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The map label for this gene is cmtA [H]

Identifier: 158318800

GI number: 158318800

Start: 8631576

End: 8631884

Strand: Reverse

Name: cmtA [H]

Synonym: Franean1_7072

Alternate gene names: 158318800

Gene position: 8631884-8631576 (Counterclockwise)

Preceding gene: 158318801

Following gene: 158318799

Centisome position: 96.1

GC content: 65.37

Gene sequence:

>309_bases
ATGGCAACCATCAAGGGTGAGGACATCCACAAGCTCGTTGTCGCCTGCGACGCGGGAATGGGAAGCAGCGTGATGCTGGC
CAGCCAGCTCCGCAAGCAGCTCAAGGCGTACGCGGTCACCGTCGAGCACACCCCGGTGAACTCCATTCCGGCGGACGCCG
ATCTGGTCGTCTGCCACGTCGGCCTGGCTGACCGGGCCCGCCGGGGGGTGCCGGACAAGCCGATCGTGACATTCCAGGTG
TTCATAGGTGATCCGGCCGTGGCCAACGTGCTGGCCGCCATCCGCGAGGGGAAAGTGCTCGATGTCTGA

Upstream 100 bases:

>100_bases
TCCGGGCAGTACGAGCGAGGGGAAGGTTTCCAGCGGCGCGGCTAGCCCGGTGACAGCAGCCTCGCAGCGGCTTTCCGCAG
CATCGGAAGGGTGATGGCAT

Downstream 100 bases:

>100_bases
GGGACACGGTGCGGCGCGGCAGGACAGCCCCGGCGGCACCATGAGCCGGCTGCTCGACCCGAGCGCGGTGCGCCTCGCCG
AGGTGGCAGCGAGCCGGGAG

Product: phosphotransferase system lactose/cellobiose-specific IIB subunit

Products: NA

Alternate protein names: EIICB-Mtl; EII-Mtl; Mannitol permease IIC component; PTS system mannitol-specific EIIC component; Mannitol-specific phosphotransferase enzyme IIB component; PTS system mannitol-specific EIIB component [H]

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MATIKGEDIHKLVVACDAGMGSSVMLASQLRKQLKAYAVTVEHTPVNSIPADADLVVCHVGLADRARRGVPDKPIVTFQV
FIGDPAVANVLAAIREGKVLDV

Sequences:

>Translated_102_residues
MATIKGEDIHKLVVACDAGMGSSVMLASQLRKQLKAYAVTVEHTPVNSIPADADLVVCHVGLADRARRGVPDKPIVTFQV
FIGDPAVANVLAAIREGKVLDV
>Mature_101_residues
ATIKGEDIHKLVVACDAGMGSSVMLASQLRKQLKAYAVTVEHTPVNSIPADADLVVCHVGLADRARRGVPDKPIVTFQVF
IGDPAVANVLAAIREGKVLDV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2213

COG function: function code G; Phosphotransferase system, mannitol-specific IIBC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1789301, Length=81, Percent_Identity=43.2098765432099, Blast_Score=72, Evalue=6e-15,
Organism=Escherichia coli, GI1790027, Length=77, Percent_Identity=40.2597402597403, Blast_Score=64, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004718 [H]

Pfam domain/function: PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 10761; Mature: 10630

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIKGEDIHKLVVACDAGMGSSVMLASQLRKQLKAYAVTVEHTPVNSIPADADLVVCHV
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEEEC
GLADRARRGVPDKPIVTFQVFIGDPAVANVLAAIREGKVLDV
CCHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCEECC
>Mature Secondary Structure 
ATIKGEDIHKLVVACDAGMGSSVMLASQLRKQLKAYAVTVEHTPVNSIPADADLVVCHV
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEEEC
GLADRARRGVPDKPIVTFQVFIGDPAVANVLAAIREGKVLDV
CCHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]