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The map label for this gene is murI

Identifier: 158317397

GI number: 158317397

Start: 6861682

End: 6862512

Strand: Direct

Name: murI

Synonym: Franean1_5648

Alternate gene names: 158317397

Gene position: 6861682-6862512 (Clockwise)

Preceding gene: 158317395

Following gene: 158317398

Centisome position: 76.39

GC content: 69.92

Gene sequence:

>831_bases
ATGAGCGGCGCGCCCATCGGGGTGTTCGACAGTGGAGTCGGCGGTCTCACCGTTGCGCGCGCGATCCTGGACCAGCTGCC
AGGAGAGTCGCTGCTCTACATCGGCGACACCGCGCACGCCCCCTACGGGCCGCGACCGATTGCCGAGGTGCGCCGGTACG
CCCTCGCCGCACTGGACGAACTCGTCTCCGCGGGTGTGAAACTTCTTGTCATCGCGTGCAATTCCGCGAGCGCGGCATGC
CTGCGCGATGCCCGGGAACGCTACGACGTACCGGTGGTCGAGGTCATCGTGCCCGCGACCCGCCGTGCCGTCGCGGCAAC
ACGGAGTGGTCGAGTGGGAGTCATCGGAACGGTCGCCACGATCACCAGCCGGGCCTACGAGGACGCCTTCGCGGCGGCCG
CGGGCACCGAGCTGGTCAGCGTGGCGTGCCCGGCCTTCGTCGATTTCGTCGAGCGCGGCATCACGTCCGGCCGGCAGTTG
CTGGGACTCACCGAGGCGTATCTGGCACCGTTGCAGGAAGCCGACGTCGACACAGTGATTCTCGGATGCACCCACTATCC
ACTGTTGACCGGCGTCATCGGTCTCGTCATGGGAGAGGGCGTCACACTGGTGAGCAGCGCCGAGGAGACGGCCAAGGACA
CCTACCGGGTGCTCGCCCGCGACGGCCTCTTCCGCGACCCCGACCTGCCGCCCCCGGCGCATCGCTTCCTGACCACCGGT
GATCCCGCCGCGTTCGCGCGGGTGGGCCGCCGTTTCCTGGGCCCCGAGATCACGGCGGTGAGCATCGCCCCGGCGGCGGC
CCCCCGGCAGGCACAGGCGGTGGGACGATGA

Upstream 100 bases:

>100_bases
CGGGCATGTCCGCGACGAGACGCCTGTCCGGGATCGGACATTGGTTTCGTGATGACAGCCACAGGGTGAGCAGCAGGTTT
CCGGCTTAGTCTCATCGCTC

Downstream 100 bases:

>100_bases
AACTGACGATCCTGGGCTGTTCCGGCACCTACCCGGGCCCCGCTTCGGCCTGCTCCTCCTACCTGATCGAGGACGAGGGC
TTCCGGCTCGTCCTGGACGC

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSGAPIGVFDSGVGGLTVARAILDQLPGESLLYIGDTAHAPYGPRPIAEVRRYALAALDELVSAGVKLLVIACNSASAAC
LRDARERYDVPVVEVIVPATRRAVAATRSGRVGVIGTVATITSRAYEDAFAAAAGTELVSVACPAFVDFVERGITSGRQL
LGLTEAYLAPLQEADVDTVILGCTHYPLLTGVIGLVMGEGVTLVSSAEETAKDTYRVLARDGLFRDPDLPPPAHRFLTTG
DPAAFARVGRRFLGPEITAVSIAPAAAPRQAQAVGR

Sequences:

>Translated_276_residues
MSGAPIGVFDSGVGGLTVARAILDQLPGESLLYIGDTAHAPYGPRPIAEVRRYALAALDELVSAGVKLLVIACNSASAAC
LRDARERYDVPVVEVIVPATRRAVAATRSGRVGVIGTVATITSRAYEDAFAAAAGTELVSVACPAFVDFVERGITSGRQL
LGLTEAYLAPLQEADVDTVILGCTHYPLLTGVIGLVMGEGVTLVSSAEETAKDTYRVLARDGLFRDPDLPPPAHRFLTTG
DPAAFARVGRRFLGPEITAVSIAPAAAPRQAQAVGR
>Mature_275_residues
SGAPIGVFDSGVGGLTVARAILDQLPGESLLYIGDTAHAPYGPRPIAEVRRYALAALDELVSAGVKLLVIACNSASAACL
RDARERYDVPVVEVIVPATRRAVAATRSGRVGVIGTVATITSRAYEDAFAAAAGTELVSVACPAFVDFVERGITSGRQLL
GLTEAYLAPLQEADVDTVILGCTHYPLLTGVIGLVMGEGVTLVSSAEETAKDTYRVLARDGLFRDPDLPPPAHRFLTTGD
PAAFARVGRRFLGPEITAVSIAPAAAPRQAQAVGR

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=221, Percent_Identity=34.3891402714932, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_FRASN (A8L764)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001509905.1
- ProteinModelPortal:   A8L764
- SMR:   A8L764
- GeneID:   5673975
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_5648
- HOGENOM:   HBG645102
- OMA:   AILGCTH
- ProtClustDB:   PRK00865
- BioCyc:   FSP1855:FRANEAN1_5648-MONOMER
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 28708; Mature: 28577

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGAPIGVFDSGVGGLTVARAILDQLPGESLLYIGDTAHAPYGPRPIAEVRRYALAALDE
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LVSAGVKLLVIACNSASAACLRDARERYDVPVVEVIVPATRRAVAATRSGRVGVIGTVAT
HHHCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCEEEEEHHHH
ITSRAYEDAFAAAAGTELVSVACPAFVDFVERGITSGRQLLGLTEAYLAPLQEADVDTVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHCCCCEEE
LGCTHYPLLTGVIGLVMGEGVTLVSSAEETAKDTYRVLARDGLFRDPDLPPPAHRFLTTG
ECCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCC
DPAAFARVGRRFLGPEITAVSIAPAAAPRQAQAVGR
CHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCCC
>Mature Secondary Structure 
SGAPIGVFDSGVGGLTVARAILDQLPGESLLYIGDTAHAPYGPRPIAEVRRYALAALDE
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LVSAGVKLLVIACNSASAACLRDARERYDVPVVEVIVPATRRAVAATRSGRVGVIGTVAT
HHHCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCEEEEEHHHH
ITSRAYEDAFAAAAGTELVSVACPAFVDFVERGITSGRQLLGLTEAYLAPLQEADVDTVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHCCCCEEE
LGCTHYPLLTGVIGLVMGEGVTLVSSAEETAKDTYRVLARDGLFRDPDLPPPAHRFLTTG
ECCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCC
DPAAFARVGRRFLGPEITAVSIAPAAAPRQAQAVGR
CHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA