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The map label for this gene is cysH [H]

Identifier: 158317845

GI number: 158317845

Start: 7430729

End: 7431400

Strand: Reverse

Name: cysH [H]

Synonym: Franean1_6103

Alternate gene names: 158317845

Gene position: 7431400-7430729 (Counterclockwise)

Preceding gene: 158317846

Following gene: 158317844

Centisome position: 82.74

GC content: 72.02

Gene sequence:

>672_bases
ATGGATGCCGCGCTGAAGGCCCGGGCACTGCGGGCCGGCGACGAGCTTGAGGGCGCCCCGGCGGAGGAGATCCTCCAGTG
GGCCGCCGACGAGTTCGGCACCGGTCTCGTCGTCGCGGCGTCGATGGCCGAGGCGGTCCTCGTCGACATGCTCGCGCGCA
TCCGCTCGGACGTCCCGGTGGTCTTCATCGACACCGGCTACCACTTCGCGGAGACCATCGGCACCCGGGACGCCGTCGCG
CACACCTACTCGTTGCCGATCATCAGCGCCCGCCCGCAGCTCACCGTCGTCGGTCAGGACGCCGTGCACGGGCCGCGGCT
CTACGAGAGCGACCCGGACCTGTGCTGCCGGATGCGCAAGATCGTCCCGCTGGACCGCGCGCTCGCCCCCTACCGGGCCT
GGGCGGCCGGTTCGCGGCGGGTGGAGTCCGCCGGGCGCAAGAGCCTGCCGGTCGTCGGCTGGGATCAGCGCCGCGGCAAG
GTCAAGATCCACCCGCTGGCCACCTGGACGGATGAGGACGTCGAGCGGTATGTCCAGGAGCACAACGTGATCGTGAACCC
GCTGCTCTCCGACGGCTACGAGTCGGTGGGCTGCTGGCCGTGCACCCAGCGCGGCGCCGGCCGGGACGGCCGCTGGGCCG
GTACGACCAAGACCGAGTGCGGCATCCACTAG

Upstream 100 bases:

>100_bases
GGCGCGCCTTCCGGCTCAGTCTCACTGCGCTGGCCACAGCCAGAACAGGTTCGGCGAACGGCACCGTCGTGGCGCCGTCG
GACGTGGAGGAGAAGAACTG

Downstream 100 bases:

>100_bases
TTCGCTTGGCTCGCAACCGGGAGCCGGGTGGTGCACAGTTCGGGGCGGGTGGCCAGGACCACGCTGTACCGTGCACGCCG
TGGCAGTCGTGACACCTGGG

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MDAALKARALRAGDELEGAPAEEILQWAADEFGTGLVVAASMAEAVLVDMLARIRSDVPVVFIDTGYHFAETIGTRDAVA
HTYSLPIISARPQLTVVGQDAVHGPRLYESDPDLCCRMRKIVPLDRALAPYRAWAAGSRRVESAGRKSLPVVGWDQRRGK
VKIHPLATWTDEDVERYVQEHNVIVNPLLSDGYESVGCWPCTQRGAGRDGRWAGTTKTECGIH

Sequences:

>Translated_223_residues
MDAALKARALRAGDELEGAPAEEILQWAADEFGTGLVVAASMAEAVLVDMLARIRSDVPVVFIDTGYHFAETIGTRDAVA
HTYSLPIISARPQLTVVGQDAVHGPRLYESDPDLCCRMRKIVPLDRALAPYRAWAAGSRRVESAGRKSLPVVGWDQRRGK
VKIHPLATWTDEDVERYVQEHNVIVNPLLSDGYESVGCWPCTQRGAGRDGRWAGTTKTECGIH
>Mature_223_residues
MDAALKARALRAGDELEGAPAEEILQWAADEFGTGLVVAASMAEAVLVDMLARIRSDVPVVFIDTGYHFAETIGTRDAVA
HTYSLPIISARPQLTVVGQDAVHGPRLYESDPDLCCRMRKIVPLDRALAPYRAWAAGSRRVESAGRKSLPVVGWDQRRGK
VKIHPLATWTDEDVERYVQEHNVIVNPLLSDGYESVGCWPCTQRGAGRDGRWAGTTKTECGIH

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=220, Percent_Identity=32.7272727272727, Blast_Score=101, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6325425, Length=218, Percent_Identity=32.1100917431193, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 24419; Mature: 24419

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAALKARALRAGDELEGAPAEEILQWAADEFGTGLVVAASMAEAVLVDMLARIRSDVPV
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCE
VFIDTGYHFAETIGTRDAVAHTYSLPIISARPQLTVVGQDAVHGPRLYESDPDLCCRMRK
EEEECCCHHHHHHCCHHHHHHHCCCCEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHH
IVPLDRALAPYRAWAAGSRRVESAGRKSLPVVGWDQRRGKVKIHPLATWTDEDVERYVQE
HCCHHHHHHHHHHHHCCCHHHHHCCCCCCCEECCCCCCCEEEEEEECCCCHHHHHHHHHH
HNVIVNPLLSDGYESVGCWPCTQRGAGRDGRWAGTTKTECGIH
CCEEEECHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDAALKARALRAGDELEGAPAEEILQWAADEFGTGLVVAASMAEAVLVDMLARIRSDVPV
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCE
VFIDTGYHFAETIGTRDAVAHTYSLPIISARPQLTVVGQDAVHGPRLYESDPDLCCRMRK
EEEECCCHHHHHHCCHHHHHHHCCCCEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHH
IVPLDRALAPYRAWAAGSRRVESAGRKSLPVVGWDQRRGKVKIHPLATWTDEDVERYVQE
HCCHHHHHHHHHHHHCCCHHHHHCCCCCCCEECCCCCCCEEEEEEECCCCHHHHHHHHHH
HNVIVNPLLSDGYESVGCWPCTQRGAGRDGRWAGTTKTECGIH
CCEEEECHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]