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The map label for this gene is yngI [H]

Identifier: 158316400

GI number: 158316400

Start: 5526992

End: 5528665

Strand: Reverse

Name: yngI [H]

Synonym: Franean1_4634

Alternate gene names: 158316400

Gene position: 5528665-5526992 (Counterclockwise)

Preceding gene: 158316401

Following gene: 158316399

Centisome position: 61.55

GC content: 68.4

Gene sequence:

>1674_bases
GTGAACGAGCGCCCGGCGGCAGACTTAGCCGAAGCACTGGCCGAGCTCCGGACGCGGACCGTGTGGCAGATGCTCGTCGC
GTCGGCGGAGCGGGTCCCGGACCGCGCCGCGCTTGTCGCGGCTGACGACGGTGGGAACGTGCAACGGCTGACCTATGCCA
CGTTGGTCGAGCGGGTGCGGGCGTTGTCCGCCGGCCTGGCCAGTATCGGTGTCCGGCGCGGGGACCGTGTCGTGTTGTGG
CTGACGAACACGCCGGAGTGGGTCGTCTCGCATTTCGCCTGCATGCGGCTTGGTGCGGTGACGGTGCCTGTCAACACTTT
CCTGAAGCCGGCCGAGGTCTCCTACGTCATTACCCAGTCCGGTGCCCGTCACGTGATCCTGCTCGACGGCTTCCGGGCTC
TGCGGATGCCCGCGATGCTCGCGGAGATCTGCCCGGAGTTCGCGACCGCGGACCTGCCCGGGCACCTGCTCAGCGCCGGG
ATCCCGGACCTGCGCAACGTGGTGATTTTCCACCGCGGTGGCGGTCGGCACGGCGGGGCCTTTGACCTCGGTGCGCTGGA
GGCGCTGGGCCGTGACCCGAGTGCCGCGGATGCCCGGGGGCTTGCCGATCGCCTGGAGCGGCAGGTATTGGGCAGCGACC
TGGCGATGGTGAAGTACACGTCCGGCAGCACCGGGTTCCCGAAGGGGGTGATGCTTGAACAAGGCGGCATCGTCGCCAAC
GCGGCGCTGCACTCCCGACGTATCGGGATCGGCGGCTCGGACGTGTTCTTCAGCATGATGCCGTTCTTCCATGCCGGCGG
CAGCATCTGGGGCCTCATGACGATGCTGGTGAACGGCGGCACGCTCGTGTTCACCGAGGCTTTCAACGCCCGCCTCGGCG
CGGAGCTGATCGAGTCCGAGCGGGCCACCGTGATGTTCGGGGTGATTCCTGCGGAGGTCGTGCAGGCGGCGATCGAGGAC
GGGCGCGATCTGTCGTCGCTGCGGATCGCGGCTGTGCCGAACGAGGATGCCCGTCGGGTGATGCCCAATGTCACGTTCAC
GTTCGTCCCGTTCGGTCTTACGGAGACGTACGGGCCGGCGTCGGTGACGGCTCCGGATGATCCGCCCGACAAGCGGCGCA
CGACGGGGGGCCGTCCCCTACCGGGTAACGAGGTCCGCGTCGTCGACCCTGCGACCGGCCTCGACGTCCCACCTGGGGCT
GTCGGTGAGGCATGGGTGCGCGGCAACGTCATGCGGGGCTACTGGAACAAGCCCGAGGAGAACGCCCGGGTTCTCGATGC
CGACGGCTGGCTGCACAGCGAGGACCTCGTCTCCATGGACGCCGACGGCTACATCACCTATGCGGGTCGGCTGAAGCTGA
TGCTGAAGGTCGGCGGTGAGAACGTCTCGGTGGAGGAGGTCGAGAAGGTCGTCGCCAGCCACGACGCAGTGGCCTACTGC
GGAGTAGTCGGCGTGCCCGACCGGCGCAGGGGCGAGGTGGTGCGGGCTTACGTCGTCGTGCGCCCCGGCCACTGCCTCGA
CGCCGACATCTTGCGCTCGTGGCTCAAGACGCGTCTCGCCCGGTTCAAAGTTCCCAGGGACATCGTGTTTCTCGACGAGC
TTCCGCGGTTGGCCAACGGGAAGCTCGACCGGGTCGGCCTGGCCGGACGGGCCAAGGAAGAGGTGACGGCGTGA

Upstream 100 bases:

>100_bases
GCGTGACGGCGATGGCGGGCTGGCCACCGTTCTCGCCCGGGTATCCGTACCGGATCGGACAGCCGACGGCGGCGTGGCGG
GCGGCGGCGAGGGCGGCCCG

Downstream 100 bases:

>100_bases
CCGGCGTGACCGATGTGACCGACGCGGATGTCTTCGCCGCGTTCCCCGCGGTGCTGATCGACCGCGACAACATCGAGCAT
TACCGCGGGCTGCTCCAGCA

Product: AMP-dependent synthetase and ligase

Products: AMP; diphosphate; acyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MNERPAADLAEALAELRTRTVWQMLVASAERVPDRAALVAADDGGNVQRLTYATLVERVRALSAGLASIGVRRGDRVVLW
LTNTPEWVVSHFACMRLGAVTVPVNTFLKPAEVSYVITQSGARHVILLDGFRALRMPAMLAEICPEFATADLPGHLLSAG
IPDLRNVVIFHRGGGRHGGAFDLGALEALGRDPSAADARGLADRLERQVLGSDLAMVKYTSGSTGFPKGVMLEQGGIVAN
AALHSRRIGIGGSDVFFSMMPFFHAGGSIWGLMTMLVNGGTLVFTEAFNARLGAELIESERATVMFGVIPAEVVQAAIED
GRDLSSLRIAAVPNEDARRVMPNVTFTFVPFGLTETYGPASVTAPDDPPDKRRTTGGRPLPGNEVRVVDPATGLDVPPGA
VGEAWVRGNVMRGYWNKPEENARVLDADGWLHSEDLVSMDADGYITYAGRLKLMLKVGGENVSVEEVEKVVASHDAVAYC
GVVGVPDRRRGEVVRAYVVVRPGHCLDADILRSWLKTRLARFKVPRDIVFLDELPRLANGKLDRVGLAGRAKEEVTA

Sequences:

>Translated_557_residues
MNERPAADLAEALAELRTRTVWQMLVASAERVPDRAALVAADDGGNVQRLTYATLVERVRALSAGLASIGVRRGDRVVLW
LTNTPEWVVSHFACMRLGAVTVPVNTFLKPAEVSYVITQSGARHVILLDGFRALRMPAMLAEICPEFATADLPGHLLSAG
IPDLRNVVIFHRGGGRHGGAFDLGALEALGRDPSAADARGLADRLERQVLGSDLAMVKYTSGSTGFPKGVMLEQGGIVAN
AALHSRRIGIGGSDVFFSMMPFFHAGGSIWGLMTMLVNGGTLVFTEAFNARLGAELIESERATVMFGVIPAEVVQAAIED
GRDLSSLRIAAVPNEDARRVMPNVTFTFVPFGLTETYGPASVTAPDDPPDKRRTTGGRPLPGNEVRVVDPATGLDVPPGA
VGEAWVRGNVMRGYWNKPEENARVLDADGWLHSEDLVSMDADGYITYAGRLKLMLKVGGENVSVEEVEKVVASHDAVAYC
GVVGVPDRRRGEVVRAYVVVRPGHCLDADILRSWLKTRLARFKVPRDIVFLDELPRLANGKLDRVGLAGRAKEEVTA
>Mature_557_residues
MNERPAADLAEALAELRTRTVWQMLVASAERVPDRAALVAADDGGNVQRLTYATLVERVRALSAGLASIGVRRGDRVVLW
LTNTPEWVVSHFACMRLGAVTVPVNTFLKPAEVSYVITQSGARHVILLDGFRALRMPAMLAEICPEFATADLPGHLLSAG
IPDLRNVVIFHRGGGRHGGAFDLGALEALGRDPSAADARGLADRLERQVLGSDLAMVKYTSGSTGFPKGVMLEQGGIVAN
AALHSRRIGIGGSDVFFSMMPFFHAGGSIWGLMTMLVNGGTLVFTEAFNARLGAELIESERATVMFGVIPAEVVQAAIED
GRDLSSLRIAAVPNEDARRVMPNVTFTFVPFGLTETYGPASVTAPDDPPDKRRTTGGRPLPGNEVRVVDPATGLDVPPGA
VGEAWVRGNVMRGYWNKPEENARVLDADGWLHSEDLVSMDADGYITYAGRLKLMLKVGGENVSVEEVEKVVASHDAVAYC
GVVGVPDRRRGEVVRAYVVVRPGHCLDADILRSWLKTRLARFKVPRDIVFLDELPRLANGKLDRVGLAGRAKEEVTA

Specific function: Unknown

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=556, Percent_Identity=30.3956834532374, Blast_Score=242, Evalue=7e-64,
Organism=Homo sapiens, GI187761345, Length=560, Percent_Identity=27.6785714285714, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI187761343, Length=560, Percent_Identity=27.6785714285714, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI38505220, Length=561, Percent_Identity=27.0944741532977, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI115511026, Length=537, Percent_Identity=24.2085661080074, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI28416953, Length=552, Percent_Identity=26.0869565217391, Blast_Score=113, Evalue=6e-25,
Organism=Homo sapiens, GI42544132, Length=551, Percent_Identity=24.5009074410163, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI122937307, Length=544, Percent_Identity=22.6102941176471, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI157311624, Length=559, Percent_Identity=23.4347048300537, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI157311622, Length=559, Percent_Identity=23.4347048300537, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI58082049, Length=559, Percent_Identity=23.0769230769231, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI38524616, Length=557, Percent_Identity=24.4165170556553, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI27477105, Length=127, Percent_Identity=33.8582677165354, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI145693145, Length=536, Percent_Identity=30.7835820895522, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI1788107, Length=578, Percent_Identity=27.8546712802768, Blast_Score=176, Evalue=5e-45,
Organism=Escherichia coli, GI221142682, Length=541, Percent_Identity=26.8022181146026, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1786810, Length=525, Percent_Identity=28.3809523809524, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1790505, Length=542, Percent_Identity=23.9852398523985, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789201, Length=391, Percent_Identity=29.156010230179, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788595, Length=342, Percent_Identity=28.9473684210526, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786529, Length=586, Percent_Identity=24.2320819112628, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786801, Length=576, Percent_Identity=23.7847222222222, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994694, Length=559, Percent_Identity=29.8747763864043, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI71994703, Length=559, Percent_Identity=29.8747763864043, Blast_Score=240, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI71994690, Length=559, Percent_Identity=29.8747763864043, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17560308, Length=557, Percent_Identity=30.3411131059246, Blast_Score=219, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17558820, Length=531, Percent_Identity=24.8587570621469, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17531443, Length=538, Percent_Identity=24.7211895910781, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI32563687, Length=529, Percent_Identity=24.952741020794, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17559526, Length=371, Percent_Identity=28.0323450134771, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17557194, Length=553, Percent_Identity=23.3273056057866, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17538037, Length=541, Percent_Identity=23.8447319778189, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71996755, Length=344, Percent_Identity=26.7441860465116, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71985884, Length=356, Percent_Identity=28.0898876404494, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17560140, Length=548, Percent_Identity=22.0802919708029, Blast_Score=93, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6319699, Length=344, Percent_Identity=28.7790697674419, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6323182, Length=585, Percent_Identity=24.957264957265, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6319264, Length=571, Percent_Identity=25.569176882662, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24581924, Length=560, Percent_Identity=30.7142857142857, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI18859661, Length=517, Percent_Identity=25.531914893617, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21355181, Length=559, Percent_Identity=25.2236135957066, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24648260, Length=368, Percent_Identity=25.2717391304348, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI45550496, Length=582, Percent_Identity=24.3986254295533, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45552801, Length=582, Percent_Identity=24.3986254295533, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356947, Length=347, Percent_Identity=26.8011527377522, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24653035, Length=355, Percent_Identity=25.0704225352113, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21356441, Length=361, Percent_Identity=26.8698060941828, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281365686, Length=337, Percent_Identity=24.9258160237389, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI20130357, Length=545, Percent_Identity=23.4862385321101, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21358303, Length=332, Percent_Identity=26.5060240963855, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17933690, Length=514, Percent_Identity=22.568093385214, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922652, Length=536, Percent_Identity=22.5746268656716, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI161076582, Length=362, Percent_Identity=24.0331491712707, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648255, Length=553, Percent_Identity=23.3273056057866, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648253, Length=553, Percent_Identity=22.9656419529837, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648257, Length=339, Percent_Identity=26.5486725663717, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: 6.2.1.3

Molecular weight: Translated: 59941; Mature: 59941

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERPAADLAEALAELRTRTVWQMLVASAERVPDRAALVAADDGGNVQRLTYATLVERVR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHHHHHHHH
ALSAGLASIGVRRGDRVVLWLTNTPEWVVSHFACMRLGAVTVPVNTFLKPAEVSYVITQS
HHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCEEECHHHCCCCCCEEEEEECC
GARHVILLDGFRALRMPAMLAEICPEFATADLPGHLLSAGIPDLRNVVIFHRGGGRHGGA
CCCEEEEECCCHHHHHHHHHHHHCHHHHCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCC
FDLGALEALGRDPSAADARGLADRLERQVLGSDLAMVKYTSGSTGFPKGVMLEQGGIVAN
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCEEEE
AALHSRRIGIGGSDVFFSMMPFFHAGGSIWGLMTMLVNGGTLVFTEAFNARLGAELIESE
HHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCC
RATVMFGVIPAEVVQAAIEDGRDLSSLRIAAVPNEDARRVMPNVTFTFVPFGLTETYGPA
CCEEEEECCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCEEEEEECCCCCCCCCC
SVTAPDDPPDKRRTTGGRPLPGNEVRVVDPATGLDVPPGAVGEAWVRGNVMRGYWNKPEE
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHCCCEEECCCCCCCC
NARVLDADGWLHSEDLVSMDADGYITYAGRLKLMLKVGGENVSVEEVEKVVASHDAVAYC
CCEEEECCCCCCCCCCEEECCCCEEEEECEEEEEEEECCCCCCHHHHHHHHHCCCCEEEE
GVVGVPDRRRGEVVRAYVVVRPGHCLDADILRSWLKTRLARFKVPRDIVFLDELPRLANG
CEECCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHCCHHHCC
KLDRVGLAGRAKEEVTA
CCCEECCCCCCHHHCCC
>Mature Secondary Structure
MNERPAADLAEALAELRTRTVWQMLVASAERVPDRAALVAADDGGNVQRLTYATLVERVR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHHHHHHHH
ALSAGLASIGVRRGDRVVLWLTNTPEWVVSHFACMRLGAVTVPVNTFLKPAEVSYVITQS
HHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCEEECHHHCCCCCCEEEEEECC
GARHVILLDGFRALRMPAMLAEICPEFATADLPGHLLSAGIPDLRNVVIFHRGGGRHGGA
CCCEEEEECCCHHHHHHHHHHHHCHHHHCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCC
FDLGALEALGRDPSAADARGLADRLERQVLGSDLAMVKYTSGSTGFPKGVMLEQGGIVAN
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCEEEE
AALHSRRIGIGGSDVFFSMMPFFHAGGSIWGLMTMLVNGGTLVFTEAFNARLGAELIESE
HHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCC
RATVMFGVIPAEVVQAAIEDGRDLSSLRIAAVPNEDARRVMPNVTFTFVPFGLTETYGPA
CCEEEEECCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCEEEEEECCCCCCCCCC
SVTAPDDPPDKRRTTGGRPLPGNEVRVVDPATGLDVPPGAVGEAWVRGNVMRGYWNKPEE
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHCCCEEECCCCCCCC
NARVLDADGWLHSEDLVSMDADGYITYAGRLKLMLKVGGENVSVEEVEKVVASHDAVAYC
CCEEEECCCCCCCCCCEEECCCCEEEEECEEEEEEEECCCCCCHHHHHHHHHCCCCEEEE
GVVGVPDRRRGEVVRAYVVVRPGHCLDADILRSWLKTRLARFKVPRDIVFLDELPRLANG
CEECCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHCCHHHCC
KLDRVGLAGRAKEEVTA
CCCEECCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; long-chain carboxylic acid; CoA

Specific reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]