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The map label for this gene is map [H]

Identifier: 158317769

GI number: 158317769

Start: 7348556

End: 7349395

Strand: Reverse

Name: map [H]

Synonym: Franean1_6027

Alternate gene names: 158317769

Gene position: 7349395-7348556 (Counterclockwise)

Preceding gene: 158317770

Following gene: 158317768

Centisome position: 81.82

GC content: 70.6

Gene sequence:

>840_bases
GTGGCACGACGAGAGCACGTCCAGATCAAGACGGCATCCGAGATCGCCAAGATGCGGGTGGCCGGGCTGCTCGTCGCGAA
GACCCTGGCGGCCTTGCGCGCGGCGGTGGCTCCGGGCGTCACCACGGAGGATCTCGATGCCCTCGCGGAGAAGACGATCC
GTGCCGACGGGGGCATCCCGTCCTTCAAGGGCTACGCGCACCCTCCGTACCCGGCCTCGATCTGTAGCTCGGTGAACAAC
GAGGTGGTCCACGCGATCCCCAGCCGGCGCCGGGTGCTGCGCGAGGGGGACATCATCTCCATCGACTGCGGCGCGATCGT
CGACGGCTGGCACGGCGACGCCGCGATCACCGTCCCGGTCGGCGAGGTGCCCTCCGAGGTCCTGGACATGCTCCGGGTCT
GCGACGAGGCCCTGTGGCGCGGCCTTGCCGCCGCGCAGCTCGGCGGCCGGCTGACGGACATCAGCAACGTGGTCGAACGG
CACATCGTCCCTCACGGCTACGGCATCGTCGACCACTACGGCGGTCACGGCATCGGGTCGGAGATGCACCAGCCGCCGCA
TGTGCTGAACTACGGCCGGGCCGGCCGGGGGATGAAGCTGGTCGAGGGCGTCGCGCTCGCGATCGAGCCGATGATCACTC
TTGGCTCGCCGGACACCGTCGTCCTCGAGGACGAGTGGACGGTCGCGACCAAGGACGGCTCGCTCGCCGCCCACACCGAG
CACTCCGTCGCTGTCACCCCACGTGGTCCGTGGGTGCTCACCGAGCCCGACGGCGGCGTGGCGAGGTTCGCGGAGCTGGG
TGTGGCCTGTGGGCAGCCCGCCGACGCACCCACAGGCTGA

Upstream 100 bases:

>100_bases
GGCGGCAGCGTCGGCGGGGTTCGGACCCCGGCCGGGCTCAGACGAGGCGACGGGCACCTGTACGTCGCGAACACTACTGA
GGGACGGGACCGGGTAGAGC

Downstream 100 bases:

>100_bases
GCGATCAGCCCCGCCCGTCGGTCCGATCGGGGTCGTGTGGGGCCCGTGTTGGCCCTTGACGGATGCGGCACGTACACTCA
TGAGTCGACGGTCTACAGCG

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MARREHVQIKTASEIAKMRVAGLLVAKTLAALRAAVAPGVTTEDLDALAEKTIRADGGIPSFKGYAHPPYPASICSSVNN
EVVHAIPSRRRVLREGDIISIDCGAIVDGWHGDAAITVPVGEVPSEVLDMLRVCDEALWRGLAAAQLGGRLTDISNVVER
HIVPHGYGIVDHYGGHGIGSEMHQPPHVLNYGRAGRGMKLVEGVALAIEPMITLGSPDTVVLEDEWTVATKDGSLAAHTE
HSVAVTPRGPWVLTEPDGGVARFAELGVACGQPADAPTG

Sequences:

>Translated_279_residues
MARREHVQIKTASEIAKMRVAGLLVAKTLAALRAAVAPGVTTEDLDALAEKTIRADGGIPSFKGYAHPPYPASICSSVNN
EVVHAIPSRRRVLREGDIISIDCGAIVDGWHGDAAITVPVGEVPSEVLDMLRVCDEALWRGLAAAQLGGRLTDISNVVER
HIVPHGYGIVDHYGGHGIGSEMHQPPHVLNYGRAGRGMKLVEGVALAIEPMITLGSPDTVVLEDEWTVATKDGSLAAHTE
HSVAVTPRGPWVLTEPDGGVARFAELGVACGQPADAPTG
>Mature_278_residues
ARREHVQIKTASEIAKMRVAGLLVAKTLAALRAAVAPGVTTEDLDALAEKTIRADGGIPSFKGYAHPPYPASICSSVNNE
VVHAIPSRRRVLREGDIISIDCGAIVDGWHGDAAITVPVGEVPSEVLDMLRVCDEALWRGLAAAQLGGRLTDISNVVERH
IVPHGYGIVDHYGGHGIGSEMHQPPHVLNYGRAGRGMKLVEGVALAIEPMITLGSPDTVVLEDEWTVATKDGSLAAHTEH
SVAVTPRGPWVLTEPDGGVARFAELGVACGQPADAPTG

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=253, Percent_Identity=35.5731225296443, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI164420681, Length=249, Percent_Identity=32.5301204819277, Blast_Score=140, Evalue=1e-33,
Organism=Escherichia coli, GI1786364, Length=249, Percent_Identity=36.5461847389558, Blast_Score=167, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71996291, Length=260, Percent_Identity=32.3076923076923, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323273, Length=253, Percent_Identity=31.6205533596838, Blast_Score=142, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24583427, Length=247, Percent_Identity=34.0080971659919, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21355531, Length=253, Percent_Identity=33.596837944664, Blast_Score=143, Evalue=1e-34,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29333; Mature: 29202

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARREHVQIKTASEIAKMRVAGLLVAKTLAALRAAVAPGVTTEDLDALAEKTIRADGGIP
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCC
SFKGYAHPPYPASICSSVNNEVVHAIPSRRRVLREGDIISIDCGAIVDGWHGDAAITVPV
CCCCCCCCCCCHHHHHHHCCHHHHHCHHHHHHHHCCCEEEEECCCEEECCCCCEEEEEEC
GEVPSEVLDMLRVCDEALWRGLAAAQLGGRLTDISNVVERHIVPHGYGIVDHYGGHGIGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EMHQPPHVLNYGRAGRGMKLVEGVALAIEPMITLGSPDTVVLEDEWTVATKDGSLAAHTE
CCCCCCCHHCCCCCCCCHHHHHHHHHHHCCEEEECCCCEEEEECCEEEEECCCCEEEECC
HSVAVTPRGPWVLTEPDGGVARFAELGVACGQPADAPTG
CEEEECCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ARREHVQIKTASEIAKMRVAGLLVAKTLAALRAAVAPGVTTEDLDALAEKTIRADGGIP
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCC
SFKGYAHPPYPASICSSVNNEVVHAIPSRRRVLREGDIISIDCGAIVDGWHGDAAITVPV
CCCCCCCCCCCHHHHHHHCCHHHHHCHHHHHHHHCCCEEEEECCCEEECCCCCEEEEEEC
GEVPSEVLDMLRVCDEALWRGLAAAQLGGRLTDISNVVERHIVPHGYGIVDHYGGHGIGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EMHQPPHVLNYGRAGRGMKLVEGVALAIEPMITLGSPDTVVLEDEWTVATKDGSLAAHTE
CCCCCCCHHCCCCCCCCHHHHHHHHHHHCCEEEECCCCEEEEECCEEEEECCCCEEEECC
HSVAVTPRGPWVLTEPDGGVARFAELGVACGQPADAPTG
CEEEECCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]