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The map label for this gene is iap [H]

Identifier: 158317946

GI number: 158317946

Start: 7539174

End: 7540427

Strand: Direct

Name: iap [H]

Synonym: Franean1_6205

Alternate gene names: 158317946

Gene position: 7539174-7540427 (Clockwise)

Preceding gene: 158317942

Following gene: 158317948

Centisome position: 83.94

GC content: 76.24

Gene sequence:

>1254_bases
ATGCGCCCGGTCCTCATCACCCTGCTCGGCGTTCTCGCCGCCGGGCCATCGCTGACCGGCGCGGGCGGTGGCATCGGGGC
GGGCATGGCCCGCGCGGAGCCGAACGCGCCCACCCGCGGCGGCGACACCCGCAGCGACACCCCCGACGACACCCACGGCG
GCTCCGGCGGAGGGCCACAGGCCGGCCACGCCGAGGACCTCGGAAGCATCGCCGCCCAGATCACCTCGACCCGGGCCCAC
CTCGACGACCTCAGCCACAAGATGTCCGTAGCCGCCGAGCAGTACAACGCCGAACGCATCCGTCTCGCCGAGGCGGAGCG
CGCCGCGGCCACGGCCGCCCAGCAGCTGCGAACGGCGGACGTCGCCGTCCGGCGCGCTTCCGACCGGCACCGCGGCCTGG
CGACGTCGGCCTACCGCTCCGGCGGGCTGGAACAGCTCTCCATCCTGCTCACCGGCGATCCCCGCGCCGCGCTCGACCGC
GCCGGCGCCGTCGACGCGCTGTCCCGGCGGCAGCGGGCCGCCGAATCCGACCTGCGGCTGGCCCGCCACGACCAGACCGA
GGCGAAGCAGGCCGCCGACGAGACCCGCGCCGGCCGGCAACGGCTCGTCGACTCACTGGCCGAGCGCCGACGCGGGCTGG
AGAAGTCAGCCGGCGAGCAGGGCAGGCTGCTGGACGGCCTGATCGCCCGGCAGGCGGAGCTGGAGCGCCAGGCCCGGGAA
CGCGAGGCCGCCGCGCTGCGGGCCCGTAAGGCCGCCGAGGCCGCGGCCGCCGCCGAGACGGCCCGCCAGGCCGCCCTGGA
ACGCGACCGGCTCACCCGGGAGGCCGGTCTCGTCACGACGGCCGGCAACGCCTTCGCCGCGGCACCCGCCCGGCCGGCCG
CGCCACCCCCGACCGGCGGCAGCGGCGGCGCGGCCCGCGCCGTCCAGGAGGCGCGCGCCCAGCTCGGCAAGCCGTACGTC
TGGGGTGCCGAGGGCCCGGACAGCTTCGACTGCTCCGGACTCACCCAGTGGGTCTGGGGAAAGGCCGGCGTCGGCATCCC
GCACTACACAGGCGACCAGTGGACGGCCGGCCGGCGGGTCACCCGCGACAAGCTGATCCCCGGCGACCTGGTCTTCTTCG
GCGCTGACCTCTACCACGTCGGCATCTACATCGGGAACGGCCAGATGATCCACGCGCCGCGTACCGGCGAGGTCGTACGG
ATCGAGAACGTGTGGTGGTCGTCGTTCCAGGGCGGTGTCCGCCCGGGCGCCTGA

Upstream 100 bases:

>100_bases
CGGGGACCCGCCAGGTAACGCCAATGTAAGTACGCCAGCACTCGAAACAGACAAAGGTTCCCACCGGTCGGCAACGCGCC
GGACCATTGACGGACGGGGC

Downstream 100 bases:

>100_bases
CGCGCCAGGACGCGGTGCCCGACGACGCTCCGGCCCCACCCCCGGCCCCCGGCTTGTGCGTGACCCGTGTGGCTCTCCCC
CAATCGATGGAGCGAGCTGT

Product: NLP/P60 protein

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MRPVLITLLGVLAAGPSLTGAGGGIGAGMARAEPNAPTRGGDTRSDTPDDTHGGSGGGPQAGHAEDLGSIAAQITSTRAH
LDDLSHKMSVAAEQYNAERIRLAEAERAAATAAQQLRTADVAVRRASDRHRGLATSAYRSGGLEQLSILLTGDPRAALDR
AGAVDALSRRQRAAESDLRLARHDQTEAKQAADETRAGRQRLVDSLAERRRGLEKSAGEQGRLLDGLIARQAELERQARE
REAAALRARKAAEAAAAAETARQAALERDRLTREAGLVTTAGNAFAAAPARPAAPPPTGGSGGAARAVQEARAQLGKPYV
WGAEGPDSFDCSGLTQWVWGKAGVGIPHYTGDQWTAGRRVTRDKLIPGDLVFFGADLYHVGIYIGNGQMIHAPRTGEVVR
IENVWWSSFQGGVRPGA

Sequences:

>Translated_417_residues
MRPVLITLLGVLAAGPSLTGAGGGIGAGMARAEPNAPTRGGDTRSDTPDDTHGGSGGGPQAGHAEDLGSIAAQITSTRAH
LDDLSHKMSVAAEQYNAERIRLAEAERAAATAAQQLRTADVAVRRASDRHRGLATSAYRSGGLEQLSILLTGDPRAALDR
AGAVDALSRRQRAAESDLRLARHDQTEAKQAADETRAGRQRLVDSLAERRRGLEKSAGEQGRLLDGLIARQAELERQARE
REAAALRARKAAEAAAAAETARQAALERDRLTREAGLVTTAGNAFAAAPARPAAPPPTGGSGGAARAVQEARAQLGKPYV
WGAEGPDSFDCSGLTQWVWGKAGVGIPHYTGDQWTAGRRVTRDKLIPGDLVFFGADLYHVGIYIGNGQMIHAPRTGEVVR
IENVWWSSFQGGVRPGA
>Mature_417_residues
MRPVLITLLGVLAAGPSLTGAGGGIGAGMARAEPNAPTRGGDTRSDTPDDTHGGSGGGPQAGHAEDLGSIAAQITSTRAH
LDDLSHKMSVAAEQYNAERIRLAEAERAAATAAQQLRTADVAVRRASDRHRGLATSAYRSGGLEQLSILLTGDPRAALDR
AGAVDALSRRQRAAESDLRLARHDQTEAKQAADETRAGRQRLVDSLAERRRGLEKSAGEQGRLLDGLIARQAELERQARE
REAAALRARKAAEAAAAAETARQAALERDRLTREAGLVTTAGNAFAAAPARPAAPPPTGGSGGAARAVQEARAQLGKPYV
WGAEGPDSFDCSGLTQWVWGKAGVGIPHYTGDQWTAGRRVTRDKLIPGDLVFFGADLYHVGIYIGNGQMIHAPRTGEVVR
IENVWWSSFQGGVRPGA

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786421, Length=122, Percent_Identity=40.9836065573771, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787944, Length=122, Percent_Identity=36.0655737704918, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788001, Length=124, Percent_Identity=34.6774193548387, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 43759; Mature: 43759

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPVLITLLGVLAAGPSLTGAGGGIGAGMARAEPNAPTRGGDTRSDTPDDTHGGSGGGPQ
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGHAEDLGSIAAQITSTRAHLDDLSHKMSVAAEQYNAERIRLAEAERAAATAAQQLRTAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VAVRRASDRHRGLATSAYRSGGLEQLSILLTGDPRAALDRAGAVDALSRRQRAAESDLRL
HHHHHHHHHHCCCHHHHHHCCCCEEEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHH
ARHDQTEAKQAADETRAGRQRLVDSLAERRRGLEKSAGEQGRLLDGLIARQAELERQARE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHH
REAAALRARKAAEAAAAAETARQAALERDRLTREAGLVTTAGNAFAAAPARPAAPPPTGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEECCCCCCCCCCCCCC
SGGAARAVQEARAQLGKPYVWGAEGPDSFDCSGLTQWVWGKAGVGIPHYTGDQWTAGRRV
CCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCC
TRDKLIPGDLVFFGADLYHVGIYIGNGQMIHAPRTGEVVRIENVWWSSFQGGVRPGA
HHHCCCCCCEEEECCCEEEEEEEECCCEEEECCCCCCEEEEECCHHHHCCCCCCCCC
>Mature Secondary Structure
MRPVLITLLGVLAAGPSLTGAGGGIGAGMARAEPNAPTRGGDTRSDTPDDTHGGSGGGPQ
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGHAEDLGSIAAQITSTRAHLDDLSHKMSVAAEQYNAERIRLAEAERAAATAAQQLRTAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VAVRRASDRHRGLATSAYRSGGLEQLSILLTGDPRAALDRAGAVDALSRRQRAAESDLRL
HHHHHHHHHHCCCHHHHHHCCCCEEEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHH
ARHDQTEAKQAADETRAGRQRLVDSLAERRRGLEKSAGEQGRLLDGLIARQAELERQARE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHH
REAAALRARKAAEAAAAAETARQAALERDRLTREAGLVTTAGNAFAAAPARPAAPPPTGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEECCCCCCCCCCCCCC
SGGAARAVQEARAQLGKPYVWGAEGPDSFDCSGLTQWVWGKAGVGIPHYTGDQWTAGRRV
CCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCC
TRDKLIPGDLVFFGADLYHVGIYIGNGQMIHAPRTGEVVRIENVWWSSFQGGVRPGA
HHHCCCCCCEEEECCCEEEEEEEECCCEEEECCCCCCEEEEECCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1514809; 11679669; 1459966 [H]