| Definition | Frankia sp. EAN1pec chromosome, complete genome. |
|---|---|
| Accession | NC_009921 |
| Length | 8,982,042 |
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The map label for this gene is fabG [H]
Identifier: 158316488
GI number: 158316488
Start: 5637928
End: 5638662
Strand: Reverse
Name: fabG [H]
Synonym: Franean1_4723
Alternate gene names: 158316488
Gene position: 5638662-5637928 (Counterclockwise)
Preceding gene: 158316489
Following gene: 158316487
Centisome position: 62.78
GC content: 62.04
Gene sequence:
>735_bases ATGCTTGACGGGAAGGTGGCGGTGATAACCGGCGCTGGATCGGGGATAGCGAAGGCGTCTACAAAGCTCTTCGTGCAGGA GGGTGCCAAGGTGGTGGCCGTCGATATAAGTGGTGCGGAGAAGGAGACTGCGGCCGAAGTCGGCGAAAATGTCCTTCCCT TCCACTGCGACGTCTCCGACGAGACGGGCGTTGCTGCGATGTTCGAGGCCACTATCAAGGAGTTCGGACGCGTCGATGCC GTGCTGAACGTGGCCGGTACCCACGGTACCCGGCCACCTGAGGTCGTCGCCGTCGCCGAGTTCGAGAAGATGACCCAGGT GAATCTGCGTGGCGTGCTCATTATGACCGAACATGCGATTCCAGCGATGCTCCGCTCAGGCGGCGGCAGCATCGTCAACT TCTCCTCGATCTCAGCGGTCAACGTCCAGAGCCGGACGTCAATCATGTATGCTGCCGCGAAAGCCGGCACCCATGCCCTC ACCAAGGCGGTGGCCGTCGAGTACGGTCCCATGGGCATCCGGGCAAACGTCATCGCACCTGGATTTACGCTCACCGATAT CATGAAAGGGCCGCCTGAGTTGCTGCGCGAGATGAGCTCGAAGGCTGCACTCAAACGGGGCGGTCAACCGCGGGAGCTGG CCGAGGTAGCGGCTTTTCTGGCCTCGGACCGCGCCTCCTTCGTGACCGGAGTCATCATTCCAGTCGATGGTGGCTGGTCG GCGCGACTGGCCTAG
Upstream 100 bases:
>100_bases GAGAACGACGGGCCGTTCATGGCCGCGTACTTGAGTCGTTGTGTGCTGGTGACGAGGGTACCGGTCCCGATGCACCGGTC TACGGAGGTGAGTAATGGGC
Downstream 100 bases:
>100_bases TGAACCGAGAGGAGGACTCCGTCTTCCTCTCGGTTCGAGGGTTCGGGTTTCCGGACGCTTCGGCGGAACGACCTGCTGTC AGCCGGTGGATGACAGACAA
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 244; Mature: 244
Protein sequence:
>244_residues MLDGKVAVITGAGSGIAKASTKLFVQEGAKVVAVDISGAEKETAAEVGENVLPFHCDVSDETGVAAMFEATIKEFGRVDA VLNVAGTHGTRPPEVVAVAEFEKMTQVNLRGVLIMTEHAIPAMLRSGGGSIVNFSSISAVNVQSRTSIMYAAAKAGTHAL TKAVAVEYGPMGIRANVIAPGFTLTDIMKGPPELLREMSSKAALKRGGQPRELAEVAAFLASDRASFVTGVIIPVDGGWS ARLA
Sequences:
>Translated_244_residues MLDGKVAVITGAGSGIAKASTKLFVQEGAKVVAVDISGAEKETAAEVGENVLPFHCDVSDETGVAAMFEATIKEFGRVDA VLNVAGTHGTRPPEVVAVAEFEKMTQVNLRGVLIMTEHAIPAMLRSGGGSIVNFSSISAVNVQSRTSIMYAAAKAGTHAL TKAVAVEYGPMGIRANVIAPGFTLTDIMKGPPELLREMSSKAALKRGGQPRELAEVAAFLASDRASFVTGVIIPVDGGWS ARLA >Mature_244_residues MLDGKVAVITGAGSGIAKASTKLFVQEGAKVVAVDISGAEKETAAEVGENVLPFHCDVSDETGVAAMFEATIKEFGRVDA VLNVAGTHGTRPPEVVAVAEFEKMTQVNLRGVLIMTEHAIPAMLRSGGGSIVNFSSISAVNVQSRTSIMYAAAKAGTHAL TKAVAVEYGPMGIRANVIAPGFTLTDIMKGPPELLREMSSKAALKRGGQPRELAEVAAFLASDRASFVTGVIIPVDGGWS ARLA
Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI59889578, Length=229, Percent_Identity=35.3711790393013, Blast_Score=120, Evalue=8e-28, Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=30.1587301587302, Blast_Score=114, Evalue=6e-26, Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=33.75, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=31.7269076305221, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=33.596837944664, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=32.4110671936759, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=28.6290322580645, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=28.4046692607004, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI4503301, Length=251, Percent_Identity=32.6693227091633, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI31542939, Length=199, Percent_Identity=31.1557788944724, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI4758504, Length=250, Percent_Identity=30.4, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=28.2945736434109, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=29.4354838709677, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=30.0578034682081, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=25.2918287937743, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI83715985, Length=249, Percent_Identity=28.1124497991968, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI4504505, Length=258, Percent_Identity=28.6821705426357, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI20149619, Length=199, Percent_Identity=30.1507537688442, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=33.7448559670782, Blast_Score=130, Evalue=6e-32, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=33.4630350194552, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=31.1475409836066, Blast_Score=107, Evalue=1e-24, Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=28.3400809716599, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=31.4285714285714, Blast_Score=103, Evalue=8e-24, Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=29.1497975708502, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=31.8548387096774, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=29.8804780876494, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=28.0487804878049, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=31.2757201646091, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=28.740157480315, Blast_Score=81, Evalue=5e-17, Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=27.9166666666667, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=25.6983240223464, Blast_Score=72, Evalue=4e-14, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=29.4820717131474, Blast_Score=114, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=35.6275303643725, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=30.3643724696356, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=30.6513409961686, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=31.6981132075472, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=31.5384615384615, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=31.3008130081301, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=32.183908045977, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=31.6981132075472, Blast_Score=104, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=31.1538461538462, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=30.1526717557252, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=31.8007662835249, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=30.5970149253731, Blast_Score=97, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=30.1526717557252, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=30.6201550387597, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=30.5660377358491, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=30.188679245283, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=31.3725490196078, Blast_Score=93, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=29.3893129770992, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=30.1526717557252, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=29.4339622641509, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=30.0380228136882, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=29.6153846153846, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=30, Blast_Score=89, Evalue=1e-18, Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=29.7959183673469, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=27.5862068965517, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=29.2490118577075, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17561272, Length=254, Percent_Identity=32.6771653543307, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=27.3809523809524, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI71982365, Length=248, Percent_Identity=26.2096774193548, Blast_Score=71, Evalue=5e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=30.1960784313725, Blast_Score=86, Evalue=5e-18, Organism=Saccharomyces cerevisiae, GI6322861, Length=208, Percent_Identity=29.8076923076923, Blast_Score=63, Evalue=4e-11, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=38.4615384615385, Blast_Score=133, Evalue=1e-31, Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=32.520325203252, Blast_Score=124, Evalue=8e-29, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=32.9365079365079, Blast_Score=120, Evalue=6e-28, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=32.9365079365079, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=31.2, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=32.9457364341085, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI24643142, Length=251, Percent_Identity=32.2709163346614, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=31.7460317460317, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI18859837, Length=257, Percent_Identity=29.5719844357977, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24665243, Length=194, Percent_Identity=31.9587628865979, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI221331218, Length=194, Percent_Identity=31.9587628865979, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=26.3779527559055, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24665247, Length=195, Percent_Identity=32.3076923076923, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI221331216, Length=195, Percent_Identity=32.3076923076923, Blast_Score=80, Evalue=9e-16, Organism=Drosophila melanogaster, GI24641232, Length=210, Percent_Identity=29.5238095238095, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI281364892, Length=217, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI281364494, Length=208, Percent_Identity=29.8076923076923, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI116007236, Length=210, Percent_Identity=30, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24665264, Length=200, Percent_Identity=30, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI116007238, Length=210, Percent_Identity=27.1428571428571, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25251; Mature: 25251
Theoretical pI: Translated: 6.53; Mature: 6.53
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLDGKVAVITGAGSGIAKASTKLFVQEGAKVVAVDISGAEKETAAEVGENVLPFHCDVSD CCCCEEEEEEECCCCCHHHHHHHEEECCCEEEEEEECCCCHHHHHHHCCCCCEEEECCCC ETGVAAMFEATIKEFGRVDAVLNVAGTHGTRPPEVVAVAEFEKMTQVNLRGVLIMTEHAI CCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEHHHHHHHCCCEEEEEEECCHH PAMLRSGGGSIVNFSSISAVNVQSRTSIMYAAAKAGTHALTKAVAVEYGPMGIRANVIAP HHHHHCCCCCEEEECCEEEEEECCHHEEEEEHHHCCHHHHHHHHHEEECCCCEEEEEEEC GFTLTDIMKGPPELLREMSSKAALKRGGQPRELAEVAAFLASDRASFVTGVIIPVDGGWS CCCHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCC ARLA CCCC >Mature Secondary Structure MLDGKVAVITGAGSGIAKASTKLFVQEGAKVVAVDISGAEKETAAEVGENVLPFHCDVSD CCCCEEEEEEECCCCCHHHHHHHEEECCCEEEEEEECCCCHHHHHHHCCCCCEEEECCCC ETGVAAMFEATIKEFGRVDAVLNVAGTHGTRPPEVVAVAEFEKMTQVNLRGVLIMTEHAI CCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEHHHHHHHCCCEEEEEEECCHH PAMLRSGGGSIVNFSSISAVNVQSRTSIMYAAAKAGTHALTKAVAVEYGPMGIRANVIAP HHHHHCCCCCEEEECCEEEEEECCHHEEEEEHHHCCHHHHHHHHHEEECCCCEEEEEEEC GFTLTDIMKGPPELLREMSSKAALKRGGQPRELAEVAAFLASDRASFVTGVIIPVDGGWS CCCHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCC ARLA CCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]