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The map label for this gene is ftsI [H]

Identifier: 158316861

GI number: 158316861

Start: 6110573

End: 6113092

Strand: Reverse

Name: ftsI [H]

Synonym: Franean1_5104

Alternate gene names: 158316861

Gene position: 6113092-6110573 (Counterclockwise)

Preceding gene: 158316862

Following gene: 158316860

Centisome position: 68.06

GC content: 74.84

Gene sequence:

>2520_bases
GTGAGCCAGACGACCCGCGGTCCGTCCTCCGGCCGCGGTCGGAACCGACTCCGTCTCGTCACGAACCCGCACCCGGGGAG
CCCGGACTCGCGGTCCGCGCGCCACGACGGTGACGACCTGCTCGATCCGTCCGTGCGCCGGTTCTCCGGCCGTGACCCGG
ACGGCGGCCGCGGCCGGATGACCCCGCCCCCCCGCGGCGGCGACCGACACGGTGACGACCGGCGCGGCTACGACGCTGCC
CGGCCTCGAAACGACCGGCGCCAGGACGCCCGCCGCCGCGACGACCGCGACGACCGCGACGACCGCGACGACCGCGACGA
CCGCGACGACCGCGACGACCGCGACGACCGCGACGACCGCGACGAGCTTGACGAACAGACCTGGGACGACGCCGCCGCCG
AAGCCACGGAACGGGCGGCGCGCCGTCCCCGGCCCCGCCCCGCCGCGGCCGGACGGGAGCGCCGGGCGGCGACGGCCCGG
GCGGGTCGGTCGTCCCCACGGGTGTCTCCGCTGCGCAGCGCGGCCGCCGGCTCGGCGACGCCACGTGAGCAGCTCCGCCG
GGACCAGGCCGCCCGCGCCACATCCGCCCGTACGACCTCCGCCCGCGGGGCGGCCGGCCGGCGTAACCCGACCCGGGGGG
CGGCCAGCCGGACGACGTCCGGGCGGATCCCCCCCGTCCGGCGCCCGCATCCCTCGAGCGGTGGGGCGGGCCGCAACCGG
GCCACCTCGATCCGGCGCGGCCTCGGGGGCGCGCCGCCGCGGCCGCCGCGGCCGTTCGTCCTCGCCAGCCCCCGCCGCCG
GGTCCGGGTGTCGGTGGTACTGATGATCGCCGTCCTGGTCGTGATCGCCGGCCGGCTCGCGCAGCTGCAGGGCTTCGCCT
CGTCCAACTACGCGGAGCAGGCCGAGCAGCAGCGGCTGCGCAAGTCCGTCCTGCCCGCCGACCGCGGCATGATCACCGAC
CGGCACGGCGACGCGCTGGCGCAGGACGTCGAGCGCCGGGCCGTGTACGCGGACCCGTGGCTGATGAACGAGGCCCAGGT
CGTCGACGCGGCGCGCAAGCTGGCCCCGCTGCTCGGCGAGTCCGAGAACACGCTGCGCAAGAGCATGACGTCCAACGATC
CCAAGGTGCGGTTCGTGTACCTGGGCCGTCGCCTCGACCGGGCGGTCGGGGACGAGGTGGACAAGCTGGGCCTGCGCGGC
ATCGGCGTCCTCCCCGAGCGGGGGCGCTGGTACCCGTCGCTGACCCTGGGCGCCAACTTCGTCGGCTTCACCAAGCTCGG
CGAGAACGACGCGATCGTGGGCGCCGGCGGCCTGGAGCTGGCCTACGACAGCGTGCTGCGCGGGACGGACGGGCGCCGCC
AGATCGAGGCCGACCCGTCCGGGCGGGAGATCCCCTCGGCACAGAGCGTGGAGAAGGACCCGGTCAGCGGCTCCACACTG
CGCCTCACCATCGACAACTACATCCAGTGGGACGCCCAGAGCGCGATCGCTGAGGCGGTGCGGACCTCGGAGGCGGACGG
CGGCACGATCGTCGTGATGAACCCGAAGACGGGTGACCTGCTCGCGATGGCCGACGCGCCCCAGTTCGACCCGAACAACA
TCACCTCCCGGGACATCGACGCGATCGGGAACCGCTCGACCGGCCAGGCCTTCGAGCCCGGCAGCGTCAACAAGGTCATC
ACCATGGCCGCGGCACTTGACCGGAACCTGATCGAGACGACGACCCCGATCACCGTGCCGCCGTCCATCGAGCGGGGCGG
GGTGACGATCACGGACTCGGAGCCGCACGGCACCGAGCACCTCACCGCGGCCGGCGTGCTCGCCCGGTCCAGCAACATCG
GGACGGTGCTAGTCGCCGAGCGGGTCGGCAACGACAACCTCGAGCAGATGATGCGCGCGTTCGGGCTCGGCAAGGCGACC
GAGGTCGACTTCCCCGGTGAGACCGCCGGCATCCTGCCGCCGGCCGCGGACTGGTCGGGCAGCCAGGCCGCGACCATCGC
CTACGGCCAGGGCACCTCGGCCACGGCCCTGCAGATGGCGTCGGTCTACGCGACCGTGGCGAACGGCGGCATGCGGGTCG
CGCCGCGGCTGGTGGACGCGATCACCGGCCCGGACGGGGTCACACGGCCCACCCCGCGGGCGCCCGAGCGCCGGGTGGTC
TCCCCGGAGACCGCCTCCACGCTCACCCGCATGCTCGAGGCCGTCGCGACGACACAGGGCACCGCCCCCGCCGCCGAGGT
CGCCGGGTACCGGGTCGCCGGCAAGACGGGCACGGCGAAGCGGTACGACCCGGTGAACGGCGGCTACGACGGCTACGTCT
CGACGTTCATCGGCTTCGCCCCGGCCGACGACCCCCAGGTCGTCGTGGAGGTCGTGCTCGACCACCCGCGCAAGGGCTTC
TACGGCGGCGAGGTCGCCGCGCCCGTGTTCAAGCGGGTGATGAGCTTCGCCCTCACCACGCTGGGTGTGCCGCCGCCGGG
GACGAGACCCGAACCGCTGGTCCTCGACCTCGACCACTGA

Upstream 100 bases:

>100_bases
GTGGCACGTCCACCCAGCCCGCGGCTGGCGGCGAGGCGGCCGCGTCCGCCGCCGATCCGCAGGCCCGTACCGGTACCGAC
GGAGAGGCGGGAGCCGGTCA

Downstream 100 bases:

>100_bases
GAACGGGCGAGCGCGGGACGTCGCGCGCCCGTCCACGCCGGGGGCCGGGGGCCGGGAGCCGCCGCCGGTTTGGCCCAGGC
TGTCCCGACACCTGCGCGTC

Product: peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]

Number of amino acids: Translated: 839; Mature: 838

Protein sequence:

>839_residues
MSQTTRGPSSGRGRNRLRLVTNPHPGSPDSRSARHDGDDLLDPSVRRFSGRDPDGGRGRMTPPPRGGDRHGDDRRGYDAA
RPRNDRRQDARRRDDRDDRDDRDDRDDRDDRDDRDDRDDRDELDEQTWDDAAAEATERAARRPRPRPAAAGRERRAATAR
AGRSSPRVSPLRSAAAGSATPREQLRRDQAARATSARTTSARGAAGRRNPTRGAASRTTSGRIPPVRRPHPSSGGAGRNR
ATSIRRGLGGAPPRPPRPFVLASPRRRVRVSVVLMIAVLVVIAGRLAQLQGFASSNYAEQAEQQRLRKSVLPADRGMITD
RHGDALAQDVERRAVYADPWLMNEAQVVDAARKLAPLLGESENTLRKSMTSNDPKVRFVYLGRRLDRAVGDEVDKLGLRG
IGVLPERGRWYPSLTLGANFVGFTKLGENDAIVGAGGLELAYDSVLRGTDGRRQIEADPSGREIPSAQSVEKDPVSGSTL
RLTIDNYIQWDAQSAIAEAVRTSEADGGTIVVMNPKTGDLLAMADAPQFDPNNITSRDIDAIGNRSTGQAFEPGSVNKVI
TMAAALDRNLIETTTPITVPPSIERGGVTITDSEPHGTEHLTAAGVLARSSNIGTVLVAERVGNDNLEQMMRAFGLGKAT
EVDFPGETAGILPPAADWSGSQAATIAYGQGTSATALQMASVYATVANGGMRVAPRLVDAITGPDGVTRPTPRAPERRVV
SPETASTLTRMLEAVATTQGTAPAAEVAGYRVAGKTGTAKRYDPVNGGYDGYVSTFIGFAPADDPQVVVEVVLDHPRKGF
YGGEVAAPVFKRVMSFALTTLGVPPPGTRPEPLVLDLDH

Sequences:

>Translated_839_residues
MSQTTRGPSSGRGRNRLRLVTNPHPGSPDSRSARHDGDDLLDPSVRRFSGRDPDGGRGRMTPPPRGGDRHGDDRRGYDAA
RPRNDRRQDARRRDDRDDRDDRDDRDDRDDRDDRDDRDDRDELDEQTWDDAAAEATERAARRPRPRPAAAGRERRAATAR
AGRSSPRVSPLRSAAAGSATPREQLRRDQAARATSARTTSARGAAGRRNPTRGAASRTTSGRIPPVRRPHPSSGGAGRNR
ATSIRRGLGGAPPRPPRPFVLASPRRRVRVSVVLMIAVLVVIAGRLAQLQGFASSNYAEQAEQQRLRKSVLPADRGMITD
RHGDALAQDVERRAVYADPWLMNEAQVVDAARKLAPLLGESENTLRKSMTSNDPKVRFVYLGRRLDRAVGDEVDKLGLRG
IGVLPERGRWYPSLTLGANFVGFTKLGENDAIVGAGGLELAYDSVLRGTDGRRQIEADPSGREIPSAQSVEKDPVSGSTL
RLTIDNYIQWDAQSAIAEAVRTSEADGGTIVVMNPKTGDLLAMADAPQFDPNNITSRDIDAIGNRSTGQAFEPGSVNKVI
TMAAALDRNLIETTTPITVPPSIERGGVTITDSEPHGTEHLTAAGVLARSSNIGTVLVAERVGNDNLEQMMRAFGLGKAT
EVDFPGETAGILPPAADWSGSQAATIAYGQGTSATALQMASVYATVANGGMRVAPRLVDAITGPDGVTRPTPRAPERRVV
SPETASTLTRMLEAVATTQGTAPAAEVAGYRVAGKTGTAKRYDPVNGGYDGYVSTFIGFAPADDPQVVVEVVLDHPRKGF
YGGEVAAPVFKRVMSFALTTLGVPPPGTRPEPLVLDLDH
>Mature_838_residues
SQTTRGPSSGRGRNRLRLVTNPHPGSPDSRSARHDGDDLLDPSVRRFSGRDPDGGRGRMTPPPRGGDRHGDDRRGYDAAR
PRNDRRQDARRRDDRDDRDDRDDRDDRDDRDDRDDRDDRDELDEQTWDDAAAEATERAARRPRPRPAAAGRERRAATARA
GRSSPRVSPLRSAAAGSATPREQLRRDQAARATSARTTSARGAAGRRNPTRGAASRTTSGRIPPVRRPHPSSGGAGRNRA
TSIRRGLGGAPPRPPRPFVLASPRRRVRVSVVLMIAVLVVIAGRLAQLQGFASSNYAEQAEQQRLRKSVLPADRGMITDR
HGDALAQDVERRAVYADPWLMNEAQVVDAARKLAPLLGESENTLRKSMTSNDPKVRFVYLGRRLDRAVGDEVDKLGLRGI
GVLPERGRWYPSLTLGANFVGFTKLGENDAIVGAGGLELAYDSVLRGTDGRRQIEADPSGREIPSAQSVEKDPVSGSTLR
LTIDNYIQWDAQSAIAEAVRTSEADGGTIVVMNPKTGDLLAMADAPQFDPNNITSRDIDAIGNRSTGQAFEPGSVNKVIT
MAAALDRNLIETTTPITVPPSIERGGVTITDSEPHGTEHLTAAGVLARSSNIGTVLVAERVGNDNLEQMMRAFGLGKATE
VDFPGETAGILPPAADWSGSQAATIAYGQGTSATALQMASVYATVANGGMRVAPRLVDAITGPDGVTRPTPRAPERRVVS
PETASTLTRMLEAVATTQGTAPAAEVAGYRVAGKTGTAKRYDPVNGGYDGYVSTFIGFAPADDPQVVVEVVLDHPRKGFY
GGEVAAPVFKRVMSFALTTLGVPPPGTRPEPLVLDLDH

Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=557, Percent_Identity=34.1113105924596, Blast_Score=278, Evalue=9e-76,
Organism=Escherichia coli, GI1786854, Length=611, Percent_Identity=24.2225859247136, Blast_Score=117, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: =2.4.1.129 [H]

Molecular weight: Translated: 90050; Mature: 89919

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTTRGPSSGRGRNRLRLVTNPHPGSPDSRSARHDGDDLLDPSVRRFSGRDPDGGRGRM
CCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHCCCHHHHHCCCCCCCCCCCC
TPPPRGGDRHGDDRRGYDAARPRNDRRQDARRRDDRDDRDDRDDRDDRDDRDDRDDRDDR
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCH
DELDEQTWDDAAAEATERAARRPRPRPAAAGRERRAATARAGRSSPRVSPLRSAAAGSAT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHCCCCC
PREQLRRDQAARATSARTTSARGAAGRRNPTRGAASRTTSGRIPPVRRPHPSSGGAGRNR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
ATSIRRGLGGAPPRPPRPFVLASPRRRVRVSVVLMIAVLVVIAGRLAQLQGFASSNYAEQ
HHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AEQQRLRKSVLPADRGMITDRHGDALAQDVERRAVYADPWLMNEAQVVDAARKLAPLLGE
HHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCC
SENTLRKSMTSNDPKVRFVYLGRRLDRAVGDEVDKLGLRGIGVLPERGRWYPSLTLGANF
CHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCE
VGFTKLGENDAIVGAGGLELAYDSVLRGTDGRRQIEADPSGREIPSAQSVEKDPVSGSTL
EEEEEECCCCCEEECCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEE
RLTIDNYIQWDAQSAIAEAVRTSEADGGTIVVMNPKTGDLLAMADAPQFDPNNITSRDID
EEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCHHHH
AIGNRSTGQAFEPGSVNKVITMAAALDRNLIETTTPITVPPSIERGGVTITDSEPHGTEH
HHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHCCCCEECCCCCCCCCEEEECCCCCCCHH
LTAAGVLARSSNIGTVLVAERVGNDNLEQMMRAFGLGKATEVDFPGETAGILPPAADWSG
HHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
SQAATIAYGQGTSATALQMASVYATVANGGMRVAPRLVDAITGPDGVTRPTPRAPERRVV
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SPETASTLTRMLEAVATTQGTAPAAEVAGYRVAGKTGTAKRYDPVNGGYDGYVSTFIGFA
CCHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHHHCCC
PADDPQVVVEVVLDHPRKGFYGGEVAAPVFKRVMSFALTTLGVPPPGTRPEPLVLDLDH
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCC
>Mature Secondary Structure 
SQTTRGPSSGRGRNRLRLVTNPHPGSPDSRSARHDGDDLLDPSVRRFSGRDPDGGRGRM
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHCCCHHHHHCCCCCCCCCCCC
TPPPRGGDRHGDDRRGYDAARPRNDRRQDARRRDDRDDRDDRDDRDDRDDRDDRDDRDDR
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCH
DELDEQTWDDAAAEATERAARRPRPRPAAAGRERRAATARAGRSSPRVSPLRSAAAGSAT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHCCCCC
PREQLRRDQAARATSARTTSARGAAGRRNPTRGAASRTTSGRIPPVRRPHPSSGGAGRNR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
ATSIRRGLGGAPPRPPRPFVLASPRRRVRVSVVLMIAVLVVIAGRLAQLQGFASSNYAEQ
HHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AEQQRLRKSVLPADRGMITDRHGDALAQDVERRAVYADPWLMNEAQVVDAARKLAPLLGE
HHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCC
SENTLRKSMTSNDPKVRFVYLGRRLDRAVGDEVDKLGLRGIGVLPERGRWYPSLTLGANF
CHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCE
VGFTKLGENDAIVGAGGLELAYDSVLRGTDGRRQIEADPSGREIPSAQSVEKDPVSGSTL
EEEEEECCCCCEEECCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEE
RLTIDNYIQWDAQSAIAEAVRTSEADGGTIVVMNPKTGDLLAMADAPQFDPNNITSRDID
EEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCHHHH
AIGNRSTGQAFEPGSVNKVITMAAALDRNLIETTTPITVPPSIERGGVTITDSEPHGTEH
HHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHCCCCEECCCCCCCCCEEEECCCCCCCHH
LTAAGVLARSSNIGTVLVAERVGNDNLEQMMRAFGLGKATEVDFPGETAGILPPAADWSG
HHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
SQAATIAYGQGTSATALQMASVYATVANGGMRVAPRLVDAITGPDGVTRPTPRAPERRVV
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SPETASTLTRMLEAVATTQGTAPAAEVAGYRVAGKTGTAKRYDPVNGGYDGYVSTFIGFA
CCHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHHHCCC
PADDPQVVVEVVLDHPRKGFYGGEVAAPVFKRVMSFALTTLGVPPPGTRPEPLVLDLDH
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]