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The map label for this gene is trpE [H]

Identifier: 158316915

GI number: 158316915

Start: 6182617

End: 6183813

Strand: Reverse

Name: trpE [H]

Synonym: Franean1_5159

Alternate gene names: 158316915

Gene position: 6183813-6182617 (Counterclockwise)

Preceding gene: 158316916

Following gene: 158316912

Centisome position: 68.85

GC content: 74.69

Gene sequence:

>1197_bases
ATGACTGGGGCGAATGGGGGCACAACGCACGGGGGCTCGACGGACAGGAGCGGCACGAAGGTGCGTCTACGAGCGACCGG
CGGGCCCGTCGCGGCGCGGGTTCGCGGCCGGGAGTCCTATCTGCTGGCGGGCGGCAGGCTCGCCACCGGGGTCGTGGAGG
TGCACGACGACCTCCGGGTGCTCGACCGCGGTGGCTTCTGGGGAGTCGTCGTCGACTTCGAGGGTCGTACCCGCTGCGTC
CGGTTCAGGCACGTGCGCCCGGCGCCTGACGTCACGGCGCTCGCGGCCGGGCCGTGGCGCGGCCCCGCCCGGACGGACTG
GGCGACGAGCATGGACGCCGCGGCCTACATCGCCGGCGTCCACGCGATCCGGTCCGAGATCGCCGCCGGCGAGGTCTACC
AGGTGAACCTGTGCCGGCTGCTGTCCGCGCCTACCGTCCCCGGCCCCGCCGGCACGGACCTCGCCGCGCTGGCGACCGTC
CTGGCCGCGGGCAACCCGGCCCCCTACTCGGTGGTGCTCGACGCCCCCGAGGCCGGCGTACGCATCGTCGGGGCCTCACC
GGAGCTGTTCCTGTCGCGGGAGGGCGACCTCGTACGGTCCGGCCCGATCAAGGGCACCGGGCGCACGGTCGCCGACCTGC
GGGACAAGGACGTCGCGGAGAACGTCATGATCGTCGACCTTGTTCGCAACGACCTGGGACGGGTCGCCCGGCCCGGCAGC
GTCACGGTGCCCGCGCTGTGCGCGGTGGAACGGCATCCCGGCCTGGTTCACCTCGTGTCGACCGTGCAGGCCACGCTCGC
GCCGGGCGTGGGGTGGGCCGAGCTGCTGGCCGCGACCTGCCCACCCGGCTCGGTGTCGGGAGCGCCCAAGTCGAGCGCGC
TGCGGATCATCCGGGAGCTGGAGCCGGTGGCGCGCGGCCACTACTGCGGCGGCATCGGCTGGGTGGACGCCGACAGCGGA
CGTGGCTGGCTGTCGGTGGGAATCCGCACGTTCTGGCTCGCCGACGAGCGGATCTGGTTCGGGACAGGCGCCGGCATCAC
CTGGGGCAGCGACCCGGAGGCCGAATGGCGCGAGACCGAGCTGAAGGCGCACCGGCTGCTTGCCCTGGCCTCGTCACCAG
GGCGGGACGGCCGGACCGGTCCCTCCATGCCGCCACGCGAGGCGGCCCGGACCCGGCGGATCGCGGCGGCCCGCTGA

Upstream 100 bases:

>100_bases
GTACACAGGGGCACAGGGCAAAACCTCCGCCGTCTCCGGGCGCCACGCGCACGGTGACCTGGGCGTGGGGTACGGCGACC
ACGGCGATACGGTGATCAGG

Downstream 100 bases:

>100_bases
CCGCGGACAGCGAAACGCCTGGTGGGGAAGTGCTCCCCACCAGGCGAATGATCGTGCGCCTGATCTGTGCCGGAAGTGCC
CGCACCGGTTTGCCGGGGTC

Product: anthranilate synthase component I/chorismate-binding protein

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTGANGGTTHGGSTDRSGTKVRLRATGGPVAARVRGRESYLLAGGRLATGVVEVHDDLRVLDRGGFWGVVVDFEGRTRCV
RFRHVRPAPDVTALAAGPWRGPARTDWATSMDAAAYIAGVHAIRSEIAAGEVYQVNLCRLLSAPTVPGPAGTDLAALATV
LAAGNPAPYSVVLDAPEAGVRIVGASPELFLSREGDLVRSGPIKGTGRTVADLRDKDVAENVMIVDLVRNDLGRVARPGS
VTVPALCAVERHPGLVHLVSTVQATLAPGVGWAELLAATCPPGSVSGAPKSSALRIIRELEPVARGHYCGGIGWVDADSG
RGWLSVGIRTFWLADERIWFGTGAGITWGSDPEAEWRETELKAHRLLALASSPGRDGRTGPSMPPREAARTRRIAAAR

Sequences:

>Translated_398_residues
MTGANGGTTHGGSTDRSGTKVRLRATGGPVAARVRGRESYLLAGGRLATGVVEVHDDLRVLDRGGFWGVVVDFEGRTRCV
RFRHVRPAPDVTALAAGPWRGPARTDWATSMDAAAYIAGVHAIRSEIAAGEVYQVNLCRLLSAPTVPGPAGTDLAALATV
LAAGNPAPYSVVLDAPEAGVRIVGASPELFLSREGDLVRSGPIKGTGRTVADLRDKDVAENVMIVDLVRNDLGRVARPGS
VTVPALCAVERHPGLVHLVSTVQATLAPGVGWAELLAATCPPGSVSGAPKSSALRIIRELEPVARGHYCGGIGWVDADSG
RGWLSVGIRTFWLADERIWFGTGAGITWGSDPEAEWRETELKAHRLLALASSPGRDGRTGPSMPPREAARTRRIAAAR
>Mature_397_residues
TGANGGTTHGGSTDRSGTKVRLRATGGPVAARVRGRESYLLAGGRLATGVVEVHDDLRVLDRGGFWGVVVDFEGRTRCVR
FRHVRPAPDVTALAAGPWRGPARTDWATSMDAAAYIAGVHAIRSEIAAGEVYQVNLCRLLSAPTVPGPAGTDLAALATVL
AAGNPAPYSVVLDAPEAGVRIVGASPELFLSREGDLVRSGPIKGTGRTVADLRDKDVAENVMIVDLVRNDLGRVARPGSV
TVPALCAVERHPGLVHLVSTVQATLAPGVGWAELLAATCPPGSVSGAPKSSALRIIRELEPVARGHYCGGIGWVDADSGR
GWLSVGIRTFWLADERIWFGTGAGITWGSDPEAEWRETELKAHRLLALASSPGRDGRTGPSMPPREAARTRRIAAAR

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=275, Percent_Identity=37.4545454545455, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1787518, Length=268, Percent_Identity=32.8358208955224, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1786809, Length=252, Percent_Identity=29.7619047619048, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320935, Length=277, Percent_Identity=31.7689530685921, Blast_Score=112, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6324361, Length=310, Percent_Identity=24.5161290322581, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 41730; Mature: 41599

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGANGGTTHGGSTDRSGTKVRLRATGGPVAARVRGRESYLLAGGRLATGVVEVHDDLRV
CCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCEEEEECCCCEECEEEECCCEEE
LDRGGFWGVVVDFEGRTRCVRFRHVRPAPDVTALAAGPWRGPARTDWATSMDAAAYIAGV
EECCCEEEEEEEECCCEEEEEEEECCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHH
HAIRSEIAAGEVYQVNLCRLLSAPTVPGPAGTDLAALATVLAAGNPAPYSVVLDAPEAGV
HHHHHHHHCCCEEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCE
RIVGASPELFLSREGDLVRSGPIKGTGRTVADLRDKDVAENVMIVDLVRNDLGRVARPGS
EEEECCCCEEEECCCCEEECCCCCCCCCCHHHHCCCHHHCCEEEEEHHHHHHHHCCCCCC
VTVPALCAVERHPGLVHLVSTVQATLAPGVGWAELLAATCPPGSVSGAPKSSALRIIREL
CCCHHEEEECCCCCEEEHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
EPVARGHYCGGIGWVDADSGRGWLSVGIRTFWLADERIWFGTGAGITWGSDPEAEWRETE
HHHHCCCCCCCEEEEECCCCCCEEEECEEEEEEECCEEEEECCCCCCCCCCCCCHHHHHH
LKAHRLLALASSPGRDGRTGPSMPPREAARTRRIAAAR
HHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TGANGGTTHGGSTDRSGTKVRLRATGGPVAARVRGRESYLLAGGRLATGVVEVHDDLRV
CCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCEEEEECCCCEECEEEECCCEEE
LDRGGFWGVVVDFEGRTRCVRFRHVRPAPDVTALAAGPWRGPARTDWATSMDAAAYIAGV
EECCCEEEEEEEECCCEEEEEEEECCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHH
HAIRSEIAAGEVYQVNLCRLLSAPTVPGPAGTDLAALATVLAAGNPAPYSVVLDAPEAGV
HHHHHHHHCCCEEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCE
RIVGASPELFLSREGDLVRSGPIKGTGRTVADLRDKDVAENVMIVDLVRNDLGRVARPGS
EEEECCCCEEEECCCCEEECCCCCCCCCCHHHHCCCHHHCCEEEEEHHHHHHHHCCCCCC
VTVPALCAVERHPGLVHLVSTVQATLAPGVGWAELLAATCPPGSVSGAPKSSALRIIREL
CCCHHEEEECCCCCEEEHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
EPVARGHYCGGIGWVDADSGRGWLSVGIRTFWLADERIWFGTGAGITWGSDPEAEWRETE
HHHHCCCCCCCEEEEECCCCCCEEEECEEEEEEECCEEEEECCCCCCCCCCCCCHHHHHH
LKAHRLLALASSPGRDGRTGPSMPPREAARTRRIAAAR
HHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]