Click here to switch to the map view.

The map label for this gene is fixC [C]

Identifier: 158317837

GI number: 158317837

Start: 7419066

End: 7420388

Strand: Reverse

Name: fixC [C]

Synonym: Franean1_6095

Alternate gene names: 158317837

Gene position: 7420388-7419066 (Counterclockwise)

Preceding gene: 158317839

Following gene: 158317836

Centisome position: 82.61

GC content: 71.43

Gene sequence:

>1323_bases
GTGACCAAGCGGATGACGGAACGGGACGGCACCCGGGCGGATGACCGCCCCGATGACCGCCCTGACGCCGACGTCATCGT
GGTTGGTGCCGGGCCGGGCGGCTCGGCCGCCGCGTACCACCTCGCCCGCACCGGGCTCGACGTCCTGCTGCTGGAGAAGA
GCACCTTCCCTCGGGAGAAGGTCTGCGGTGACGGGCTGACCCCGCGGGCCGTGCGCAGCCTCGTCGAGATGGGCATCGAC
ACATCGGTCGAGGCCGGCTGGCTGCGTAACAGGGGGCTGCGCATCATCGGCGGCGGTGTGCGCCTCGAGCTGCCGTGGCC
GGAGCTCGCGAGCTGGCCCGACTACGGCCTGGTTCGCCCGCGCGCGGACTTCGACGAGATGCTCGCCCGGCACGCGGTCA
AGGCCGGTGCCCGACTGGTCGAGGGCGCCTCCGTCACCGGGCCGGTGCGTGACGACCGGACGGGACGGGTGGTCGGCGTG
ACCGCGCGGGCCGGGGTCGACCGGGCTCCGGCCGAGTTCCGTGCCCCGGTTGTGGTCGCCGCCGACGGCAACAGCGCCCG
GATCGCGCAGGCGCTGGGGATCCGGCGCCGGGAGGACCGCCCGCTGGGCGTGGCCGTGCGGCGCTACTACCGCAGCCCGC
GCACGAACGACGACTTCCTCGAGTCCCACCTCGAGCTGTGGGAGGGCCCGCCGCGCCAGAGCCGGCTGCTGCCGGGCTAC
GGGTGGATCTTCGGTATGGGTGACGGCACCAGCAACGTCGGCCTGGGCATGCTCAACACCACCAGCGCTTTCCAGAACAC
CGACTACCGGGATCTGCTCCGCCGGTGGCTGAACGGGCTGCCGCCCGAGTGGGGCTACACCGAGGAGAACGCCACCGGCC
CGGTCCGCGGCAGCGCGCTGCCGATGGCCTTCAACCGCGCCCCGCACTACCAGGACGGAGTGCTCCTCGTCGGCGACGCC
GGCGGGATGGTGAACCCGTTCAACGGCGAGGGCATCGCATATGCGATGGAATCGGGCCGGATCGCCGCCGAGACGATCGT
CCTTGCGCTCGCCCGGCACTCCGGGCCGGCCCGGGAGCGGGCGCTCGGGCGATATCCGGAGATCCTGGCTCAGACATACG
GGGGGTATTACACCCTGGGCCGTTTGTTTGTACAGCTCATCGGGAATCCGACTGTGATGGCGCTGGGGACCAGGTACGGG
CTGCCTCGGCCCATGCTGATGCGTTTCGTCCTGAAAGTCATGGCGAATCTGACCGACCCGCGAGGAGGTGACGCCACGGA
TCGACTGATCAACGCGCTGACCCGGTTGGCGCCCGCCGCCTGA

Upstream 100 bases:

>100_bases
CACTCGGCGTGGCGCTCGTGAAGAATTTCACGAGCGCGCAAGCGGGAGACGTGGGACACGGCCCTGATCGGCCGACTGGC
GCGGGAATCCGGAGCAGCGC

Downstream 100 bases:

>100_bases
GCGCGGCCACGTTCGGAAGCAGCCGGTCGGGACGCCGGCAGCCGCCGGTATGGACTCCGGCGCACGTGCTCGCACGCGAC
ACCTCCCGATAGTCGCGCGT

Product: geranylgeranyl reductase

Products: NA

Alternate protein names: DGGGPL reductase; 2,3-di-O-geranylgeranylglyceryl phosphate reductase; Geranylgeranyl reductase; GGR [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTKRMTERDGTRADDRPDDRPDADVIVVGAGPGGSAAAYHLARTGLDVLLLEKSTFPREKVCGDGLTPRAVRSLVEMGID
TSVEAGWLRNRGLRIIGGGVRLELPWPELASWPDYGLVRPRADFDEMLARHAVKAGARLVEGASVTGPVRDDRTGRVVGV
TARAGVDRAPAEFRAPVVVAADGNSARIAQALGIRRREDRPLGVAVRRYYRSPRTNDDFLESHLELWEGPPRQSRLLPGY
GWIFGMGDGTSNVGLGMLNTTSAFQNTDYRDLLRRWLNGLPPEWGYTEENATGPVRGSALPMAFNRAPHYQDGVLLVGDA
GGMVNPFNGEGIAYAMESGRIAAETIVLALARHSGPARERALGRYPEILAQTYGGYYTLGRLFVQLIGNPTVMALGTRYG
LPRPMLMRFVLKVMANLTDPRGGDATDRLINALTRLAPAA

Sequences:

>Translated_440_residues
MTKRMTERDGTRADDRPDDRPDADVIVVGAGPGGSAAAYHLARTGLDVLLLEKSTFPREKVCGDGLTPRAVRSLVEMGID
TSVEAGWLRNRGLRIIGGGVRLELPWPELASWPDYGLVRPRADFDEMLARHAVKAGARLVEGASVTGPVRDDRTGRVVGV
TARAGVDRAPAEFRAPVVVAADGNSARIAQALGIRRREDRPLGVAVRRYYRSPRTNDDFLESHLELWEGPPRQSRLLPGY
GWIFGMGDGTSNVGLGMLNTTSAFQNTDYRDLLRRWLNGLPPEWGYTEENATGPVRGSALPMAFNRAPHYQDGVLLVGDA
GGMVNPFNGEGIAYAMESGRIAAETIVLALARHSGPARERALGRYPEILAQTYGGYYTLGRLFVQLIGNPTVMALGTRYG
LPRPMLMRFVLKVMANLTDPRGGDATDRLINALTRLAPAA
>Mature_439_residues
TKRMTERDGTRADDRPDDRPDADVIVVGAGPGGSAAAYHLARTGLDVLLLEKSTFPREKVCGDGLTPRAVRSLVEMGIDT
SVEAGWLRNRGLRIIGGGVRLELPWPELASWPDYGLVRPRADFDEMLARHAVKAGARLVEGASVTGPVRDDRTGRVVGVT
ARAGVDRAPAEFRAPVVVAADGNSARIAQALGIRRREDRPLGVAVRRYYRSPRTNDDFLESHLELWEGPPRQSRLLPGYG
WIFGMGDGTSNVGLGMLNTTSAFQNTDYRDLLRRWLNGLPPEWGYTEENATGPVRGSALPMAFNRAPHYQDGVLLVGDAG
GMVNPFNGEGIAYAMESGRIAAETIVLALARHSGPARERALGRYPEILAQTYGGYYTLGRLFVQLIGNPTVMALGTRYGL
PRPMLMRFVLKVMANLTDPRGGDATDRLINALTRLAPAA

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004792
- InterPro:   IPR011777
- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3; PF03486 HI0933_like [H]

EC number: NA

Molecular weight: Translated: 47810; Mature: 47679

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRMTERDGTRADDRPDDRPDADVIVVGAGPGGSAAAYHLARTGLDVLLLEKSTFPREK
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCHHH
VCGDGLTPRAVRSLVEMGIDTSVEAGWLRNRGLRIIGGGVRLELPWPELASWPDYGLVRP
HCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCEEEEECCEEEEECCHHHCCCCCCCCCCC
RADFDEMLARHAVKAGARLVEGASVTGPVRDDRTGRVVGVTARAGVDRAPAEFRAPVVVA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHCCCEEEE
ADGNSARIAQALGIRRREDRPLGVAVRRYYRSPRTNDDFLESHLELWEGPPRQSRLLPGY
ECCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GWIFGMGDGTSNVGLGMLNTTSAFQNTDYRDLLRRWLNGLPPEWGYTEENATGPVRGSAL
CEEEECCCCCCCCCCEEEECCHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PMAFNRAPHYQDGVLLVGDAGGMVNPFNGEGIAYAMESGRIAAETIVLALARHSGPARER
CEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHH
ALGRYPEILAQTYGGYYTLGRLFVQLIGNPTVMALGTRYGLPRPMLMRFVLKVMANLTDP
HHCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
RGGDATDRLINALTRLAPAA
CCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKRMTERDGTRADDRPDDRPDADVIVVGAGPGGSAAAYHLARTGLDVLLLEKSTFPREK
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCHHH
VCGDGLTPRAVRSLVEMGIDTSVEAGWLRNRGLRIIGGGVRLELPWPELASWPDYGLVRP
HCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCEEEEECCEEEEECCHHHCCCCCCCCCCC
RADFDEMLARHAVKAGARLVEGASVTGPVRDDRTGRVVGVTARAGVDRAPAEFRAPVVVA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHCCCEEEE
ADGNSARIAQALGIRRREDRPLGVAVRRYYRSPRTNDDFLESHLELWEGPPRQSRLLPGY
ECCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GWIFGMGDGTSNVGLGMLNTTSAFQNTDYRDLLRRWLNGLPPEWGYTEENATGPVRGSAL
CEEEECCCCCCCCCCEEEECCHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PMAFNRAPHYQDGVLLVGDAGGMVNPFNGEGIAYAMESGRIAAETIVLALARHSGPARER
CEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHH
ALGRYPEILAQTYGGYYTLGRLFVQLIGNPTVMALGTRYGLPRPMLMRFVLKVMANLTDP
HHCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
RGGDATDRLINALTRLAPAA
CCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a quinone or similar compound as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA