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The map label for this gene is polC [H]

Identifier: 158316676

GI number: 158316676

Start: 5899607

End: 5900776

Strand: Reverse

Name: polC [H]

Synonym: Franean1_4913

Alternate gene names: 158316676

Gene position: 5900776-5899607 (Counterclockwise)

Preceding gene: 158316678

Following gene: 158316672

Centisome position: 65.7

GC content: 71.03

Gene sequence:

>1170_bases
GTGGCCGTCGACGAGCGACTTAAAACAACGGACACACAATACCATCCGCGATCACGGCCGGATTCGTTGTTTCCCTCGCG
TTGCCCTCCATCCGCACCAGGTTCGCTCCGTCCCCGCACTGCTCCGGGCAGCGCGGCGCCGGACCGTCGGGGGTCTGCGC
CATCATCTGCGGCTGTGAGTGCTGAGGTTCTTGCCCCGCCCGGCTTCGCCGCACGTTTTCGTCGGCCGTACGCGGTGGTG
GACGTCGAGACCACGGGCCTGTCCCCGACGAGGGACAGGGTGCTGTCGGTAGCGGTCGTCCTGACCGCCGCCGACGGCAC
CGTCGAACACCGCTGGTCAACCCTCCTGGATCCCGGATGTGATCCCGGCCCCGTCCATATTCACGGTCTGACCAGGCAGC
GCCTGGCCGGGAGCCCGACGTTCGCCGCCGTCGCCGACGAGGTCGCCGGCCTGCTCGCCGGGCGGGTGCTCGTCGCGCAC
AACGCGGCCTTCGACTGGCGGATGCTAGCCGGCGAGGCCATGCGGATCGGGACGACGATCCCGGTCGAGTGGCGGCTGTG
CACGCTGACGTTGGCCAGTCGGCTCGGCCTGGAGCTGCCGAGCCTGCGCCTGGCCTCGCTCGCCGCGTACTGGGGCGTCG
TCCAGCGGCGGGCCCATGACGCGCAGGATGACGCCGAGGTGCTGGCGGCCTTGTTGCCCCGCATCCTGCAACGTGCCGCC
GACCAGTACCTGGAGCTGCCGCTCACGCGCTGCGGCGTCGACCACGACGGCGTCACGGTGCGCCCGCCGCGCTTCGCCGC
CGCGGGCCGCACGCCGCCGTGCCGTTATCGAAACCCCGGGCGGCTCGATCCCGGTGCGGCGCTGGTCCAGGGAATGCGCG
TCGCTTTCAGCGGCCCCACGCGGACGGAACGCGGCGAGCTCGTCGGCCGGGCGGTCGCCGCAGGCCTGCATGTGACGGAA
ACCGTGAGTCGGCGCACAAGTCTTCTGGTGACCAATGACGCTCGCGGCGTGACCCGGAAGGTCCGCACCGCCGCGTTGTT
GAACACACCCGTACGAGGAGAGGAAGATTTCCTGGAATTGCTCGCGGCCGTTCGCCCAGGAATTCTCGTCCCGGCTGCCG
CACCCGTTCGCCGTGACCGCCGGCCGCGGCGCCCGACCCCGGACGCGTGA

Upstream 100 bases:

>100_bases
CCGCCGCTGAACTGCCGCACCTGGTCGTCCCCGACAAACGACAGGTGCGCGGCGGGCCGCGGTCGACGGCACCGGCCGGG
CCCAGACAGGAATCGCCCCG

Downstream 100 bases:

>100_bases
CGGCCGGGCGAGTCCGTGGACTCGCCCGGCCGTCACCGTGGGGGCTGCTCGGTCGGCGGTGGAGGTCAGTGCCGAACGGA
GGTGCGGCCCCGGCTGTGCA

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MAVDERLKTTDTQYHPRSRPDSLFPSRCPPSAPGSLRPRTAPGSAAPDRRGSAPSSAAVSAEVLAPPGFAARFRRPYAVV
DVETTGLSPTRDRVLSVAVVLTAADGTVEHRWSTLLDPGCDPGPVHIHGLTRQRLAGSPTFAAVADEVAGLLAGRVLVAH
NAAFDWRMLAGEAMRIGTTIPVEWRLCTLTLASRLGLELPSLRLASLAAYWGVVQRRAHDAQDDAEVLAALLPRILQRAA
DQYLELPLTRCGVDHDGVTVRPPRFAAAGRTPPCRYRNPGRLDPGAALVQGMRVAFSGPTRTERGELVGRAVAAGLHVTE
TVSRRTSLLVTNDARGVTRKVRTAALLNTPVRGEEDFLELLAAVRPGILVPAAAPVRRDRRPRRPTPDA

Sequences:

>Translated_389_residues
MAVDERLKTTDTQYHPRSRPDSLFPSRCPPSAPGSLRPRTAPGSAAPDRRGSAPSSAAVSAEVLAPPGFAARFRRPYAVV
DVETTGLSPTRDRVLSVAVVLTAADGTVEHRWSTLLDPGCDPGPVHIHGLTRQRLAGSPTFAAVADEVAGLLAGRVLVAH
NAAFDWRMLAGEAMRIGTTIPVEWRLCTLTLASRLGLELPSLRLASLAAYWGVVQRRAHDAQDDAEVLAALLPRILQRAA
DQYLELPLTRCGVDHDGVTVRPPRFAAAGRTPPCRYRNPGRLDPGAALVQGMRVAFSGPTRTERGELVGRAVAAGLHVTE
TVSRRTSLLVTNDARGVTRKVRTAALLNTPVRGEEDFLELLAAVRPGILVPAAAPVRRDRRPRRPTPDA
>Mature_388_residues
AVDERLKTTDTQYHPRSRPDSLFPSRCPPSAPGSLRPRTAPGSAAPDRRGSAPSSAAVSAEVLAPPGFAARFRRPYAVVD
VETTGLSPTRDRVLSVAVVLTAADGTVEHRWSTLLDPGCDPGPVHIHGLTRQRLAGSPTFAAVADEVAGLLAGRVLVAHN
AAFDWRMLAGEAMRIGTTIPVEWRLCTLTLASRLGLELPSLRLASLAAYWGVVQRRAHDAQDDAEVLAALLPRILQRAAD
QYLELPLTRCGVDHDGVTVRPPRFAAAGRTPPCRYRNPGRLDPGAALVQGMRVAFSGPTRTERGELVGRAVAAGLHVTET
VSRRTSLLVTNDARGVTRKVRTAALLNTPVRGEEDFLELLAAVRPGILVPAAAPVRRDRRPRRPTPDA

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR016027
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 41716; Mature: 41585

Theoretical pI: Translated: 11.14; Mature: 11.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVDERLKTTDTQYHPRSRPDSLFPSRCPPSAPGSLRPRTAPGSAAPDRRGSAPSSAAVS
CCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCE
AEVLAPPGFAARFRRPYAVVDVETTGLSPTRDRVLSVAVVLTAADGTVEHRWSTLLDPGC
EEEECCCCHHHHHCCCEEEEEEECCCCCHHHHHHEEEEEEEEECCCCHHHHHHHHCCCCC
DPGPVHIHGLTRQRLAGSPTFAAVADEVAGLLAGRVLVAHNAAFDWRMLAGEAMRIGTTI
CCCCEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHCCCCEECCCCC
PVEWRLCTLTLASRLGLELPSLRLASLAAYWGVVQRRAHDAQDDAEVLAALLPRILQRAA
CCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
DQYLELPLTRCGVDHDGVTVRPPRFAAAGRTPPCRYRNPGRLDPGAALVQGMRVAFSGPT
HHHHHCCHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCC
RTERGELVGRAVAAGLHVTETVSRRTSLLVTNDARGVTRKVRTAALLNTPVRGEEDFLEL
CCHHHHHHHHHHHHCCHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHH
LAAVRPGILVPAAAPVRRDRRPRRPTPDA
HHHHCCCEEECCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
AVDERLKTTDTQYHPRSRPDSLFPSRCPPSAPGSLRPRTAPGSAAPDRRGSAPSSAAVS
CCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCE
AEVLAPPGFAARFRRPYAVVDVETTGLSPTRDRVLSVAVVLTAADGTVEHRWSTLLDPGC
EEEECCCCHHHHHCCCEEEEEEECCCCCHHHHHHEEEEEEEEECCCCHHHHHHHHCCCCC
DPGPVHIHGLTRQRLAGSPTFAAVADEVAGLLAGRVLVAHNAAFDWRMLAGEAMRIGTTI
CCCCEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHCCCCEECCCCC
PVEWRLCTLTLASRLGLELPSLRLASLAAYWGVVQRRAHDAQDDAEVLAALLPRILQRAA
CCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
DQYLELPLTRCGVDHDGVTVRPPRFAAAGRTPPCRYRNPGRLDPGAALVQGMRVAFSGPT
HHHHHCCHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCC
RTERGELVGRAVAAGLHVTETVSRRTSLLVTNDARGVTRKVRTAALLNTPVRGEEDFLEL
CCHHHHHHHHHHHHCCHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHH
LAAVRPGILVPAAAPVRRDRRPRRPTPDA
HHHHCCCEEECCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]