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The map label for this gene is tadA [H]

Identifier: 158318268

GI number: 158318268

Start: 7944126

End: 7944683

Strand: Direct

Name: tadA [H]

Synonym: Franean1_6533

Alternate gene names: 158318268

Gene position: 7944126-7944683 (Clockwise)

Preceding gene: 158318267

Following gene: 158318269

Centisome position: 88.44

GC content: 77.96

Gene sequence:

>558_bases
GTGGCTGACACCCGCTCACCGGTGTCTGCCACCGGCCCGCCGGTGACGGTCACCCGCGCACCGGTGACGGACGGCTACCG
CGAGGCGATGGGCCTCGCCCTGGCCGAGGCCGATCTCGCCCGGGCCGCCGGGGACGTCCCGGTCGGCGCGGTCGTCGTGG
CGGCGGACGGGGCGGTGCTCGGCCGCGGCCACAACGCGCGCGAGGCCGCCGGCGACCCGACCGCCCACGCCGAGGTCGTC
GCGCTGCGCCAGGCCGCGGCCCGGCTGGGTTCCTGGCGCCTGACCGGGGCGACCCTCGTGGTCACCCTGGAGCCGTGCAC
CATGTGCGCCGGGGCCCTCGTCCTCGCCCGGGTGGACCGGCTCGTCTACGGCGCCGTGGACGACAAGGCCGGCGCTGTGG
GCTCCCTGTGGGACGTCGTCCGCGACCGGCGGTTGAACCACCGCCCCGAGGTCGTCGCGGGCGTCCGCGGGCAGGAGTGC
TCGGAGCAGCTCGCCGCCTTCTTCGCCGACCGGCGGACGCAACGCCGCGACGCACGCCGTCCGCGCACCCCCGACTAA

Upstream 100 bases:

>100_bases
GCGCTGCTGGAGCTGATCGCCGAGGAGGGCATGCTGCCCGCCGACGTGATCAGCGCGGTCAGCGAGCGGGCCGGCGCCGG
GGAGATCTTCGACGAGGTCC

Downstream 100 bases:

>100_bases
CCGGACCAGGACGACGTCGCGTAAGCTAGCCCGCGGTGGAGTCGCCTAGTGGCCGAGGGCGCACGCCTCGAAAGCGTGTG
AGGGGGCAACCCCTCCGTGG

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MADTRSPVSATGPPVTVTRAPVTDGYREAMGLALAEADLARAAGDVPVGAVVVAADGAVLGRGHNAREAAGDPTAHAEVV
ALRQAAARLGSWRLTGATLVVTLEPCTMCAGALVLARVDRLVYGAVDDKAGAVGSLWDVVRDRRLNHRPEVVAGVRGQEC
SEQLAAFFADRRTQRRDARRPRTPD

Sequences:

>Translated_185_residues
MADTRSPVSATGPPVTVTRAPVTDGYREAMGLALAEADLARAAGDVPVGAVVVAADGAVLGRGHNAREAAGDPTAHAEVV
ALRQAAARLGSWRLTGATLVVTLEPCTMCAGALVLARVDRLVYGAVDDKAGAVGSLWDVVRDRRLNHRPEVVAGVRGQEC
SEQLAAFFADRRTQRRDARRPRTPD
>Mature_184_residues
ADTRSPVSATGPPVTVTRAPVTDGYREAMGLALAEADLARAAGDVPVGAVVVAADGAVLGRGHNAREAAGDPTAHAEVVA
LRQAAARLGSWRLTGATLVVTLEPCTMCAGALVLARVDRLVYGAVDDKAGAVGSLWDVVRDRRLNHRPEVVAGVRGQECS
EQLAAFFADRRTQRRDARRPRTPD

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=151, Percent_Identity=31.7880794701987, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI145693172, Length=164, Percent_Identity=42.6829268292683, Blast_Score=125, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17555996, Length=143, Percent_Identity=35.6643356643357, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17554608, Length=108, Percent_Identity=43.5185185185185, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17541138, Length=155, Percent_Identity=32.9032258064516, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325319, Length=147, Percent_Identity=32.6530612244898, Blast_Score=76, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=37.2413793103448, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19385; Mature: 19254

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTRSPVSATGPPVTVTRAPVTDGYREAMGLALAEADLARAAGDVPVGAVVVAADGAVL
CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEE
GRGHNAREAAGDPTAHAEVVALRQAAARLGSWRLTGATLVVTLEPCTMCAGALVLARVDR
ECCCCCHHCCCCCCHHHHHHHHHHHHHHHCCEEECCEEEEEEECHHHHHHHHHHHHHHHH
LVYGAVDDKAGAVGSLWDVVRDRRLNHRPEVVAGVRGQECSEQLAAFFADRRTQRRDARR
HHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
PRTPD
CCCCC
>Mature Secondary Structure 
ADTRSPVSATGPPVTVTRAPVTDGYREAMGLALAEADLARAAGDVPVGAVVVAADGAVL
CCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEE
GRGHNAREAAGDPTAHAEVVALRQAAARLGSWRLTGATLVVTLEPCTMCAGALVLARVDR
ECCCCCHHCCCCCCHHHHHHHHHHHHHHHCCEEECCEEEEEEECHHHHHHHHHHHHHHHH
LVYGAVDDKAGAVGSLWDVVRDRRLNHRPEVVAGVRGQECSEQLAAFFADRRTQRRDARR
HHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
PRTPD
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]