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The map label for this gene is galE [H]

Identifier: 158318296

GI number: 158318296

Start: 7980567

End: 7981616

Strand: Direct

Name: galE [H]

Synonym: Franean1_6561

Alternate gene names: 158318296

Gene position: 7980567-7981616 (Clockwise)

Preceding gene: 158318295

Following gene: 158318297

Centisome position: 88.85

GC content: 66.0

Gene sequence:

>1050_bases
ATGCGCATTCTTGTGACCGGACACGACGGATATATAGGAACCCGCCTCGTCCCGTTCCTCCGGCAAGCCGGCCATGACGT
CGCCGGCCTGGACAGCATGCTGTTCTCCGACTGCACGCTCGGGACCGAACCGGACTCCGTGCCGGCGCTCGCCCTCGACA
TCCGCGACGTCCGCCCCTCCCATCTGGAGGGGTTCGACGCCGTGATTCATCTGGCCGGAATCTCCAACGACCCACTGGGA
GATCTCAATCCCCGCACCACCTACGACATCAATGCACGCGGGACGTTGATGATCGGCAGCGCGGCCAGGCAGGCCGGCGT
GCCGCGATTCGTCTTCTCGTCCTCCTGTAGCCTTTATGGCGCCCATGGGGACGCCCCCATCGACGAATCCGCCGAGTTCC
ATCCGGTGACGCCGTACGGGGAGTCGAAGGTGATCGCCGAACGCGAGCTCACCGCGCTCGCCGACGATGGTTTCAGTCCG
GTCTTCCTCCGCAACGCGACCGCCTACGGGGTGTCACCCAGACTGCGCGGCGACCTGGTGGTCAACAACCTGACGGGATA
TGCGGTCACGACCGGCAAGGTGTACCTCAAGAGCGACGGGACGCCATGGCGTCCGCTGGTCCACATCGAGGACATCGCCC
GGGCGATGCTCGCGGTCTGCGAGGCACCGCGGGAGGCGATCCATTGCAAGGCGTTCAACGTCGGCCGGTCGGGCGAGAAC
TACCGGATACGTGAGGTCGCCGAGATCGTCGAGGATGTCGTACCTGGCAGCCGGGTTGTCTTCGCCGACGAGGCCGGACC
GGACAAGCGGAACTATCGGGTCGATTGCGACCGCATCGCACGGGAGATACCCGGATTCCAGCCGGTGTGGACGGTGCGCA
AGGGCGTGGAGGAGCTGCACGCCGCCTACCTGGCAGCCGAGCTGGCCAAGGAGGACCTGATCGGGGCGCGCTTCCAGCGG
ATCCGGCGCATCCAGGAGCTCATGGCGGAAGGTCTACTCGACAACTCCCTGCGGCCGATCAGAAGGGAGCGGGTGCCATG
CGCGACCTGA

Upstream 100 bases:

>100_bases
GCGGATTCTGGCAGTGCATGGACACGGTACGCGACCGAAAACTCCTACAGTCGCTGTGGGACACCGGCGACGCGCCATGG
AAGGTGTGGGACTGAGCCCG

Downstream 100 bases:

>100_bases
TCGTATGTCGGTCCTGCGGCGCGGCTGAGCTGAAGGACTTCCTGTCGCTGGGAACGACACCACTCGCCGACGCGCTGGTC
CCGGCGGACGCTCTCGACCG

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MRILVTGHDGYIGTRLVPFLRQAGHDVAGLDSMLFSDCTLGTEPDSVPALALDIRDVRPSHLEGFDAVIHLAGISNDPLG
DLNPRTTYDINARGTLMIGSAARQAGVPRFVFSSSCSLYGAHGDAPIDESAEFHPVTPYGESKVIAERELTALADDGFSP
VFLRNATAYGVSPRLRGDLVVNNLTGYAVTTGKVYLKSDGTPWRPLVHIEDIARAMLAVCEAPREAIHCKAFNVGRSGEN
YRIREVAEIVEDVVPGSRVVFADEAGPDKRNYRVDCDRIAREIPGFQPVWTVRKGVEELHAAYLAAELAKEDLIGARFQR
IRRIQELMAEGLLDNSLRPIRRERVPCAT

Sequences:

>Translated_349_residues
MRILVTGHDGYIGTRLVPFLRQAGHDVAGLDSMLFSDCTLGTEPDSVPALALDIRDVRPSHLEGFDAVIHLAGISNDPLG
DLNPRTTYDINARGTLMIGSAARQAGVPRFVFSSSCSLYGAHGDAPIDESAEFHPVTPYGESKVIAERELTALADDGFSP
VFLRNATAYGVSPRLRGDLVVNNLTGYAVTTGKVYLKSDGTPWRPLVHIEDIARAMLAVCEAPREAIHCKAFNVGRSGEN
YRIREVAEIVEDVVPGSRVVFADEAGPDKRNYRVDCDRIAREIPGFQPVWTVRKGVEELHAAYLAAELAKEDLIGARFQR
IRRIQELMAEGLLDNSLRPIRRERVPCAT
>Mature_349_residues
MRILVTGHDGYIGTRLVPFLRQAGHDVAGLDSMLFSDCTLGTEPDSVPALALDIRDVRPSHLEGFDAVIHLAGISNDPLG
DLNPRTTYDINARGTLMIGSAARQAGVPRFVFSSSCSLYGAHGDAPIDESAEFHPVTPYGESKVIAERELTALADDGFSP
VFLRNATAYGVSPRLRGDLVVNNLTGYAVTTGKVYLKSDGTPWRPLVHIEDIARAMLAVCEAPREAIHCKAFNVGRSGEN
YRIREVAEIVEDVVPGSRVVFADEAGPDKRNYRVDCDRIAREIPGFQPVWTVRKGVEELHAAYLAAELAKEDLIGARFQR
IRRIQELMAEGLLDNSLRPIRRERVPCAT

Specific function: Galactose metabolism; third step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=286, Percent_Identity=29.3706293706294, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI56118217, Length=286, Percent_Identity=29.3706293706294, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI189083684, Length=286, Percent_Identity=29.3706293706294, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI42516563, Length=308, Percent_Identity=25.3246753246753, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI7657641, Length=261, Percent_Identity=24.1379310344828, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786974, Length=333, Percent_Identity=30.6306306306306, Blast_Score=101, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17539532, Length=291, Percent_Identity=25.4295532646048, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=286, Percent_Identity=30.0699300699301, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356223, Length=329, Percent_Identity=26.4437689969605, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38232; Mature: 38232

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVTGHDGYIGTRLVPFLRQAGHDVAGLDSMLFSDCTLGTEPDSVPALALDIRDVRPS
CEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCC
HLEGFDAVIHLAGISNDPLGDLNPRTTYDINARGTLMIGSAARQAGVPRFVFSSSCSLYG
CCCCHHHEEEEECCCCCCCCCCCCCCEEEECCCCEEEECCHHHHCCCCEEEECCCCEEEE
AHGDAPIDESAEFHPVTPYGESKVIAERELTALADDGFSPVFLRNATAYGVSPRLRGDLV
CCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEEEECCEEECCCCCCCCCEE
VNNLTGYAVTTGKVYLKSDGTPWRPLVHIEDIARAMLAVCEAPREAIHCKAFNVGRSGEN
EECCCCEEEEECEEEEECCCCCCCCEEEHHHHHHHHHHHHHCHHHHEEEEEEECCCCCCC
YRIREVAEIVEDVVPGSRVVFADEAGPDKRNYRVDCDRIAREIPGFQPVWTVRKGVEELH
CHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEECHHHHHHHCCCCCHHHHHHHHHHHHH
AAYLAAELAKEDLIGARFQRIRRIQELMAEGLLDNSLRPIRRERVPCAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MRILVTGHDGYIGTRLVPFLRQAGHDVAGLDSMLFSDCTLGTEPDSVPALALDIRDVRPS
CEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCC
HLEGFDAVIHLAGISNDPLGDLNPRTTYDINARGTLMIGSAARQAGVPRFVFSSSCSLYG
CCCCHHHEEEEECCCCCCCCCCCCCCEEEECCCCEEEECCHHHHCCCCEEEECCCCEEEE
AHGDAPIDESAEFHPVTPYGESKVIAERELTALADDGFSPVFLRNATAYGVSPRLRGDLV
CCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEEEECCEEECCCCCCCCCEE
VNNLTGYAVTTGKVYLKSDGTPWRPLVHIEDIARAMLAVCEAPREAIHCKAFNVGRSGEN
EECCCCEEEEECEEEEECCCCCCCCEEEHHHHHHHHHHHHHCHHHHEEEEEEECCCCCCC
YRIREVAEIVEDVVPGSRVVFADEAGPDKRNYRVDCDRIAREIPGFQPVWTVRKGVEELH
CHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEECHHHHHHHCCCCCHHHHHHHHHHHHH
AAYLAAELAKEDLIGARFQRIRRIQELMAEGLLDNSLRPIRRERVPCAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]