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The map label for this gene is acdA [H]

Identifier: 158317337

GI number: 158317337

Start: 6772831

End: 6774045

Strand: Direct

Name: acdA [H]

Synonym: Franean1_5587

Alternate gene names: 158317337

Gene position: 6772831-6774045 (Clockwise)

Preceding gene: 158317332

Following gene: 158317339

Centisome position: 75.4

GC content: 71.19

Gene sequence:

>1215_bases
ATGAGCGGCTTCAGCCTCGACCTCACCGACGAGCAGACTGAGCTGCGGCGGTGGGTGCACGGCTTCGCCGCGGACGTCGT
CCGCCAGGCGGCGGCCGAGTGGGACGAGCGGGAGGAGACTCCCTGGCCGGTGATCCAGGAGGCCGCCAAGATCGGCCTCT
ACAACTTCGACACGCTGGCCACGCTGTGGGCCGAGGAGACCGGCCTGGGCCTGCCGCTCCTCTCCGAGGAGCTGTTCTGG
GGCGACGCGGGCATCGGCATGTCGATCATGGGAACGTCGCTGGCGGTTGCCGGGATCGCGTCGGCCGGCACGTTCGACCA
GCTCGGCGAATGGGTGCCCCAGTGCTTCGGTGACGCCGCCGACCCGAAGGTGGCCGCGTACTGCGTGTCCGAGCCCGAGG
CCGGCTCGGACGTCTCGTCGATGCGGGTCCGCGCCCGCTACGACGAGGCGACCGACGAATGGGTGATCAACGGCCAGAAA
GCGTGGATCACGAACGGCGGCATCGCGAACGTCCACGTGGTCGTCGCCTCGGTCGACCCGACGCTGCGCGGCCGCGGCCA
GGCCGCGTTCGTCGTCCCGCCCGGCACCCCCGGGCTGACCGGGAACAGGAAGATCAAGAAACTCGGCCTGCGGGCCTCGC
ACACCGCCGACGTCTTTCTCGACGACGTCCGGGTGCCCGGCCGGTGCCTGCTCGGCGGCAAGGAGAAACTGGATGAGCGG
CTCGCCCGTGCCCGCGAGGGCTCCCGCTCCGCCGGCCAGGCCGCCCTGCAGACCTTCGAGATGACCCGCCCCACGGTCGG
CGCGCAGGCGGTGGGCATCGCCCGGGCCGCCTACGAGTACGCGCTGGACTACGCCCGCCACCGGGAGCAGTTCGGACGTC
CGATCATCACCAACCAGGCCGTCGCGTTCGCGCTGGCCGACATGCGGATGGAGATCGACGCGGCCCGCTTGCTCATCTGG
CGCGCCGCGTGGATGGGCCGCAACGAGCGGCGCTTCGAGGCCGGGGAGGGCTCGATGTCGAAGCTCAAGGCCGGCGAGGT
CGCGGTGTGGGCGACCGAGAAGGCGGTGCAGATCCTCGGCGGCGCCGGCTACAGCCGCGAGCACCCGGTGGAGCGCATGT
ACCGCGACGCCAAGATCTACACCATCTTCGAGGGGACCTCGGAGATCCAGCGGCTCGTGGTCGCGCGGGCCATCTCCGGA
ATGCGCCTCTCCTGA

Upstream 100 bases:

>100_bases
CACCGCCCGACGCGGCGGCCGACGGATCGTCAAGGGAGAATGTAGGACCCATCGGCGCGACACGTACCGGTCCGGACGGC
CGGGGCAACGAGAGGAATCC

Downstream 100 bases:

>100_bases
TCCGCGGATGGCGGCGGTCGGAGCCGCACGGCGCCCGGATTTACCGGATTGAGTCGCGGAATCCCGGCAACATACGGGGT
CTGCCGACGTGAAGCAGTCT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSGFSLDLTDEQTELRRWVHGFAADVVRQAAAEWDEREETPWPVIQEAAKIGLYNFDTLATLWAEETGLGLPLLSEELFW
GDAGIGMSIMGTSLAVAGIASAGTFDQLGEWVPQCFGDAADPKVAAYCVSEPEAGSDVSSMRVRARYDEATDEWVINGQK
AWITNGGIANVHVVVASVDPTLRGRGQAAFVVPPGTPGLTGNRKIKKLGLRASHTADVFLDDVRVPGRCLLGGKEKLDER
LARAREGSRSAGQAALQTFEMTRPTVGAQAVGIARAAYEYALDYARHREQFGRPIITNQAVAFALADMRMEIDAARLLIW
RAAWMGRNERRFEAGEGSMSKLKAGEVAVWATEKAVQILGGAGYSREHPVERMYRDAKIYTIFEGTSEIQRLVVARAISG
MRLS

Sequences:

>Translated_404_residues
MSGFSLDLTDEQTELRRWVHGFAADVVRQAAAEWDEREETPWPVIQEAAKIGLYNFDTLATLWAEETGLGLPLLSEELFW
GDAGIGMSIMGTSLAVAGIASAGTFDQLGEWVPQCFGDAADPKVAAYCVSEPEAGSDVSSMRVRARYDEATDEWVINGQK
AWITNGGIANVHVVVASVDPTLRGRGQAAFVVPPGTPGLTGNRKIKKLGLRASHTADVFLDDVRVPGRCLLGGKEKLDER
LARAREGSRSAGQAALQTFEMTRPTVGAQAVGIARAAYEYALDYARHREQFGRPIITNQAVAFALADMRMEIDAARLLIW
RAAWMGRNERRFEAGEGSMSKLKAGEVAVWATEKAVQILGGAGYSREHPVERMYRDAKIYTIFEGTSEIQRLVVARAISG
MRLS
>Mature_403_residues
SGFSLDLTDEQTELRRWVHGFAADVVRQAAAEWDEREETPWPVIQEAAKIGLYNFDTLATLWAEETGLGLPLLSEELFWG
DAGIGMSIMGTSLAVAGIASAGTFDQLGEWVPQCFGDAADPKVAAYCVSEPEAGSDVSSMRVRARYDEATDEWVINGQKA
WITNGGIANVHVVVASVDPTLRGRGQAAFVVPPGTPGLTGNRKIKKLGLRASHTADVFLDDVRVPGRCLLGGKEKLDERL
ARAREGSRSAGQAALQTFEMTRPTVGAQAVGIARAAYEYALDYARHREQFGRPIITNQAVAFALADMRMEIDAARLLIWR
AAWMGRNERRFEAGEGSMSKLKAGEVAVWATEKAVQILGGAGYSREHPVERMYRDAKIYTIFEGTSEIQRLVVARAISGM
RLS

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=403, Percent_Identity=39.2059553349876, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI187960098, Length=403, Percent_Identity=39.2059553349876, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI4557233, Length=398, Percent_Identity=38.1909547738693, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI4501859, Length=402, Percent_Identity=32.8358208955224, Blast_Score=191, Evalue=7e-49,
Organism=Homo sapiens, GI7656849, Length=403, Percent_Identity=28.7841191066998, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI76496475, Length=405, Percent_Identity=32.5925925925926, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI4557235, Length=405, Percent_Identity=32.5925925925926, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI226958412, Length=404, Percent_Identity=28.4653465346535, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI4501857, Length=400, Percent_Identity=27, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI226958414, Length=331, Percent_Identity=29.9093655589124, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI21361497, Length=403, Percent_Identity=28.287841191067, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4503943, Length=364, Percent_Identity=29.3956043956044, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI7669494, Length=346, Percent_Identity=28.6127167630058, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI48976061, Length=332, Percent_Identity=26.8072289156627, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI211971008, Length=332, Percent_Identity=26.8072289156627, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI38505218, Length=303, Percent_Identity=24.4224422442244, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87081958, Length=283, Percent_Identity=31.095406360424, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786223, Length=270, Percent_Identity=28.5185185185185, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082384, Length=286, Percent_Identity=26.2237762237762, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17569725, Length=402, Percent_Identity=38.5572139303483, Blast_Score=254, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI17534899, Length=404, Percent_Identity=37.3762376237624, Blast_Score=248, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI17570075, Length=408, Percent_Identity=37.0098039215686, Blast_Score=235, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17506239, Length=398, Percent_Identity=32.4120603015075, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17508101, Length=393, Percent_Identity=32.3155216284987, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17538396, Length=413, Percent_Identity=31.4769975786925, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71985184, Length=405, Percent_Identity=28.3950617283951, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17533517, Length=386, Percent_Identity=25.3886010362694, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17534353, Length=404, Percent_Identity=27.2277227722772, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71990804, Length=273, Percent_Identity=32.6007326007326, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17505929, Length=323, Percent_Identity=31.2693498452012, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17551932, Length=330, Percent_Identity=30.3030303030303, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=32.6086956521739, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71985192, Length=351, Percent_Identity=27.0655270655271, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17531909, Length=247, Percent_Identity=29.1497975708502, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71982178, Length=291, Percent_Identity=26.1168384879725, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17531913, Length=193, Percent_Identity=29.5336787564767, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24660351, Length=402, Percent_Identity=39.3034825870647, Blast_Score=255, Evalue=4e-68,
Organism=Drosophila melanogaster, GI21356377, Length=400, Percent_Identity=34.5, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24646207, Length=397, Percent_Identity=34.0050377833753, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24666513, Length=401, Percent_Identity=29.6758104738155, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI281363737, Length=324, Percent_Identity=32.7160493827161, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI21355753, Length=400, Percent_Identity=29.75, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI19920834, Length=407, Percent_Identity=26.2899262899263, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44066; Mature: 43935

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGFSLDLTDEQTELRRWVHGFAADVVRQAAAEWDEREETPWPVIQEAAKIGLYNFDTLA
CCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHH
TLWAEETGLGLPLLSEELFWGDAGIGMSIMGTSLAVAGIASAGTFDQLGEWVPQCFGDAA
HHHHHHCCCCCCHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
DPKVAAYCVSEPEAGSDVSSMRVRARYDEATDEWVINGQKAWITNGGIANVHVVVASVDP
CCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCEEECCCEEEEECCCCEEEEEEEEECCC
TLRGRGQAAFVVPPGTPGLTGNRKIKKLGLRASHTADVFLDDVRVPGRCLLGGKEKLDER
CCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCCCHHHEEECCCCCCEEEECCHHHHHHH
LARAREGSRSAGQAALQTFEMTRPTVGAQAVGIARAAYEYALDYARHREQFGRPIITNQA
HHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
VAFALADMRMEIDAARLLIWRAAWMGRNERRFEAGEGSMSKLKAGEVAVWATEKAVQILG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHCCCCEEEEEHHHHHHHHC
GAGYSREHPVERMYRDAKIYTIFEGTSEIQRLVVARAISGMRLS
CCCCCCCCCHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SGFSLDLTDEQTELRRWVHGFAADVVRQAAAEWDEREETPWPVIQEAAKIGLYNFDTLA
CCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHH
TLWAEETGLGLPLLSEELFWGDAGIGMSIMGTSLAVAGIASAGTFDQLGEWVPQCFGDAA
HHHHHHCCCCCCHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
DPKVAAYCVSEPEAGSDVSSMRVRARYDEATDEWVINGQKAWITNGGIANVHVVVASVDP
CCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCEEECCCEEEEECCCCEEEEEEEEECCC
TLRGRGQAAFVVPPGTPGLTGNRKIKKLGLRASHTADVFLDDVRVPGRCLLGGKEKLDER
CCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCCCHHHEEECCCCCCEEEECCHHHHHHH
LARAREGSRSAGQAALQTFEMTRPTVGAQAVGIARAAYEYALDYARHREQFGRPIITNQA
HHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
VAFALADMRMEIDAARLLIWRAAWMGRNERRFEAGEGSMSKLKAGEVAVWATEKAVQILG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHCCCCEEEEEHHHHHHHHC
GAGYSREHPVERMYRDAKIYTIFEGTSEIQRLVVARAISGMRLS
CCCCCCCCCHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]