| Definition | Frankia sp. EAN1pec chromosome, complete genome. |
|---|---|
| Accession | NC_009921 |
| Length | 8,982,042 |
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The map label for this gene is lvr [H]
Identifier: 158318901
GI number: 158318901
Start: 8770942
End: 8771691
Strand: Direct
Name: lvr [H]
Synonym: Franean1_7184
Alternate gene names: 158318901
Gene position: 8770942-8771691 (Clockwise)
Preceding gene: 158318898
Following gene: 158318903
Centisome position: 97.65
GC content: 70.0
Gene sequence:
>750_bases ATGCCGCGTTTGGACGGGAAGGTCGCGATCGTCACCGGCGCCGGGATCGGCCAGGGACGGTCCACGGCGCTTCGGCTCGC CCGCGAGGGAGCCAGCGTTGTCGCCGCGGACGTCAGCGGCGCGGAGAAGGAGACCGCCGAGGGCAACGAGGCCATTGTTC CGTTACACACGGACGTCACCCGGGCGGCCGAGGTGGAGGCCCTCGTCCGGGAGACGACCGAGCGGTTCGGGCGGCTCGAC ATCCTCTGCAACGTGGTGGGTGTCGCCGGGATCGCGCAGGCCCCGGTGCCCGACATCGAGGAGTCCGAGTTCGATCTCCT CGTCAACATCAATCTCAAGAGCGTTCTGCTCGGCATGAAGTACGCGATTCCGGCGATGGTGGCCGGCGGCGGTGGCTCGA TCGTCAACTGGTCCTCGGTGGGCGCGCTCGTCTCCTCGCCCAACACGGCCGTGTACGGCGCGACGAAGGCCGGCATTCTC TCGATGACCAGGGCGGCGGCCCGGGAGTGGGGCAGGTCCGGCGTGCGGGTGAACGCCATCTGCCCCGGATTCGTCTACCC GACCGGGATGACCTTGATGGGCGAGAAGGAGTACCCGCAGGCCTTCCGGAACGCCTCCGCGAAGGCTGCGCTCGACCGGC CCGGCCATCCGGACGAGATCGCCGCCGTCGCCGCGTTCCTGGCCTCGGACGACGCCTCGTTCATGACCGGCTCCCACGTC GTCGTGGACGGCGGCTGGACGGCCGGCTGA
Upstream 100 bases:
>100_bases CGGCCTGATCGGCGGAGGCGTCGAACCGATCCCCTTATTCGAGCGAGCGCTCACTTGCATAATGGCGGGAACTCACGAAC TCCGACGAAGGGCGAGGAAC
Downstream 100 bases:
>100_bases CGCGGTCCCTCGACCAGACCGGCCGGATGGCGAGGGTGATTCCTACGCCACCCGGCCGAGTTAGCCGAGTTAGCCGAGCC GGCCTGACCGCCCGTCGACG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: (6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase [H]
Number of amino acids: Translated: 249; Mature: 248
Protein sequence:
>249_residues MPRLDGKVAIVTGAGIGQGRSTALRLAREGASVVAADVSGAEKETAEGNEAIVPLHTDVTRAAEVEALVRETTERFGRLD ILCNVVGVAGIAQAPVPDIEESEFDLLVNINLKSVLLGMKYAIPAMVAGGGGSIVNWSSVGALVSSPNTAVYGATKAGIL SMTRAAAREWGRSGVRVNAICPGFVYPTGMTLMGEKEYPQAFRNASAKAALDRPGHPDEIAAVAAFLASDDASFMTGSHV VVDGGWTAG
Sequences:
>Translated_249_residues MPRLDGKVAIVTGAGIGQGRSTALRLAREGASVVAADVSGAEKETAEGNEAIVPLHTDVTRAAEVEALVRETTERFGRLD ILCNVVGVAGIAQAPVPDIEESEFDLLVNINLKSVLLGMKYAIPAMVAGGGGSIVNWSSVGALVSSPNTAVYGATKAGIL SMTRAAAREWGRSGVRVNAICPGFVYPTGMTLMGEKEYPQAFRNASAKAALDRPGHPDEIAAVAAFLASDDASFMTGSHV VVDGGWTAG >Mature_248_residues PRLDGKVAIVTGAGIGQGRSTALRLAREGASVVAADVSGAEKETAEGNEAIVPLHTDVTRAAEVEALVRETTERFGRLDI LCNVVGVAGIAQAPVPDIEESEFDLLVNINLKSVLLGMKYAIPAMVAGGGGSIVNWSSVGALVSSPNTAVYGATKAGILS MTRAAAREWGRSGVRVNAICPGFVYPTGMTLMGEKEYPQAFRNASAKAALDRPGHPDEIAAVAAFLASDDASFMTGSHVV VDGGWTAG
Specific function: Catalyzes the regio- and stereoselective reversible NAD- dependent reduction of (6R)-2,2,6-trimethyl-1,4-cyclohexanedione (levodione) to (4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexanone (actinol) [H]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=36, Blast_Score=147, Evalue=1e-35, Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=34.6153846153846, Blast_Score=127, Evalue=1e-29, Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=31.6205533596838, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=32.0158102766798, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=30.2040816326531, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI31542939, Length=197, Percent_Identity=36.5482233502538, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI59889578, Length=197, Percent_Identity=36.0406091370558, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=31.7460317460317, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=27.843137254902, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=28.4552845528455, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=30.4347826086957, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4504505, Length=191, Percent_Identity=28.7958115183246, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=33.8983050847458, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=29.3893129770992, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI209862901, Length=196, Percent_Identity=32.6530612244898, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI19923983, Length=196, Percent_Identity=32.6530612244898, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI126723191, Length=187, Percent_Identity=30.4812834224599, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=36.71875, Blast_Score=141, Evalue=4e-35, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=31.2, Blast_Score=115, Evalue=4e-27, Organism=Escherichia coli, GI1789378, Length=260, Percent_Identity=32.3076923076923, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=28.7449392712551, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=30.6772908366534, Blast_Score=100, Evalue=7e-23, Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=31.6, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=29.2, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=30.9236947791165, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=30.5220883534137, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=30.0395256916996, Blast_Score=77, Evalue=8e-16, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=29.1828793774319, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=27.2, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=35.0806451612903, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=33.2046332046332, Blast_Score=114, Evalue=4e-26, Organism=Caenorhabditis elegans, GI17559104, Length=271, Percent_Identity=33.9483394833948, Blast_Score=113, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17562910, Length=277, Percent_Identity=33.9350180505415, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=33.7121212121212, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=35.1648351648352, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=31.3253012048193, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=31.2, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=30.4, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17562904, Length=274, Percent_Identity=31.7518248175182, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=31.9702602230483, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=32.4817518248175, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17560332, Length=277, Percent_Identity=34.6570397111913, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=29.6875, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=31.8352059925094, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=31.0861423220974, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=32.4, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17538486, Length=282, Percent_Identity=30.1418439716312, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17563726, Length=268, Percent_Identity=29.4776119402985, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=29.4339622641509, Blast_Score=89, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=30.5343511450382, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17560150, Length=272, Percent_Identity=30.5147058823529, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=32.5842696629214, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=28.7313432835821, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=29.4117647058824, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17561272, Length=255, Percent_Identity=32.156862745098, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17568967, Length=256, Percent_Identity=27.34375, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=27.34375, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=27.1653543307087, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71982365, Length=209, Percent_Identity=25.8373205741627, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17508651, Length=246, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17564282, Length=202, Percent_Identity=31.1881188118812, Blast_Score=69, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=30.7392996108949, Blast_Score=87, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6322861, Length=188, Percent_Identity=26.5957446808511, Blast_Score=72, Evalue=6e-14, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=38.1526104417671, Blast_Score=132, Evalue=3e-31, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=37.109375, Blast_Score=128, Evalue=3e-30, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=36.6935483870968, Blast_Score=127, Evalue=1e-29, Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=34.2412451361868, Blast_Score=124, Evalue=5e-29, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=34.6456692913386, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=33.0739299610895, Blast_Score=116, Evalue=2e-26, Organism=Drosophila melanogaster, GI24644337, Length=193, Percent_Identity=35.2331606217617, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=31.8548387096774, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=30.0395256916996, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI18859837, Length=259, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI24665243, Length=201, Percent_Identity=31.8407960199005, Blast_Score=80, Evalue=9e-16, Organism=Drosophila melanogaster, GI221331218, Length=201, Percent_Identity=31.8407960199005, Blast_Score=80, Evalue=9e-16, Organism=Drosophila melanogaster, GI24665247, Length=202, Percent_Identity=32.1782178217822, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI221331216, Length=202, Percent_Identity=32.1782178217822, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI21355631, Length=160, Percent_Identity=31.875, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24649181, Length=190, Percent_Identity=30.5263157894737, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24665264, Length=194, Percent_Identity=31.9587628865979, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI21357673, Length=195, Percent_Identity=27.6923076923077, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24640492, Length=216, Percent_Identity=25.462962962963, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI281364892, Length=204, Percent_Identity=26.4705882352941, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 25623; Mature: 25492
Theoretical pI: Translated: 4.92; Mature: 4.92
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPRLDGKVAIVTGAGIGQGRSTALRLAREGASVVAADVSGAEKETAEGNEAIVPLHTDVT CCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEEECCHH RAAEVEALVRETTERFGRLDILCNVVGVAGIAQAPVPDIEESEFDLLVNINLKSVLLGMK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHH YAIPAMVAGGGGSIVNWSSVGALVSSPNTAVYGATKAGILSMTRAAAREWGRSGVRVNAI HHCCEEEECCCCCEEEHHHCCHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCEEEEE CPGFVYPTGMTLMGEKEYPQAFRNASAKAALDRPGHPDEIAAVAAFLASDDASFMTGSHV CCCCCCCCCEEEECCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCEE VVDGGWTAG EEECCCCCC >Mature Secondary Structure PRLDGKVAIVTGAGIGQGRSTALRLAREGASVVAADVSGAEKETAEGNEAIVPLHTDVT CCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEEECCHH RAAEVEALVRETTERFGRLDILCNVVGVAGIAQAPVPDIEESEFDLLVNINLKSVLLGMK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHH YAIPAMVAGGGGSIVNWSSVGALVSSPNTAVYGATKAGILSMTRAAAREWGRSGVRVNAI HHCCEEEECCCCCEEEHHHCCHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCEEEEE CPGFVYPTGMTLMGEKEYPQAFRNASAKAALDRPGHPDEIAAVAAFLASDDASFMTGSHV CCCCCCCCCEEEECCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCEE VVDGGWTAG EEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11388460; 10508066 [H]