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The map label for this gene is mbtB [H]

Identifier: 158317684

GI number: 158317684

Start: 7240173

End: 7245209

Strand: Reverse

Name: mbtB [H]

Synonym: Franean1_5942

Alternate gene names: 158317684

Gene position: 7245209-7240173 (Counterclockwise)

Preceding gene: 158317685

Following gene: 158317683

Centisome position: 80.66

GC content: 76.06

Gene sequence:

>5037_bases
GTGAGAGCGCAAGGGAGTTACCGCAGCAGGTCGGTCCCGCTCGACCAGGCGCCGCAGGCCGCCGCCGCGGGTCTCGCGCG
CGGGCTGGCCGCGCCGTTCGTGCTCTACGAGCGCGACGGAGAGTGGTCCTGCGGCTCGGGGGTGCTCGCCGAGGTCGTGC
TGAGCGCCACCGAGGTGAGGCACCGGACGGGCAGCGGCGACTGGCGGTCCGAGCCGACCGGAGCCACCCCGCTGCGCCAG
GTCGCGAATGTCCTCGGCGGCCTCGAGGCGACCGGGTGGCGGGCCTACGGCTGGGCGGCGTTCGAGCTCAGCCTGCTCCT
GCAGGGCCAGCCGGTGCCGGCCGGCGACGATCCGCTGCTGCACGTGATCGTGCCACGGCGGGAGGTGCGGCTGATCGACG
GGGTCGCCGTCCTGCGCGCCGTCGACACCGCCGATCTGGCGGAGCTGGCCAAGCTGCTCGCCGCCGTGCCGAGCGGCCCG
CCGGCGGCCAGCGCCCCGCGCGCCGTCGTCGACCTCGAGCACGGGGTCGACGAGTACCGCCGGATCGTCGCGGCGGCCGT
CGCCGACATCCGCGCCGAACGGCTGCGCAAGGTGATCCTCTCCCGCGTCGTGCCCGTGGCGGGCGACGTCGACCTGGTGG
CCACCTACGAGGTCGGCCGGGCCGGGAACAACCCGGCGCGGTCGTTCATCGTGGACACGGGCCACCTGCGGGCCACCGGG
TTCAGCCCGGAGACCGTCGTCGAGGTGTCCGCGGACGGCCTGGTGTCGACCCAGCCGCTGGCCGGCACCCGGGCGCTGAC
CGGCGATCCCGCCGTCGACCGCGATCTGCGCGAGGTGCTGCTCTCCGATCCCAAGGAGATCTACGAGCACGCTGTCTCCG
TACAGGCCTGCCAGGACGAGCTGCTCCAGGTCTGCCGGCCCGGGTCGGTGGTCGTGGACCAGTTCATGAACGTGCTGCCC
CGCGGCAGCGTCCAGCACCTTGCCTCGCGGGTGGCCGGCCGGCTCGCCGCCGGCCGCGACGCCTGGGACGCACTGGGCGC
GGTCTTCCCCTCCATCACCGCCTCCGGCGTGCCCAAGCCGGTCGCGTGCGCGGTGATCGGCGACTACGAGGGGGAGCTCC
GCGGCCTGTACAGCGGCGCGGTGCTGATCGCTGACTCCGACGGCGGGCTCGACGCGGCGCTGGTGCTGCGCACGGTGTTC
CAGCAGGACGGCCGGACCTGGCTGCGCGCCGGGGCCGGCATCGTCGGCCACTCCGACCCCGACCGCGAGGCGGAGGAGAC
CCGGGAGAAGCTGCGCAGCGTCAGCCGTTTCCTGGTCGCGGCGCCCGCCGCGCCGGCCGCCCCGGCTGTTCCCGCCGCGC
GGGCGGGCACCCCCGGGTACCAGCTCGAGGATGTCCGCCGCATCGTGGCCGAGCTGATCGACGAGGATCCGTCGGCGATC
GGCAACGAGGCGAACCTGTTCGAGCTGGGCCTGGAGTCCATCGCCCTGATGAAGGCCGTCGGCCGCTGGCGCCGGGCCGG
GATGGCGGTCTCGTTCGCCGAGCTCGCGGAGAACCCGACCGTCGACGGCTGGTGCAAGCTCCTGTCGATGCGGGCGCCCA
CCGAGCCCGCCGGCGCGGACGACGGCGCGCAGGCCCGCGCGGAGGCCGGTGAGTTCCCGCTCGCGCTCATGCAGCATGCC
TACTGGGTCGGCCGGGACGGCGGGCAGCCGCTCGGCGAGGTCGCGGCGCACCTCTACACCGAGTTCGACGGCGCGGGAGT
CGACGTCGACCGGCTGCGCACGGCTATCGAGGCGCTCGTCGCGCGGCACGACATGCTGCGCGTGCGGATCACGGACAACG
GGAGCCAGGTCGTCGAGGCGACCTCGGGCTGGCGCGGTCTCACCGTGCACGACCTGCGCGAGCTCGGCCAGGCCGAGACC
CAGGCCCGGCTCGCCGCGGTGCGGGACCGGATGTCGCACCAGATGCTGGACATCGAGCACGGCGAGGTGTTCGCCACCGC
GCTGAGCCTGCTGCCGCAGGGCCGGACCAGGCTCCACCTGGACGTCGACATGGTCGCGGCCGACGCCGTCAGCTACCGGG
TGCTGCTCAACGACCTCGCGCGGTTCTACGACCGTCCCGGCGAGGAGCACCCGCCGCTGGGCTACACCTATCGCGAGTAC
CGCGCCGCGCGGGTCCCGGCCAGGCGCGCCGCCGCGCGCGCGGCCGCCGAGTGGTGGCAGGGCCGGCTGCCGGGCCTGCC
CGGCGCGCCCGGCCTGCCCCGCCTGGCCTCGCCCGACGACGCGGGCACCGCCTCGAGCGCCGGCGCCGCGAGCACGGCGG
GCGCTACCGGCTCCACCGGCGAGCCGCCGCGGGTGACGCGGCGTCACTTCGTCCTGGGGCCGTCGGCGCGCCAGGCGTTG
CAGCGCGCCGCCCACAGCCGGGGCGTCACCCCGGCGATGGCGGTGGCGACCGCGTTCGCCGAGGTGCTCGCCGGGTGGAG
CACCGAGTCCCGGTTCGTCCTCAACGTGCCGATGTTCGACCGCGACCAGGTGCACGCGGACGTCAACCAGGTGGTCGGGG
ACTTCACGAGCTCGGTGCTGCTCGAGGTCGACCTGGCCGAGCCGCAGCCGTTCGCGACCCGGGTGCGCCAGGTCCAGGCC
CGGCTGCACGCCGACGCGGCGCACGCGGACTACTCCGGTGTGGAGGTGCTGCGCGACCTGACCCGCCGCACCGGCGAGCA
GGTGCTGGCGCCCGTGGTGTTCACCAGCGCGCTCGGGCTCGGGGAGCTGTTCGGCCCCGGGGTCCGCCAGCACTTCGGCG
ACCCGGTGTGGATCATCTCGCAGGGCCCCCAGGTGCTCCTGGACGCGCAGGTCACCGAGCTGGACGGCGGCCTGCTCGTC
AACTGGGACGTCCGCGACGGCGAGTTCGCCCCGGGCGTGGTCGACGCGATGTTCGGCGCCTTCGAACGGCTGGTGCGCGG
CCTCGCCGACACCGCGGGCACCTGGGACACGGCGGTCGACGGCCTGGTGCCGGAACCGGCCCGTGCCATCCGCGCCGCGG
CCAACGACACCGCCGGGCCGGTGCCGACCCGGCTGCTGCACGAGGGGTTCTTCGAGAACGCCGTGCTGGCCCCCGACGCC
CCCGCGCTGCTGTGGGACACCGCCGGCGGCCCGGGTTCGCTGGCCTACGGCGAGCTGCGGCGCCGGGCGCTGGGGCTGGC
CGGCGCGCTGGCCGGCCACGGCGTGCGCCGCGGCGACCTGGTCGGAGTCAGCCTGCCCAAGGGGCCGTCCCAGGTGGTCG
CCGTCCTCGGCGTCCTGGCGGCGGGCGCGACGTACGTGCCGGTCGGCATCGAGCAGCCCGCCGCCCGGGTGGAGCGGATC
GCGGCCGCCGCCGGGTTCGGGGTGCTCATCACCGAGTCGCACCGCGACGGCGTGCCCGCCGGGGTCGTCCAGCTGGCGCC
GGACCAGCCCGCCGAGCCGGCGCCGGTACCGGATCTCGCCGCCCCCGGCGAGCTCGGGGGGCTGGACCGGCCGGCCTACG
TGCTCTTCACCTCCGGATCGACCGGTCAGCCCAAGGGCGTGGAGGTCGGGCACCGGGCGGCGATGAACACGATCGCCGAC
CTGATCGACCGGCTGGGCCTGGGCACCGACGACCGGACGCTCGCCGTGTCGGCGCTGGACTTCGACCTCTCGGTGTTCGA
CATCTTCGCCCCGCTGTCGGCCGGCGGCGCCGTGGCGCTCGTCGACGAGGACTCCCGCCGGGAGGCCAGCCGGTGGGCGG
AGCTGATCCGCGACCACCGGGTGACCGTCCTCAACTGCGTCCCCACGGTGCTGGACCTCGTCCTCGCCGCCGGGGTGGCG
CTCGGGGACAGCCTGCGGGCGGTCCTGCTCGGCGGCGACAAGGTGGGCGTGGACCTGCCGGGCCGGCTCGCCGCGGCGGT
GCCGGGCTGCCGGTTCCTGGGCCTGGGCGGCACGACTGAGACGGCCATCCACTCGACGATCTGCGAGGTGGAGGGGGCGT
CCCCGCTGCCGCCGCAGTGGCGCTTGGTCCCCTACGGGACGCCGCTGCGCAACGTCCGGCTGCGGGTGGTCGACCCGCTC
GGCCGAGACTGCCCCGACCACGTGGCCGGGGAGCTCTGGATCGGCGGTGACGGCGTCGCCCGCGGCTACCTGGGCGATCC
CGAGCGCACCGCGGACCGCTTCGTCGAGCACACCGGCATCCGGTGGTACCGGACGGGTGACATCGCCCGGTACCTGCCGG
ACGGCACGGTGGACTTCCTCGGCCGGCGCGACGACCAGGTGAAGATCCGCGGCTTCCGGGTCGAGCTGGGCGAGGTGGAG
GCAGCCCTGACCACGCTGCCGGAGGTCCGGGCGGGGGTGGCGGTGCTCGTGCGCGGCGCGTCCGGGCGGTCCGCCGTGCT
CGGCGGGGGCGTCGTGCTCGGCGCCGGCGTCGTGCCGGCCACCCCCGCCACGGGCGAGGCCGACGACGGCGGGGGCGGCG
GCGAGAGCTCCGGCGACGGCGCGGGCATCGCCGGCGCCGTGCGCGAGGGGCTGCGCCGCGCGCTGCCGCCGCACATGGTC
CCGGACCTGGTGGTCGCGCTCGACAGCCTGCCGCTCACCGCCAACGGGAAGATCGACCGCCGGGCGGTGACGGCCGCCGT
CGAGCGGGCGGTGGCCGGCCGGGCGGCCGACCACGCACCGCCGCGCACCGACCTGGAGCGGGTCGTGCACAACGTCTGGC
GCGAGGTGCTCGGGGTGGCCGAGTTCGGGATCACCGACGAGTTCTTCGCGCTGGGTGGTGACTCCGTCCTCGCCACCGCG
CTCGTCACGCGGCTGCGCGACGAGCTGGACACCGCCGCCGTCACCGTGCGCTCGGTGTTCGGGGCGCCGACCGTCGCCGC
GCTCGCCGAGCGGATCCGCGCCGCCGACACCGTCCCCGGCCGGGCGGAACGGGTCGCCGCGATCGCACTGGAGATCGCGG
CGATGTCGGACGACGAGGTCGCGGCCGAGCTGGTCGACCCGGACACGCTCCCCGCCGACTCCGGCGGTGCGTCGTGA

Upstream 100 bases:

>100_bases
GCCTCGACTACGTCGAGGCCAACTGGACCGATCTGCGTCCCCGCAGCCTGGTTGAGCAGATGGAGAAGGACGCGGCCGGC
TCCGACGTCTCCGCGTCGCG

Downstream 100 bases:

>100_bases
CCGCCCCGGCGCCGGCGCCGGTGGACGAGGGCTGGACGCGCTGGCCGGCGGAGCTCGAGCGGCGCTACCGGGACGCGGGG
TACTGGGGCGACCAGACCCT

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Mycobactin synthetase protein B [H]

Number of amino acids: Translated: 1678; Mature: 1678

Protein sequence:

>1678_residues
MRAQGSYRSRSVPLDQAPQAAAAGLARGLAAPFVLYERDGEWSCGSGVLAEVVLSATEVRHRTGSGDWRSEPTGATPLRQ
VANVLGGLEATGWRAYGWAAFELSLLLQGQPVPAGDDPLLHVIVPRREVRLIDGVAVLRAVDTADLAELAKLLAAVPSGP
PAASAPRAVVDLEHGVDEYRRIVAAAVADIRAERLRKVILSRVVPVAGDVDLVATYEVGRAGNNPARSFIVDTGHLRATG
FSPETVVEVSADGLVSTQPLAGTRALTGDPAVDRDLREVLLSDPKEIYEHAVSVQACQDELLQVCRPGSVVVDQFMNVLP
RGSVQHLASRVAGRLAAGRDAWDALGAVFPSITASGVPKPVACAVIGDYEGELRGLYSGAVLIADSDGGLDAALVLRTVF
QQDGRTWLRAGAGIVGHSDPDREAEETREKLRSVSRFLVAAPAAPAAPAVPAARAGTPGYQLEDVRRIVAELIDEDPSAI
GNEANLFELGLESIALMKAVGRWRRAGMAVSFAELAENPTVDGWCKLLSMRAPTEPAGADDGAQARAEAGEFPLALMQHA
YWVGRDGGQPLGEVAAHLYTEFDGAGVDVDRLRTAIEALVARHDMLRVRITDNGSQVVEATSGWRGLTVHDLRELGQAET
QARLAAVRDRMSHQMLDIEHGEVFATALSLLPQGRTRLHLDVDMVAADAVSYRVLLNDLARFYDRPGEEHPPLGYTYREY
RAARVPARRAAARAAAEWWQGRLPGLPGAPGLPRLASPDDAGTASSAGAASTAGATGSTGEPPRVTRRHFVLGPSARQAL
QRAAHSRGVTPAMAVATAFAEVLAGWSTESRFVLNVPMFDRDQVHADVNQVVGDFTSSVLLEVDLAEPQPFATRVRQVQA
RLHADAAHADYSGVEVLRDLTRRTGEQVLAPVVFTSALGLGELFGPGVRQHFGDPVWIISQGPQVLLDAQVTELDGGLLV
NWDVRDGEFAPGVVDAMFGAFERLVRGLADTAGTWDTAVDGLVPEPARAIRAAANDTAGPVPTRLLHEGFFENAVLAPDA
PALLWDTAGGPGSLAYGELRRRALGLAGALAGHGVRRGDLVGVSLPKGPSQVVAVLGVLAAGATYVPVGIEQPAARVERI
AAAAGFGVLITESHRDGVPAGVVQLAPDQPAEPAPVPDLAAPGELGGLDRPAYVLFTSGSTGQPKGVEVGHRAAMNTIAD
LIDRLGLGTDDRTLAVSALDFDLSVFDIFAPLSAGGAVALVDEDSRREASRWAELIRDHRVTVLNCVPTVLDLVLAAGVA
LGDSLRAVLLGGDKVGVDLPGRLAAAVPGCRFLGLGGTTETAIHSTICEVEGASPLPPQWRLVPYGTPLRNVRLRVVDPL
GRDCPDHVAGELWIGGDGVARGYLGDPERTADRFVEHTGIRWYRTGDIARYLPDGTVDFLGRRDDQVKIRGFRVELGEVE
AALTTLPEVRAGVAVLVRGASGRSAVLGGGVVLGAGVVPATPATGEADDGGGGGESSGDGAGIAGAVREGLRRALPPHMV
PDLVVALDSLPLTANGKIDRRAVTAAVERAVAGRAADHAPPRTDLERVVHNVWREVLGVAEFGITDEFFALGGDSVLATA
LVTRLRDELDTAAVTVRSVFGAPTVAALAERIRAADTVPGRAERVAAIALEIAAMSDDEVAAELVDPDTLPADSGGAS

Sequences:

>Translated_1678_residues
MRAQGSYRSRSVPLDQAPQAAAAGLARGLAAPFVLYERDGEWSCGSGVLAEVVLSATEVRHRTGSGDWRSEPTGATPLRQ
VANVLGGLEATGWRAYGWAAFELSLLLQGQPVPAGDDPLLHVIVPRREVRLIDGVAVLRAVDTADLAELAKLLAAVPSGP
PAASAPRAVVDLEHGVDEYRRIVAAAVADIRAERLRKVILSRVVPVAGDVDLVATYEVGRAGNNPARSFIVDTGHLRATG
FSPETVVEVSADGLVSTQPLAGTRALTGDPAVDRDLREVLLSDPKEIYEHAVSVQACQDELLQVCRPGSVVVDQFMNVLP
RGSVQHLASRVAGRLAAGRDAWDALGAVFPSITASGVPKPVACAVIGDYEGELRGLYSGAVLIADSDGGLDAALVLRTVF
QQDGRTWLRAGAGIVGHSDPDREAEETREKLRSVSRFLVAAPAAPAAPAVPAARAGTPGYQLEDVRRIVAELIDEDPSAI
GNEANLFELGLESIALMKAVGRWRRAGMAVSFAELAENPTVDGWCKLLSMRAPTEPAGADDGAQARAEAGEFPLALMQHA
YWVGRDGGQPLGEVAAHLYTEFDGAGVDVDRLRTAIEALVARHDMLRVRITDNGSQVVEATSGWRGLTVHDLRELGQAET
QARLAAVRDRMSHQMLDIEHGEVFATALSLLPQGRTRLHLDVDMVAADAVSYRVLLNDLARFYDRPGEEHPPLGYTYREY
RAARVPARRAAARAAAEWWQGRLPGLPGAPGLPRLASPDDAGTASSAGAASTAGATGSTGEPPRVTRRHFVLGPSARQAL
QRAAHSRGVTPAMAVATAFAEVLAGWSTESRFVLNVPMFDRDQVHADVNQVVGDFTSSVLLEVDLAEPQPFATRVRQVQA
RLHADAAHADYSGVEVLRDLTRRTGEQVLAPVVFTSALGLGELFGPGVRQHFGDPVWIISQGPQVLLDAQVTELDGGLLV
NWDVRDGEFAPGVVDAMFGAFERLVRGLADTAGTWDTAVDGLVPEPARAIRAAANDTAGPVPTRLLHEGFFENAVLAPDA
PALLWDTAGGPGSLAYGELRRRALGLAGALAGHGVRRGDLVGVSLPKGPSQVVAVLGVLAAGATYVPVGIEQPAARVERI
AAAAGFGVLITESHRDGVPAGVVQLAPDQPAEPAPVPDLAAPGELGGLDRPAYVLFTSGSTGQPKGVEVGHRAAMNTIAD
LIDRLGLGTDDRTLAVSALDFDLSVFDIFAPLSAGGAVALVDEDSRREASRWAELIRDHRVTVLNCVPTVLDLVLAAGVA
LGDSLRAVLLGGDKVGVDLPGRLAAAVPGCRFLGLGGTTETAIHSTICEVEGASPLPPQWRLVPYGTPLRNVRLRVVDPL
GRDCPDHVAGELWIGGDGVARGYLGDPERTADRFVEHTGIRWYRTGDIARYLPDGTVDFLGRRDDQVKIRGFRVELGEVE
AALTTLPEVRAGVAVLVRGASGRSAVLGGGVVLGAGVVPATPATGEADDGGGGGESSGDGAGIAGAVREGLRRALPPHMV
PDLVVALDSLPLTANGKIDRRAVTAAVERAVAGRAADHAPPRTDLERVVHNVWREVLGVAEFGITDEFFALGGDSVLATA
LVTRLRDELDTAAVTVRSVFGAPTVAALAERIRAADTVPGRAERVAAIALEIAAMSDDEVAAELVDPDTLPADSGGAS
>Mature_1678_residues
MRAQGSYRSRSVPLDQAPQAAAAGLARGLAAPFVLYERDGEWSCGSGVLAEVVLSATEVRHRTGSGDWRSEPTGATPLRQ
VANVLGGLEATGWRAYGWAAFELSLLLQGQPVPAGDDPLLHVIVPRREVRLIDGVAVLRAVDTADLAELAKLLAAVPSGP
PAASAPRAVVDLEHGVDEYRRIVAAAVADIRAERLRKVILSRVVPVAGDVDLVATYEVGRAGNNPARSFIVDTGHLRATG
FSPETVVEVSADGLVSTQPLAGTRALTGDPAVDRDLREVLLSDPKEIYEHAVSVQACQDELLQVCRPGSVVVDQFMNVLP
RGSVQHLASRVAGRLAAGRDAWDALGAVFPSITASGVPKPVACAVIGDYEGELRGLYSGAVLIADSDGGLDAALVLRTVF
QQDGRTWLRAGAGIVGHSDPDREAEETREKLRSVSRFLVAAPAAPAAPAVPAARAGTPGYQLEDVRRIVAELIDEDPSAI
GNEANLFELGLESIALMKAVGRWRRAGMAVSFAELAENPTVDGWCKLLSMRAPTEPAGADDGAQARAEAGEFPLALMQHA
YWVGRDGGQPLGEVAAHLYTEFDGAGVDVDRLRTAIEALVARHDMLRVRITDNGSQVVEATSGWRGLTVHDLRELGQAET
QARLAAVRDRMSHQMLDIEHGEVFATALSLLPQGRTRLHLDVDMVAADAVSYRVLLNDLARFYDRPGEEHPPLGYTYREY
RAARVPARRAAARAAAEWWQGRLPGLPGAPGLPRLASPDDAGTASSAGAASTAGATGSTGEPPRVTRRHFVLGPSARQAL
QRAAHSRGVTPAMAVATAFAEVLAGWSTESRFVLNVPMFDRDQVHADVNQVVGDFTSSVLLEVDLAEPQPFATRVRQVQA
RLHADAAHADYSGVEVLRDLTRRTGEQVLAPVVFTSALGLGELFGPGVRQHFGDPVWIISQGPQVLLDAQVTELDGGLLV
NWDVRDGEFAPGVVDAMFGAFERLVRGLADTAGTWDTAVDGLVPEPARAIRAAANDTAGPVPTRLLHEGFFENAVLAPDA
PALLWDTAGGPGSLAYGELRRRALGLAGALAGHGVRRGDLVGVSLPKGPSQVVAVLGVLAAGATYVPVGIEQPAARVERI
AAAAGFGVLITESHRDGVPAGVVQLAPDQPAEPAPVPDLAAPGELGGLDRPAYVLFTSGSTGQPKGVEVGHRAAMNTIAD
LIDRLGLGTDDRTLAVSALDFDLSVFDIFAPLSAGGAVALVDEDSRREASRWAELIRDHRVTVLNCVPTVLDLVLAAGVA
LGDSLRAVLLGGDKVGVDLPGRLAAAVPGCRFLGLGGTTETAIHSTICEVEGASPLPPQWRLVPYGTPLRNVRLRVVDPL
GRDCPDHVAGELWIGGDGVARGYLGDPERTADRFVEHTGIRWYRTGDIARYLPDGTVDFLGRRDDQVKIRGFRVELGEVE
AALTTLPEVRAGVAVLVRGASGRSAVLGGGVVLGAGVVPATPATGEADDGGGGGESSGDGAGIAGAVREGLRRALPPHMV
PDLVVALDSLPLTANGKIDRRAVTAAVERAVAGRAADHAPPRTDLERVVHNVWREVLGVAEFGITDEFFALGGDSVLATA
LVTRLRDELDTAAVTVRSVFGAPTVAALAERIRAADTVPGRAERVAAIALEIAAMSDDEVAAELVDPDTLPADSGGAS

Specific function: Involved in the initial steps of the mycobactin biosynthetic pathway. Putatively couples activated salicylic acid with serine or threonine and cyclizes this precursor to the hydroxyphenyloxazoline ring system present in this class of siderophores [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=474, Percent_Identity=25.7383966244726, Blast_Score=113, Evalue=2e-24,
Organism=Homo sapiens, GI187761345, Length=549, Percent_Identity=26.2295081967213, Blast_Score=94, Evalue=9e-19,
Organism=Homo sapiens, GI187761343, Length=549, Percent_Identity=26.2295081967213, Blast_Score=94, Evalue=9e-19,
Organism=Homo sapiens, GI38505220, Length=548, Percent_Identity=24.2700729927007, Blast_Score=91, Evalue=9e-18,
Organism=Homo sapiens, GI4758332, Length=327, Percent_Identity=25.3822629969419, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI12669909, Length=329, Percent_Identity=25.2279635258359, Blast_Score=86, Evalue=4e-16,
Organism=Homo sapiens, GI42794754, Length=349, Percent_Identity=27.7936962750716, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI42794752, Length=349, Percent_Identity=27.7936962750716, Blast_Score=83, Evalue=2e-15,
Organism=Escherichia coli, GI1786801, Length=647, Percent_Identity=32.6120556414219, Blast_Score=248, Evalue=2e-66,
Organism=Escherichia coli, GI1787518, Length=309, Percent_Identity=33.0097087378641, Blast_Score=128, Evalue=4e-30,
Organism=Escherichia coli, GI1786810, Length=523, Percent_Identity=24.4741873804971, Blast_Score=85, Evalue=4e-17,
Organism=Escherichia coli, GI1788114, Length=226, Percent_Identity=26.9911504424779, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI145693145, Length=545, Percent_Identity=25.3211009174312, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786809, Length=261, Percent_Identity=28.735632183908, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17556356, Length=577, Percent_Identity=25.8232235701906, Blast_Score=120, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17560308, Length=549, Percent_Identity=22.5865209471767, Blast_Score=85, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559526, Length=348, Percent_Identity=24.7126436781609, Blast_Score=74, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319591, Length=723, Percent_Identity=26.5560165975104, Blast_Score=205, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6320935, Length=223, Percent_Identity=33.6322869955157, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323182, Length=589, Percent_Identity=25.2971137521222, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24648676, Length=635, Percent_Identity=27.7165354330709, Blast_Score=154, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24656500, Length=392, Percent_Identity=25.2551020408163, Blast_Score=77, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648257, Length=409, Percent_Identity=24.6943765281174, Blast_Score=69, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013624
- InterPro:   IPR006163
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF08415 NRPS; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 176019; Mature: 176019

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAQGSYRSRSVPLDQAPQAAAAGLARGLAAPFVLYERDGEWSCGSGVLAEVVLSATEVR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
HRTGSGDWRSEPTGATPLRQVANVLGGLEATGWRAYGWAAFELSLLLQGQPVPAGDDPLL
HCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCEEEEEEEEECCCCCCCCCCEE
HVIVPRREVRLIDGVAVLRAVDTADLAELAKLLAAVPSGPPAASAPRAVVDLEHGVDEYR
EEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHCCHHHHH
RIVAAAVADIRAERLRKVILSRVVPVAGDVDLVATYEVGRAGNNPARSFIVDTGHLRATG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCEEECC
FSPETVVEVSADGLVSTQPLAGTRALTGDPAVDRDLREVLLSDPKEIYEHAVSVQACQDE
CCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLQVCRPGSVVVDQFMNVLPRGSVQHLASRVAGRLAAGRDAWDALGAVFPSITASGVPKP
HHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
VACAVIGDYEGELRGLYSGAVLIADSDGGLDAALVLRTVFQQDGRTWLRAGAGIVGHSDP
EEEEEEECCCCHHHEEECCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCC
DREAEETREKLRSVSRFLVAAPAAPAAPAVPAARAGTPGYQLEDVRRIVAELIDEDPSAI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHC
GNEANLFELGLESIALMKAVGRWRRAGMAVSFAELAENPTVDGWCKLLSMRAPTEPAGAD
CCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHCCCCHHHHHHHHHCCCCCCCCCCC
DGAQARAEAGEFPLALMQHAYWVGRDGGQPLGEVAAHLYTEFDGAGVDVDRLRTAIEALV
CCHHHHHHCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ARHDMLRVRITDNGSQVVEATSGWRGLTVHDLRELGQAETQARLAAVRDRMSHQMLDIEH
HHCCEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GEVFATALSLLPQGRTRLHLDVDMVAADAVSYRVLLNDLARFYDRPGEEHPPLGYTYREY
CHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
RAARVPARRAAARAAAEWWQGRLPGLPGAPGLPRLASPDDAGTASSAGAASTAGATGSTG
HHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EPPRVTRRHFVLGPSARQALQRAAHSRGVTPAMAVATAFAEVLAGWSTESRFVLNVPMFD
CCCCCCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
RDQVHADVNQVVGDFTSSVLLEVDLAEPQPFATRVRQVQARLHADAAHADYSGVEVLRDL
CHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TRRTGEQVLAPVVFTSALGLGELFGPGVRQHFGDPVWIISQGPQVLLDAQVTELDGGLLV
HHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHCCCCEEEEECCCCEEEECEEEECCCCEEE
NWDVRDGEFAPGVVDAMFGAFERLVRGLADTAGTWDTAVDGLVPEPARAIRAAANDTAGP
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHCCCCCCC
VPTRLLHEGFFENAVLAPDAPALLWDTAGGPGSLAYGELRRRALGLAGALAGHGVRRGDL
CHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
VGVSLPKGPSQVVAVLGVLAAGATYVPVGIEQPAARVERIAAAAGFGVLITESHRDGVPA
EEEECCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCC
GVVQLAPDQPAEPAPVPDLAAPGELGGLDRPAYVLFTSGSTGQPKGVEVGHRAAMNTIAD
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
LIDRLGLGTDDRTLAVSALDFDLSVFDIFAPLSAGGAVALVDEDSRREASRWAELIRDHR
HHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCC
VTVLNCVPTVLDLVLAAGVALGDSLRAVLLGGDKVGVDLPGRLAAAVPGCRFLGLGGTTE
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCCHHHHHCCCCEEEECCCCHH
TAIHSTICEVEGASPLPPQWRLVPYGTPLRNVRLRVVDPLGRDCPDHVAGELWIGGDGVA
HHHHHHHHHCCCCCCCCCCCEEEECCCCHHHCEEEEECCCCCCCCHHHCCEEEECCCCCC
RGYLGDPERTADRFVEHTGIRWYRTGDIARYLPDGTVDFLGRRDDQVKIRGFRVELGEVE
CCCCCCCHHHHHHHHHHCCCEEEECCCHHHHCCCCCHHHHCCCCCEEEEEEEEEEHHHHH
AALTTLPEVRAGVAVLVRGASGRSAVLGGGVVLGAGVVPATPATGEADDGGGGGESSGDG
HHHHHHHHHHCCEEEEEECCCCCCEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
AGIAGAVREGLRRALPPHMVPDLVVALDSLPLTANGKIDRRAVTAAVERAVAGRAADHAP
CCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
PRTDLERVVHNVWREVLGVAEFGITDEFFALGGDSVLATALVTRLRDELDTAAVTVRSVF
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GAPTVAALAERIRAADTVPGRAERVAAIALEIAAMSDDEVAAELVDPDTLPADSGGAS
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRAQGSYRSRSVPLDQAPQAAAAGLARGLAAPFVLYERDGEWSCGSGVLAEVVLSATEVR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
HRTGSGDWRSEPTGATPLRQVANVLGGLEATGWRAYGWAAFELSLLLQGQPVPAGDDPLL
HCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCEEEEEEEEECCCCCCCCCCEE
HVIVPRREVRLIDGVAVLRAVDTADLAELAKLLAAVPSGPPAASAPRAVVDLEHGVDEYR
EEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHCCHHHHH
RIVAAAVADIRAERLRKVILSRVVPVAGDVDLVATYEVGRAGNNPARSFIVDTGHLRATG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCEEECC
FSPETVVEVSADGLVSTQPLAGTRALTGDPAVDRDLREVLLSDPKEIYEHAVSVQACQDE
CCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLQVCRPGSVVVDQFMNVLPRGSVQHLASRVAGRLAAGRDAWDALGAVFPSITASGVPKP
HHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
VACAVIGDYEGELRGLYSGAVLIADSDGGLDAALVLRTVFQQDGRTWLRAGAGIVGHSDP
EEEEEEECCCCHHHEEECCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCC
DREAEETREKLRSVSRFLVAAPAAPAAPAVPAARAGTPGYQLEDVRRIVAELIDEDPSAI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHC
GNEANLFELGLESIALMKAVGRWRRAGMAVSFAELAENPTVDGWCKLLSMRAPTEPAGAD
CCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHCCCCHHHHHHHHHCCCCCCCCCCC
DGAQARAEAGEFPLALMQHAYWVGRDGGQPLGEVAAHLYTEFDGAGVDVDRLRTAIEALV
CCHHHHHHCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ARHDMLRVRITDNGSQVVEATSGWRGLTVHDLRELGQAETQARLAAVRDRMSHQMLDIEH
HHCCEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GEVFATALSLLPQGRTRLHLDVDMVAADAVSYRVLLNDLARFYDRPGEEHPPLGYTYREY
CHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
RAARVPARRAAARAAAEWWQGRLPGLPGAPGLPRLASPDDAGTASSAGAASTAGATGSTG
HHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EPPRVTRRHFVLGPSARQALQRAAHSRGVTPAMAVATAFAEVLAGWSTESRFVLNVPMFD
CCCCCCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
RDQVHADVNQVVGDFTSSVLLEVDLAEPQPFATRVRQVQARLHADAAHADYSGVEVLRDL
CHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TRRTGEQVLAPVVFTSALGLGELFGPGVRQHFGDPVWIISQGPQVLLDAQVTELDGGLLV
HHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHCCCCEEEEECCCCEEEECEEEECCCCEEE
NWDVRDGEFAPGVVDAMFGAFERLVRGLADTAGTWDTAVDGLVPEPARAIRAAANDTAGP
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHCCCCCCC
VPTRLLHEGFFENAVLAPDAPALLWDTAGGPGSLAYGELRRRALGLAGALAGHGVRRGDL
CHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
VGVSLPKGPSQVVAVLGVLAAGATYVPVGIEQPAARVERIAAAAGFGVLITESHRDGVPA
EEEECCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCC
GVVQLAPDQPAEPAPVPDLAAPGELGGLDRPAYVLFTSGSTGQPKGVEVGHRAAMNTIAD
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
LIDRLGLGTDDRTLAVSALDFDLSVFDIFAPLSAGGAVALVDEDSRREASRWAELIRDHR
HHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCC
VTVLNCVPTVLDLVLAAGVALGDSLRAVLLGGDKVGVDLPGRLAAAVPGCRFLGLGGTTE
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCCHHHHHCCCCEEEECCCCHH
TAIHSTICEVEGASPLPPQWRLVPYGTPLRNVRLRVVDPLGRDCPDHVAGELWIGGDGVA
HHHHHHHHHCCCCCCCCCCCEEEECCCCHHHCEEEEECCCCCCCCHHHCCEEEECCCCCC
RGYLGDPERTADRFVEHTGIRWYRTGDIARYLPDGTVDFLGRRDDQVKIRGFRVELGEVE
CCCCCCCHHHHHHHHHHCCCEEEECCCHHHHCCCCCHHHHCCCCCEEEEEEEEEEHHHHH
AALTTLPEVRAGVAVLVRGASGRSAVLGGGVVLGAGVVPATPATGEADDGGGGGESSGDG
HHHHHHHHHHCCEEEEEECCCCCCEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
AGIAGAVREGLRRALPPHMVPDLVVALDSLPLTANGKIDRRAVTAAVERAVAGRAADHAP
CCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
PRTDLERVVHNVWREVLGVAEFGITDEFFALGGDSVLATALVTRLRDELDTAAVTVRSVF
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GAPTVAALAERIRAADTVPGRAERVAAIALEIAAMSDDEVAAELVDPDTLPADSGGAS
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]