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The map label for this gene is regX3 [H]

Identifier: 158317887

GI number: 158317887

Start: 7476992

End: 7477678

Strand: Reverse

Name: regX3 [H]

Synonym: Franean1_6145

Alternate gene names: 158317887

Gene position: 7477678-7476992 (Counterclockwise)

Preceding gene: 158317888

Following gene: 158317886

Centisome position: 83.25

GC content: 69.43

Gene sequence:

>687_bases
GTGACGGTGACCAGGCTGCTCGTGGTCGAGGACGAGGAGTCCTTCTCCGATGCGTTGTCGTTCATGTTGGAACGCGAGGG
GTTCGAGGTCGCCGTCGTCGGTGACGGGCCCAGCGCGCTGGCCGAGTTCGACCGGCACGGTGCCGACCTGATCCTGCTCG
ACCTCATGCTCCCCGGCCTGTCCGGGACGGAGGTCTGTCGCACGCTGCGTGCCCGCTCGACCGTGCCTGTGATCATGCTC
ACCGCCCGGGACAGCGAGATCGACAAGGTGGTCGGCCTCGAGCTGGGCGCCGACGACTACGTGACGAAGCCGTTCTCGGC
CCGCGAGCTCGTCGCCCGGATCCGCGCCGTCCTGCGCCGCCGGGTGGAGACCGAGGAGGTGTCCGACGCCACCCTGGAGG
TCGGCCGGGTGCGGATGGACGTCGAGCGGCATGTCGTCACCGTCGACGGCAGCCAGGTCGCGCTGCCGCTCAAGGAGTTC
GAGCTGCTGGAGATGTTCCTGCGCAACGCGGGCCGGGTGCTCACCCGCGGCCAGCTGATCGACCGGGTCTGGGGGTCGGA
CTACGTCGGCGACACCAAGACGCTCGACGTCCATGTGAAGCGCCTGCGCACCAAGATCGAGGCCGAGCCGGGGGCGCCGC
GGCACCTGGTGACGGTGCGTGGTCTGGGTTACAAGTTCGAGCCCTGA

Upstream 100 bases:

>100_bases
GGTGGCCCCTGTTCCCGGCACCGGCCGTAAAACGGTGTGACACCGCGCGGTGAAACATTTCGTCCCCGGAGATCCCGGCG
GACGCGGGAGTACAGGGAGC

Downstream 100 bases:

>100_bases
CCGGCTCCCGCCCCCCACTGGCCGGCTGACGTGGTCGGAAGCGGCACTAGGTTGGATGGGCGCCCGGGACGGACGGATTC
CGGGGCAGGCCACGCGCGGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTVTRLLVVEDEESFSDALSFMLEREGFEVAVVGDGPSALAEFDRHGADLILLDLMLPGLSGTEVCRTLRARSTVPVIML
TARDSEIDKVVGLELGADDYVTKPFSARELVARIRAVLRRRVETEEVSDATLEVGRVRMDVERHVVTVDGSQVALPLKEF
ELLEMFLRNAGRVLTRGQLIDRVWGSDYVGDTKTLDVHVKRLRTKIEAEPGAPRHLVTVRGLGYKFEP

Sequences:

>Translated_228_residues
MTVTRLLVVEDEESFSDALSFMLEREGFEVAVVGDGPSALAEFDRHGADLILLDLMLPGLSGTEVCRTLRARSTVPVIML
TARDSEIDKVVGLELGADDYVTKPFSARELVARIRAVLRRRVETEEVSDATLEVGRVRMDVERHVVTVDGSQVALPLKEF
ELLEMFLRNAGRVLTRGQLIDRVWGSDYVGDTKTLDVHVKRLRTKIEAEPGAPRHLVTVRGLGYKFEP
>Mature_227_residues
TVTRLLVVEDEESFSDALSFMLEREGFEVAVVGDGPSALAEFDRHGADLILLDLMLPGLSGTEVCRTLRARSTVPVIMLT
ARDSEIDKVVGLELGADDYVTKPFSARELVARIRAVLRRRVETEEVSDATLEVGRVRMDVERHVVTVDGSQVALPLKEFE
LLEMFLRNAGRVLTRGQLIDRVWGSDYVGDTKTLDVHVKRLRTKIEAEPGAPRHLVTVRGLGYKFEP

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=43.6123348017621, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=38.7387387387387, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=41.0714285714286, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=39.5454545454545, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=36.6812227074236, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=34.051724137931, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=40.1785714285714, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=35.8407079646018, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=40.0881057268723, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=37.7777777777778, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=35.7466063348416, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=36.1990950226244, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=32.8888888888889, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=31.4893617021277, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1788550, Length=127, Percent_Identity=31.496062992126, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25417; Mature: 25285

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTRLLVVEDEESFSDALSFMLEREGFEVAVVGDGPSALAEFDRHGADLILLDLMLPGL
CCEEEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCEEEEEHHCCCC
SGTEVCRTLRARSTVPVIMLTARDSEIDKVVGLELGADDYVTKPFSARELVARIRAVLRR
CHHHHHHHHHHCCCCCEEEEEECCCCHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RVETEEVSDATLEVGRVRMDVERHVVTVDGSQVALPLKEFELLEMFLRNAGRVLTRGQLI
HCCHHHHHHHHHHHHHHEEEEEEEEEEECCCEEEECHHHHHHHHHHHHCCCCCHHHHHHH
DRVWGSDYVGDTKTLDVHVKRLRTKIEAEPGAPRHLVTVRGLGYKFEP
HHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEECCC
>Mature Secondary Structure 
TVTRLLVVEDEESFSDALSFMLEREGFEVAVVGDGPSALAEFDRHGADLILLDLMLPGL
CEEEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCEEEEEHHCCCC
SGTEVCRTLRARSTVPVIMLTARDSEIDKVVGLELGADDYVTKPFSARELVARIRAVLRR
CHHHHHHHHHHCCCCCEEEEEECCCCHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RVETEEVSDATLEVGRVRMDVERHVVTVDGSQVALPLKEFELLEMFLRNAGRVLTRGQLI
HCCHHHHHHHHHHHHHHEEEEEEEEEEECCCEEEECHHHHHHHHHHHHCCCCCHHHHHHH
DRVWGSDYVGDTKTLDVHVKRLRTKIEAEPGAPRHLVTVRGLGYKFEP
HHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA