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The map label for this gene is acdA [H]

Identifier: 158316492

GI number: 158316492

Start: 5642760

End: 5644031

Strand: Reverse

Name: acdA [H]

Synonym: Franean1_4727

Alternate gene names: 158316492

Gene position: 5644031-5642760 (Counterclockwise)

Preceding gene: 158316493

Following gene: 158316490

Centisome position: 62.84

GC content: 70.83

Gene sequence:

>1272_bases
ATGACCGACGCCATCGAGGACGTCGAGAGTTTCCGGCTGCGTGCCCGCACCTGGATCCGCGCGAACCTCCGCCCGCTGGA
GCCACACGAGACACTCGCGCCCACCCTCGCGTTACCGGTCCAGACCGAGGAGGAGGAACACGCCGCGCTCGCCCGGGAGC
GTGAGCTCCAGCGCATGATCTTCGACGCCGGCCTCGCCGGGATCGGCTTCCCCCGGGAGTACGGCGGGCAGGGCCTGACG
ACGGACCATCAGCGCGCGTTCAACGCCGAGATCGTGGGCTACGAATACCCGGCGCGGCTGCAGGCGCCGACGTTCTCGCC
CTGCGGTGCCGTGCTGCTGGACTTCGGCACCGAGGAGCAGAAGCGCCGGCACATCCCCGCCATTCTCAAGGGCGAGGAGA
TCTGGATGCAGCTGCTGTCCGAGCCCAGCGGCGGGTCGGACGTCGCGGCCGCCCTCACCAGCGCCGTCCGTGACGGCGAC
GACTGGATCCTGAACGGCTCGAAGGTCTGGACGACCGGTGCCTCGACCGCCGACTGGGGCCTGTGCCTGGCCCGGACGAA
CTGGGACGTCCCGAAGCACCGCGGCCTGACCGTGTTCATCCTGCCGATCCACCAGCCGGGCATCGAGGTGCACCGCATCG
AGATGCTGAACGGCTCGACCGAGTTCTGCCAGGAGTTCCTCACCGACGTCCGGGTCCCGGACAGCGACCGTATCGGCGAC
GTCGACGGCGGCTGGACGGTCGGCACCCGGTGGATGTTCCACGAGCGGATGCTCTTCAACTCGCCGTTCGTCAGCATCCC
GGTGGGAACCTCGCCCGGCGAGGTCGGTGCCGCCTCCATCGTCAACGTCGCCCGGGACGCCGGGCGGTTCGACGACCGCT
GCGTCCGGGACCTCCTCGGCGAGGCCCACATGCTGGAGCTCGTCGGCCAGACGCTGCGGCGCCGGATCGGCCGCGGTGTC
GCCGCGGGCCGGATCTCCGAGCAGTCCGCCGCGATCACCCGCCTGTTCGCGGGTGTCTCCTCCGCGCGGAAGGCCACCAT
CGCGTTCGAGATCGCGGGCCCCGCGGGCGCGGCCTGGACGGCGGACGACGGTGCGGCGGCGAACTGCGGCGACGACTTCC
TGATGCGGCAGACGTCGTGCATCGGTGGCGGCACCACGGAGATGGCCCGTAACGTGATCAGTGAGCGGGTGCTCGGCATG
CCCCGCGAGCGCACACCCGACCGTGACCGACCCTTCCGCGACGTACCACGTAGCGCATCGAACCGCGCCTGA

Upstream 100 bases:

>100_bases
TCTACCTGCGCCGGGTAACCGTGAACCGGGCCCTGTACGGCACGCCGGCCGACCATCGCCAACGCATCGCCACCGTGCTC
GAGAACCGGAAGGAGCGGGT

Downstream 100 bases:

>100_bases
CCGGAATCCCGGCCGGAGCGGTTCGCCAAGCGCTTCACGCCTATGGGACTCCAAATTCGGGTTCGGCACCTCGGCTGACG
GAACCGCCACGCCGCCTACA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTDAIEDVESFRLRARTWIRANLRPLEPHETLAPTLALPVQTEEEEHAALARERELQRMIFDAGLAGIGFPREYGGQGLT
TDHQRAFNAEIVGYEYPARLQAPTFSPCGAVLLDFGTEEQKRRHIPAILKGEEIWMQLLSEPSGGSDVAAALTSAVRDGD
DWILNGSKVWTTGASTADWGLCLARTNWDVPKHRGLTVFILPIHQPGIEVHRIEMLNGSTEFCQEFLTDVRVPDSDRIGD
VDGGWTVGTRWMFHERMLFNSPFVSIPVGTSPGEVGAASIVNVARDAGRFDDRCVRDLLGEAHMLELVGQTLRRRIGRGV
AAGRISEQSAAITRLFAGVSSARKATIAFEIAGPAGAAWTADDGAAANCGDDFLMRQTSCIGGGTTEMARNVISERVLGM
PRERTPDRDRPFRDVPRSASNRA

Sequences:

>Translated_423_residues
MTDAIEDVESFRLRARTWIRANLRPLEPHETLAPTLALPVQTEEEEHAALARERELQRMIFDAGLAGIGFPREYGGQGLT
TDHQRAFNAEIVGYEYPARLQAPTFSPCGAVLLDFGTEEQKRRHIPAILKGEEIWMQLLSEPSGGSDVAAALTSAVRDGD
DWILNGSKVWTTGASTADWGLCLARTNWDVPKHRGLTVFILPIHQPGIEVHRIEMLNGSTEFCQEFLTDVRVPDSDRIGD
VDGGWTVGTRWMFHERMLFNSPFVSIPVGTSPGEVGAASIVNVARDAGRFDDRCVRDLLGEAHMLELVGQTLRRRIGRGV
AAGRISEQSAAITRLFAGVSSARKATIAFEIAGPAGAAWTADDGAAANCGDDFLMRQTSCIGGGTTEMARNVISERVLGM
PRERTPDRDRPFRDVPRSASNRA
>Mature_422_residues
TDAIEDVESFRLRARTWIRANLRPLEPHETLAPTLALPVQTEEEEHAALARERELQRMIFDAGLAGIGFPREYGGQGLTT
DHQRAFNAEIVGYEYPARLQAPTFSPCGAVLLDFGTEEQKRRHIPAILKGEEIWMQLLSEPSGGSDVAAALTSAVRDGDD
WILNGSKVWTTGASTADWGLCLARTNWDVPKHRGLTVFILPIHQPGIEVHRIEMLNGSTEFCQEFLTDVRVPDSDRIGDV
DGGWTVGTRWMFHERMLFNSPFVSIPVGTSPGEVGAASIVNVARDAGRFDDRCVRDLLGEAHMLELVGQTLRRRIGRGVA
AGRISEQSAAITRLFAGVSSARKATIAFEIAGPAGAAWTADDGAAANCGDDFLMRQTSCIGGGTTEMARNVISERVLGMP
RERTPDRDRPFRDVPRSASNRA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=217, Percent_Identity=30.4147465437788, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI226958414, Length=219, Percent_Identity=29.6803652968037, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=23.6702127659574, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4557231, Length=312, Percent_Identity=26.6025641025641, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI187960098, Length=312, Percent_Identity=26.6025641025641, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4501859, Length=217, Percent_Identity=29.4930875576037, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI7656849, Length=201, Percent_Identity=29.3532338308458, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4557233, Length=190, Percent_Identity=29.4736842105263, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI4557235, Length=301, Percent_Identity=28.2392026578073, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI76496475, Length=301, Percent_Identity=28.2392026578073, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI21361497, Length=198, Percent_Identity=29.2929292929293, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87081958, Length=212, Percent_Identity=29.2452830188679, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786223, Length=203, Percent_Identity=28.0788177339901, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17534899, Length=201, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=237, Percent_Identity=30.8016877637131, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=197, Percent_Identity=33.502538071066, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=363, Percent_Identity=26.9972451790634, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=275, Percent_Identity=26.9090909090909, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17506239, Length=219, Percent_Identity=29.2237442922374, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17570075, Length=300, Percent_Identity=28.3333333333333, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=219, Percent_Identity=26.9406392694064, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=205, Percent_Identity=30.2439024390244, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32563615, Length=212, Percent_Identity=28.7735849056604, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=256, Percent_Identity=28.125, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646207, Length=206, Percent_Identity=32.0388349514563, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21356377, Length=213, Percent_Identity=30.9859154929577, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21355753, Length=305, Percent_Identity=27.2131147540984, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24666513, Length=223, Percent_Identity=27.8026905829596, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24660351, Length=185, Percent_Identity=31.3513513513514, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281363737, Length=373, Percent_Identity=23.5924932975871, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 46318; Mature: 46187

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAIEDVESFRLRARTWIRANLRPLEPHETLAPTLALPVQTEEEEHAALARERELQRMI
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHH
FDAGLAGIGFPREYGGQGLTTDHQRAFNAEIVGYEYPARLQAPTFSPCGAVLLDFGTEEQ
HHHCCCCCCCCHHHCCCCCCCHHHHHCCCEEECCCCCCCCCCCCCCCCHHHHCCCCCCHH
KRRHIPAILKGEEIWMQLLSEPSGGSDVAAALTSAVRDGDDWILNGSKVWTTGASTADWG
HHHCCCCEECHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCCCC
LCLARTNWDVPKHRGLTVFILPIHQPGIEVHRIEMLNGSTEFCQEFLTDVRVPDSDRIGD
EEEEECCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCC
VDGGWTVGTRWMFHERMLFNSPFVSIPVGTSPGEVGAASIVNVARDAGRFDDRCVRDLLG
CCCCCEECCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHC
EAHMLELVGQTLRRRIGRGVAAGRISEQSAAITRLFAGVSSARKATIAFEIAGPAGAAWT
HHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEE
ADDGAAANCGDDFLMRQTSCIGGGTTEMARNVISERVLGMPRERTPDRDRPFRDVPRSAS
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCC
NRA
CCC
>Mature Secondary Structure 
TDAIEDVESFRLRARTWIRANLRPLEPHETLAPTLALPVQTEEEEHAALARERELQRMI
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHH
FDAGLAGIGFPREYGGQGLTTDHQRAFNAEIVGYEYPARLQAPTFSPCGAVLLDFGTEEQ
HHHCCCCCCCCHHHCCCCCCCHHHHHCCCEEECCCCCCCCCCCCCCCCHHHHCCCCCCHH
KRRHIPAILKGEEIWMQLLSEPSGGSDVAAALTSAVRDGDDWILNGSKVWTTGASTADWG
HHHCCCCEECHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCCCC
LCLARTNWDVPKHRGLTVFILPIHQPGIEVHRIEMLNGSTEFCQEFLTDVRVPDSDRIGD
EEEEECCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCC
VDGGWTVGTRWMFHERMLFNSPFVSIPVGTSPGEVGAASIVNVARDAGRFDDRCVRDLLG
CCCCCEECCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHC
EAHMLELVGQTLRRRIGRGVAAGRISEQSAAITRLFAGVSSARKATIAFEIAGPAGAAWT
HHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEE
ADDGAAANCGDDFLMRQTSCIGGGTTEMARNVISERVLGMPRERTPDRDRPFRDVPRSAS
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCC
NRA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]