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The map label for this gene is nuoH [H]

Identifier: 158317829

GI number: 158317829

Start: 7409281

End: 7410669

Strand: Reverse

Name: nuoH [H]

Synonym: Franean1_6087

Alternate gene names: 158317829

Gene position: 7410669-7409281 (Counterclockwise)

Preceding gene: 158317830

Following gene: 158317828

Centisome position: 82.51

GC content: 68.39

Gene sequence:

>1389_bases
ATGACCGGGACCTCGACGCTCCTGCTCGCCGCGAACGTCGGCGACCCGGACATGTCCGTCCTCACCGACGACCCGTTCTG
GCTCATCCTGATCAAGGCTGTCGCGGTCTTCGCGTTCCTGCTGGTGATGACGCTGTTCTCGATCGTCTTCGAGCGCAAGG
TCGTCGCGAAGATGCAGCAGCGGGTCGGGCCGAACCGGCACGGCCCGCGCGGCTGGCTGCAGAGCCTCGCCGACGGCGTG
AAGCTCATGCTCAAGGAAGACATCATCCCGACGCTGGCCGACAAGCCGATCTTCATCCTGGCTCCGGTCATCTCGGCGGT
GCCGGCCATCCTGGCCTTCGCCTGCATCCCGTTCGGGCCGGAGGTGTCGATCTTCGGTGAACGCACGACGCTCCAGCTCG
CCGACCTGCCGGTCAGCGTGCTGTACCTGCTGGCGGCGGCGTCGCTGGGCGTGTACGGACTGATCCTCGCCGGCTGGTCC
AGCGGCTCGACCTACCCGCTGCTGGGCTCGCTGCGCTCGGCCGCGCAGATCATCTCCTACGAAGTCGCGATGGGCCTGGC
CTTCGTCGCGGTCTTCGTCTACGCGGGAACACTGTCGACCGCGGGCATCGTGCAGAGCCAGCACGACTGGTGGTACATCG
CGCTGCTGCCGTCGTTCATCCTCTACTGCATCGCGATGGTCGGTGAGACGAACCGGACGCCGTTCGACCTCCCCGAGGCC
GAGGGCGAGCTGGTCGGCGGGTTCCACACCGAGTACAGCTCGATCAAGTTCGCGTTCTTCTTCCTCGCCGAGTACATCAA
CATGGTCACCGTCTCGGCGATCGCGACCACACTGTTCCTCGGAGGCTGGCAGCCGCCGCCGATCCCGGGCCTGTCCGGGC
TGGACCACGGCTGGTACCCGCTGATCTGGTTCGTCATCAAGCTGCTGCTGTTCATCTTCGTGTTCATCTGGCTGCGGGGC
ACGCTGCCGCGGCTGCGCTACGACCAGTTCATGGCCTTCGGCTGGAAGGTCCTGATCCCGGTCGGCCTGGTGTGGGTGCT
CGCGGTCGCGACCTTCCGCGCCTACCAGGAGCACGTGAGTGACCGGACGCCATGGCTGATCGGCTTCGGGGTCGTGGTGG
GCGTCCTGCTCGTGGTTGCGATCATCGACCCGGGCGCGGCGAGGGCCCAGCGCGAGCAGGAGGAGGCCGAGCGGGAACGC
GCCGAATCGGCCCCGAGCCTGGACAGGATTCCCTGGCCGCCGCCGTCCGACGGCGCGACGAGGGCACTGGCCGGCCGCAC
TGCGGCTGGCAGCACTGCAGCCGGCAGCGGCGCGGCCGGCTCCGCCGGCGGCGACAAGGGAAACACCACCGTCATCCCCG
CGGGCTCCGGCCCGCGACAGGAGAGCTGA

Upstream 100 bases:

>100_bases
CGCTCGGCTCGCAGCTCGCGGCCGCCCAGGACACCGCCGTGACCGTGGCCCACACCGGCCTCGGTGCCGCGGGCCGGGTC
GACACCACCGGAGGCCGGGC

Downstream 100 bases:

>100_bases
ACCATGGGGATCCTCGACCCCTACAAGGGTTTCGGCGTCACCTTCTCGACGATGTTCAAGAAGCCGACGACCGAGCAGTA
CCCGGAGCAGAAGAAGGAGA

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MTGTSTLLLAANVGDPDMSVLTDDPFWLILIKAVAVFAFLLVMTLFSIVFERKVVAKMQQRVGPNRHGPRGWLQSLADGV
KLMLKEDIIPTLADKPIFILAPVISAVPAILAFACIPFGPEVSIFGERTTLQLADLPVSVLYLLAAASLGVYGLILAGWS
SGSTYPLLGSLRSAAQIISYEVAMGLAFVAVFVYAGTLSTAGIVQSQHDWWYIALLPSFILYCIAMVGETNRTPFDLPEA
EGELVGGFHTEYSSIKFAFFFLAEYINMVTVSAIATTLFLGGWQPPPIPGLSGLDHGWYPLIWFVIKLLLFIFVFIWLRG
TLPRLRYDQFMAFGWKVLIPVGLVWVLAVATFRAYQEHVSDRTPWLIGFGVVVGVLLVVAIIDPGAARAQREQEEAERER
AESAPSLDRIPWPPPSDGATRALAGRTAAGSTAAGSGAAGSAGGDKGNTTVIPAGSGPRQES

Sequences:

>Translated_462_residues
MTGTSTLLLAANVGDPDMSVLTDDPFWLILIKAVAVFAFLLVMTLFSIVFERKVVAKMQQRVGPNRHGPRGWLQSLADGV
KLMLKEDIIPTLADKPIFILAPVISAVPAILAFACIPFGPEVSIFGERTTLQLADLPVSVLYLLAAASLGVYGLILAGWS
SGSTYPLLGSLRSAAQIISYEVAMGLAFVAVFVYAGTLSTAGIVQSQHDWWYIALLPSFILYCIAMVGETNRTPFDLPEA
EGELVGGFHTEYSSIKFAFFFLAEYINMVTVSAIATTLFLGGWQPPPIPGLSGLDHGWYPLIWFVIKLLLFIFVFIWLRG
TLPRLRYDQFMAFGWKVLIPVGLVWVLAVATFRAYQEHVSDRTPWLIGFGVVVGVLLVVAIIDPGAARAQREQEEAERER
AESAPSLDRIPWPPPSDGATRALAGRTAAGSTAAGSGAAGSAGGDKGNTTVIPAGSGPRQES
>Mature_461_residues
TGTSTLLLAANVGDPDMSVLTDDPFWLILIKAVAVFAFLLVMTLFSIVFERKVVAKMQQRVGPNRHGPRGWLQSLADGVK
LMLKEDIIPTLADKPIFILAPVISAVPAILAFACIPFGPEVSIFGERTTLQLADLPVSVLYLLAAASLGVYGLILAGWSS
GSTYPLLGSLRSAAQIISYEVAMGLAFVAVFVYAGTLSTAGIVQSQHDWWYIALLPSFILYCIAMVGETNRTPFDLPEAE
GELVGGFHTEYSSIKFAFFFLAEYINMVTVSAIATTLFLGGWQPPPIPGLSGLDHGWYPLIWFVIKLLLFIFVFIWLRGT
LPRLRYDQFMAFGWKVLIPVGLVWVLAVATFRAYQEHVSDRTPWLIGFGVVVGVLLVVAIIDPGAARAQREQEEAERERA
ESAPSLDRIPWPPPSDGATRALAGRTAAGSTAAGSGAAGSAGGDKGNTTVIPAGSGPRQES

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=300, Percent_Identity=37.3333333333333, Blast_Score=194, Evalue=2e-49,
Organism=Escherichia coli, GI1788618, Length=332, Percent_Identity=42.4698795180723, Blast_Score=257, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 49748; Mature: 49616

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTSTLLLAANVGDPDMSVLTDDPFWLILIKAVAVFAFLLVMTLFSIVFERKVVAKMQQ
CCCCCEEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVGPNRHGPRGWLQSLADGVKLMLKEDIIPTLADKPIFILAPVISAVPAILAFACIPFGP
HCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
EVSIFGERTTLQLADLPVSVLYLLAAASLGVYGLILAGWSSGSTYPLLGSLRSAAQIISY
CEEEECCCEEEEEHHCHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHH
EVAMGLAFVAVFVYAGTLSTAGIVQSQHDWWYIALLPSFILYCIAMVGETNRTPFDLPEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EGELVGGFHTEYSSIKFAFFFLAEYINMVTVSAIATTLFLGGWQPPPIPGLSGLDHGWYP
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
LIWFVIKLLLFIFVFIWLRGTLPRLRYDQFMAFGWKVLIPVGLVWVLAVATFRAYQEHVS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DRTPWLIGFGVVVGVLLVVAIIDPGAARAQREQEEAERERAESAPSLDRIPWPPPSDGAT
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
RALAGRTAAGSTAAGSGAAGSAGGDKGNTTVIPAGSGPRQES
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TGTSTLLLAANVGDPDMSVLTDDPFWLILIKAVAVFAFLLVMTLFSIVFERKVVAKMQQ
CCCCEEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVGPNRHGPRGWLQSLADGVKLMLKEDIIPTLADKPIFILAPVISAVPAILAFACIPFGP
HCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
EVSIFGERTTLQLADLPVSVLYLLAAASLGVYGLILAGWSSGSTYPLLGSLRSAAQIISY
CEEEECCCEEEEEHHCHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHH
EVAMGLAFVAVFVYAGTLSTAGIVQSQHDWWYIALLPSFILYCIAMVGETNRTPFDLPEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EGELVGGFHTEYSSIKFAFFFLAEYINMVTVSAIATTLFLGGWQPPPIPGLSGLDHGWYP
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
LIWFVIKLLLFIFVFIWLRGTLPRLRYDQFMAFGWKVLIPVGLVWVLAVATFRAYQEHVS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DRTPWLIGFGVVVGVLLVVAIIDPGAARAQREQEEAERERAESAPSLDRIPWPPPSDGAT
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
RALAGRTAAGSTAAGSGAAGSAGGDKGNTTVIPAGSGPRQES
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA