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The map label for this gene is yqeC [H]

Identifier: 158317356

GI number: 158317356

Start: 6801545

End: 6802567

Strand: Direct

Name: yqeC [H]

Synonym: Franean1_5606

Alternate gene names: 158317356

Gene position: 6801545-6802567 (Clockwise)

Preceding gene: 158317354

Following gene: 158317358

Centisome position: 75.72

GC content: 71.46

Gene sequence:

>1023_bases
ATGCAGCTCGGAATGATCGGACTCGGCCGGATGGGCGCGAACCTCGTCCGCCGGCTGATGCGCGACGGGCACGAATGTGT
GGTCTACGACGTGAACCCCGAGACGGTGAAGTCGCTGGCCGCCGAGGGCGCCGTCGGCGTCAACTCGCTGGCCGACTTCG
CGGCCGCGCTGAGCACCCCGCGGGCGGCCTGGGTCATGGTGCCCGCGGGCCTGACCGGCCAGACCGTCTTCGAGCTCGCG
GAGCACTTCGAGGCCGGCGACATCATCATCGACGGCGGCAACTCCTACTACCGCGACGACGTCGACCGGGCCGCGAAGCT
CGCCGAGCGCGGCCTGCATTACGTGGACGTCGGCACCTCCGGCGGCGTGTTCGGGCTGGAGCGCGGCTACTGCCTGATGA
TCGGCGGCGAGCCGGAGGTGGCCGCCCGCCTCGAGCCGCTGTTCGAGACGATCGCGCCCGGCGTCGACACCGCGCCGCGG
ACCCCGGGCCGGACGGGCGAGATCGCCCAGGCCGAGAAGGGCTACCTGTACTGCGGCCCGAACGGGGCAGGCCACTTCGT
CAAGATGATCCACAACGGGATCGAGTACGGCATGATGGCTGCCTTCGCCGAGGGCATGGGCATCCTGGAGAAGGCCGGCA
TCGGGCGTTCCGAGGCCGCCCTGCACGACGCCGAGACGGCGCCGCTGGCCCATCCGGAGTACTACCAGTACGACTTCGAC
ATCGCCTCCGTCGCCGAGGTGTGGCGGCGCGGCAGCGTGGTCAGCTCCTGGCTGCTGGACCTGACCGCCACCGCGCTCGC
CGAGGACCCGCGGCTCTCCGAGTTCGGCGGGCGTGTCTCCGACTCCGGCGAGGGCCGGTGGACGGTGCTGGCCGCCGTCG
AGGAGGGCGTCCCGGCCCACGTGCTGACCGCGTCGCTCTACGAGCGGTTCAGCTCCCGCGGCGAGTCGCTGTTCGCCGAC
AAGCTGCTGTCGGCGATGCGCAAGCAGTTCGGCGGCCACGCCGAGAAGAAGGCGGAGGGCTAG

Upstream 100 bases:

>100_bases
CCGTGACCGAGGACGCCCCGAGGTGTCCCGGTGCCGACGGCAGGATGGAGCTCGAGGACCTCACCTTCGACCGGTCCGTG
CAGGACCATCGGGAGTTCAG

Downstream 100 bases:

>100_bases
CGTGGCGGGTGAGTGGGTCTAACAGACCCACTCACCCGCCACATATCTCCCAGCCGGCCCGGCAAGGGGCTGGTTTGGCT
TCGGGACCCCGAACTTCGGG

Product: 6-phosphogluconate dehydrogenase-like protein

Products: D-ribulose 5-phosphate; CO2; NADPH

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MQLGMIGLGRMGANLVRRLMRDGHECVVYDVNPETVKSLAAEGAVGVNSLADFAAALSTPRAAWVMVPAGLTGQTVFELA
EHFEAGDIIIDGGNSYYRDDVDRAAKLAERGLHYVDVGTSGGVFGLERGYCLMIGGEPEVAARLEPLFETIAPGVDTAPR
TPGRTGEIAQAEKGYLYCGPNGAGHFVKMIHNGIEYGMMAAFAEGMGILEKAGIGRSEAALHDAETAPLAHPEYYQYDFD
IASVAEVWRRGSVVSSWLLDLTATALAEDPRLSEFGGRVSDSGEGRWTVLAAVEEGVPAHVLTASLYERFSSRGESLFAD
KLLSAMRKQFGGHAEKKAEG

Sequences:

>Translated_340_residues
MQLGMIGLGRMGANLVRRLMRDGHECVVYDVNPETVKSLAAEGAVGVNSLADFAAALSTPRAAWVMVPAGLTGQTVFELA
EHFEAGDIIIDGGNSYYRDDVDRAAKLAERGLHYVDVGTSGGVFGLERGYCLMIGGEPEVAARLEPLFETIAPGVDTAPR
TPGRTGEIAQAEKGYLYCGPNGAGHFVKMIHNGIEYGMMAAFAEGMGILEKAGIGRSEAALHDAETAPLAHPEYYQYDFD
IASVAEVWRRGSVVSSWLLDLTATALAEDPRLSEFGGRVSDSGEGRWTVLAAVEEGVPAHVLTASLYERFSSRGESLFAD
KLLSAMRKQFGGHAEKKAEG
>Mature_340_residues
MQLGMIGLGRMGANLVRRLMRDGHECVVYDVNPETVKSLAAEGAVGVNSLADFAAALSTPRAAWVMVPAGLTGQTVFELA
EHFEAGDIIIDGGNSYYRDDVDRAAKLAERGLHYVDVGTSGGVFGLERGYCLMIGGEPEVAARLEPLFETIAPGVDTAPR
TPGRTGEIAQAEKGYLYCGPNGAGHFVKMIHNGIEYGMMAAFAEGMGILEKAGIGRSEAALHDAETAPLAHPEYYQYDFD
IASVAEVWRRGSVVSSWLLDLTATALAEDPRLSEFGGRVSDSGEGRWTVLAAVEEGVPAHVLTASLYERFSSRGESLFAD
KLLSAMRKQFGGHAEKKAEG

Specific function: May act as NAD-dependent 6-P-gluconate dehydrogenase [H]

COG id: COG1023

COG function: function code G; Predicted 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=345, Percent_Identity=31.0144927536232, Blast_Score=120, Evalue=1e-27,
Organism=Escherichia coli, GI1788341, Length=347, Percent_Identity=29.3948126801153, Blast_Score=141, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17542558, Length=338, Percent_Identity=30.1775147928994, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321695, Length=335, Percent_Identity=31.044776119403, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6321977, Length=334, Percent_Identity=29.940119760479, Blast_Score=125, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24639279, Length=320, Percent_Identity=30, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR004849
- InterPro:   IPR006114
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: 1.1.1.44

Molecular weight: Translated: 36290; Mature: 36290

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLGMIGLGRMGANLVRRLMRDGHECVVYDVNPETVKSLAAEGAVGVNSLADFAAALSTP
CCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHCCC
RAAWVMVPAGLTGQTVFELAEHFEAGDIIIDGGNSYYRDDVDRAAKLAERGLHYVDVGTS
CEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCC
GGVFGLERGYCLMIGGEPEVAARLEPLFETIAPGVDTAPRTPGRTGEIAQAEKGYLYCGP
CCEEEECCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECC
NGAGHFVKMIHNGIEYGMMAAFAEGMGILEKAGIGRSEAALHDAETAPLAHPEYYQYDFD
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEECCC
IASVAEVWRRGSVVSSWLLDLTATALAEDPRLSEFGGRVSDSGEGRWTVLAAVEEGVPAH
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEEEECCCCCHH
VLTASLYERFSSRGESLFADKLLSAMRKQFGGHAEKKAEG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MQLGMIGLGRMGANLVRRLMRDGHECVVYDVNPETVKSLAAEGAVGVNSLADFAAALSTP
CCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHCCC
RAAWVMVPAGLTGQTVFELAEHFEAGDIIIDGGNSYYRDDVDRAAKLAERGLHYVDVGTS
CEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCC
GGVFGLERGYCLMIGGEPEVAARLEPLFETIAPGVDTAPRTPGRTGEIAQAEKGYLYCGP
CCEEEECCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECC
NGAGHFVKMIHNGIEYGMMAAFAEGMGILEKAGIGRSEAALHDAETAPLAHPEYYQYDFD
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEECCC
IASVAEVWRRGSVVSSWLLDLTATALAEDPRLSEFGGRVSDSGEGRWTVLAAVEEGVPAH
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEEEECCCCCHH
VLTASLYERFSSRGESLFADKLLSAMRKQFGGHAEKKAEG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.05 {6-phosphogluconate}} 0.01 {6-phosphogluconate}} [C]

Substrates: 6-phospho-D-gluconate; NADP+

Specific reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]