706896551724, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24641766, Length=464, Percent_Identity=27.3706896551724, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24641764, Length=464, Percent_Identity=27.3706896551724, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573069, Length=332, Percent_Identity=23.7951807228916, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24646114, Length=332, Percent_Identity=23.7951807228916, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28573067, Length=332, Percent_Identity=23.7951807228916, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28573065, Length=332, Percent_Identity=23.7951807228916, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 43945; Mature: 43945

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFAQSDKLADVCYDVRGPILDEATRLEAAGQRILKLNIGNPAPFGFSAPPSVLAAVVEN
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
LAAAQGYSDSKGLLPAREAVVRYAAGKGMTSVTPDDVYLGNGVSELIMMSLQALLNNGDE
HHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCE
VLLPAPDYPLWTAVVSLTGGRPVHYLCDESAGWNPDLDDIIRKITPRTRAIVIINPNNPT
EEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCC
GAVYDRPVLEELIEVARRHHLMLFSDEIYDRILYDGAEHHSPAALAPDLFCVTFNGLSKA
CCCCCCHHHHHHHHHHHHHEEEEECHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHH
YRLAGFRSGWMTLSGPRQHASSYIEGLNILANMRLCANVPGQFALQAALAEGSGAGDLVL
HHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEE
PGGRLLEQRDTVVKLLNDIPGVSCVPPRGALYAFPRIDPEVYPIDDDESFVLDLLQAERI
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCEEEECCCCHHHHHHHHHCCEE
LLVQGTGFNWPRPDHVRLVTLPCVDDLTDAVGRIDRFLTTYART
EEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFAQSDKLADVCYDVRGPILDEATRLEAAGQRILKLNIGNPAPFGFSAPPSVLAAVVEN
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
LAAAQGYSDSKGLLPAREAVVRYAAGKGMTSVTPDDVYLGNGVSELIMMSLQALLNNGDE
HHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCE
VLLPAPDYPLWTAVVSLTGGRPVHYLCDESAGWNPDLDDIIRKITPRTRAIVIINPNNPT
EEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCC
GAVYDRPVLEELIEVARRHHLMLFSDEIYDRILYDGAEHHSPAALAPDLFCVTFNGLSKA
CCCCCCHHHHHHHHHHHHHEEEEECHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHH
YRLAGFRSGWMTLSGPRQHASSYIEGLNILANMRLCANVPGQFALQAALAEGSGAGDLVL
HHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEE
PGGRLLEQRDTVVKLLNDIPGVSCVPPRGALYAFPRIDPEVYPIDDDESFVLDLLQAERI
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCEEEECCCCHHHHHHHHHCCEE
LLVQGTGFNWPRPDHVRLVTLPCVDDLTDAVGRIDRFLTTYART
EEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]