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The map label for this gene is birA [H]

Identifier: 158317655

GI number: 158317655

Start: 7183328

End: 7184257

Strand: Reverse

Name: birA [H]

Synonym: Franean1_5913

Alternate gene names: 158317655

Gene position: 7184257-7183328 (Counterclockwise)

Preceding gene: 158317660

Following gene: 158317654

Centisome position: 79.98

GC content: 76.24

Gene sequence:

>930_bases
GTGCCAGTGCATCCCGCCGAATCCCCCGGGCGGCGAACGGCCCCTGTCGAGCCGGCCATCTCGCCCCCTGTCGCAGGTCA
CAGCCCAGCCCCGGCGGTGCCGCCAGGGGCACGACGGCCGCTGGACACCGACACTCTCCGCCCGCTCGCCGCCCGCCTCG
GGCTGGCGCTCGCCGTCGTCGACGAGATCGACTCGACCAACGCCGAGCTCGGACGGATCGCCCGCGGCCTGCCCGGCGCG
GTGGGACTGCCCGCGGTCACCCGCCCGCCCACGGTTACGGACGGTGCCCCGGCCGGGCTTGTGCTCGCCGCCGAGCGGCA
GACCGCGGGCCGCGGGCGGCTCGACCGCTCCTGGGAGTCAGCGGCCGGCGCCGGGCTCATGGTGTCCGTGCTGGTGCGCC
CCGAGATCGAGCCCCGGTGGCTCGGCTGGCTGCCGATGGTCGTCGGCACCTCGCTCGTACGCACGCTGCGCAGGTACGCG
GGCGTGCCCGCGGTGCTGAAATGGCCGAACGACGTGCAGGTCGACGGGGCGAAGCTCGCCGGCATTCTCGTGGAGCTGGC
GCCGAGCCCTGCTGTGCCGCCGGCGGCCGTAATCGGGTTCGGGCTGAACGTCACCGCCCGCGCCGCGGAGCTGCCGCCGC
GCTCCACCAGCCTGCTGCTGCTCGGCGCCGACCCCGCCCGCCTGGACCGCTCCGCCCTGCTCGGCGCCCTGCTGACCGAC
CTCGTCGATGCGTTGGGCCGGTGGGAGGCGGCGCCCGAGCGGGCCCGCGGGGAGTACCGCGACACGTGCGCCACGCTGGG
CCGGCGGGTCCGCGTCGAGCTTCCGGACGGGACGTCCACGCACGGCACGGCGACCGACGTCGACGAGCTCGGCCGGCTCA
TCGTCGACGGGCAGGCGTTCAGTGCCGCCGACATCGTCCATCTGCGCTGA

Upstream 100 bases:

>100_bases
GAAGCCGGGAGAGCCATACCGCGAAGCGTACGGCGGTCGGTGGTCCACGTGCTCGATTGATGTGGAGACCGTCTCACCAT
GCCTCTGGGAAGGTGGTCCC

Downstream 100 bases:

>100_bases
CGACGGCTGTGTTGTGCCAGCTGGGGGCGGCCCACCGGTGTGCCGCGGTCGTCCGGGATGCGACGATCAGGCGGTGGCGT
TCCCCGACGACGTTCTGACC

Product: biotin--acetyl-CoA-carboxylase ligase

Products: NA

Alternate protein names: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase; Biotin--protein ligase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MPVHPAESPGRRTAPVEPAISPPVAGHSPAPAVPPGARRPLDTDTLRPLAARLGLALAVVDEIDSTNAELGRIARGLPGA
VGLPAVTRPPTVTDGAPAGLVLAAERQTAGRGRLDRSWESAAGAGLMVSVLVRPEIEPRWLGWLPMVVGTSLVRTLRRYA
GVPAVLKWPNDVQVDGAKLAGILVELAPSPAVPPAAVIGFGLNVTARAAELPPRSTSLLLLGADPARLDRSALLGALLTD
LVDALGRWEAAPERARGEYRDTCATLGRRVRVELPDGTSTHGTATDVDELGRLIVDGQAFSAADIVHLR

Sequences:

>Translated_309_residues
MPVHPAESPGRRTAPVEPAISPPVAGHSPAPAVPPGARRPLDTDTLRPLAARLGLALAVVDEIDSTNAELGRIARGLPGA
VGLPAVTRPPTVTDGAPAGLVLAAERQTAGRGRLDRSWESAAGAGLMVSVLVRPEIEPRWLGWLPMVVGTSLVRTLRRYA
GVPAVLKWPNDVQVDGAKLAGILVELAPSPAVPPAAVIGFGLNVTARAAELPPRSTSLLLLGADPARLDRSALLGALLTD
LVDALGRWEAAPERARGEYRDTCATLGRRVRVELPDGTSTHGTATDVDELGRLIVDGQAFSAADIVHLR
>Mature_308_residues
PVHPAESPGRRTAPVEPAISPPVAGHSPAPAVPPGARRPLDTDTLRPLAARLGLALAVVDEIDSTNAELGRIARGLPGAV
GLPAVTRPPTVTDGAPAGLVLAAERQTAGRGRLDRSWESAAGAGLMVSVLVRPEIEPRWLGWLPMVVGTSLVRTLRRYAG
VPAVLKWPNDVQVDGAKLAGILVELAPSPAVPPAAVIGFGLNVTARAAELPPRSTSLLLLGADPARLDRSALLGALLTDL
VDALGRWEAAPERARGEYRDTCATLGRRVRVELPDGTSTHGTATDVDELGRLIVDGQAFSAADIVHLR

Specific function: BirA acts both as a biotin-operon repressor and as the enzyme that synthesizes the corepressor, acetyl-CoA:carbon-dioxide ligase. This protein also activates biotin to form biotinyl-5'- adenylate and transfers the biotin moiety to biotin-accepting protein

COG id: COG0340

COG function: function code H; Biotin-(acetyl-CoA carboxylase) ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the biotin--protein ligase family [H]

Homologues:

Organism=Escherichia coli, GI1790408, Length=196, Percent_Identity=33.6734693877551, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =6.3.4.15 [H]

Molecular weight: Translated: 32154; Mature: 32023

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVHPAESPGRRTAPVEPAISPPVAGHSPAPAVPPGARRPLDTDTLRPLAARLGLALAVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DEIDSTNAELGRIARGLPGAVGLPAVTRPPTVTDGAPAGLVLAAERQTAGRGRLDRSWES
HHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHH
AAGAGLMVSVLVRPEIEPRWLGWLPMVVGTSLVRTLRRYAGVPAVLKWPNDVQVDGAKLA
HCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEECHHHHE
GILVELAPSPAVPPAAVIGFGLNVTARAAELPPRSTSLLLLGADPARLDRSALLGALLTD
EEHEEECCCCCCCCHHHHCCCCCCEEHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
LVDALGRWEAAPERARGEYRDTCATLGRRVRVELPDGTSTHGTATDVDELGRLIVDGQAF
HHHHHHHCCCCCHHHCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHEEECCCCC
SAADIVHLR
CCCCEEECC
>Mature Secondary Structure 
PVHPAESPGRRTAPVEPAISPPVAGHSPAPAVPPGARRPLDTDTLRPLAARLGLALAVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DEIDSTNAELGRIARGLPGAVGLPAVTRPPTVTDGAPAGLVLAAERQTAGRGRLDRSWES
HHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHH
AAGAGLMVSVLVRPEIEPRWLGWLPMVVGTSLVRTLRRYAGVPAVLKWPNDVQVDGAKLA
HCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEECHHHHE
GILVELAPSPAVPPAAVIGFGLNVTARAAELPPRSTSLLLLGADPARLDRSALLGALLTD
EEHEEECCCCCCCCHHHHCCCCCCEEHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
LVDALGRWEAAPERARGEYRDTCATLGRRVRVELPDGTSTHGTATDVDELGRLIVDGQAF
HHHHHHHCCCCCHHHCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHEEECCCCC
SAADIVHLR
CCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7730294 [H]