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The map label for this gene is rifF [H]

Identifier: 158316599

GI number: 158316599

Start: 5777291

End: 5778097

Strand: Reverse

Name: rifF [H]

Synonym: Franean1_4835

Alternate gene names: 158316599

Gene position: 5778097-5777291 (Counterclockwise)

Preceding gene: 158316600

Following gene: 158316598

Centisome position: 64.33

GC content: 72.99

Gene sequence:

>807_bases
GTGTTTGACGTCGAGGCGTACCTGAAGGCGCTCGACCACCGTGGCCCGGCCGACGCGAGCCCTGAGACGCTGCGCCGCCT
GCACCACGCCCACCTGCGGACCGTGCCCTACGACAGCGAGCTGAACTCCACCCGCGGCACGGACCTGTGGAAGGGCGTCG
ACATCGACGCCGACGCCGTGTTCGACGCGGTGGTCCTCGGCGGCCGTGGCGGGGTGTGTTACGAGCTCAACGGCCTGTTC
CGGCGCCTGCTGGCCGAGCTCGGATTCGAGACCGGCGTGTACGCGGCGGCCATCCGGCAGGTCGACGGATCCTTCGGGCC
GGACCTGGAGCACATCTTCACCTTCGTCCGCCTGGACGACGAGGTGCTCCTCGTCGACGTCGGCTTCGTGGGGCCGTCCT
ACCTGGAGCCGCTGCTGCTCGGCACGCAGGAACAGCGGCAGTTCGGCACGTCCTTCCGCATCGTCGGCAGCGAGGGCTAC
CACGTCCTGCAGCGGCGCGGTCAGCGCGGCGACTGGGCCGCCGTGTACCGGTTCCGGCCGGTACCGCGCGACCTCGCTGA
CTGGTCGGCCCCGTCAGAGGAGCTCACCGCCTTCGCCCGGGCGCTGGCGGGAGCGGGGACGCTCGTGCGCGGCCGGGCGA
CCCTCTCCGGGCAGCGGATCCTGATCGGCAAGCGGCTGGTGACCGTCGACAACGGGCACGAGGCCATGCGGGTGCTCACC
GACCCGGCCGAGCACGCCCGCGTGCTCGCCGACATCCTCCGCCGCCCGCCGGCACCCGCCACCGCGCCCACCGGCGACGC
CCGGTGA

Upstream 100 bases:

>100_bases
GCGGCGACCGGCCTCACGCTGCCCGCGATGTTGCTGTTCGACCACGCGGTGCCCCGCGAGGTCGCCGCGTACCTGCTGGA
CCGGCTGGAGGTCGAGACCC

Downstream 100 bases:

>100_bases
CCGCGCCCGAGCCGGCCGAGGTCGAGGCCGAGGTCGAGGCCGAGGCTGAGGCCATGGCCGACGTCGTCGTCGTCGGCTAC
GGGCCGGTCGGCCAGGTAAC

Product: N-acetyltransferase

Products: CoA; an n-acetoxyarylamine [C]

Alternate protein names: AHBA synthase; Rifamycin amide synthase [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MFDVEAYLKALDHRGPADASPETLRRLHHAHLRTVPYDSELNSTRGTDLWKGVDIDADAVFDAVVLGGRGGVCYELNGLF
RRLLAELGFETGVYAAAIRQVDGSFGPDLEHIFTFVRLDDEVLLVDVGFVGPSYLEPLLLGTQEQRQFGTSFRIVGSEGY
HVLQRRGQRGDWAAVYRFRPVPRDLADWSAPSEELTAFARALAGAGTLVRGRATLSGQRILIGKRLVTVDNGHEAMRVLT
DPAEHARVLADILRRPPAPATAPTGDAR

Sequences:

>Translated_268_residues
MFDVEAYLKALDHRGPADASPETLRRLHHAHLRTVPYDSELNSTRGTDLWKGVDIDADAVFDAVVLGGRGGVCYELNGLF
RRLLAELGFETGVYAAAIRQVDGSFGPDLEHIFTFVRLDDEVLLVDVGFVGPSYLEPLLLGTQEQRQFGTSFRIVGSEGY
HVLQRRGQRGDWAAVYRFRPVPRDLADWSAPSEELTAFARALAGAGTLVRGRATLSGQRILIGKRLVTVDNGHEAMRVLT
DPAEHARVLADILRRPPAPATAPTGDAR
>Mature_268_residues
MFDVEAYLKALDHRGPADASPETLRRLHHAHLRTVPYDSELNSTRGTDLWKGVDIDADAVFDAVVLGGRGGVCYELNGLF
RRLLAELGFETGVYAAAIRQVDGSFGPDLEHIFTFVRLDDEVLLVDVGFVGPSYLEPLLLGTQEQRQFGTSFRIVGSEGY
HVLQRRGQRGDWAAVYRFRPVPRDLADWSAPSEELTAFARALAGAGTLVRGRATLSGQRILIGKRLVTVDNGHEAMRVLT
DPAEHARVLADILRRPPAPATAPTGDAR

Specific function: Putatively terminates polyketide biosynthesis by transfer of polyketide acyl chain to the secondary amine on the 3- AHBA starter unit [H]

COG id: COG2162

COG function: function code Q; Arylamine N-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arylamine N-acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001447 [H]

Pfam domain/function: PF00797 Acetyltransf_2 [H]

EC number: 2.3.1.118 [C]

Molecular weight: Translated: 29412; Mature: 29412

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDVEAYLKALDHRGPADASPETLRRLHHAHLRTVPYDSELNSTRGTDLWKGVDIDADAV
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCHHHH
FDAVVLGGRGGVCYELNGLFRRLLAELGFETGVYAAAIRQVDGSFGPDLEHIFTFVRLDD
HHHHEECCCCCEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHEECC
EVLLVDVGFVGPSYLEPLLLGTQEQRQFGTSFRIVGSEGYHVLQRRGQRGDWAAVYRFRP
CEEEEEECCCCHHHHHHHHCCCHHHHHCCCEEEEECCCCHHHHHHCCCCCCEEEEEEECC
VPRDLADWSAPSEELTAFARALAGAGTLVRGRATLSGQRILIGKRLVTVDNGHEAMRVLT
CCCHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEEEEECCCHHHHHHHC
DPAEHARVLADILRRPPAPATAPTGDAR
CCHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MFDVEAYLKALDHRGPADASPETLRRLHHAHLRTVPYDSELNSTRGTDLWKGVDIDADAV
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCHHHH
FDAVVLGGRGGVCYELNGLFRRLLAELGFETGVYAAAIRQVDGSFGPDLEHIFTFVRLDD
HHHHEECCCCCEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHEECC
EVLLVDVGFVGPSYLEPLLLGTQEQRQFGTSFRIVGSEGYHVLQRRGQRGDWAAVYRFRP
CEEEEEECCCCHHHHHHHHCCCHHHHHCCCEEEEECCCCHHHHHHCCCCCCEEEEEEECC
VPRDLADWSAPSEELTAFARALAGAGTLVRGRATLSGQRILIGKRLVTVDNGHEAMRVLT
CCCHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEEEEECCCHHHHHHHC
DPAEHARVLADILRRPPAPATAPTGDAR
CCHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; an n-hydroxyarylamine [C]

Specific reaction: Acetyl-CoA + an n-hydroxyarylamine = CoA + an n-acetoxyarylamine [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9497318 [H]