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The map label for this gene is fabG [H]

Identifier: 158316327

GI number: 158316327

Start: 5434990

End: 5435757

Strand: Reverse

Name: fabG [H]

Synonym: Franean1_4556

Alternate gene names: 158316327

Gene position: 5435757-5434990 (Counterclockwise)

Preceding gene: 158316328

Following gene: 158316322

Centisome position: 60.52

GC content: 73.05

Gene sequence:

>768_bases
ATGAACCTGAAGTCCGTCCCGGCATTCGTCACCGGCGGCTCGTCCGGCCTGGGCCTGGCGACCGCGCGACGGCTGGCCGC
CGCGGGAGCGGAGGTCGCGATCGCCGATCTCAACCCGCCGGGAGAGGACGTCCTCGCCGCGCTCGGCGACCGGGCCGTCT
ACATCGAGACCGACGTCGCCGACGAGGCCTCGGTGAACCACGCCCTGGACGTGGCCCAGCAGGCGCACGGCACGCTGCGC
GCGGTCGTGCACTGCGCCGGTCGCGGCGGAGACCGCGTCCGCATCCTCGACCGGGACGACCGGCCGGGTGCCCTGGACAC
CTTCGCCGAAGTCGTGCGGGTGAACCTGATCGGCACCTACAACGTCCTGCGCCTGGCGGCCGCGCGGATCGCCGCGGGCG
AGATCGTCGACGGCGAGCGTGGCGCCGTCGTGCTGACGGCCTCGGTCGCCGCGTTCGACGGCCAGATCGGGCAGACGTCC
TACACCGCGGCGAAGGCTGGTGTGCACGGGATCACGCTCGTGGCCGCGCGCGACCTGGCCAGCCGGCAGATCCGCGTCAA
CACGATCGCGCCCGGCGTCTTCGACACCCCGATGCTGGCCCGGCTGCGCGCGGACATCCGCGAGGCGCTCGAGCGCACCG
TGCCCCATCCCAGTCGGCTCGGCTCACCCGAGGACTACGCCCACATGGCGATCAGCCTGCTCGAGAACCCGTATGTGAAC
GGCGAGACCGTCCGGCTGGACGGGGCCATCCGGATGGCCGCTCGCTGA

Upstream 100 bases:

>100_bases
GGCCAACGCGACCGTCATCGAGCTGATCGGTGCCTGAGGCCGGGCCGGGCCCGGGCCGCGGCATCGACGGTTTCTCCCGC
CCGTCGCCCCGAGGAGCGTC

Downstream 100 bases:

>100_bases
ACCGTCCCGTCCGCCGGCCGCCGGCGAAACCCGCCTGAACGTCCGTCCGAAACGGGTCCGGCGGCCGGCGCGCCGGCCGG
GTCAGGAGAACAGCTCGACG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNLKSVPAFVTGGSSGLGLATARRLAAAGAEVAIADLNPPGEDVLAALGDRAVYIETDVADEASVNHALDVAQQAHGTLR
AVVHCAGRGGDRVRILDRDDRPGALDTFAEVVRVNLIGTYNVLRLAAARIAAGEIVDGERGAVVLTASVAAFDGQIGQTS
YTAAKAGVHGITLVAARDLASRQIRVNTIAPGVFDTPMLARLRADIREALERTVPHPSRLGSPEDYAHMAISLLENPYVN
GETVRLDGAIRMAAR

Sequences:

>Translated_255_residues
MNLKSVPAFVTGGSSGLGLATARRLAAAGAEVAIADLNPPGEDVLAALGDRAVYIETDVADEASVNHALDVAQQAHGTLR
AVVHCAGRGGDRVRILDRDDRPGALDTFAEVVRVNLIGTYNVLRLAAARIAAGEIVDGERGAVVLTASVAAFDGQIGQTS
YTAAKAGVHGITLVAARDLASRQIRVNTIAPGVFDTPMLARLRADIREALERTVPHPSRLGSPEDYAHMAISLLENPYVN
GETVRLDGAIRMAAR
>Mature_255_residues
MNLKSVPAFVTGGSSGLGLATARRLAAAGAEVAIADLNPPGEDVLAALGDRAVYIETDVADEASVNHALDVAQQAHGTLR
AVVHCAGRGGDRVRILDRDDRPGALDTFAEVVRVNLIGTYNVLRLAAARIAAGEIVDGERGAVVLTASVAAFDGQIGQTS
YTAAKAGVHGITLVAARDLASRQIRVNTIAPGVFDTPMLARLRADIREALERTVPHPSRLGSPEDYAHMAISLLENPYVN
GETVRLDGAIRMAAR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=45.8498023715415, Blast_Score=211, Evalue=7e-55,
Organism=Homo sapiens, GI83715985, Length=253, Percent_Identity=43.0830039525692, Blast_Score=191, Evalue=5e-49,
Organism=Homo sapiens, GI15277342, Length=266, Percent_Identity=31.9548872180451, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=29.2682926829268, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=29.718875502008, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI31542939, Length=267, Percent_Identity=26.5917602996255, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=32.03125, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=30.9803921568627, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=29.9610894941634, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=27.6264591439689, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=29.3172690763052, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=29.2, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=27.8884462151394, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=25.296442687747, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=42.6877470355731, Blast_Score=190, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=31.8897637795276, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=30, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=27.734375, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=272, Percent_Identity=27.2058823529412, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=206, Percent_Identity=29.126213592233, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=47.6190476190476, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=34.9019607843137, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=27.4809160305344, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357041, Length=263, Percent_Identity=27.3764258555133, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26643; Mature: 26643

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKSVPAFVTGGSSGLGLATARRLAAAGAEVAIADLNPPGEDVLAALGDRAVYIETDVA
CCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCEEEEEECCC
DEASVNHALDVAQQAHGTLRAVVHCAGRGGDRVRILDRDDRPGALDTFAEVVRVNLIGTY
CCHHHHHHHHHHHHHHHHHEEHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHH
NVLRLAAARIAAGEIVDGERGAVVLTASVAAFDGQIGQTSYTAAKAGVHGITLVAARDLA
HHHHHHHHHHHHCCEECCCCCEEEEEEEEEECCCCCCCCHHHHHHCCCCEEEEEEHHHHH
SRQIRVNTIAPGVFDTPMLARLRADIREALERTVPHPSRLGSPEDYAHMAISLLENPYVN
CCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHCCCCC
GETVRLDGAIRMAAR
CCEEEECCEEEECCC
>Mature Secondary Structure
MNLKSVPAFVTGGSSGLGLATARRLAAAGAEVAIADLNPPGEDVLAALGDRAVYIETDVA
CCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCEEEEEECCC
DEASVNHALDVAQQAHGTLRAVVHCAGRGGDRVRILDRDDRPGALDTFAEVVRVNLIGTY
CCHHHHHHHHHHHHHHHHHEEHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHH
NVLRLAAARIAAGEIVDGERGAVVLTASVAAFDGQIGQTSYTAAKAGVHGITLVAARDLA
HHHHHHHHHHHHCCEECCCCCEEEEEEEEEECCCCCCCCHHHHHHCCCCEEEEEEHHHHH
SRQIRVNTIAPGVFDTPMLARLRADIREALERTVPHPSRLGSPEDYAHMAISLLENPYVN
CCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHCCCCC
GETVRLDGAIRMAAR
CCEEEECCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]