Click here to switch to the map view.

The map label for this gene is rfbF [H]

Identifier: 158318295

GI number: 158318295

Start: 7979788

End: 7980561

Strand: Direct

Name: rfbF [H]

Synonym: Franean1_6560

Alternate gene names: 158318295

Gene position: 7979788-7980561 (Clockwise)

Preceding gene: 158318294

Following gene: 158318296

Centisome position: 88.84

GC content: 64.08

Gene sequence:

>774_bases
ATGAAGGTCGGAATTCTGGCCGGCGGTTTGGGAAGCCGGTTGGCGGAAGAGACTGTCATCAAGCCCAAGCCAATGATCGA
AATCGGCAACCACCCGATCATCTGGCACATCATGAAGCATTACGCCCACTATAAGATCACCGACTTCACCGTCGCCCTGG
GTTACAAGGGAGAGCACATCAAGCGCTGGCTGGTCGACTACGCCGCGCTCACCAGCGACCTCACGGTCGAACTCCGGCAC
GGGCAGGTCCACCGGCACGCGAGCAGTCCTGAGGACTGGCGGGTCAACCTCGTCGACACCGGCCAGGATACGGCCACCGG
CGGCCGTATCCTGCGGCTCGAGCGCTGGCTCGGCGACTCCGGGACGTTCATGTTGACCTGGGGGGACGGCGTCTCCAACC
TCGACCTCGACGCGCTGCTCGCGTTTCACCGTGGCCATGGGAAGATCGCCACTCTGACCGCCGTCCGGCCACCGGCCCGC
TTCGGTCGCCTGGAGCTGGAGGGTGACCGGGTCTCGGAGTTCTCCGAGAAACCTCAGGCCGGCGAGGGCTGGATCAACGG
CGCCTTCTTCGTGCTGGAGCCGCAGGTTTTCAACTATATCGCCGGCGACGCCACGCAGTTCGAGAAGGAGCCCCTCGAGC
TGCTCGCCAAGGACGGCGAGCTGATGGCATACCGCCACAGCGGATTCTGGCAGTGCATGGACACGGTACGCGACCGAAAA
CTCCTACAGTCGCTGTGGGACACCGGCGACGCGCCATGGAAGGTGTGGGACTGA

Upstream 100 bases:

>100_bases
CGCCGTGCCACCAGCCACCGTTGAACCGCCGCGGCCGCGCTAGGGTACCAGAAGAATAACCTTCGACGGCCGCGACCATC
ACCAATTGGCGGGGAAAACA

Downstream 100 bases:

>100_bases
GCCCGATGCGCATTCTTGTGACCGGACACGACGGATATATAGGAACCCGCCTCGTCCCGTTCCTCCGGCAAGCCGGCCAT
GACGTCGCCGGCCTGGACAG

Product: glucose-1-phosphate cytidylyltransferase

Products: NA

Alternate protein names: CDP-glucose pyrophosphorylase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKVGILAGGLGSRLAEETVIKPKPMIEIGNHPIIWHIMKHYAHYKITDFTVALGYKGEHIKRWLVDYAALTSDLTVELRH
GQVHRHASSPEDWRVNLVDTGQDTATGGRILRLERWLGDSGTFMLTWGDGVSNLDLDALLAFHRGHGKIATLTAVRPPAR
FGRLELEGDRVSEFSEKPQAGEGWINGAFFVLEPQVFNYIAGDATQFEKEPLELLAKDGELMAYRHSGFWQCMDTVRDRK
LLQSLWDTGDAPWKVWD

Sequences:

>Translated_257_residues
MKVGILAGGLGSRLAEETVIKPKPMIEIGNHPIIWHIMKHYAHYKITDFTVALGYKGEHIKRWLVDYAALTSDLTVELRH
GQVHRHASSPEDWRVNLVDTGQDTATGGRILRLERWLGDSGTFMLTWGDGVSNLDLDALLAFHRGHGKIATLTAVRPPAR
FGRLELEGDRVSEFSEKPQAGEGWINGAFFVLEPQVFNYIAGDATQFEKEPLELLAKDGELMAYRHSGFWQCMDTVRDRK
LLQSLWDTGDAPWKVWD
>Mature_257_residues
MKVGILAGGLGSRLAEETVIKPKPMIEIGNHPIIWHIMKHYAHYKITDFTVALGYKGEHIKRWLVDYAALTSDLTVELRH
GQVHRHASSPEDWRVNLVDTGQDTATGGRILRLERWLGDSGTFMLTWGDGVSNLDLDALLAFHRGHGKIATLTAVRPPAR
FGRLELEGDRVSEFSEKPQAGEGWINGAFFVLEPQVFNYIAGDATQFEKEPLELLAKDGELMAYRHSGFWQCMDTVRDRK
LLQSLWDTGDAPWKVWD

Specific function: Involved in the biosynthesis of the tyvelose, a 3,6- dideoxyhexose found in the O-antigen of the surface lipopolysaccharides. It catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate. This enzyme can utilize either CTP or UTP as the nucle

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate cytidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=252, Percent_Identity=26.984126984127, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI11761619, Length=252, Percent_Identity=26.984126984127, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI133931050, Length=251, Percent_Identity=25.8964143426295, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320148, Length=253, Percent_Identity=28.0632411067194, Blast_Score=93, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013446
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.33 [H]

Molecular weight: Translated: 29019; Mature: 29019

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGILAGGLGSRLAEETVIKPKPMIEIGNHPIIWHIMKHYAHYKITDFTVALGYKGEHI
CEEEEEECCHHHHHHHHHCCCCCCCEEECCCCEEHHHHHHHHCEEEEEEEEEECCCCHHH
KRWLVDYAALTSDLTVELRHGQVHRHASSPEDWRVNLVDTGQDTATGGRILRLERWLGDS
HHHHHHHHHHCCCEEEEEECCEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCC
GTFMLTWGDGVSNLDLDALLAFHRGHGKIATLTAVRPPARFGRLELEGDRVSEFSEKPQA
CCEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEEECCCHHHCEEEECCCHHHHHHCCCCC
GEGWINGAFFVLEPQVFNYIAGDATQFEKEPLELLAKDGELMAYRHSGFWQCMDTVRDRK
CCCCCCCEEEEECHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
LLQSLWDTGDAPWKVWD
HHHHHHCCCCCCEEECC
>Mature Secondary Structure
MKVGILAGGLGSRLAEETVIKPKPMIEIGNHPIIWHIMKHYAHYKITDFTVALGYKGEHI
CEEEEEECCHHHHHHHHHCCCCCCCEEECCCCEEHHHHHHHHCEEEEEEEEEECCCCHHH
KRWLVDYAALTSDLTVELRHGQVHRHASSPEDWRVNLVDTGQDTATGGRILRLERWLGDS
HHHHHHHHHHCCCEEEEEECCEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCC
GTFMLTWGDGVSNLDLDALLAFHRGHGKIATLTAVRPPARFGRLELEGDRVSEFSEKPQA
CCEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEEECCCHHHCEEEECCCHHHHHHCCCCC
GEGWINGAFFVLEPQVFNYIAGDATQFEKEPLELLAKDGELMAYRHSGFWQCMDTVRDRK
CCCCCCCEEEEECHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHH
LLQSLWDTGDAPWKVWD
HHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]