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The map label for this gene is ftsW [C]

Identifier: 158316856

GI number: 158316856

Start: 6103245

End: 6104669

Strand: Reverse

Name: ftsW [C]

Synonym: Franean1_5099

Alternate gene names: 158316856

Gene position: 6104669-6103245 (Counterclockwise)

Preceding gene: 158316857

Following gene: 158316855

Centisome position: 67.97

GC content: 73.47

Gene sequence:

>1425_bases
ATGACGGGTGCGCGAACCACCGGAACGGGGACGGCCGTCGCCGGGTCGAGGCCCGCGGGGAGCACCAGCGCGGGCACGAC
CGGTGCGGGCGGGGCCGGCGCGGCGGGCTCCGCGGCCGCCACCGACACGGGCGGCGCCGGCGGGCCGAGCACCGGCGGGC
CGGAGGCCACCGGGGCCAGGCGGGGCTGGGTCGGCGACCCCCGCACGCCCGTCCTCGACCGCCCGCTGGCCTCGTACTAC
CTGCTGCTCTCCTCCGCCGGCCTGCTGCTGCTACTCGGCCTGGTGATGGTGCTCTCGGCGTCCGCCCCGCGGTCGTTCCA
GGACTTCGGCTCGGCCTACACGCTGTTCCTGCGCCAGGCGACCTGGGCTGGCATCGGCTTCCCGCTGCTGCTGGTGGCGA
GCCGCCTGCCGATCCGCGTGTTCCGGGCCGCCGCCTACCCATTGCTGGGCGTGACCGTCCTGCTGCTGATGGCGGTGCTC
GTCCCGGGGATCGGGCATGTCGAGAACGGTTCCCGGCAGTGGATCCCGATCGGCCCGTACACCCTGCAGCCGAGCGAGTT
CGCCAAGATCGCCCTGGTGCTGTGGTGCTCGGACGTCCTCGTCCGCAAGCGCCGGCTGCTGGTCAACTGGAAGCACCTGA
TCATCCCGGTGGTGCCCGGCTTCCTGTTCGTCGACCTGCTGCTCATGCTCGAGCCCGATCTGGGCGGCTCGATCTGTGTC
ACCGTCGTCCCGCTGGCGGTGCTCTGGGTGATCGGCACCCCGCTGCGGATCTACGCCGGACTGCTCGGCGGCATGGTCGC
CGGCGCCAGCGTCCTGGCGATCAGCGCGCCGTACCGGCTGGAACGGCTGATGTCCTTCCGGGATCCCTTCGCCGACCCGA
ACAACACCGGCTTCCAGGCCGTCCACGGCATCTACGCGCTGTCGTCCGGCGGCTGGTGGGGGGAGGGGCTGGGCGCCTCG
CGGGAGAAGTGGCCGGACCTGCTGCCCGCCGTGCACACCGACTTCATCCTCGCGATCATCGGCGAGGAGCTCGGGCTGCT
CGGGAGCCTGGTGACCGTCACGCTGTTCGGCGTGCTGGGCTACGCGGGCCTGCGGATCGCGCACCGCAGCGACGACCTGT
TCATCCGGCTGGCCGCCACGGCGGTCACCGCCTGGATCATCGCGCAGGCCGTGGTGAACATGGGTGCGGTCGTGGGACTG
CTGCCGATCACCGGGGTGACCTTGCCACTGGTGTCCTTCGGCGGATCGGCGCTGCTGCCGACGATGGGCGCGCTGGGCAT
GCTGCTGGCCTTCGCCCGCCGCGAGCCGGACGCCGTCGTCTACCTCGCGGAGCGGGCCGAGGCACGCCGAGCGGGGCGGG
CCGGCCGGGGGTGGCTGCGCCGCCGCCGCGCCGCGCGGGCCGAGACCCCCGAAACGGTGGTCTGA

Upstream 100 bases:

>100_bases
GCGGCGACCTGTTCGCCGCGGCCGTGCGAGCGCGGGGAGGCTGACCGCCGGCGCTCTCCCTCCCAGCGCGGCACCGGAGA
GGGGGAGCGTGAGTGAGCGC

Downstream 100 bases:

>100_bases
GCGGCCGCGACGAGGCGTCCGCGTGTTCCACCGACCATGTTGCGTGGACGCCGCCCCGATGTGGAATCGTCAGGGCCGAT
GTTGCGAAGTGTGCTGCTCG

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MTGARTTGTGTAVAGSRPAGSTSAGTTGAGGAGAAGSAAATDTGGAGGPSTGGPEATGARRGWVGDPRTPVLDRPLASYY
LLLSSAGLLLLLGLVMVLSASAPRSFQDFGSAYTLFLRQATWAGIGFPLLLVASRLPIRVFRAAAYPLLGVTVLLLMAVL
VPGIGHVENGSRQWIPIGPYTLQPSEFAKIALVLWCSDVLVRKRRLLVNWKHLIIPVVPGFLFVDLLLMLEPDLGGSICV
TVVPLAVLWVIGTPLRIYAGLLGGMVAGASVLAISAPYRLERLMSFRDPFADPNNTGFQAVHGIYALSSGGWWGEGLGAS
REKWPDLLPAVHTDFILAIIGEELGLLGSLVTVTLFGVLGYAGLRIAHRSDDLFIRLAATAVTAWIIAQAVVNMGAVVGL
LPITGVTLPLVSFGGSALLPTMGALGMLLAFARREPDAVVYLAERAEARRAGRAGRGWLRRRRAARAETPETVV

Sequences:

>Translated_474_residues
MTGARTTGTGTAVAGSRPAGSTSAGTTGAGGAGAAGSAAATDTGGAGGPSTGGPEATGARRGWVGDPRTPVLDRPLASYY
LLLSSAGLLLLLGLVMVLSASAPRSFQDFGSAYTLFLRQATWAGIGFPLLLVASRLPIRVFRAAAYPLLGVTVLLLMAVL
VPGIGHVENGSRQWIPIGPYTLQPSEFAKIALVLWCSDVLVRKRRLLVNWKHLIIPVVPGFLFVDLLLMLEPDLGGSICV
TVVPLAVLWVIGTPLRIYAGLLGGMVAGASVLAISAPYRLERLMSFRDPFADPNNTGFQAVHGIYALSSGGWWGEGLGAS
REKWPDLLPAVHTDFILAIIGEELGLLGSLVTVTLFGVLGYAGLRIAHRSDDLFIRLAATAVTAWIIAQAVVNMGAVVGL
LPITGVTLPLVSFGGSALLPTMGALGMLLAFARREPDAVVYLAERAEARRAGRAGRGWLRRRRAARAETPETVV
>Mature_473_residues
TGARTTGTGTAVAGSRPAGSTSAGTTGAGGAGAAGSAAATDTGGAGGPSTGGPEATGARRGWVGDPRTPVLDRPLASYYL
LLSSAGLLLLLGLVMVLSASAPRSFQDFGSAYTLFLRQATWAGIGFPLLLVASRLPIRVFRAAAYPLLGVTVLLLMAVLV
PGIGHVENGSRQWIPIGPYTLQPSEFAKIALVLWCSDVLVRKRRLLVNWKHLIIPVVPGFLFVDLLLMLEPDLGGSICVT
VVPLAVLWVIGTPLRIYAGLLGGMVAGASVLAISAPYRLERLMSFRDPFADPNNTGFQAVHGIYALSSGGWWGEGLGASR
EKWPDLLPAVHTDFILAIIGEELGLLGSLVTVTLFGVLGYAGLRIAHRSDDLFIRLAATAVTAWIIAQAVVNMGAVVGLL
PITGVTLPLVSFGGSALLPTMGALGMLLAFARREPDAVVYLAERAEARRAGRAGRGWLRRRRAARAETPETVV

Specific function: This Is A Septum-Peptidoglycan Biosynthetic Protein, Involved In Cell Wall Formation. Plays A Role In The Stabilization Of The Ftsz Ring During Cell Division. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=375, Percent_Identity=33.8666666666667, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1786853, Length=326, Percent_Identity=33.1288343558282, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 49484; Mature: 49352

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGARTTGTGTAVAGSRPAGSTSAGTTGAGGAGAAGSAAATDTGGAGGPSTGGPEATGAR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RGWVGDPRTPVLDRPLASYYLLLSSAGLLLLLGLVMVLSASAPRSFQDFGSAYTLFLRQA
CCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
TWAGIGFPLLLVASRLPIRVFRAAAYPLLGVTVLLLMAVLVPGIGHVENGSRQWIPIGPY
HHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCE
TLQPSEFAKIALVLWCSDVLVRKRRLLVNWKHLIIPVVPGFLFVDLLLMLEPDLGGSICV
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
TVVPLAVLWVIGTPLRIYAGLLGGMVAGASVLAISAPYRLERLMSFRDPFADPNNTGFQA
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHCCCCCCCCCCHHH
VHGIYALSSGGWWGEGLGASREKWPDLLPAVHTDFILAIIGEELGLLGSLVTVTLFGVLG
HHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAGLRIAHRSDDLFIRLAATAVTAWIIAQAVVNMGAVVGLLPITGVTLPLVSFGGSALLP
HHHEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
TMGALGMLLAFARREPDAVVYLAERAEARRAGRAGRGWLRRRRAARAETPETVV
HHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TGARTTGTGTAVAGSRPAGSTSAGTTGAGGAGAAGSAAATDTGGAGGPSTGGPEATGAR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RGWVGDPRTPVLDRPLASYYLLLSSAGLLLLLGLVMVLSASAPRSFQDFGSAYTLFLRQA
CCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
TWAGIGFPLLLVASRLPIRVFRAAAYPLLGVTVLLLMAVLVPGIGHVENGSRQWIPIGPY
HHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCE
TLQPSEFAKIALVLWCSDVLVRKRRLLVNWKHLIIPVVPGFLFVDLLLMLEPDLGGSICV
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
TVVPLAVLWVIGTPLRIYAGLLGGMVAGASVLAISAPYRLERLMSFRDPFADPNNTGFQA
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHCCCCCCCCCCHHH
VHGIYALSSGGWWGEGLGASREKWPDLLPAVHTDFILAIIGEELGLLGSLVTVTLFGVLG
HHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAGLRIAHRSDDLFIRLAATAVTAWIIAQAVVNMGAVVGLLPITGVTLPLVSFGGSALLP
HHHEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
TMGALGMLLAFARREPDAVVYLAERAEARRAGRAGRGWLRRRRAARAETPETVV
HHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]