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The map label for this gene is patA [H]

Identifier: 158317509

GI number: 158317509

Start: 6997857

End: 6999173

Strand: Reverse

Name: patA [H]

Synonym: Franean1_5761

Alternate gene names: 158317509

Gene position: 6999173-6997857 (Counterclockwise)

Preceding gene: 158317510

Following gene: 158317508

Centisome position: 77.92

GC content: 71.98

Gene sequence:

>1317_bases
GTGACCCGGGTCGAGGCGCGGCCTGCGGCCGGCGGCCAGGCCGGTAGCGCTGTCGGGAGCGAGGTCGAGGTGCTCGACCT
TTACCGGGCGCACCTCAGCAAGGGCAGGGCGACGCTGGCGGAGCTGTTCGGCGCCCACATGGAGGTCGAGTCCCGCGGCG
CCTGGTTGACTACCAGTGACGGGGAGCGGTTCCTCAACGCCGGCGGCTACGGGGTGTTCATCATGGGCAGCCGTCACCCC
ACCGTCGTGGCGGCGGTGGAGCGCCAGCTCCGGACCCATCCGGTGGCGACCCGCATCCTGCTCGAACCCACCGTGGCGCG
GGCTGCGGAAGCGCTGGTCTCGGTCGTCCCCGCCGGCCTGAGCCGGGTGCACTTCTCACTGTCGGGCGCGGAAGCCGTCG
AGACCGCGCTGAAGCTGGCTCGCGCGAGCGGCCGCACCCGCACGGTCTCGATGCTCGGCGGCTACCACGGCAAGACCCTT
GGAGCGCTGTCCGCGACCGCGAAGGAGGTCTACCAGAAGCCCTTCCGGCCACTGGTGCCCGACTTCGTGCACCTCCCGTT
CGGCGACGCCGACGCGCTCGCGGCGGAGCTGGCGGCTCGGCCGGGCGAAGTCTGCGTGATCCTCGAACCGGTGCAGGGCG
AGGGCGGCGTGGTCATCCCGCCAGCCGGTTTCCTCGCCGACGTCGAGAAGCTCGTCCGCCACTACGACGGGTTCCTCGTC
CTGGACGAGGTGCAGTCGGGCTTCGGTCGGCTCGGTCGCTGGTGGGGCGCCGACGCCGAAGGCGTCGTCCCGGACGTCCT
GGTGACCGGCAAAGCGCTCGGCGGCGGCGTGGTCCCGGTGTCGGCGGCGGTGGCCACCCGGCAGGCCTTCCGGCCCTTCG
ACAAGGACCCCTACGTCCACACGTCGACGTTCTCCGGCCAGCCGTTGCTGATGGCCGCGGTGCGGGCCGCCGTCCAGGTG
ATGAAGGAGGAGGACCTGGTGCGGCGGGCGGCCGACCTCGGCGCCCGGCTGCTGCCGCGCCTCGACGAGATAGCCCGTCA
CAACATCGCCGACCAGCTCGTCGAGGTCCGCGGCGAGGGCCTGCTGATCGGCGTCGAGCTGGTCGAGGCGGGGCTGGCCG
GGGAGCTGCTGATCGAGCTGTTCAACCACGGCGTCGTCGCCAACCACTCCATGAACGGCAGCGCGGTGGTCCGGTTCACC
CCGCCGGCCATCCTGACCGACCGCGACGTGGAGTTCTTGCTCGCATCCTTCGACAAGGCCACCCGAGCGCTGGTCAGCGG
CTCGGCCACCATGCCTGGAAGGCGGAGCCGATCGTGA

Upstream 100 bases:

>100_bases
TGGCGAGCGCGGTGCGGCCGCTCGCCTTCCATCCGCCAGGCCGCGGGTCCGCGGCGGGCCCGCTGCTGGCCTGGTTCGCC
GGCGCCCCGCTGGAGCTGGC

Downstream 100 bases:

>100_bases
GGCACGTAGAACTCGACGCCGTGGTGCGCGGCGCGCTCGCCACCGACGTCTTCGACGAGGTCCTGCGGTGGGAGCGTTAC
CCCGATCTCGCGCCGCACGT

Product: class III aminotransferase

Products: NA

Alternate protein names: Putrescine--2-oxoglutaric acid transaminase; PAT; PATase [H]

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MTRVEARPAAGGQAGSAVGSEVEVLDLYRAHLSKGRATLAELFGAHMEVESRGAWLTTSDGERFLNAGGYGVFIMGSRHP
TVVAAVERQLRTHPVATRILLEPTVARAAEALVSVVPAGLSRVHFSLSGAEAVETALKLARASGRTRTVSMLGGYHGKTL
GALSATAKEVYQKPFRPLVPDFVHLPFGDADALAAELAARPGEVCVILEPVQGEGGVVIPPAGFLADVEKLVRHYDGFLV
LDEVQSGFGRLGRWWGADAEGVVPDVLVTGKALGGGVVPVSAAVATRQAFRPFDKDPYVHTSTFSGQPLLMAAVRAAVQV
MKEEDLVRRAADLGARLLPRLDEIARHNIADQLVEVRGEGLLIGVELVEAGLAGELLIELFNHGVVANHSMNGSAVVRFT
PPAILTDRDVEFLLASFDKATRALVSGSATMPGRRSRS

Sequences:

>Translated_438_residues
MTRVEARPAAGGQAGSAVGSEVEVLDLYRAHLSKGRATLAELFGAHMEVESRGAWLTTSDGERFLNAGGYGVFIMGSRHP
TVVAAVERQLRTHPVATRILLEPTVARAAEALVSVVPAGLSRVHFSLSGAEAVETALKLARASGRTRTVSMLGGYHGKTL
GALSATAKEVYQKPFRPLVPDFVHLPFGDADALAAELAARPGEVCVILEPVQGEGGVVIPPAGFLADVEKLVRHYDGFLV
LDEVQSGFGRLGRWWGADAEGVVPDVLVTGKALGGGVVPVSAAVATRQAFRPFDKDPYVHTSTFSGQPLLMAAVRAAVQV
MKEEDLVRRAADLGARLLPRLDEIARHNIADQLVEVRGEGLLIGVELVEAGLAGELLIELFNHGVVANHSMNGSAVVRFT
PPAILTDRDVEFLLASFDKATRALVSGSATMPGRRSRS
>Mature_437_residues
TRVEARPAAGGQAGSAVGSEVEVLDLYRAHLSKGRATLAELFGAHMEVESRGAWLTTSDGERFLNAGGYGVFIMGSRHPT
VVAAVERQLRTHPVATRILLEPTVARAAEALVSVVPAGLSRVHFSLSGAEAVETALKLARASGRTRTVSMLGGYHGKTLG
ALSATAKEVYQKPFRPLVPDFVHLPFGDADALAAELAARPGEVCVILEPVQGEGGVVIPPAGFLADVEKLVRHYDGFLVL
DEVQSGFGRLGRWWGADAEGVVPDVLVTGKALGGGVVPVSAAVATRQAFRPFDKDPYVHTSTFSGQPLLMAAVRAAVQVM
KEEDLVRRAADLGARLLPRLDEIARHNIADQLVEVRGEGLLIGVELVEAGLAGELLIELFNHGVVANHSMNGSAVVRFTP
PAILTDRDVEFLLASFDKATRALVSGSATMPGRRSRS

Specific function: Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithi

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=371, Percent_Identity=30.188679245283, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI284507298, Length=294, Percent_Identity=33.6734693877551, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI13994255, Length=449, Percent_Identity=27.1714922048998, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI37574042, Length=406, Percent_Identity=28.5714285714286, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226442709, Length=380, Percent_Identity=29.4736842105263, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI226442705, Length=406, Percent_Identity=28.0788177339901, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI24119277, Length=402, Percent_Identity=26.3681592039801, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI188536080, Length=429, Percent_Identity=24.4755244755245, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI38679950, Length=429, Percent_Identity=24.4755244755245, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI38679946, Length=429, Percent_Identity=24.4755244755245, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI145693181, Length=417, Percent_Identity=37.8896882494005, Blast_Score=288, Evalue=3e-79,
Organism=Escherichia coli, GI1789759, Length=387, Percent_Identity=31.5245478036176, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1788044, Length=389, Percent_Identity=32.9048843187661, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1787560, Length=418, Percent_Identity=30.3827751196172, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1789016, Length=395, Percent_Identity=29.620253164557, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1786991, Length=400, Percent_Identity=27.25, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786349, Length=314, Percent_Identity=29.6178343949045, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32564660, Length=407, Percent_Identity=30.4668304668305, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI25144271, Length=370, Percent_Identity=28.6486486486486, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI25144274, Length=260, Percent_Identity=32.3076923076923, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71992977, Length=409, Percent_Identity=27.6283618581907, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17541228, Length=437, Percent_Identity=23.3409610983982, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6323470, Length=389, Percent_Identity=32.133676092545, Blast_Score=173, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6324432, Length=387, Percent_Identity=27.906976744186, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21357415, Length=382, Percent_Identity=29.5811518324607, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI161085790, Length=482, Percent_Identity=29.045643153527, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21356575, Length=414, Percent_Identity=28.5024154589372, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28574759, Length=466, Percent_Identity=28.9699570815451, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI281366494, Length=452, Percent_Identity=21.0176991150442, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24667139, Length=452, Percent_Identity=21.0176991150442, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24667143, Length=452, Percent_Identity=21.0176991150442, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR017747
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.82 [H]

Molecular weight: Translated: 46346; Mature: 46215

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVEARPAAGGQAGSAVGSEVEVLDLYRAHLSKGRATLAELFGAHMEVESRGAWLTTSD
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCEEECCC
GERFLNAGGYGVFIMGSRHPTVVAAVERQLRTHPVATRILLEPTVARAAEALVSVVPAGL
CHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHEEECHHHHHHHHHHHHHHHCCH
SRVHFSLSGAEAVETALKLARASGRTRTVSMLGGYHGKTLGALSATAKEVYQKPFRPLVP
HHEEEECCCHHHHHHHHHHHHHCCCCEEEHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
DFVHLPFGDADALAAELAARPGEVCVILEPVQGEGGVVIPPAGFLADVEKLVRHYDGFLV
HHEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHCCEEE
LDEVQSGFGRLGRWWGADAEGVVPDVLVTGKALGGGVVPVSAAVATRQAFRPFDKDPYVH
EHHHHHHHHHHHHHCCCCCCCCCCHHEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCEE
TSTFSGQPLLMAAVRAAVQVMKEEDLVRRAADLGARLLPRLDEIARHNIADQLVEVRGEG
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLIGVELVEAGLAGELLIELFNHGVVANHSMNGSAVVRFTPPAILTDRDVEFLLASFDKA
EEEEHHHHHCCCHHHHHHHHHHCCEEEECCCCCCEEEEECCCCEECCCCHHHHHHHHHHH
TRALVSGSATMPGRRSRS
HHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TRVEARPAAGGQAGSAVGSEVEVLDLYRAHLSKGRATLAELFGAHMEVESRGAWLTTSD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCEEECCC
GERFLNAGGYGVFIMGSRHPTVVAAVERQLRTHPVATRILLEPTVARAAEALVSVVPAGL
CHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHEEECHHHHHHHHHHHHHHHCCH
SRVHFSLSGAEAVETALKLARASGRTRTVSMLGGYHGKTLGALSATAKEVYQKPFRPLVP
HHEEEECCCHHHHHHHHHHHHHCCCCEEEHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
DFVHLPFGDADALAAELAARPGEVCVILEPVQGEGGVVIPPAGFLADVEKLVRHYDGFLV
HHEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHCCEEE
LDEVQSGFGRLGRWWGADAEGVVPDVLVTGKALGGGVVPVSAAVATRQAFRPFDKDPYVH
EHHHHHHHHHHHHHCCCCCCCCCCHHEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCEE
TSTFSGQPLLMAAVRAAVQVMKEEDLVRRAADLGARLLPRLDEIARHNIADQLVEVRGEG
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLIGVELVEAGLAGELLIELFNHGVVANHSMNGSAVVRFTPPAILTDRDVEFLLASFDKA
EEEEHHHHHCCCHHHHHHHHHHCCEEEECCCCCCEEEEECCCCEECCCCHHHHHHHHHHH
TRALVSGSATMPGRRSRS
HHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA