Click here to switch to the map view.

The map label for this gene is pgsA1 [H]

Identifier: 158316765

GI number: 158316765

Start: 6000263

End: 6000865

Strand: Reverse

Name: pgsA1 [H]

Synonym: Franean1_5003

Alternate gene names: 158316765

Gene position: 6000865-6000263 (Counterclockwise)

Preceding gene: 158316766

Following gene: 158316764

Centisome position: 66.81

GC content: 72.31

Gene sequence:

>603_bases
GTGACGGCGGAGACGCAGGCCTCCGACCGGATCTGGACCATCCCGAACCTGCTGTCCGGTCTGCGCCTGCTGGGCGTGCC
GCTCTTCCTCTGGCTCGCGCTGGGCCCGGAGGCGGACGGTGCCGCGCTGGGCGTGCTCGCCTTCGCCGGCGTCAGCGACT
ACCTGGACGGCAAGCTCGCCCGGGTGCTGAACCAGACCAGCCGCCTCGGGGTGACTCTCGACCCGCTGGCCGACCGGCTC
TACATCTTCGCGACCATCGTCGCGCTCACCCTGCGCGACATCGTCCCGCTGTGGTTCGCGTTGGCGCTCGTCGGCCGGGA
CGTCGCGCTGCTGGGCCTGGTGCCCGTGCTGCGCCGGCTCGGGGTGGGCACCACGCTGCCCGTCCACTACCTCGGCAAGG
CGGCCACCTTCAACCTGCTGTACGCCTTTCCGCTCCTGCTGCTGTCCGCCGGCGACTCGTGGCTGGCGACGGCGGCCCGC
CCGCTCGGGTGGGCGTTCGCCATCTGGGGTATCGCTCTTTACTGGTGGTCCGGCCTCCTCTACGCAGAACAGGCCCGCCG
GCTGGCCGGGGAACGCGCCCGCCTGGCCGCGGCGCGAAAATAG

Upstream 100 bases:

>100_bases
CATCCGCTAGCGTCAGAGCCGACGACCCGCGTCCAGCGGTCGGCGCGCGAGCCGTCGGCGCCCGTCTTCGTGCGGCCGGG
TCGGGGAGGAGGGACGCGGC

Downstream 100 bases:

>100_bases
GGAGGTAACCCTTGAGAGCCGTCGTGATGGCGGGCGGCGAGGGCACCCGGCTGCGGCCGCTGACCGCGAACCTGCCGAAG
CCCCTGCTGCCGGTCGTCAA

Product: CDP-alcohol phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MTAETQASDRIWTIPNLLSGLRLLGVPLFLWLALGPEADGAALGVLAFAGVSDYLDGKLARVLNQTSRLGVTLDPLADRL
YIFATIVALTLRDIVPLWFALALVGRDVALLGLVPVLRRLGVGTTLPVHYLGKAATFNLLYAFPLLLLSAGDSWLATAAR
PLGWAFAIWGIALYWWSGLLYAEQARRLAGERARLAAARK

Sequences:

>Translated_200_residues
MTAETQASDRIWTIPNLLSGLRLLGVPLFLWLALGPEADGAALGVLAFAGVSDYLDGKLARVLNQTSRLGVTLDPLADRL
YIFATIVALTLRDIVPLWFALALVGRDVALLGLVPVLRRLGVGTTLPVHYLGKAATFNLLYAFPLLLLSAGDSWLATAAR
PLGWAFAIWGIALYWWSGLLYAEQARRLAGERARLAAARK
>Mature_199_residues
TAETQASDRIWTIPNLLSGLRLLGVPLFLWLALGPEADGAALGVLAFAGVSDYLDGKLARVLNQTSRLGVTLDPLADRLY
IFATIVALTLRDIVPLWFALALVGRDVALLGLVPVLRRLGVGTTLPVHYLGKAATFNLLYAFPLLLLSAGDSWLATAARP
LGWAFAIWGIALYWWSGLLYAEQARRLAGERARLAAARK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI188536108, Length=108, Percent_Identity=43.5185185185185, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI10092647, Length=135, Percent_Identity=40.7407407407407, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1788220, Length=129, Percent_Identity=30.2325581395349, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320059, Length=133, Percent_Identity=33.0827067669173, Blast_Score=62, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24650130, Length=115, Percent_Identity=36.5217391304348, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650126, Length=115, Percent_Identity=36.5217391304348, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650128, Length=115, Percent_Identity=36.5217391304348, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21636; Mature: 21505

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAETQASDRIWTIPNLLSGLRLLGVPLFLWLALGPEADGAALGVLAFAGVSDYLDGKLA
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
RVLNQTSRLGVTLDPLADRLYIFATIVALTLRDIVPLWFALALVGRDVALLGLVPVLRRL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
GVGTTLPVHYLGKAATFNLLYAFPLLLLSAGDSWLATAARPLGWAFAIWGIALYWWSGLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAEQARRLAGERARLAAARK
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAETQASDRIWTIPNLLSGLRLLGVPLFLWLALGPEADGAALGVLAFAGVSDYLDGKLA
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
RVLNQTSRLGVTLDPLADRLYIFATIVALTLRDIVPLWFALALVGRDVALLGLVPVLRRL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
GVGTTLPVHYLGKAATFNLLYAFPLLLLSAGDSWLATAARPLGWAFAIWGIALYWWSGLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAEQARRLAGERARLAAARK
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]