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The map label for this gene is mtlA [H]

Identifier: 158318801

GI number: 158318801

Start: 8631891

End: 8633066

Strand: Reverse

Name: mtlA [H]

Synonym: Franean1_7073

Alternate gene names: 158318801

Gene position: 8633066-8631891 (Counterclockwise)

Preceding gene: 158318802

Following gene: 158318800

Centisome position: 96.11

GC content: 66.16

Gene sequence:

>1176_bases
ATGACTACCGCCTATACGCCGGCCGTGTACGGTACGGGCGTCAAGGCCGCGATCCAACGTATCGGCGGCTATCTGGCCGG
GATGGTAATGCCCAACATCGGGGCCTTCATCGCCTGGGGTTTAATCACCGCGCTGTTTATCCCGACCGGATGGTTACCGA
ACGAGACACTGGCTGAGCTGGTGGGGCCGATCATCACGGTGCTGCTGCCGGTTCTCATCGGCTACACGGGCGGCCGTATG
GTCCACGGCCAGCGCGGCGCGGTCATCGGCGCGATCGCGACGATGGGTCTGGTGGTCGGGTCCGACGTGCCGATGTTCCT
CGGCGCAATGATGGTGGGGCCGTTGGCGGGCGCACTGGTCAAGGGATTCGACCGGCTCACGAAGGAGCGGATACGGGCCG
GATTCGAAATGCTGGTGGAGAACTTCTCCGCCGGGATCATCGGCGCCGGCATGGCAGTCCTCGGCGTGTGGGTCATCGGG
CCGGTCGTGGAGTGGTTCACCGAACGCGCTGGCGACGCCGTGCAATGGCTGGTGGACCACAGCGTCCTGCCGCTCACTGC
GCTCATCATCGAGCCGGCCAAGGTGCTCTTCCTGAACAACGCGATCAACCACGGTGTGCTCGGGACGCTGGGGGTGGCGG
AGGCCGCGGAGAAGGGCCAGTCCGTCCTGTTCATGCTTGAGTCGAACCCGGGGCCGGGCCTCGGCCTGCTGGTCGCCTAC
TTCCTCTTCGGGCCGCGCCAGCTGCGCCCGAGTGTCCCGGCGGCTATGATCATCCATTTCCTCGGTGGCATCCATGAGAT
CTACTTCCCGTACGTGCTCATGAAGCCGCGCCTGATCCTGGCCACCATCGCCGGGAGCGCTTCGGGAATTCTGGTCTTTA
TCGCCACCGACGCCGGCCTGGTCGCCACCCCGTCGCCCGGAAGCATCTTCGCCTACATCGCCGGGACGCCGCAGGGCAGC
TGGTTCGGGGTCTTTGCAGGGGTGCTCGTGTCCGCTGCGGTGTCCTTCGCGGTCGCTTCCGTCCTGCTCGGATTCGGTCG
GCTGGAAAAAGGCGAGGACCCGGTTGAAGCGGACGGCGCCGATCCGGGCAGTACGAGCGAGGGGAAGGTTTCCAGCGGCG
CGGCTAGCCCGGTGACAGCAGCCTCGCAGCGGCTTTCCGCAGCATCGGAAGGGTGA

Upstream 100 bases:

>100_bases
TCCGGCTTTATCCCTGTCGAATTTTTCCCTATTTCTTGATATTTTCACCGCCCCGCACTTGCGTCCGGGGTGCGCGTCCG
ACGAAGGAGTTCAAAAAAAC

Downstream 100 bases:

>100_bases
TGGCATATGGCAACCATCAAGGGTGAGGACATCCACAAGCTCGTTGTCGCCTGCGACGCGGGAATGGGAAGCAGCGTGAT
GCTGGCCAGCCAGCTCCGCA

Product: PTS system, mannitol-specific IIC subunit

Products: NA

Alternate protein names: EIICB-Mtl; EII-Mtl; Mannitol permease IIC component; PTS system mannitol-specific EIIC component; Mannitol-specific phosphotransferase enzyme IIB component; PTS system mannitol-specific EIIB component [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTTAYTPAVYGTGVKAAIQRIGGYLAGMVMPNIGAFIAWGLITALFIPTGWLPNETLAELVGPIITVLLPVLIGYTGGRM
VHGQRGAVIGAIATMGLVVGSDVPMFLGAMMVGPLAGALVKGFDRLTKERIRAGFEMLVENFSAGIIGAGMAVLGVWVIG
PVVEWFTERAGDAVQWLVDHSVLPLTALIIEPAKVLFLNNAINHGVLGTLGVAEAAEKGQSVLFMLESNPGPGLGLLVAY
FLFGPRQLRPSVPAAMIIHFLGGIHEIYFPYVLMKPRLILATIAGSASGILVFIATDAGLVATPSPGSIFAYIAGTPQGS
WFGVFAGVLVSAAVSFAVASVLLGFGRLEKGEDPVEADGADPGSTSEGKVSSGAASPVTAASQRLSAASEG

Sequences:

>Translated_391_residues
MTTAYTPAVYGTGVKAAIQRIGGYLAGMVMPNIGAFIAWGLITALFIPTGWLPNETLAELVGPIITVLLPVLIGYTGGRM
VHGQRGAVIGAIATMGLVVGSDVPMFLGAMMVGPLAGALVKGFDRLTKERIRAGFEMLVENFSAGIIGAGMAVLGVWVIG
PVVEWFTERAGDAVQWLVDHSVLPLTALIIEPAKVLFLNNAINHGVLGTLGVAEAAEKGQSVLFMLESNPGPGLGLLVAY
FLFGPRQLRPSVPAAMIIHFLGGIHEIYFPYVLMKPRLILATIAGSASGILVFIATDAGLVATPSPGSIFAYIAGTPQGS
WFGVFAGVLVSAAVSFAVASVLLGFGRLEKGEDPVEADGADPGSTSEGKVSSGAASPVTAASQRLSAASEG
>Mature_390_residues
TTAYTPAVYGTGVKAAIQRIGGYLAGMVMPNIGAFIAWGLITALFIPTGWLPNETLAELVGPIITVLLPVLIGYTGGRMV
HGQRGAVIGAIATMGLVVGSDVPMFLGAMMVGPLAGALVKGFDRLTKERIRAGFEMLVENFSAGIIGAGMAVLGVWVIGP
VVEWFTERAGDAVQWLVDHSVLPLTALIIEPAKVLFLNNAINHGVLGTLGVAEAAEKGQSVLFMLESNPGPGLGLLVAYF
LFGPRQLRPSVPAAMIIHFLGGIHEIYFPYVLMKPRLILATIAGSASGILVFIATDAGLVATPSPGSIFAYIAGTPQGSW
FGVFAGVLVSAAVSFAVASVLLGFGRLEKGEDPVEADGADPGSTSEGKVSSGAASPVTAASQRLSAASEG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2213

COG function: function code G; Phosphotransferase system, mannitol-specific IIBC component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790027, Length=369, Percent_Identity=54.7425474254742, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1789301, Length=358, Percent_Identity=55.3072625698324, Blast_Score=378, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004718 [H]

Pfam domain/function: PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 40201; Mature: 40069

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAYTPAVYGTGVKAAIQRIGGYLAGMVMPNIGAFIAWGLITALFIPTGWLPNETLAEL
CCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VGPIITVLLPVLIGYTGGRMVHGQRGAVIGAIATMGLVVGSDVPMFLGAMMVGPLAGALV
HHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KGFDRLTKERIRAGFEMLVENFSAGIIGAGMAVLGVWVIGPVVEWFTERAGDAVQWLVDH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
SVLPLTALIIEPAKVLFLNNAINHGVLGTLGVAEAAEKGQSVLFMLESNPGPGLGLLVAY
CHHHHHHHHHCCHHHEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHH
FLFGPRQLRPSVPAAMIIHFLGGIHEIYFPYVLMKPRLILATIAGSASGILVFIATDAGL
HHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCE
VATPSPGSIFAYIAGTPQGSWFGVFAGVLVSAAVSFAVASVLLGFGRLEKGEDPVEADGA
EECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DPGSTSEGKVSSGAASPVTAASQRLSAASEG
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTAYTPAVYGTGVKAAIQRIGGYLAGMVMPNIGAFIAWGLITALFIPTGWLPNETLAEL
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VGPIITVLLPVLIGYTGGRMVHGQRGAVIGAIATMGLVVGSDVPMFLGAMMVGPLAGALV
HHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KGFDRLTKERIRAGFEMLVENFSAGIIGAGMAVLGVWVIGPVVEWFTERAGDAVQWLVDH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
SVLPLTALIIEPAKVLFLNNAINHGVLGTLGVAEAAEKGQSVLFMLESNPGPGLGLLVAY
CHHHHHHHHHCCHHHEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHH
FLFGPRQLRPSVPAAMIIHFLGGIHEIYFPYVLMKPRLILATIAGSASGILVFIATDAGL
HHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCE
VATPSPGSIFAYIAGTPQGSWFGVFAGVLVSAAVSFAVASVLLGFGRLEKGEDPVEADGA
EECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DPGSTSEGKVSSGAASPVTAASQRLSAASEG
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8824601 [H]