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The map label for this gene is pksS [H]

Identifier: 158318069

GI number: 158318069

Start: 7686876

End: 7688147

Strand: Direct

Name: pksS [H]

Synonym: Franean1_6329

Alternate gene names: 158318069

Gene position: 7686876-7688147 (Clockwise)

Preceding gene: 158318068

Following gene: 158318070

Centisome position: 85.58

GC content: 70.52

Gene sequence:

>1272_bases
ATGCCGGTACAGACGATGGACTTCGCCGCTCCGTCCTTCCGGACGGATCCGTTCCCGGCCTGGTCCGACCTGCGCCGGGC
CGGGCCGCTGCACCGGGACGTCAGCGGTGCGTGGATCGTCGTGAGCCACCGGGAGGTCGGCCGGCTGCTCGCTGATCCGC
GAGTGGGCAAGGACCTCCGTCGGCTGAGTACCTACGGGGCGCAACGTCCCTATGGCCCGGACGGGCTCGCCGAGTACTAC
ATCGAGCAGTGGATGGAGTGCCGGCTCCCGACGATGCACCGGCGATGGCGTCAGCTGGTCCTGCCTGGATTCACCCACCG
GGCGGTCCACGGCCTGCGAGCCGAGCTGTGCCGGACCGCCGACGACCTTCTCACCCACGCGCTCACCCACGCGCCGTCCG
ACGGACAGGTCGATCTCCTGCGGGACTTCGCCAGACCGTTCCCGGTCGCCGTGATCGTCCGGGTCCTCGGGCTGACGGAC
CTGGACACCGACCGGCTGGCGCAGCTGTCCCGAACGATCGCGGCGGTCCTGGAACCTAACGCCGCCGTGTCGGCGCGGGA
GGCCGGTGACGCGGCCCTGGCGGAACTCGCCGGACTGCTGTGGGACGCGGTGCGGGCGGACCGGGGCCCGCACCCCGACG
GATTCCTGCGCCGACTCGTCGACGCGAACAAGGGCCTGCTGAGCCCCGAGCAGCTGATCGCCACGGTACTGCTGTTGTTC
CTGTCCGGGAACGACACGATCACGGGCCTGATCGCCAACGGGGTGCTTGCGCTCGCCAGTGTCCCCGACCAGGCTGACCG
ACTGCGCGCGCATCCTGAACTGCTTCCGATGGCGGTCGAGGAGGTTCTGCGGTTCGACGCGCCCGCCTGCGTCGCGGTCC
GGACGACCTACGAGCCGATGACGATCGACGGCGTCACCGTCGAGCGCGGTGCCGCGCTGCTCCTGGCGATCAGCTCCGCC
AACCGTGACCCGGCGGCCTTCGCCGAGCCCGACGTCTTCCGTGTCGACCGGCGCCCGATCCGGCATTTCGCGTTCGGCTC
GGGCGACCACACCTGCGTCGGGATCGGCCTCGCCCGGATGGAGGCGACGATCGCGCTCGAAGCGCTCCTGCACCGTTTTC
CCCGGTTGACCCACGACCCATCGACCCTGCGGTGGAGCGATGCTCTTTACCTGCGTTCTCCGGAGAACCTGGTACTCCTG
TGCACTGTGCCGCCGGCCCCCGAGCGGGCCTGTGGGGTGCCAGAAGTCGGCCTGGGTCGTGACCTGGGGTGA

Upstream 100 bases:

>100_bases
CTGCCAGGCCCTGGCCGACCAGCCGTCCTCGCGGTCGCCCGGACGGGCGCCTGAGGGCCGGCCCGGATGACATCGACATC
CCGTCGCGGAGGAGGCACAG

Downstream 100 bases:

>100_bases
TGCGACGACGCAGGGCCGATGGGATGATGGTCAGCGTGCTGCGCCACGAGGTCGCCGTGCTGCGCCGCACCCAGCCCAAG
CCCCAGGCGGCGGGTCGCCC

Product: cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MPVQTMDFAAPSFRTDPFPAWSDLRRAGPLHRDVSGAWIVVSHREVGRLLADPRVGKDLRRLSTYGAQRPYGPDGLAEYY
IEQWMECRLPTMHRRWRQLVLPGFTHRAVHGLRAELCRTADDLLTHALTHAPSDGQVDLLRDFARPFPVAVIVRVLGLTD
LDTDRLAQLSRTIAAVLEPNAAVSAREAGDAALAELAGLLWDAVRADRGPHPDGFLRRLVDANKGLLSPEQLIATVLLLF
LSGNDTITGLIANGVLALASVPDQADRLRAHPELLPMAVEEVLRFDAPACVAVRTTYEPMTIDGVTVERGAALLLAISSA
NRDPAAFAEPDVFRVDRRPIRHFAFGSGDHTCVGIGLARMEATIALEALLHRFPRLTHDPSTLRWSDALYLRSPENLVLL
CTVPPAPERACGVPEVGLGRDLG

Sequences:

>Translated_423_residues
MPVQTMDFAAPSFRTDPFPAWSDLRRAGPLHRDVSGAWIVVSHREVGRLLADPRVGKDLRRLSTYGAQRPYGPDGLAEYY
IEQWMECRLPTMHRRWRQLVLPGFTHRAVHGLRAELCRTADDLLTHALTHAPSDGQVDLLRDFARPFPVAVIVRVLGLTD
LDTDRLAQLSRTIAAVLEPNAAVSAREAGDAALAELAGLLWDAVRADRGPHPDGFLRRLVDANKGLLSPEQLIATVLLLF
LSGNDTITGLIANGVLALASVPDQADRLRAHPELLPMAVEEVLRFDAPACVAVRTTYEPMTIDGVTVERGAALLLAISSA
NRDPAAFAEPDVFRVDRRPIRHFAFGSGDHTCVGIGLARMEATIALEALLHRFPRLTHDPSTLRWSDALYLRSPENLVLL
CTVPPAPERACGVPEVGLGRDLG
>Mature_422_residues
PVQTMDFAAPSFRTDPFPAWSDLRRAGPLHRDVSGAWIVVSHREVGRLLADPRVGKDLRRLSTYGAQRPYGPDGLAEYYI
EQWMECRLPTMHRRWRQLVLPGFTHRAVHGLRAELCRTADDLLTHALTHAPSDGQVDLLRDFARPFPVAVIVRVLGLTDL
DTDRLAQLSRTIAAVLEPNAAVSAREAGDAALAELAGLLWDAVRADRGPHPDGFLRRLVDANKGLLSPEQLIATVLLLFL
SGNDTITGLIANGVLALASVPDQADRLRAHPELLPMAVEEVLRFDAPACVAVRTTYEPMTIDGVTVERGAALLLAISSAN
RDPAAFAEPDVFRVDRRPIRHFAFGSGDHTCVGIGLARMEATIALEALLHRFPRLTHDPSTLRWSDALYLRSPENLVLLC
TVPPAPERACGVPEVGLGRDLG

Specific function: Involved in the metabolism of the antibiotic polyketide bacillaene which is involved in secondary metabolism. The substrate is dihydrobacillaene [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI13435386, Length=410, Percent_Identity=22.1951219512195, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI5729796, Length=418, Percent_Identity=23.9234449760766, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 46311; Mature: 46180

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVQTMDFAAPSFRTDPFPAWSDLRRAGPLHRDVSGAWIVVSHREVGRLLADPRVGKDLR
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEECHHHHHHHCCCCCCHHHH
RLSTYGAQRPYGPDGLAEYYIEQWMECRLPTMHRRWRQLVLPGFTHRAVHGLRAELCRTA
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
DDLLTHALTHAPSDGQVDLLRDFARPFPVAVIVRVLGLTDLDTDRLAQLSRTIAAVLEPN
HHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
AAVSAREAGDAALAELAGLLWDAVRADRGPHPDGFLRRLVDANKGLLSPEQLIATVLLLF
CCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LSGNDTITGLIANGVLALASVPDQADRLRAHPELLPMAVEEVLRFDAPACVAVRTTYEPM
HCCCCCEEHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCE
TIDGVTVERGAALLLAISSANRDPAAFAEPDVFRVDRRPIRHFAFGSGDHTCVGIGLARM
EECCEEECCCCEEEEEEECCCCCCCCCCCCCCEECCCCHHHHHCCCCCCCEEEEHHHHHH
EATIALEALLHRFPRLTHDPSTLRWSDALYLRSPENLVLLCTVPPAPERACGVPEVGLGR
HHHHHHHHHHHHCCCCCCCCCCEEECCEEEEECCCCEEEEEECCCCCHHHCCCCCCCCCC
DLG
CCC
>Mature Secondary Structure 
PVQTMDFAAPSFRTDPFPAWSDLRRAGPLHRDVSGAWIVVSHREVGRLLADPRVGKDLR
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEECHHHHHHHCCCCCCHHHH
RLSTYGAQRPYGPDGLAEYYIEQWMECRLPTMHRRWRQLVLPGFTHRAVHGLRAELCRTA
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
DDLLTHALTHAPSDGQVDLLRDFARPFPVAVIVRVLGLTDLDTDRLAQLSRTIAAVLEPN
HHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
AAVSAREAGDAALAELAGLLWDAVRADRGPHPDGFLRRLVDANKGLLSPEQLIATVLLLF
CCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LSGNDTITGLIANGVLALASVPDQADRLRAHPELLPMAVEEVLRFDAPACVAVRTTYEPM
HCCCCCEEHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCE
TIDGVTVERGAALLLAISSANRDPAAFAEPDVFRVDRRPIRHFAFGSGDHTCVGIGLARM
EECCEEECCCCEEEEEEECCCCCCCCCCCCCCEECCCCHHHHHCCCCCCCEEEEHHHHHH
EATIALEALLHRFPRLTHDPSTLRWSDALYLRSPENLVLLCTVPPAPERACGVPEVGLGR
HHHHHHHHHHHHCCCCCCCCCCEEECCEEEEECCCCEEEEEECCCCCHHHCCCCCCCCCC
DLG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]