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The map label for this gene is yngJ [H]

Identifier: 158316493

GI number: 158316493

Start: 5644028

End: 5645167

Strand: Reverse

Name: yngJ [H]

Synonym: Franean1_4728

Alternate gene names: 158316493

Gene position: 5645167-5644028 (Counterclockwise)

Preceding gene: 158316494

Following gene: 158316492

Centisome position: 62.85

GC content: 70.7

Gene sequence:

>1140_bases
ATGCTGTTGGAACTGAGCTCCGACCAGGAGATCTTTCGGGATACCACCGCGAGATTCCTGACCAGTCGGGTGCCGATCAG
CGAGGTCCGGAGTCTCCGGAACCACCCCGCCGGCTTCGATCCCGACTACTGGCGCGAGGGCGCCGAGCTCGGGTGGACGT
CGCTGCTGGTCAGCGAGGAACACGGCGGTGGCTCGGTCGGCGGCGGGGGGCTGGTGGACCTCACCACGATCGCCCATGAG
TTCGGCGTGCACGCCGCGCCGGGACCGCTGGTCCCGACGAACGTGGTCGCCGGGACGCTGAGCACCTTCGGTGGCGAGGC
GCACCGTCCCGTCCTCGAGTCGCTGCTGGCCGGCACATCGGTCGCGGCGTGGTGCTTCGGCCCGGCCGTCGACACCGACG
GCCGCGGCCCCGCGGGCCCGCGCTGCCGGATCGCCGACGGCGAGGTCGTCCTCGACGGCGTCCAGCGTCCCGTCGAGGCG
GCGGGCCAGGCGCACCACATCCTGGTCACGGCCCGGGCCGAGGGTGGGCTCACGCAGATCCTCGTCCCGACCGACACCGC
CGGGGTGTCGATCGAGCCGATGCGCACGGCGGACCTGACCCGCCGTTTCGCGGCGGTGACGTTCGACGGCGTCCGGCTCC
CGGTCGAGGCCCTCGTGGGAGAGTCGGGCGACGCCGACGAGCTCCTCGAGTACCAGCTCCAGCTCGCCGTGGTGATAGGC
AACGCCGAGGCGGTGGGCGCCCTGCAGACCGCCTTCGACATGACGCTGCAATGGGCGTTCGACCGTTACTCGTTCGGTCG
CCCGCTGGCCTCCTACCAGGAGCTCAAGCACCGCTTCGCCGACCAGAAGACGTGGCTGGAAGCCTGCCACGCCGTCAACG
ACGCCGCCGCGGCGGCGGTCGACGACCGGTCGCTCGACGCGAAGGAGCTGGTCAGCGCCGCAAAGGCGTTCATCGGTGAC
TACGGCTCCGAGCTGGTCCAGGACTGCGTGCAGATCCACGGTGGGATCGGCGTTACCTTCGAGCACGATCTGCACCTCTA
CCTGCGCCGGGTAACCGTGAACCGGGCCCTGTACGGCACGCCGGCCGACCATCGCCAACGCATCGCCACCGTGCTCGAGA
ACCGGAAGGAGCGGGTATGA

Upstream 100 bases:

>100_bases
GGGTCGTACCCGGCTGCGGAGCAGAACGTGCGCTTCTTCTTCGGCCGGTAGGACCGACCGGCCCCGGCGGTGCCGCCAGC
GACCTGGAGGAAAACCCGAC

Downstream 100 bases:

>100_bases
CCGACGCCATCGAGGACGTCGAGAGTTTCCGGCTGCGTGCCCGCACCTGGATCCGCGCGAACCTCCGCCCGCTGGAGCCA
CACGAGACACTCGCGCCCAC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MLLELSSDQEIFRDTTARFLTSRVPISEVRSLRNHPAGFDPDYWREGAELGWTSLLVSEEHGGGSVGGGGLVDLTTIAHE
FGVHAAPGPLVPTNVVAGTLSTFGGEAHRPVLESLLAGTSVAAWCFGPAVDTDGRGPAGPRCRIADGEVVLDGVQRPVEA
AGQAHHILVTARAEGGLTQILVPTDTAGVSIEPMRTADLTRRFAAVTFDGVRLPVEALVGESGDADELLEYQLQLAVVIG
NAEAVGALQTAFDMTLQWAFDRYSFGRPLASYQELKHRFADQKTWLEACHAVNDAAAAAVDDRSLDAKELVSAAKAFIGD
YGSELVQDCVQIHGGIGVTFEHDLHLYLRRVTVNRALYGTPADHRQRIATVLENRKERV

Sequences:

>Translated_379_residues
MLLELSSDQEIFRDTTARFLTSRVPISEVRSLRNHPAGFDPDYWREGAELGWTSLLVSEEHGGGSVGGGGLVDLTTIAHE
FGVHAAPGPLVPTNVVAGTLSTFGGEAHRPVLESLLAGTSVAAWCFGPAVDTDGRGPAGPRCRIADGEVVLDGVQRPVEA
AGQAHHILVTARAEGGLTQILVPTDTAGVSIEPMRTADLTRRFAAVTFDGVRLPVEALVGESGDADELLEYQLQLAVVIG
NAEAVGALQTAFDMTLQWAFDRYSFGRPLASYQELKHRFADQKTWLEACHAVNDAAAAAVDDRSLDAKELVSAAKAFIGD
YGSELVQDCVQIHGGIGVTFEHDLHLYLRRVTVNRALYGTPADHRQRIATVLENRKERV
>Mature_379_residues
MLLELSSDQEIFRDTTARFLTSRVPISEVRSLRNHPAGFDPDYWREGAELGWTSLLVSEEHGGGSVGGGGLVDLTTIAHE
FGVHAAPGPLVPTNVVAGTLSTFGGEAHRPVLESLLAGTSVAAWCFGPAVDTDGRGPAGPRCRIADGEVVLDGVQRPVEA
AGQAHHILVTARAEGGLTQILVPTDTAGVSIEPMRTADLTRRFAAVTFDGVRLPVEALVGESGDADELLEYQLQLAVVIG
NAEAVGALQTAFDMTLQWAFDRYSFGRPLASYQELKHRFADQKTWLEACHAVNDAAAAAVDDRSLDAKELVSAAKAFIGD
YGSELVQDCVQIHGGIGVTFEHDLHLYLRRVTVNRALYGTPADHRQRIATVLENRKERV

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=346, Percent_Identity=25.7225433526012, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4557231, Length=385, Percent_Identity=23.3766233766234, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI187960098, Length=385, Percent_Identity=23.3766233766234, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4557233, Length=287, Percent_Identity=22.9965156794425, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4501859, Length=227, Percent_Identity=26.431718061674, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4501857, Length=360, Percent_Identity=21.9444444444444, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1786223, Length=318, Percent_Identity=21.6981132075472, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081958, Length=372, Percent_Identity=23.1182795698925, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=392, Percent_Identity=23.469387755102, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17569725, Length=387, Percent_Identity=22.4806201550388, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=389, Percent_Identity=23.3933161953728, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=345, Percent_Identity=22.6086956521739, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17570075, Length=398, Percent_Identity=22.3618090452261, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646207, Length=380, Percent_Identity=22.3684210526316, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356377, Length=388, Percent_Identity=22.9381443298969, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 40681; Mature: 40681

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLELSSDQEIFRDTTARFLTSRVPISEVRSLRNHPAGFDPDYWREGAELGWTSLLVSEE
CEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEEEEC
HGGGSVGGGGLVDLTTIAHEFGVHAAPGPLVPTNVVAGTLSTFGGEAHRPVLESLLAGTS
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCC
VAAWCFGPAVDTDGRGPAGPRCRIADGEVVLDGVQRPVEAAGQAHHILVTARAEGGLTQI
HHHHEECCCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHCCCCEEEEEEEECCCCEEEE
LVPTDTAGVSIEPMRTADLTRRFAAVTFDGVRLPVEALVGESGDADELLEYQLQLAVVIG
EEECCCCCCEECCCHHHHHHHHHHHEEECCCCCCHHHHCCCCCCHHHHHHHHEEEEEEEC
NAEAVGALQTAFDMTLQWAFDRYSFGRPLASYQELKHRFADQKTWLEACHAVNDAAAAAV
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
DDRSLDAKELVSAAKAFIGDYGSELVQDCVQIHGGIGVTFEHDLHLYLRRVTVNRALYGT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHCCCC
PADHRQRIATVLENRKERV
CHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLELSSDQEIFRDTTARFLTSRVPISEVRSLRNHPAGFDPDYWREGAELGWTSLLVSEE
CEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEEEEC
HGGGSVGGGGLVDLTTIAHEFGVHAAPGPLVPTNVVAGTLSTFGGEAHRPVLESLLAGTS
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCC
VAAWCFGPAVDTDGRGPAGPRCRIADGEVVLDGVQRPVEAAGQAHHILVTARAEGGLTQI
HHHHEECCCCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHCCCCEEEEEEEECCCCEEEE
LVPTDTAGVSIEPMRTADLTRRFAAVTFDGVRLPVEALVGESGDADELLEYQLQLAVVIG
EEECCCCCCEECCCHHHHHHHHHHHEEECCCCCCHHHHCCCCCCHHHHHHHHEEEEEEEC
NAEAVGALQTAFDMTLQWAFDRYSFGRPLASYQELKHRFADQKTWLEACHAVNDAAAAAV
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
DDRSLDAKELVSAAKAFIGDYGSELVQDCVQIHGGIGVTFEHDLHLYLRRVTVNRALYGT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHCCCC
PADHRQRIATVLENRKERV
CHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]