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The map label for this gene is cmcT [H]

Identifier: 158317130

GI number: 158317130

Start: 6478539

End: 6479984

Strand: Reverse

Name: cmcT [H]

Synonym: Franean1_5374

Alternate gene names: 158317130

Gene position: 6479984-6478539 (Counterclockwise)

Preceding gene: 158317131

Following gene: 158317129

Centisome position: 72.14

GC content: 70.75

Gene sequence:

>1446_bases
TTGAAAAAATCTGCCCGTAGCGCCCTGACGCTGCTCGCCGGCACCCAGTTCCTCCTTATTCTGGACACGGCGATCATAAA
TGTCGCGGCGCCGTCGATCGGGGACGAGTTCGACGTCTCGGCGGCGACTCTGTCCTGGGTGGCCAACGCCTATCTGGTGA
CGTTCGGCGGGCTGTTGCTGCTCAGTGGTCGTCTGGCGGACCTGTTCGGGCGCAGGCGGCTGTTCCTCACAGGTCTGGCC
GTCCTGGTCGCCGCGTCGCTGACCGGCGCGGTGGCGCAGACGGCCTCGTGGCTGATCGCCGCCCGTGCGGTGCAGGGTGC
CGGTGCGGCTCTGGCGGCGGCCGCGGCGTTCGCCCTGCTGCTCAGCCTGTTCCCAGACGGCCCCGACCGTCATCGGGCGC
TGGGCGTGTTCGCGGCGATGGCCGGCGCGGGCGGCGCCGCGGGAACCGTGCTCGGCGGCGTGCTCACGAGCTGGTTGACC
TGGCGGTCCACGTTCGGGTTGAACGTGGTCGCCGGCCTCGTGCTCGTCGGGTCGGCCCTTCGGGCGCTGGCGCCGGACAC
GCGTCCGTCGGCACGCCTCGGCTTCGACCTCGGTGGCGCGCTGTCCGTCACCTCGGGGCTCGCGCTGCTCGCCTACAGCC
TGGTGAACACGGGGGTGGCCGGCTGGATCTCGCCGCGGACCCTCGTACCCGGCGCGACGGCGGTGGTTCTCCTGGCGGTC
TTCGTCTGGCTGGAGGGCAGGGTGCGCGTTCCCCTGGTTCCGGCCGCGGTCGTGCGCAGGCCGGTCCTACGCCGGGCGAA
CCTCCTCTCTGCGCTCGGGCAGGTCGTGCTCTTTCCGATGTTCTTCCTCGTCAGTGTGTATCTGCAGGATGTTCTCGGTT
ACTCACCGGTCGCGGGCGGCAGCGCGCTGCTCCCGTTGTGCGTCGTGGTCATTCTGGTGGCTTCCAACGCGGACCGGCTG
ATCGGCGGCCTCGGGCTCCGGCCGGCGATGACCGCGGGCTATGTGCTCGTGGCCGTCGGCATGGCGTGGCTGTCGCTGCT
GTCTCCCGATGGCTCGTTCACCGGGGACATCCTCCTGCCCAGCCTGATCCTCGGGGTCGGCCTTCCGCTGGTTGCCATCA
CCACGAACGTCGCGGCGACCGCGGACGCCGGGCCGGAGGAGATCGGCCTCGCCTCCGGGCTGATCAACACCAGCCAGCAG
TTCGGCTCGGTCATCGGTCTGGCCGTGCTGAGCGGTATCGCCAGCGCGCGCGTCTCCGCCGAGGGCGGTCCGGACGATCC
CGCGGCGCTCACCAGTGGATTCGCCGTCGCGTTCATCGTCGCCTCCGCCATCGCGCTGCTGTCCGCCCTCTACGCGGCGG
TGCCACGGACGGCGAGACCACAGCAGGAGCCGACCTGGGAAAGGCCACCGGTGTCGATGGCCGCACCAGGCGACAGGGAG
AGCTGA

Upstream 100 bases:

>100_bases
CGTCCGGAACTTCTTGAGCAGCTCGTCGAGAGGTGCATGCAGGGCTATGACCTTCCCGCCGAGCCGGCGCTGACGAGCTA
GCCGAAACAGGTGATACCTT

Downstream 100 bases:

>100_bases
GCCCCCTGGGGGCGCATCACGACACAGCGACCGGTGCGTCCGCGGCCGCCGCCGGCCCACGACAGCACAGCGACGAAAGG
GCGAGAAACCATGTCAGAGA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MKKSARSALTLLAGTQFLLILDTAIINVAAPSIGDEFDVSAATLSWVANAYLVTFGGLLLLSGRLADLFGRRRLFLTGLA
VLVAASLTGAVAQTASWLIAARAVQGAGAALAAAAAFALLLSLFPDGPDRHRALGVFAAMAGAGGAAGTVLGGVLTSWLT
WRSTFGLNVVAGLVLVGSALRALAPDTRPSARLGFDLGGALSVTSGLALLAYSLVNTGVAGWISPRTLVPGATAVVLLAV
FVWLEGRVRVPLVPAAVVRRPVLRRANLLSALGQVVLFPMFFLVSVYLQDVLGYSPVAGGSALLPLCVVVILVASNADRL
IGGLGLRPAMTAGYVLVAVGMAWLSLLSPDGSFTGDILLPSLILGVGLPLVAITTNVAATADAGPEEIGLASGLINTSQQ
FGSVIGLAVLSGIASARVSAEGGPDDPAALTSGFAVAFIVASAIALLSALYAAVPRTARPQQEPTWERPPVSMAAPGDRE
S

Sequences:

>Translated_481_residues
MKKSARSALTLLAGTQFLLILDTAIINVAAPSIGDEFDVSAATLSWVANAYLVTFGGLLLLSGRLADLFGRRRLFLTGLA
VLVAASLTGAVAQTASWLIAARAVQGAGAALAAAAAFALLLSLFPDGPDRHRALGVFAAMAGAGGAAGTVLGGVLTSWLT
WRSTFGLNVVAGLVLVGSALRALAPDTRPSARLGFDLGGALSVTSGLALLAYSLVNTGVAGWISPRTLVPGATAVVLLAV
FVWLEGRVRVPLVPAAVVRRPVLRRANLLSALGQVVLFPMFFLVSVYLQDVLGYSPVAGGSALLPLCVVVILVASNADRL
IGGLGLRPAMTAGYVLVAVGMAWLSLLSPDGSFTGDILLPSLILGVGLPLVAITTNVAATADAGPEEIGLASGLINTSQQ
FGSVIGLAVLSGIASARVSAEGGPDDPAALTSGFAVAFIVASAIALLSALYAAVPRTARPQQEPTWERPPVSMAAPGDRE
S
>Mature_481_residues
MKKSARSALTLLAGTQFLLILDTAIINVAAPSIGDEFDVSAATLSWVANAYLVTFGGLLLLSGRLADLFGRRRLFLTGLA
VLVAASLTGAVAQTASWLIAARAVQGAGAALAAAAAFALLLSLFPDGPDRHRALGVFAAMAGAGGAAGTVLGGVLTSWLT
WRSTFGLNVVAGLVLVGSALRALAPDTRPSARLGFDLGGALSVTSGLALLAYSLVNTGVAGWISPRTLVPGATAVVLLAV
FVWLEGRVRVPLVPAAVVRRPVLRRANLLSALGQVVLFPMFFLVSVYLQDVLGYSPVAGGSALLPLCVVVILVASNADRL
IGGLGLRPAMTAGYVLVAVGMAWLSLLSPDGSFTGDILLPSLILGVGLPLVAITTNVAATADAGPEEIGLASGLINTSQQ
FGSVIGLAVLSGIASARVSAEGGPDDPAALTSGFAVAFIVASAIALLSALYAAVPRTARPQQEPTWERPPVSMAAPGDRE
S

Specific function: Involved in cephamycin export [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=404, Percent_Identity=30.1980198019802, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1790195, Length=494, Percent_Identity=26.9230769230769, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1789042, Length=421, Percent_Identity=23.7529691211401, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1788710, Length=372, Percent_Identity=25, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788392, Length=474, Percent_Identity=25.1054852320675, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324954, Length=411, Percent_Identity=25.3041362530414, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323520, Length=246, Percent_Identity=26.0162601626016, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48682; Mature: 48682

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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C
>Mature Secondary Structure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C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8440253 [H]