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The map label for this gene is coxS [H]

Identifier: 158316475

GI number: 158316475

Start: 5625405

End: 5625902

Strand: Reverse

Name: coxS [H]

Synonym: Franean1_4710

Alternate gene names: 158316475

Gene position: 5625902-5625405 (Counterclockwise)

Preceding gene: 158316476

Following gene: 158316474

Centisome position: 62.63

GC content: 68.67

Gene sequence:

>498_bases
ATGACCGAGATGGATGTGAACCTGATCGTGAACGGCGAACGCTGTCGCGCCCGGGTCGAGCCGCGCAAGACTCTCGCCGA
CCTGCTGCGGGAGGACCTCGGGCTGACCGGCACCCACCTGGGGTGCGAGCACGGGGTCTGCGGGTCGTGCACAGTGCTGC
TCGACGGCCTGGCTGTCCGGTCCTGCCTGATGTTCGGGGTGCAGGCGGACGGAAGCGAGGTGACCAGCGTCGAGGGGCTG
GCGGGCGATCCGGAATCGCTCAGCCTGGTGCAGCGCGCCTTCCAGGAGACACATGGGTTGCAGTGCGGTTTCTGCACCCC
CGGGTTCGTCATATCGGTCACGGCTTTCCTGGAGGATGTGCCGGATCCGACCGACGAGCAGATCCGGGACGGCCTGAGCG
GGAACCTCTGCCGCTGCACCGGCTACCAGGGCATTGTGCACGCCGTCCGGCTTGCGGCGCGGCTGCGCCGCGAGGAACGC
GCCGAAACCTCGGGGTAG

Upstream 100 bases:

>100_bases
AGATGACTGCGCGAGCACTTGGCCGGGCCCTCGCGGAGGCCCAGGGACAGGAACGGAACCCAGGCCAGAGCCAGGCCCAG
GCCGAGGCGGGAGGCACCGC

Downstream 100 bases:

>100_bases
GTGTGCGGGAGCTCGCTGAGCAGGTGCGCGGATGGCGGTCAGCCGGGATGGTGGCACGCCGACCGCAGTTTCCGCCGGGA
CCGCATCGATTCATGGCACC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTEMDVNLIVNGERCRARVEPRKTLADLLREDLGLTGTHLGCEHGVCGSCTVLLDGLAVRSCLMFGVQADGSEVTSVEGL
AGDPESLSLVQRAFQETHGLQCGFCTPGFVISVTAFLEDVPDPTDEQIRDGLSGNLCRCTGYQGIVHAVRLAARLRREER
AETSG

Sequences:

>Translated_165_residues
MTEMDVNLIVNGERCRARVEPRKTLADLLREDLGLTGTHLGCEHGVCGSCTVLLDGLAVRSCLMFGVQADGSEVTSVEGL
AGDPESLSLVQRAFQETHGLQCGFCTPGFVISVTAFLEDVPDPTDEQIRDGLSGNLCRCTGYQGIVHAVRLAARLRREER
AETSG
>Mature_164_residues
TEMDVNLIVNGERCRARVEPRKTLADLLREDLGLTGTHLGCEHGVCGSCTVLLDGLAVRSCLMFGVQADGSEVTSVEGLA
GDPESLSLVQRAFQETHGLQCGFCTPGFVISVTAFLEDVPDPTDEQIRDGLSGNLCRCTGYQGIVHAVRLAARLRREERA
ETSG

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=165, Percent_Identity=40, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI71773480, Length=90, Percent_Identity=44.4444444444444, Blast_Score=90, Evalue=9e-19,
Organism=Escherichia coli, GI1786480, Length=165, Percent_Identity=41.2121212121212, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI1789232, Length=148, Percent_Identity=43.9189189189189, Blast_Score=116, Evalue=6e-28,
Organism=Escherichia coli, GI1789246, Length=159, Percent_Identity=27.0440251572327, Blast_Score=60, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17540638, Length=154, Percent_Identity=44.8051948051948, Blast_Score=129, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17539860, Length=151, Percent_Identity=45.6953642384106, Blast_Score=125, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI32566215, Length=151, Percent_Identity=43.7086092715232, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17737937, Length=161, Percent_Identity=38.5093167701863, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24647193, Length=138, Percent_Identity=35.5072463768116, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647199, Length=135, Percent_Identity=35.5555555555556, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24647197, Length=161, Percent_Identity=34.7826086956522, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24647195, Length=161, Percent_Identity=34.7826086956522, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24647201, Length=169, Percent_Identity=31.9526627218935, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17723; Mature: 17592

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
5.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEMDVNLIVNGERCRARVEPRKTLADLLREDLGLTGTHLGCEHGVCGSCTVLLDGLAVR
CCCCCEEEEEECHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SCLMFGVQADGSEVTSVEGLAGDPESLSLVQRAFQETHGLQCGFCTPGFVISVTAFLEDV
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHC
PDPTDEQIRDGLSGNLCRCTGYQGIVHAVRLAARLRREERAETSG
CCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TEMDVNLIVNGERCRARVEPRKTLADLLREDLGLTGTHLGCEHGVCGSCTVLLDGLAVR
CCCCEEEEEECHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SCLMFGVQADGSEVTSVEGLAGDPESLSLVQRAFQETHGLQCGFCTPGFVISVTAFLEDV
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHC
PDPTDEQIRDGLSGNLCRCTGYQGIVHAVRLAARLRREERAETSG
CCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]